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The map label for this gene is ycfF [C]

Identifier: 103487862

GI number: 103487862

Start: 2503973

End: 2504350

Strand: Direct

Name: ycfF [C]

Synonym: Sala_2381

Alternate gene names: 103487862

Gene position: 2503973-2504350 (Clockwise)

Preceding gene: 103487861

Following gene: 103487863

Centisome position: 74.85

GC content: 68.52

Gene sequence:

>378_bases
ATGCCGATCGACGCCACCCTCCCCTATGACGACAGCAACATCTTCGCGCGCATCCTGCGCGGTGAGCTGCCGGCGAAGAC
CGTCTATGACGACGAATATGCCCTCGCCTTCCACGACATCAACCCGCAGGCGCCGCTGCACATCCTCGTCATCCCCAAGG
GCGCCTATGTCAGCTGGGACGATTTTTCGGAGCGCGGCAGCGACGCCGAAATCGCGGGCTTCGTCCGCGCGGTGGGCCGC
GTCGCGCGCGACCAGGGCCTCGTCGCCCCCGGCTATCGCCTGCTCGCCAACGTCGGGCCCGACAGCCATCAGGAGGTGCC
GCACCTCCACGTCCACATCTTCGCCGGCCGCCCGCTCGGCCCGATGCTCGCGCGATAG

Upstream 100 bases:

>100_bases
CGTCATCCCGGCGAAGGCCGGGATCTCGCCGGTGCGTCAATCCGATTGGGTGAGATCCCGGCCTTCGCCGGGATGACGCA
GCGGACAAAAGGAAGCCCCC

Downstream 100 bases:

>100_bases
CCCCAACGCAAGGCGCGGCGACGGGTGGACTCATCCCTCGCTTTCCAGCAGGATAGACGTGCGGGCCAGCGACGGGAGGC
GGGGCGATGACGACAGCGTG

Product: histidine triad (HIT) protein

Products: ADP

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 125; Mature: 124

Protein sequence:

>125_residues
MPIDATLPYDDSNIFARILRGELPAKTVYDDEYALAFHDINPQAPLHILVIPKGAYVSWDDFSERGSDAEIAGFVRAVGR
VARDQGLVAPGYRLLANVGPDSHQEVPHLHVHIFAGRPLGPMLAR

Sequences:

>Translated_125_residues
MPIDATLPYDDSNIFARILRGELPAKTVYDDEYALAFHDINPQAPLHILVIPKGAYVSWDDFSERGSDAEIAGFVRAVGR
VARDQGLVAPGYRLLANVGPDSHQEVPHLHVHIFAGRPLGPMLAR
>Mature_124_residues
PIDATLPYDDSNIFARILRGELPAKTVYDDEYALAFHDINPQAPLHILVIPKGAYVSWDDFSERGSDAEIAGFVRAVGRV
ARDQGLVAPGYRLLANVGPDSHQEVPHLHVHIFAGRPLGPMLAR

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=108, Percent_Identity=44.4444444444444, Blast_Score=89, Evalue=6e-19,
Organism=Homo sapiens, GI14211923, Length=108, Percent_Identity=41.6666666666667, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787346, Length=114, Percent_Identity=41.2280701754386, Blast_Score=91, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17506713, Length=112, Percent_Identity=41.9642857142857, Blast_Score=92, Evalue=7e-20,
Organism=Drosophila melanogaster, GI28574010, Length=115, Percent_Identity=42.6086956521739, Blast_Score=88, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24581222, Length=115, Percent_Identity=42.6086956521739, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: 3.6.1.41

Molecular weight: Translated: 13739; Mature: 13608

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIDATLPYDDSNIFARILRGELPAKTVYDDEYALAFHDINPQAPLHILVIPKGAYVSWD
CCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCEEEEEECCCCCCCEEEEEECCCCEECCC
DFSERGSDAEIAGFVRAVGRVARDQGLVAPGYRLLANVGPDSHQEVPHLHVHIFAGRPLG
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEEEEECCCCC
PMLAR
CCCCC
>Mature Secondary Structure 
PIDATLPYDDSNIFARILRGELPAKTVYDDEYALAFHDINPQAPLHILVIPKGAYVSWD
CCCCCCCCCCHHHHHHHHHCCCCCCEEECCCEEEEEECCCCCCCEEEEEECCCCEECCC
DFSERGSDAEIAGFVRAVGRVARDQGLVAPGYRLLANVGPDSHQEVPHLHVHIFAGRPLG
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEEEEECCCCC
PMLAR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: P1,P4-bis(5'-adenosyl) tetraphosphate; H2O

Specific reaction: P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2664449; 1472710 [H]