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The map label for this gene is fprA [H]

Identifier: 103487791

GI number: 103487791

Start: 2438001

End: 2439305

Strand: Direct

Name: fprA [H]

Synonym: Sala_2310

Alternate gene names: 103487791

Gene position: 2438001-2439305 (Clockwise)

Preceding gene: 103487790

Following gene: 103487792

Centisome position: 72.88

GC content: 68.66

Gene sequence:

>1305_bases
ATGCGTCATGTCGCGATCGTCGGGTCGGGTCCGGCGGGCTATTACACCGCCGAAACATTGCAGAAGGCGGACGACATTGC
GGTCGACGTCATCGATCGCCTGCCCGTTCCCTATGGCCTGATCCGCACCGGCGTCGCGCCCGATCACCAGTCGATCAAGG
CGGTGTCGCGCCGTTATGAAGGCGTCGCGCTGACCGACAATGTCCGCTTCGTCGGCCATGTCGCGGTCGGTGCCGACGTC
AGTATCGCGGAGCTGGTCGCACTGTATGACGCGGTCATTCTCGCGACCGGCGCGCCGAACGACCGACCGCTGGGCATTCC
CGGCGCCGATCTGCGCGGGGTGATCGGCAGCGCCGCTTTCGTCGGCTGGTACAACGGCCATCCCGATTTCGCGCATCTCG
ATCCGCCGCTCGATGCCCCAGGCGTCGCGGTGATCGGCAACGGCAATGTCGCGCTCGACGTCGCGCGCATCCTCGCCAAG
ACGTCCGCCGAGTTCGCCGGTAGCGACATCGTCGCGCACGCGCGCACGGCGCTCGCGGCCAGCGGTGTGCGGCATATCCA
CATCCTCGGCCGCCGTGGCCCGCACCAGATCGCGATGACGCCCAAGGAGCTTGGCGAACTGGCGCACCTTGAGCGCGCGA
GCCCGCGCGTCGACCCCGCCGACCTGCCCGACGAGGGCGGCGACGCGCTGCTCGAACCGGGGATGCGCAAGTCGGTGACG
CATCTGCGCAGCTTTGCCGCCAATCCGGTCGCCAAACCGGTGACGATCGACTTCGATTTTTTCGCCATGCCCGTCGCGAT
CGAGGGCACGCACGAAAATGGCGGCCGTGTCCAGCGCGTGATCGTCGAACGAACCGAACTCGACGCCGATCTGCGCAGCC
ACGGCACGGGCGAAACCTACGCCATCGACGCGGGGCTGGTGATCAGCTGCATCGGATACCAGACCCCGCCGATCCCTGGT
GTGCCCTATGAGCATGGCCGCGGCCGCTTTGCCAATGACGAGGGGCGGATATTGCCTGGTCTCTATTGCGTCGGCTGGGC
GCGGCGCGGACCATCGGGGACGATCGGCACCAACAAGCCCGATGGCGCGCGCGTCGCCGAAATGGTGCTGGAGGATATCG
GTCGCGGTGCGGGCAAGGTGGGGCGGCCGGGGCTCGACGCGCTGCTCGCCAGCCGCGGCATCGCGCCCGTCACCTTCCGC
GACTGGCGCCGGATCGACGCGGCGGAGGTGGCCGCCGCGCTCGACGGGAGCCCGCGCGAAAAGTTCACCAGCGTCGAGGC
GATGCTCGCCGCGATCGGACGGTGA

Upstream 100 bases:

>100_bases
TCGGCAACAGTCTGCTTGCCCTGCCGCATTTCGCCGCTAGCATCGCCCGCATAACAAGGGGGCCGCGTCGCGGCGCAGGC
ACCTGCATAGGAGTGGGCTG

Downstream 100 bases:

>100_bases
GGCAGCGCATCCGCACCGCGCTGCGCTGGCTGCTCACGCTCGCTTATGGCTATGCGGGCTGGCGGCATCTGGCGACCCCA
GAGCCTTTCCTCGCGATCAC

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: NFR [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MRHVAIVGSGPAGYYTAETLQKADDIAVDVIDRLPVPYGLIRTGVAPDHQSIKAVSRRYEGVALTDNVRFVGHVAVGADV
SIAELVALYDAVILATGAPNDRPLGIPGADLRGVIGSAAFVGWYNGHPDFAHLDPPLDAPGVAVIGNGNVALDVARILAK
TSAEFAGSDIVAHARTALAASGVRHIHILGRRGPHQIAMTPKELGELAHLERASPRVDPADLPDEGGDALLEPGMRKSVT
HLRSFAANPVAKPVTIDFDFFAMPVAIEGTHENGGRVQRVIVERTELDADLRSHGTGETYAIDAGLVISCIGYQTPPIPG
VPYEHGRGRFANDEGRILPGLYCVGWARRGPSGTIGTNKPDGARVAEMVLEDIGRGAGKVGRPGLDALLASRGIAPVTFR
DWRRIDAAEVAAALDGSPREKFTSVEAMLAAIGR

Sequences:

>Translated_434_residues
MRHVAIVGSGPAGYYTAETLQKADDIAVDVIDRLPVPYGLIRTGVAPDHQSIKAVSRRYEGVALTDNVRFVGHVAVGADV
SIAELVALYDAVILATGAPNDRPLGIPGADLRGVIGSAAFVGWYNGHPDFAHLDPPLDAPGVAVIGNGNVALDVARILAK
TSAEFAGSDIVAHARTALAASGVRHIHILGRRGPHQIAMTPKELGELAHLERASPRVDPADLPDEGGDALLEPGMRKSVT
HLRSFAANPVAKPVTIDFDFFAMPVAIEGTHENGGRVQRVIVERTELDADLRSHGTGETYAIDAGLVISCIGYQTPPIPG
VPYEHGRGRFANDEGRILPGLYCVGWARRGPSGTIGTNKPDGARVAEMVLEDIGRGAGKVGRPGLDALLASRGIAPVTFR
DWRRIDAAEVAAALDGSPREKFTSVEAMLAAIGR
>Mature_434_residues
MRHVAIVGSGPAGYYTAETLQKADDIAVDVIDRLPVPYGLIRTGVAPDHQSIKAVSRRYEGVALTDNVRFVGHVAVGADV
SIAELVALYDAVILATGAPNDRPLGIPGADLRGVIGSAAFVGWYNGHPDFAHLDPPLDAPGVAVIGNGNVALDVARILAK
TSAEFAGSDIVAHARTALAASGVRHIHILGRRGPHQIAMTPKELGELAHLERASPRVDPADLPDEGGDALLEPGMRKSVT
HLRSFAANPVAKPVTIDFDFFAMPVAIEGTHENGGRVQRVIVERTELDADLRSHGTGETYAIDAGLVISCIGYQTPPIPG
VPYEHGRGRFANDEGRILPGLYCVGWARRGPSGTIGTNKPDGARVAEMVLEDIGRGAGKVGRPGLDALLASRGIAPVTFR
DWRRIDAAEVAAALDGSPREKFTSVEAMLAAIGR

Specific function: May serve as electron transfer protein and supply electrons to P450 systems [H]

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 1 family [H]

Homologues:

Organism=Homo sapiens, GI111118981, Length=452, Percent_Identity=40.2654867256637, Blast_Score=293, Evalue=3e-79,
Organism=Homo sapiens, GI111118983, Length=458, Percent_Identity=39.7379912663755, Blast_Score=287, Evalue=1e-77,
Organism=Escherichia coli, GI87082180, Length=187, Percent_Identity=28.8770053475936, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17543860, Length=443, Percent_Identity=33.4085778781038, Blast_Score=229, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6320584, Length=483, Percent_Identity=30.2277432712215, Blast_Score=201, Evalue=1e-52,
Organism=Drosophila melanogaster, GI17137178, Length=449, Percent_Identity=36.0801781737194, Blast_Score=239, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR021163
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 45665; Mature: 45665

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHVAIVGSGPAGYYTAETLQKADDIAVDVIDRLPVPYGLIRTGVAPDHQSIKAVSRRYE
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHCC
GVALTDNVRFVGHVAVGADVSIAELVALYDAVILATGAPNDRPLGIPGADLRGVIGSAAF
CEEEECCCEEEEEEEECCCCHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHCCEE
VGWYNGHPDFAHLDPPLDAPGVAVIGNGNVALDVARILAKTSAEFAGSDIVAHARTALAA
EEEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
SGVRHIHILGRRGPHQIAMTPKELGELAHLERASPRVDPADLPDEGGDALLEPGMRKSVT
CCCEEEEEECCCCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCHHHHHH
HLRSFAANPVAKPVTIDFDFFAMPVAIEGTHENGGRVQRVIVERTELDADLRSHGTGETY
HHHHHHCCCCCCCEEEEECCEEEEEEEECCCCCCCEEEEEEHHHHHCCHHHHHCCCCCEE
AIDAGLVISCIGYQTPPIPGVPYEHGRGRFANDEGRILPGLYCVGWARRGPSGTIGTNKP
EECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCC
DGARVAEMVLEDIGRGAGKVGRPGLDALLASRGIAPVTFRDWRRIDAAEVAAALDGSPRE
CHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHCCCCHH
KFTSVEAMLAAIGR
HHHHHHHHHHHHCC
>Mature Secondary Structure
MRHVAIVGSGPAGYYTAETLQKADDIAVDVIDRLPVPYGLIRTGVAPDHQSIKAVSRRYE
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHCC
GVALTDNVRFVGHVAVGADVSIAELVALYDAVILATGAPNDRPLGIPGADLRGVIGSAAF
CEEEECCCEEEEEEEECCCCHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHCCEE
VGWYNGHPDFAHLDPPLDAPGVAVIGNGNVALDVARILAKTSAEFAGSDIVAHARTALAA
EEEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
SGVRHIHILGRRGPHQIAMTPKELGELAHLERASPRVDPADLPDEGGDALLEPGMRKSVT
CCCEEEEEECCCCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCHHHHHH
HLRSFAANPVAKPVTIDFDFFAMPVAIEGTHENGGRVQRVIVERTELDADLRSHGTGETY
HHHHHHCCCCCCCEEEEECCEEEEEEEECCCCCCCEEEEEEHHHHHCCHHHHHCCCCCEE
AIDAGLVISCIGYQTPPIPGVPYEHGRGRFANDEGRILPGLYCVGWARRGPSGTIGTNKP
EECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCC
DGARVAEMVLEDIGRGAGKVGRPGLDALLASRGIAPVTFRDWRRIDAAEVAAALDGSPRE
CHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHCCCCHH
KFTSVEAMLAAIGR
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 12071965; 12614197; 12102623 [H]