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The map label for this gene is sdhB [H]

Identifier: 103487715

GI number: 103487715

Start: 2347216

End: 2347998

Strand: Reverse

Name: sdhB [H]

Synonym: Sala_2234

Alternate gene names: 103487715

Gene position: 2347998-2347216 (Counterclockwise)

Preceding gene: 103487721

Following gene: 103487714

Centisome position: 70.19

GC content: 62.58

Gene sequence:

>783_bases
ATGGCCGAATTCCGCCTGCCCAAGAACAGCCGCCCGCAAAAGGGCGGCAAGGTCCACAAGGCCGAAGGCGCGACCCACGT
CAAACGGTTCAAAGTCTATCGCTACGATCCCGACAAGGGGCAGAACCCGCATTTCGACACGTTCGAGATCGACACCGAGA
AATGTGGCCCGATGGTGCTCGACGCGCTCATCAAGATGAAGAGCGAGCAGGATTCGACGCTGACCTTCCGCCGTTCGTGC
CGCGAAGGCATCTGCGGCAGCTGTTCGATGAACATGAACGGCAAGAACGGCCTCGCCTGCACGACCGCGATCGAGGATCT
GAAGGGCGACATCACGATCACCCCGCTGCCGGCGATGGACGTCATCAAGGATCTGGTCCCCGACTTTACCCATTTCTACG
CCCAATATGCGTCGATCGAGCCGTGGCTGAAGACCAAGACGACGACGCCGAGCGGCAAGGAGCGGCTGCAATCGCCCGCC
GAGCGCGAAAAACTCGACGGGCTGTACGAGTGTATCCTGTGCGCCTGCTGCTCGACCAGCTGCCCGAGCTATTGGTGGAA
CAGCGACAAGTTCCTCGGCCCCGCGATCCTGCTCCAGGCCTATCGCTGGCTTGCCGACAGCCGCGACGAGATGACCGGCG
AGCGGCTCGACGAACTCGAAGACCCGTTCCGCCTCTATCGCTGCCACACGATCATGAACTGCGCCAATGCGTGCCCGAAG
GGGCTGAGCCCCGCGCGCGCGATCGCGGAGATCAAGAAGCTGGAGGCCGAGCGGCAGGTGTGA

Upstream 100 bases:

>100_bases
CGCCGCCAGCGGCTTTCGCGAATTGCCGGCGCATCACCCCCCTTGTCGCCGCCGCCAATCGGGTCTAGTCGGACCCGCGA
CTGCATCATGGGAGCCCGAC

Downstream 100 bases:

>100_bases
ACGACGGGATCGAGGAACCGAAGCGCCGCGATCATTTCAGCGCCGCGGAGCTGGACGGCGGCTGGATCAGCTGGGATCTG
AAAGACGCGACGCGCTTCAA

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MAEFRLPKNSRPQKGGKVHKAEGATHVKRFKVYRYDPDKGQNPHFDTFEIDTEKCGPMVLDALIKMKSEQDSTLTFRRSC
REGICGSCSMNMNGKNGLACTTAIEDLKGDITITPLPAMDVIKDLVPDFTHFYAQYASIEPWLKTKTTTPSGKERLQSPA
EREKLDGLYECILCACCSTSCPSYWWNSDKFLGPAILLQAYRWLADSRDEMTGERLDELEDPFRLYRCHTIMNCANACPK
GLSPARAIAEIKKLEAERQV

Sequences:

>Translated_260_residues
MAEFRLPKNSRPQKGGKVHKAEGATHVKRFKVYRYDPDKGQNPHFDTFEIDTEKCGPMVLDALIKMKSEQDSTLTFRRSC
REGICGSCSMNMNGKNGLACTTAIEDLKGDITITPLPAMDVIKDLVPDFTHFYAQYASIEPWLKTKTTTPSGKERLQSPA
EREKLDGLYECILCACCSTSCPSYWWNSDKFLGPAILLQAYRWLADSRDEMTGERLDELEDPFRLYRCHTIMNCANACPK
GLSPARAIAEIKKLEAERQV
>Mature_259_residues
AEFRLPKNSRPQKGGKVHKAEGATHVKRFKVYRYDPDKGQNPHFDTFEIDTEKCGPMVLDALIKMKSEQDSTLTFRRSCR
EGICGSCSMNMNGKNGLACTTAIEDLKGDITITPLPAMDVIKDLVPDFTHFYAQYASIEPWLKTKTTTPSGKERLQSPAE
REKLDGLYECILCACCSTSCPSYWWNSDKFLGPAILLQAYRWLADSRDEMTGERLDELEDPFRLYRCHTIMNCANACPKG
LSPARAIAEIKKLEAERQV

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=244, Percent_Identity=67.6229508196721, Blast_Score=346, Evalue=1e-95,
Organism=Escherichia coli, GI1786943, Length=234, Percent_Identity=56.8376068376068, Blast_Score=276, Evalue=1e-75,
Organism=Escherichia coli, GI1790596, Length=224, Percent_Identity=33.0357142857143, Blast_Score=136, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17533915, Length=231, Percent_Identity=60.1731601731602, Blast_Score=305, Evalue=2e-83,
Organism=Saccharomyces cerevisiae, GI6322987, Length=230, Percent_Identity=61.304347826087, Blast_Score=306, Evalue=3e-84,
Organism=Drosophila melanogaster, GI17137106, Length=234, Percent_Identity=61.5384615384615, Blast_Score=322, Evalue=1e-88,
Organism=Drosophila melanogaster, GI24643156, Length=232, Percent_Identity=60.3448275862069, Blast_Score=302, Evalue=2e-82,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29390; Mature: 29259

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEFRLPKNSRPQKGGKVHKAEGATHVKRFKVYRYDPDKGQNPHFDTFEIDTEKCGPMVL
CCCCCCCCCCCCCCCCCEECCCCCHHHHHEEEEEECCCCCCCCCCCCEEECHHHCCHHHH
DALIKMKSEQDSTLTFRRSCREGICGSCSMNMNGKNGLACTTAIEDLKGDITITPLPAMD
HHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHCCCEEECCCCHHH
VIKDLVPDFTHFYAQYASIEPWLKTKTTTPSGKERLQSPAEREKLDGLYECILCACCSTS
HHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
CPSYWWNSDKFLGPAILLQAYRWLADSRDEMTGERLDELEDPFRLYRCHTIMNCANACPK
CCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLSPARAIAEIKKLEAERQV
CCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEFRLPKNSRPQKGGKVHKAEGATHVKRFKVYRYDPDKGQNPHFDTFEIDTEKCGPMVL
CCCCCCCCCCCCCCCCEECCCCCHHHHHEEEEEECCCCCCCCCCCCEEECHHHCCHHHH
DALIKMKSEQDSTLTFRRSCREGICGSCSMNMNGKNGLACTTAIEDLKGDITITPLPAMD
HHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHCCCEEECCCCHHH
VIKDLVPDFTHFYAQYASIEPWLKTKTTTPSGKERLQSPAEREKLDGLYECILCACCSTS
HHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
CPSYWWNSDKFLGPAILLQAYRWLADSRDEMTGERLDELEDPFRLYRCHTIMNCANACPK
CCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLSPARAIAEIKKLEAERQV
CCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA