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The map label for this gene is recQ [H]

Identifier: 103487816

GI number: 103487816

Start: 2463004

End: 2464785

Strand: Reverse

Name: recQ [H]

Synonym: Sala_2335

Alternate gene names: 103487816

Gene position: 2464785-2463004 (Counterclockwise)

Preceding gene: 103487817

Following gene: 103487815

Centisome position: 73.68

GC content: 69.47

Gene sequence:

>1782_bases
ATGTCCTCTCCCGCCGACGCGCTCCTCCCGCTGCTCAAATCCACCTTCGGCTTCGACGCCTTTCGGGGCCGTCAGGGCGA
GGTGGTCGCGCGGGTGATGGCGGGCGAGCGCACGCTGGCGGTGATGCCGACGGGGGCAGGAAAATCGCTGACCTATCAAT
TGCCCGCTGTGGCGCTGGAGGGCTGCGTCGTCGTCGTGTCGCCGCTGATCGCGCTGATGCACGACCAGCTGCGCGGCGCG
CGCGCGGCGGGAATAAGAGCAGCGTCGCTCACCAGCGTCGATGCCGATTTCGCCGACACGCGGCAGGCCTATCGCGACGG
GCAGCTCGACCTTCTCTATATCACGCCCGAGCGCGCGACGGGCGAGGGCTTCCGCTCGCTCATGGAAGCGCGCGCACCTG
CGCTGTTCGCGATCGACGAGGCGCATTGCGTTTCGGAATGGGGGCATGATTTCCGCCCCGATTACCGGCTGCTCAGGCCG
CTTCTCGATGCCTTTCCCGACGTTCCGCGGCTCGCGCTGACGGCGACCGCCGACAAGCATACGCGCGAGGATATTCTCGT
CCAGCTGGGCATTCCGGCCGAGGGGCTGGTGCTCGCGGGCTTCGACCGGCCGAATATCCGCTATCGGGTAACACCGCGGG
TGAGCCCGGCGAAGCAGCTGGCCGATTTCATCGCCGCCAATCCGGGGCCGGGGATCGTCTATTGCCCGACGCGCGACGGG
ACCGAACGCATGGCCGAAAGGCTCGCCGCCGCGACGGGGCGCAGCGTTGCCGCCTATCACGCCGGGCTGGACCCCGAGCG
GCGCGCGCGGGTGCAGCATGATTTTGTCGCGTCGGAGGACGGCATCGTCACGGCGACGGTCGCCTTCGGCATGGGGATCG
ACAAGCCCGACGTGCGTTTCGTCGCGCACGCGGGCCTGCCGAAATCGATCGAAAGCTATTATCAGGAAACGGGCCGCGCG
GGGCGCGACGGCGACCCGGCCGAGGCGCTGATGCTGTGGGCCGCCGATGATTTTGCGCGCGCCCGCGCGCGCTTGTCCGA
ACTGCCCGAGGCGCGCGTCGCGGCCGAACGCGCGCGCCTCAATGCGCTCGCGGCGCTGGTCGAAACGGCCCAGTGCCGCC
GCGCGCTGCTGCTCCGCCATTTCGGCGAAAATCCGCCCACACGCTGCGGCAATTGCGACACCTGCCTCGACCCGCCGAAA
CAGGTCGATGCGACGGTGCTCGCGCAGAAATTGATGAGCGCGGTCTATCGCACGGGTCAGAGTTTCGGCGCGGGCCATGT
CGAGGCGGTGCTGACGGGGCGGAGCGACGAACGGGTCGTCAGCCGCGGGCACGACAAATTGTCGGTGTTCGGAATCGTCG
AGGGCGAGGAAGCGCGGCTGATCAAGCCGCTGGTCCGCACGCTCGTCGCGCGCGAGGCGTTGCAGGCGACCGAGCATGGC
GGGCTGATGTTCGGCCCCGCCGGCCGCGCGGTGATGAAGGGCGAAGCGCCGGTGCTGATCGCCGAGCCGCCGGTGAAACG
TACGCAGCGTGCGAGCCGCAGCGACCGCGCGGCGGCCAATCCGGTCGGCGATCCGCTGTTCGAGGCACTGCGCGGCATCC
GGCGCGAGCTTGCCGCCGAGGCGGGGGTGCCGCCCTATGTCGTGTTCCACGACGCGGTGCTGCGCGCGATGGCGAGCGAG
CGCCCCGCGACGCGCAGCGATCTTGCCGCGATTCCTGGCGTCGGCGCCAAAAAACTGGAGGCGTGGGGCGATGCGTTTCT
GGATGTGATCCGGCAGTTCTGA

Upstream 100 bases:

>100_bases
CGGCGCGGTGGCGGCCTGGATGTACGGGCGCTGGTTGTTTGCCGGGGAGGCGGCGGCATAACCCCTACCGTCGCATGGCC
GCGCTTGCTAGGGCGGGGTC

Downstream 100 bases:

>100_bases
TCGTTCGAGAGCGGCCGTTAGTTGCCCTAATATCCTCCCCATCGACTTGCGATGGGGAGGTGGCAGCCCGCAGGGCTGAC
GGAGGGGCAGCGAGCGCGCA

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 593; Mature: 592

Protein sequence:

>593_residues
MSSPADALLPLLKSTFGFDAFRGRQGEVVARVMAGERTLAVMPTGAGKSLTYQLPAVALEGCVVVVSPLIALMHDQLRGA
RAAGIRAASLTSVDADFADTRQAYRDGQLDLLYITPERATGEGFRSLMEARAPALFAIDEAHCVSEWGHDFRPDYRLLRP
LLDAFPDVPRLALTATADKHTREDILVQLGIPAEGLVLAGFDRPNIRYRVTPRVSPAKQLADFIAANPGPGIVYCPTRDG
TERMAERLAAATGRSVAAYHAGLDPERRARVQHDFVASEDGIVTATVAFGMGIDKPDVRFVAHAGLPKSIESYYQETGRA
GRDGDPAEALMLWAADDFARARARLSELPEARVAAERARLNALAALVETAQCRRALLLRHFGENPPTRCGNCDTCLDPPK
QVDATVLAQKLMSAVYRTGQSFGAGHVEAVLTGRSDERVVSRGHDKLSVFGIVEGEEARLIKPLVRTLVAREALQATEHG
GLMFGPAGRAVMKGEAPVLIAEPPVKRTQRASRSDRAAANPVGDPLFEALRGIRRELAAEAGVPPYVVFHDAVLRAMASE
RPATRSDLAAIPGVGAKKLEAWGDAFLDVIRQF

Sequences:

>Translated_593_residues
MSSPADALLPLLKSTFGFDAFRGRQGEVVARVMAGERTLAVMPTGAGKSLTYQLPAVALEGCVVVVSPLIALMHDQLRGA
RAAGIRAASLTSVDADFADTRQAYRDGQLDLLYITPERATGEGFRSLMEARAPALFAIDEAHCVSEWGHDFRPDYRLLRP
LLDAFPDVPRLALTATADKHTREDILVQLGIPAEGLVLAGFDRPNIRYRVTPRVSPAKQLADFIAANPGPGIVYCPTRDG
TERMAERLAAATGRSVAAYHAGLDPERRARVQHDFVASEDGIVTATVAFGMGIDKPDVRFVAHAGLPKSIESYYQETGRA
GRDGDPAEALMLWAADDFARARARLSELPEARVAAERARLNALAALVETAQCRRALLLRHFGENPPTRCGNCDTCLDPPK
QVDATVLAQKLMSAVYRTGQSFGAGHVEAVLTGRSDERVVSRGHDKLSVFGIVEGEEARLIKPLVRTLVAREALQATEHG
GLMFGPAGRAVMKGEAPVLIAEPPVKRTQRASRSDRAAANPVGDPLFEALRGIRRELAAEAGVPPYVVFHDAVLRAMASE
RPATRSDLAAIPGVGAKKLEAWGDAFLDVIRQF
>Mature_592_residues
SSPADALLPLLKSTFGFDAFRGRQGEVVARVMAGERTLAVMPTGAGKSLTYQLPAVALEGCVVVVSPLIALMHDQLRGAR
AAGIRAASLTSVDADFADTRQAYRDGQLDLLYITPERATGEGFRSLMEARAPALFAIDEAHCVSEWGHDFRPDYRLLRPL
LDAFPDVPRLALTATADKHTREDILVQLGIPAEGLVLAGFDRPNIRYRVTPRVSPAKQLADFIAANPGPGIVYCPTRDGT
ERMAERLAAATGRSVAAYHAGLDPERRARVQHDFVASEDGIVTATVAFGMGIDKPDVRFVAHAGLPKSIESYYQETGRAG
RDGDPAEALMLWAADDFARARARLSELPEARVAAERARLNALAALVETAQCRRALLLRHFGENPPTRCGNCDTCLDPPKQ
VDATVLAQKLMSAVYRTGQSFGAGHVEAVLTGRSDERVVSRGHDKLSVFGIVEGEEARLIKPLVRTLVAREALQATEHGG
LMFGPAGRAVMKGEAPVLIAEPPVKRTQRASRSDRAAANPVGDPLFEALRGIRRELAAEAGVPPYVVFHDAVLRAMASER
PATRSDLAAIPGVGAKKLEAWGDAFLDVIRQF

Specific function: DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=642, Percent_Identity=32.398753894081, Blast_Score=302, Evalue=6e-82,
Organism=Homo sapiens, GI110735439, Length=497, Percent_Identity=35.4124748490946, Blast_Score=276, Evalue=5e-74,
Organism=Homo sapiens, GI169218196, Length=497, Percent_Identity=35.4124748490946, Blast_Score=275, Evalue=7e-74,
Organism=Homo sapiens, GI14591902, Length=402, Percent_Identity=37.5621890547264, Blast_Score=272, Evalue=6e-73,
Organism=Homo sapiens, GI14591904, Length=402, Percent_Identity=37.5621890547264, Blast_Score=272, Evalue=6e-73,
Organism=Homo sapiens, GI148612816, Length=422, Percent_Identity=38.1516587677725, Blast_Score=249, Evalue=4e-66,
Organism=Homo sapiens, GI51242943, Length=388, Percent_Identity=38.9175257731959, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI51242947, Length=388, Percent_Identity=38.9175257731959, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI284005309, Length=343, Percent_Identity=39.067055393586, Blast_Score=187, Evalue=3e-47,
Organism=Escherichia coli, GI48994977, Length=587, Percent_Identity=44.1226575809199, Blast_Score=485, Evalue=1e-138,
Organism=Caenorhabditis elegans, GI25145561, Length=499, Percent_Identity=38.877755511022, Blast_Score=297, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI32564293, Length=676, Percent_Identity=31.6568047337278, Blast_Score=286, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI71987993, Length=413, Percent_Identity=38.2566585956416, Blast_Score=275, Evalue=7e-74,
Organism=Caenorhabditis elegans, GI71987997, Length=413, Percent_Identity=38.2566585956416, Blast_Score=274, Evalue=8e-74,
Organism=Caenorhabditis elegans, GI17552866, Length=512, Percent_Identity=31.640625, Blast_Score=224, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6323844, Length=557, Percent_Identity=32.3159784560144, Blast_Score=283, Evalue=4e-77,
Organism=Drosophila melanogaster, GI24646066, Length=634, Percent_Identity=34.0694006309148, Blast_Score=330, Evalue=1e-90,
Organism=Drosophila melanogaster, GI24664226, Length=449, Percent_Identity=36.7483296213808, Blast_Score=241, Evalue=1e-63,
Organism=Drosophila melanogaster, GI24664230, Length=444, Percent_Identity=36.9369369369369, Blast_Score=238, Evalue=1e-62,
Organism=Drosophila melanogaster, GI62472181, Length=444, Percent_Identity=36.9369369369369, Blast_Score=238, Evalue=1e-62,
Organism=Drosophila melanogaster, GI21358123, Length=357, Percent_Identity=36.9747899159664, Blast_Score=184, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 63878; Mature: 63747

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPADALLPLLKSTFGFDAFRGRQGEVVARVMAGERTLAVMPTGAGKSLTYQLPAVALE
CCCCHHHHHHHHHHHCCCHHHCCCCCHHHHHHHCCCCEEEEEECCCCCCEEEECCHHHHH
GCVVVVSPLIALMHDQLRGARAAGIRAASLTSVDADFADTRQAYRDGQLDLLYITPERAT
HHHHHHHHHHHHHHHHHCCHHHHCCCHHHHCCCCCCHHHHHHHHCCCCEEEEEECCCCCC
GEGFRSLMEARAPALFAIDEAHCVSEWGHDFRPDYRLLRPLLDAFPDVPRLALTATADKH
CHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCC
TREDILVQLGIPAEGLVLAGFDRPNIRYRVTPRVSPAKQLADFIAANPGPGIVYCPTRDG
CCCCEEEEECCCCCCCEEEECCCCCCEEEECCCCCHHHHHHHHHHCCCCCCEEEECCCCC
TERMAERLAAATGRSVAAYHAGLDPERRARVQHDFVASEDGIVTATVAFGMGIDKPDVRF
HHHHHHHHHHHCCCCCEEHHCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCEE
VAHAGLPKSIESYYQETGRAGRDGDPAEALMLWAADDFARARARLSELPEARVAAERARL
EEECCCCHHHHHHHHHHCCCCCCCCHHHEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHH
NALAALVETAQCRRALLLRHFGENPPTRCGNCDTCLDPPKQVDATVLAQKLMSAVYRTGQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
SFGAGHVEAVLTGRSDERVVSRGHDKLSVFGIVEGEEARLIKPLVRTLVAREALQATEHG
CCCCCCEEEEEECCCCHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCC
GLMFGPAGRAVMKGEAPVLIAEPPVKRTQRASRSDRAAANPVGDPLFEALRGIRRELAAE
CEEECCCCCEEECCCCCEEEECCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AGVPPYVVFHDAVLRAMASERPATRSDLAAIPGVGAKKLEAWGDAFLDVIRQF
CCCCCEEHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SSPADALLPLLKSTFGFDAFRGRQGEVVARVMAGERTLAVMPTGAGKSLTYQLPAVALE
CCCHHHHHHHHHHHCCCHHHCCCCCHHHHHHHCCCCEEEEEECCCCCCEEEECCHHHHH
GCVVVVSPLIALMHDQLRGARAAGIRAASLTSVDADFADTRQAYRDGQLDLLYITPERAT
HHHHHHHHHHHHHHHHHCCHHHHCCCHHHHCCCCCCHHHHHHHHCCCCEEEEEECCCCCC
GEGFRSLMEARAPALFAIDEAHCVSEWGHDFRPDYRLLRPLLDAFPDVPRLALTATADKH
CHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCC
TREDILVQLGIPAEGLVLAGFDRPNIRYRVTPRVSPAKQLADFIAANPGPGIVYCPTRDG
CCCCEEEEECCCCCCCEEEECCCCCCEEEECCCCCHHHHHHHHHHCCCCCCEEEECCCCC
TERMAERLAAATGRSVAAYHAGLDPERRARVQHDFVASEDGIVTATVAFGMGIDKPDVRF
HHHHHHHHHHHCCCCCEEHHCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCEE
VAHAGLPKSIESYYQETGRAGRDGDPAEALMLWAADDFARARARLSELPEARVAAERARL
EEECCCCHHHHHHHHHHCCCCCCCCHHHEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHH
NALAALVETAQCRRALLLRHFGENPPTRCGNCDTCLDPPKQVDATVLAQKLMSAVYRTGQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
SFGAGHVEAVLTGRSDERVVSRGHDKLSVFGIVEGEEARLIKPLVRTLVAREALQATEHG
CCCCCCEEEEEECCCCHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCC
GLMFGPAGRAVMKGEAPVLIAEPPVKRTQRASRSDRAAANPVGDPLFEALRGIRRELAAE
CEEECCCCCEEECCCCCEEEECCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AGVPPYVVFHDAVLRAMASERPATRSDLAAIPGVGAKKLEAWGDAFLDVIRQF
CCCCCEEHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]