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The map label for this gene is erg3 [H]

Identifier: 103487813

GI number: 103487813

Start: 2460996

End: 2461910

Strand: Reverse

Name: erg3 [H]

Synonym: Sala_2332

Alternate gene names: 103487813

Gene position: 2461910-2460996 (Counterclockwise)

Preceding gene: 103487814

Following gene: 103487812

Centisome position: 73.6

GC content: 63.72

Gene sequence:

>915_bases
GTGGCTGAACTGCCCGATCCCGTCGCCTATGCGGTGCCCGGCTTCATCCTGTTGCTGATCGTCGAAATGATCGTGTCGCG
GCGCAAGGACCGGAGCCGCTATGAAGCGCGCGATACGCTGACCTCGCTGCTGCTCGGCACAGGCAGTCAGGTCGCGGGCG
CATTGGTCGGCGCGGCGGTGATCGGCATGGCGGTCTGGATCCATCAATTCCGGCTGTTCGACATCGGAATAACCTTCGGG
CAATGGTGGTGGGCGTGGATCCTCTGCTTCGTCCTCGACGACCTTGCCTATTATGCCTTTCACCGCAGCGCGCACCGCGT
GCGCTGGTTCTGGGCGAGCCATGTGATCCACCACAGTTCGCAGCACTATAATCTGTCGACCGCGCTCCGGCAGACGTGGA
CGGGCTTCTTCAGCCTTGCCTTCATCTTTCGCCTTCCGCTCTTCCTGATCGGCTTTCCGCCCGCGATGGTGTTCTTCTGC
GCGGGGCTCAACCTGATCTACCAGTTCTGGATCCATACCGAGGCGATCCGGCGGATGCCCCGATGGTTCGAGGCGGTGAT
GAACACGCCCTCGCACCACCGCGTCCATCACGGGGTGAACCCGCGCTACCTCGACGCCAATTATGCGGGCGTGTTCATCA
TCTGGGACAAGCTGTTCGGCAGCTTCGTCGCCGAACGCGACGACGAGCCGGTACGCTACGGCATCGTCAGACAGCTCGGC
AGCTTCAACATCTTGTGGGCCGCGGTGCACGAATGGGTCGGCATCGCGAAGGATGTCTGGCACGCGCCGTGGAAGCACAA
GCTGGACTATATCTGGCGCGAGCCCGGCTGGAGCCACGACGGCAGCCGCGCGACGAGCGCGATGATCAAGGAGCGCTGGG
CGGCGGGGCGGACGAGCGAGGAGGCGGCGGAGTAA

Upstream 100 bases:

>100_bases
TTCCTGACGCTGACGATGCCCGAAAAAACGTTCGGCGCGGTGACGCTGCAACTGGGGAAGGATGCGGGGATGTGGGCGAG
CCGGATGCGGGAGGTGGTGC

Downstream 100 bases:

>100_bases
TAACCGTCGCCCGCGCGAAGGCGGGGGCCGCTGGAAGTTGACGCATCCATCGCCGAGTAAGCCCTAACGCGGCCCCGCCT
TCGCGGGGGCGACGTATAGG

Product: hypothetical protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MAELPDPVAYAVPGFILLLIVEMIVSRRKDRSRYEARDTLTSLLLGTGSQVAGALVGAAVIGMAVWIHQFRLFDIGITFG
QWWWAWILCFVLDDLAYYAFHRSAHRVRWFWASHVIHHSSQHYNLSTALRQTWTGFFSLAFIFRLPLFLIGFPPAMVFFC
AGLNLIYQFWIHTEAIRRMPRWFEAVMNTPSHHRVHHGVNPRYLDANYAGVFIIWDKLFGSFVAERDDEPVRYGIVRQLG
SFNILWAAVHEWVGIAKDVWHAPWKHKLDYIWREPGWSHDGSRATSAMIKERWAAGRTSEEAAE

Sequences:

>Translated_304_residues
MAELPDPVAYAVPGFILLLIVEMIVSRRKDRSRYEARDTLTSLLLGTGSQVAGALVGAAVIGMAVWIHQFRLFDIGITFG
QWWWAWILCFVLDDLAYYAFHRSAHRVRWFWASHVIHHSSQHYNLSTALRQTWTGFFSLAFIFRLPLFLIGFPPAMVFFC
AGLNLIYQFWIHTEAIRRMPRWFEAVMNTPSHHRVHHGVNPRYLDANYAGVFIIWDKLFGSFVAERDDEPVRYGIVRQLG
SFNILWAAVHEWVGIAKDVWHAPWKHKLDYIWREPGWSHDGSRATSAMIKERWAAGRTSEEAAE
>Mature_303_residues
AELPDPVAYAVPGFILLLIVEMIVSRRKDRSRYEARDTLTSLLLGTGSQVAGALVGAAVIGMAVWIHQFRLFDIGITFGQ
WWWAWILCFVLDDLAYYAFHRSAHRVRWFWASHVIHHSSQHYNLSTALRQTWTGFFSLAFIFRLPLFLIGFPPAMVFFCA
GLNLIYQFWIHTEAIRRMPRWFEAVMNTPSHHRVHHGVNPRYLDANYAGVFIIWDKLFGSFVAERDDEPVRYGIVRQLGS
FNILWAAVHEWVGIAKDVWHAPWKHKLDYIWREPGWSHDGSRATSAMIKERWAAGRTSEEAAE

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=289, Percent_Identity=39.4463667820069, Blast_Score=182, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI25144659, Length=270, Percent_Identity=37.4074074074074, Blast_Score=155, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 35273; Mature: 35142

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELPDPVAYAVPGFILLLIVEMIVSRRKDRSRYEARDTLTSLLLGTGSQVAGALVGAAV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IGMAVWIHQFRLFDIGITFGQWWWAWILCFVLDDLAYYAFHRSAHRVRWFWASHVIHHSS
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QHYNLSTALRQTWTGFFSLAFIFRLPLFLIGFPPAMVFFCAGLNLIYQFWIHTEAIRRMP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RWFEAVMNTPSHHRVHHGVNPRYLDANYAGVFIIWDKLFGSFVAERDDEPVRYGIVRQLG
HHHHHHHCCCCCHHHHCCCCCCEECCCCCEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHC
SFNILWAAVHEWVGIAKDVWHAPWKHKLDYIWREPGWSHDGSRATSAMIKERWAAGRTSE
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCH
EAAE
HCCC
>Mature Secondary Structure 
AELPDPVAYAVPGFILLLIVEMIVSRRKDRSRYEARDTLTSLLLGTGSQVAGALVGAAV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH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HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]