Click here to switch to the map view.

The map label for this gene is typA [H]

Identifier: 103487784

GI number: 103487784

Start: 2429807

End: 2431639

Strand: Reverse

Name: typA [H]

Synonym: Sala_2303

Alternate gene names: 103487784

Gene position: 2431639-2429807 (Counterclockwise)

Preceding gene: 103487785

Following gene: 103487783

Centisome position: 72.69

GC content: 65.3

Gene sequence:

>1833_bases
ATGTCGCTCCGCAATATCGCCATTATAGCGCACGTCGATCACGGCAAAACCACGCTCGTCGACCAGCTTTTCCGCCAGTC
GGGCACCTTTCGCGACAACCAGCGCGTCGAAGAAAGAGCCATGGATTCCAATGACCTGGAGAAAGAGCGCGGGATCACCA
TCCTGGCGAAATGCACCAGCGTCGAATGGGGCGAGGGCGATGATGCGACGCGGATCAACATCGTCGACACGCCGGGCCAC
GCCGATTTCGGCGGCGAGGTCGAGCGCATCCTGAGCATGGTCGACGGCGTCATCCTGCTCGTCGACGCCGCCGAAGGGCC
GATGCCGCAGACCAAGTTCGTCACCGGCAAGGCGCTCGCGCTGGGCCTCAAACCGATCGTCGTCGTCAACAAGATCGACC
GCAGCGACGCGCGCGCCGCCGAAGTGCTCGACGAGGTGTTCGAACTGTTCCTGACGCTCGAGGCCAGTGACGAGCAGCTC
GATTTCCCGATCCTCTATGCCTCGGGCCGCGGCGGCTATGCCTCGCCCGACCCCGAAGCGCGCGACGGCACGCTGGAGCC
GCTGTTCGAAACGATCGTCCGCCATGTCCCCGCGCCGGGGCTCGACGAAAATGCGCCCTTCACCTTCCTCGCGACGCTGC
TCGACCGCGACAATTTCATCGGCCGGATCCTGACCGGCCGCGTCCAGTCGGGGTCGGTCAAGGTCAACCAGCCGATCCAC
GCGCTCGACATGGACGGCAAGGTGATCGAAACCGGTCGCGCGTCGAAACTGCTCGCCTTCCGCGGGCTCGACCGCGTCCC
CGTCGACGAGGCGAAGGCGGGCGACATCGTCGCGATCGCGGGGCTGGCGCAGGCGACCGTCGCGAACACCATCGCCGACA
CCAGCGTGACCGAGCCGATCGCCGCGCAGCCGATCGACCCGCCGACGCTGTCGATGCGCTTTGCCGTCAACGATTCGCCG
ATGGCGGGCCGCGAGGGCAGCAAGGTGACGAGCCGCATGATCCGCGACCGGCTGTACCGCGAAGCCGAAACCAATGTCGC
GATCCGCATCACCGAAAGCGCCGACAAGGACAGTTTCGAGGTCGCCGGCCGCGGCGAGCTTCAGCTCGGCGTGCTCATCG
AAACGATGCGCCGCGAAGGCTTCGAACTCGGCATCAGCCGCCCGCGCGTCCTCTATCAGACCGACGAGAGCGGCCAGCGC
ACCGAGCCCTATGAAACCGTCGTCATCGACGTCGACGACGAGCATAGCGGCACGGTGGTCGAGAAGATGCAGCTGCGCAA
GGCCGACCTCACCGACATGCGCCCGTCGGGCGGCGGCAAGACGCGCATCACCTTCAGCGGCCCCTCGCGCGGCCTGATCG
GCTATCATGGCGAGTTTCTGTCGGACACGCGCGGCACCGGCATCATGAACCGCCTGTTCGAGAAATATGGCCCGTACAAG
GGCGTGATCGAGGGCCGCAAGAATGGCGTCCTCATCTCGAACGGCAATGGCGAAGCGGTGGCCTATGCGCTCGGCCCGCT
CGAAGAGCGCGGCATCCTCTTCGTCTCGCCCGGCGAGGCGCTCTATGAGGGGATGATCATCGGCGAGAATGCCAAGCCCG
AAGACCTTGAGGTCAACCCGATGAAGTCGAAACAGCTCACCAACTTCCGTTCGACGGGCAAGGACGATGCGATCCGCCTG
ACGCCGCCGCGGCGCATGACGCTCGAACAGGCGATCGCCTATATCGACGATGACGAGATGGTCGAGGTGACGCCGAAGAA
CATCCGCATCCGCAAGGCGATCCTCGACCCGCACGAGCGCAAGAAGGCGAGCCGCAAGAAGGAAGCGGCGTAA

Upstream 100 bases:

>100_bases
TCCGGCCAACCTCGCTTTTGTTGCGCCGCAGCAGGATAATCGCTAAGGGCGCGCCCAGCCACGGCGCTGCCGCTCATCTC
CACAAAAGGCCTTTTTTTCC

Downstream 100 bases:

>100_bases
GATACAGACCGGCGGCCCGAAACGGCCGCCGGTTTTTCTTTTGAGTGCGGCGGCCCGCTTTCCTGTTCACGCGCGCCCTT
TCCGCTCGCGCCTCGCTGTC

Product: GTP-binding protein TypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 610; Mature: 609

Protein sequence:

>610_residues
MSLRNIAIIAHVDHGKTTLVDQLFRQSGTFRDNQRVEERAMDSNDLEKERGITILAKCTSVEWGEGDDATRINIVDTPGH
ADFGGEVERILSMVDGVILLVDAAEGPMPQTKFVTGKALALGLKPIVVVNKIDRSDARAAEVLDEVFELFLTLEASDEQL
DFPILYASGRGGYASPDPEARDGTLEPLFETIVRHVPAPGLDENAPFTFLATLLDRDNFIGRILTGRVQSGSVKVNQPIH
ALDMDGKVIETGRASKLLAFRGLDRVPVDEAKAGDIVAIAGLAQATVANTIADTSVTEPIAAQPIDPPTLSMRFAVNDSP
MAGREGSKVTSRMIRDRLYREAETNVAIRITESADKDSFEVAGRGELQLGVLIETMRREGFELGISRPRVLYQTDESGQR
TEPYETVVIDVDDEHSGTVVEKMQLRKADLTDMRPSGGGKTRITFSGPSRGLIGYHGEFLSDTRGTGIMNRLFEKYGPYK
GVIEGRKNGVLISNGNGEAVAYALGPLEERGILFVSPGEALYEGMIIGENAKPEDLEVNPMKSKQLTNFRSTGKDDAIRL
TPPRRMTLEQAIAYIDDDEMVEVTPKNIRIRKAILDPHERKKASRKKEAA

Sequences:

>Translated_610_residues
MSLRNIAIIAHVDHGKTTLVDQLFRQSGTFRDNQRVEERAMDSNDLEKERGITILAKCTSVEWGEGDDATRINIVDTPGH
ADFGGEVERILSMVDGVILLVDAAEGPMPQTKFVTGKALALGLKPIVVVNKIDRSDARAAEVLDEVFELFLTLEASDEQL
DFPILYASGRGGYASPDPEARDGTLEPLFETIVRHVPAPGLDENAPFTFLATLLDRDNFIGRILTGRVQSGSVKVNQPIH
ALDMDGKVIETGRASKLLAFRGLDRVPVDEAKAGDIVAIAGLAQATVANTIADTSVTEPIAAQPIDPPTLSMRFAVNDSP
MAGREGSKVTSRMIRDRLYREAETNVAIRITESADKDSFEVAGRGELQLGVLIETMRREGFELGISRPRVLYQTDESGQR
TEPYETVVIDVDDEHSGTVVEKMQLRKADLTDMRPSGGGKTRITFSGPSRGLIGYHGEFLSDTRGTGIMNRLFEKYGPYK
GVIEGRKNGVLISNGNGEAVAYALGPLEERGILFVSPGEALYEGMIIGENAKPEDLEVNPMKSKQLTNFRSTGKDDAIRL
TPPRRMTLEQAIAYIDDDEMVEVTPKNIRIRKAILDPHERKKASRKKEAA
>Mature_609_residues
SLRNIAIIAHVDHGKTTLVDQLFRQSGTFRDNQRVEERAMDSNDLEKERGITILAKCTSVEWGEGDDATRINIVDTPGHA
DFGGEVERILSMVDGVILLVDAAEGPMPQTKFVTGKALALGLKPIVVVNKIDRSDARAAEVLDEVFELFLTLEASDEQLD
FPILYASGRGGYASPDPEARDGTLEPLFETIVRHVPAPGLDENAPFTFLATLLDRDNFIGRILTGRVQSGSVKVNQPIHA
LDMDGKVIETGRASKLLAFRGLDRVPVDEAKAGDIVAIAGLAQATVANTIADTSVTEPIAAQPIDPPTLSMRFAVNDSPM
AGREGSKVTSRMIRDRLYREAETNVAIRITESADKDSFEVAGRGELQLGVLIETMRREGFELGISRPRVLYQTDESGQRT
EPYETVVIDVDDEHSGTVVEKMQLRKADLTDMRPSGGGKTRITFSGPSRGLIGYHGEFLSDTRGTGIMNRLFEKYGPYKG
VIEGRKNGVLISNGNGEAVAYALGPLEERGILFVSPGEALYEGMIIGENAKPEDLEVNPMKSKQLTNFRSTGKDDAIRLT
PPRRMTLEQAIAYIDDDEMVEVTPKNIRIRKAILDPHERKKASRKKEAA

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI94966754, Length=133, Percent_Identity=42.8571428571429, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI157426893, Length=311, Percent_Identity=30.8681672025724, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI4503483, Length=161, Percent_Identity=35.4037267080745, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI18390331, Length=149, Percent_Identity=36.9127516778523, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI310132016, Length=111, Percent_Identity=40.5405405405405, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI310110807, Length=111, Percent_Identity=40.5405405405405, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI310123363, Length=111, Percent_Identity=40.5405405405405, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI19923640, Length=164, Percent_Identity=34.7560975609756, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI25306283, Length=164, Percent_Identity=34.7560975609756, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI25306287, Length=164, Percent_Identity=34.7560975609756, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI34147630, Length=236, Percent_Identity=30.5084745762712, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI217272892, Length=173, Percent_Identity=33.5260115606936, Blast_Score=81, Evalue=4e-15,
Organism=Homo sapiens, GI217272894, Length=173, Percent_Identity=33.5260115606936, Blast_Score=81, Evalue=4e-15,
Organism=Homo sapiens, GI94966752, Length=85, Percent_Identity=41.1764705882353, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI48994988, Length=604, Percent_Identity=53.9735099337748, Blast_Score=652, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=475, Percent_Identity=27.3684210526316, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1789738, Length=148, Percent_Identity=37.8378378378378, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790412, Length=280, Percent_Identity=31.4285714285714, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789737, Length=280, Percent_Identity=31.4285714285714, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790835, Length=150, Percent_Identity=34, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17557151, Length=239, Percent_Identity=33.4728033472803, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17556745, Length=146, Percent_Identity=36.986301369863, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17533571, Length=148, Percent_Identity=41.2162162162162, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17506493, Length=173, Percent_Identity=32.9479768786127, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71988819, Length=132, Percent_Identity=37.8787878787879, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71988811, Length=132, Percent_Identity=37.8787878787879, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17552882, Length=185, Percent_Identity=30.8108108108108, Blast_Score=83, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17556456, Length=287, Percent_Identity=27.1777003484321, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25141371, Length=278, Percent_Identity=25.5395683453237, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323320, Length=496, Percent_Identity=26.6129032258064, Blast_Score=117, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6324707, Length=146, Percent_Identity=39.041095890411, Blast_Score=106, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6320593, Length=146, Percent_Identity=39.041095890411, Blast_Score=106, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6323098, Length=155, Percent_Identity=36.7741935483871, Blast_Score=98, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6324761, Length=275, Percent_Identity=30.9090909090909, Blast_Score=90, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322359, Length=152, Percent_Identity=34.8684210526316, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324166, Length=181, Percent_Identity=34.2541436464088, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI78706572, Length=401, Percent_Identity=29.1770573566085, Blast_Score=112, Evalue=9e-25,
Organism=Drosophila melanogaster, GI28574573, Length=158, Percent_Identity=38.6075949367089, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24582462, Length=149, Percent_Identity=37.5838926174497, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24585711, Length=187, Percent_Identity=34.2245989304813, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24585713, Length=187, Percent_Identity=34.2245989304813, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24585709, Length=187, Percent_Identity=34.2245989304813, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21357743, Length=190, Percent_Identity=35.7894736842105, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281363316, Length=307, Percent_Identity=28.0130293159609, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17864358, Length=307, Percent_Identity=28.0130293159609, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI221458488, Length=164, Percent_Identity=35.9756097560976, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI19921738, Length=240, Percent_Identity=29.5833333333333, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 66799; Mature: 66667

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRNIAIIAHVDHGKTTLVDQLFRQSGTFRDNQRVEERAMDSNDLEKERGITILAKCTS
CCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHCCCEEEEEECC
VEWGEGDDATRINIVDTPGHADFGGEVERILSMVDGVILLVDAAEGPMPQTKFVTGKALA
CCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCEEECCCEEE
LGLKPIVVVNKIDRSDARAAEVLDEVFELFLTLEASDEQLDFPILYASGRGGYASPDPEA
ECCCEEEEEECCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCEEEEECCCCCCCCCCCCC
RDGTLEPLFETIVRHVPAPGLDENAPFTFLATLLDRDNFIGRILTGRVQSGSVKVNQPIH
CCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHHEECCCCCCCEEECCCEE
ALDMDGKVIETGRASKLLAFRGLDRVPVDEAKAGDIVAIAGLAQATVANTIADTSVTEPI
EECCCCCEEECCCCCEEHHHCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHCCCCCCCC
AAQPIDPPTLSMRFAVNDSPMAGREGSKVTSRMIRDRLYREAETNVAIRITESADKDSFE
CCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEE
VAGRGELQLGVLIETMRREGFELGISRPRVLYQTDESGQRTEPYETVVIDVDDEHSGTVV
ECCCCCEEHHHHHHHHHHCCCEECCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCHHH
EKMQLRKADLTDMRPSGGGKTRITFSGPSRGLIGYHGEFLSDTRGTGIMNRLFEKYGPYK
HHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCEEECCCHHCCCCCCHHHHHHHHHHCCCC
GVIEGRKNGVLISNGNGEAVAYALGPLEERGILFVSPGEALYEGMIIGENAKPEDLEVNP
CEECCCCCCEEEECCCCCEEEEEECCCCCCCEEEECCCHHHHCCEEECCCCCCCCEECCC
MKSKQLTNFRSTGKDDAIRLTPPRRMTLEQAIAYIDDDEMVEVTPKNIRIRKAILDPHER
CCHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCCEEEECCCCEEEEEHHCCCHHH
KKASRKKEAA
HHHHHHHCCC
>Mature Secondary Structure 
SLRNIAIIAHVDHGKTTLVDQLFRQSGTFRDNQRVEERAMDSNDLEKERGITILAKCTS
CCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHCCCEEEEEECC
VEWGEGDDATRINIVDTPGHADFGGEVERILSMVDGVILLVDAAEGPMPQTKFVTGKALA
CCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCEEECCCEEE
LGLKPIVVVNKIDRSDARAAEVLDEVFELFLTLEASDEQLDFPILYASGRGGYASPDPEA
ECCCEEEEEECCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCEEEEECCCCCCCCCCCCC
RDGTLEPLFETIVRHVPAPGLDENAPFTFLATLLDRDNFIGRILTGRVQSGSVKVNQPIH
CCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHHEECCCCCCCEEECCCEE
ALDMDGKVIETGRASKLLAFRGLDRVPVDEAKAGDIVAIAGLAQATVANTIADTSVTEPI
EECCCCCEEECCCCCEEHHHCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHCCCCCCCC
AAQPIDPPTLSMRFAVNDSPMAGREGSKVTSRMIRDRLYREAETNVAIRITESADKDSFE
CCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEE
VAGRGELQLGVLIETMRREGFELGISRPRVLYQTDESGQRTEPYETVVIDVDDEHSGTVV
ECCCCCEEHHHHHHHHHHCCCEECCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCHHH
EKMQLRKADLTDMRPSGGGKTRITFSGPSRGLIGYHGEFLSDTRGTGIMNRLFEKYGPYK
HHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCEEECCCHHCCCCCCHHHHHHHHHHCCCC
GVIEGRKNGVLISNGNGEAVAYALGPLEERGILFVSPGEALYEGMIIGENAKPEDLEVNP
CEECCCCCCEEEECCCCCEEEEEECCCCCCCEEEECCCHHHHCCEEECCCCCCCCEECCC
MKSKQLTNFRSTGKDDAIRLTPPRRMTLEQAIAYIDDDEMVEVTPKNIRIRKAILDPHER
CCHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCCEEEECCCCEEEEEHHCCCHHH
KKASRKKEAA
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]