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The map label for this gene is arsC [H]

Identifier: 103487884

GI number: 103487884

Start: 2538708

End: 2539136

Strand: Direct

Name: arsC [H]

Synonym: Sala_2404

Alternate gene names: 103487884

Gene position: 2538708-2539136 (Clockwise)

Preceding gene: 103487883

Following gene: 103487885

Centisome position: 75.89

GC content: 65.27

Gene sequence:

>429_bases
ATGACCGACATCGTCATCTACCATAACCCCGCCTGCGGGACCTCCCGCAACACCCTCGCGATGATTCGCAATGCCGGGAT
CGAACCGCATGTCGTCGAGTATCTGAAGACGCCGCCGTCGCGTGCGCTGCTCGAACAGTTGATCGTCCGCGCCGGCATCA
CGGCTCGCGAACTCCTGCGAGAGAAAGGCACGCCCTATGCGGAGCTGGGGCTCGGAGACATGGCCCTTGGCGACGAAGCG
CTGATCGACGCGATGATGGCGCATCCCGCCCTGATCAACCGCCCGTTGGTGGTCTCGCCGCTCGGCGTGAAGCTCTGCCG
TCCCTCCGAAACGGTACTCGACCTCATCCCTGCGGGGCAACGCGGCGCCTTCGCCAAGGAAGACGGCGAACAGGTAATCG
ACGCCGCTGGCAACCGCGTCGGCGCCTGA

Upstream 100 bases:

>100_bases
GGCCTGATGCTCTTCCTGGCGAAGGACTGCTGCCAAGGCCGGGCGGAGCTGTGCGAGCCGCTGCTCGCAGAACTCGCCTG
CTGCTGAAGGAACGCGCGCT

Downstream 100 bases:

>100_bases
GCCAAGCCGATGACAGAACCCAAGCGGGAACGGCTGTCGTTCCTCGATCGCTATCTCACCCTCTGGATCTTCCTCGCGAT
GGCGCTCGGCGTGTTGCTCG

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MTDIVIYHNPACGTSRNTLAMIRNAGIEPHVVEYLKTPPSRALLEQLIVRAGITARELLREKGTPYAELGLGDMALGDEA
LIDAMMAHPALINRPLVVSPLGVKLCRPSETVLDLIPAGQRGAFAKEDGEQVIDAAGNRVGA

Sequences:

>Translated_142_residues
MTDIVIYHNPACGTSRNTLAMIRNAGIEPHVVEYLKTPPSRALLEQLIVRAGITARELLREKGTPYAELGLGDMALGDEA
LIDAMMAHPALINRPLVVSPLGVKLCRPSETVLDLIPAGQRGAFAKEDGEQVIDAAGNRVGA
>Mature_141_residues
TDIVIYHNPACGTSRNTLAMIRNAGIEPHVVEYLKTPPSRALLEQLIVRAGITARELLREKGTPYAELGLGDMALGDEAL
IDAMMAHPALINRPLVVSPLGVKLCRPSETVLDLIPAGQRGAFAKEDGEQVIDAAGNRVGA

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=140, Percent_Identity=60, Blast_Score=186, Evalue=4e-49,
Organism=Escherichia coli, GI1788841, Length=114, Percent_Identity=45.6140350877193, Blast_Score=103, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 15150; Mature: 15019

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDIVIYHNPACGTSRNTLAMIRNAGIEPHVVEYLKTPPSRALLEQLIVRAGITARELLR
CCCEEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHH
EKGTPYAELGLGDMALGDEALIDAMMAHPALINRPLVVSPLGVKLCRPSETVLDLIPAGQ
HCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCEEECCCHHHHHHCCCCC
RGAFAKEDGEQVIDAAGNRVGA
CCCCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TDIVIYHNPACGTSRNTLAMIRNAGIEPHVVEYLKTPPSRALLEQLIVRAGITARELLR
CCEEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHH
EKGTPYAELGLGDMALGDEALIDAMMAHPALINRPLVVSPLGVKLCRPSETVLDLIPAGQ
HCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCEEECCCHHHHHHCCCCC
RGAFAKEDGEQVIDAAGNRVGA
CCCCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3021763; 1703401; 1704144 [H]