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The map label for this gene is sucD [H]

Identifier: 103487710

GI number: 103487710

Start: 2342333

End: 2343223

Strand: Reverse

Name: sucD [H]

Synonym: Sala_2229

Alternate gene names: 103487710

Gene position: 2343223-2342333 (Counterclockwise)

Preceding gene: 103487711

Following gene: 103487709

Centisome position: 70.05

GC content: 65.32

Gene sequence:

>891_bases
ATGAGCATTCTCATCGACAAGAATACCAAGGTCATCACGCAAGGGATGACCGGTGCCACCGGCACCTTCCACACCGAACA
GGCGCTCGCCTATGGCACGAAGATGGTCGGCGGCGTGACGCCGGGCAAGGGCGGCACGACACACATCGGCCTGCCGATGT
TCAATACCGTCGAAGAAGCGAAACATGCGACCGGCGCGACCGCGTCGGTCATCTATGTGCCGCCGCCGTTCGCGGCCGAT
TCGATCCTCGAGGCGATCGACGCCGAGGTCGAGCTGATCGTCTGCATCACCGAGGGCATTCCGGTGCTCGACATGGTCAA
GGTGAAGCGCGCGCTGTCGGGCTCGAAATCGCGGCTGATCGGCCCGAACTGCCCCGGCGTGCTGACGCCGGAAGAGTGCA
AGATCGGCATCATGCCCGGCAACATCTTCAAAAAGGGCAGCGTCGGCGTCGTCTCGCGCTCGGGCACGCTGACCTATGAA
GCGGTGTTCCAGACCTCGAACGTCGGGCTGGGCCAGACGACCGCGGTCGGCATCGGCGGCGACCCGGTCAACGGCACCAA
CTTCATCGACGTGCTCGAACTCTTCCTCGCCGATGACGCGACGAAGAGCATCATCATGATCGGCGAAATCGGCGGTGATG
CCGAGGAGCAGGCGGCGCAGTTCCTGATCGACGAAGCCAAGCGCGGCCGCAAGAAGCCGATGGCCGGCTTCATCGCGGGC
CGCACCGCACCGCCGGGCCGCCGCATGGGCCATGCCGGCGCGATCGTGTCGGGCGGCAAGGGCGACGCCGAAAGCAAGAT
TGCGGCGATGGAAGCCGCGGGCATCAAGGTGTCGGCGAGCCCGTCGGAACTCGGCACGACGCTCGCCGAAGTGCTGAAGG
AACGCGTCTGA

Upstream 100 bases:

>100_bases
GGCCCGTCGCCCGCGCTCGACAGGTCGGACGGGCCGGTGAATCAAATATCTGGAGATGGGCCCCTGCCTTCGCAGGGGCA
CGAGAAACGGAACGAAATCC

Downstream 100 bases:

>100_bases
ACTGACGGCCCGCCGACGCCCTTTGTCGGCGGGTCTCCGCTCCCCATATAAAATCCACTCCTTACCCCCCCCCCCCGTGG
AAAAACAAATGAACCTCGAA

Product: succinyl-CoA synthetase, alpha subunit

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSILIDKNTKVITQGMTGATGTFHTEQALAYGTKMVGGVTPGKGGTTHIGLPMFNTVEEAKHATGATASVIYVPPPFAAD
SILEAIDAEVELIVCITEGIPVLDMVKVKRALSGSKSRLIGPNCPGVLTPEECKIGIMPGNIFKKGSVGVVSRSGTLTYE
AVFQTSNVGLGQTTAVGIGGDPVNGTNFIDVLELFLADDATKSIIMIGEIGGDAEEQAAQFLIDEAKRGRKKPMAGFIAG
RTAPPGRRMGHAGAIVSGGKGDAESKIAAMEAAGIKVSASPSELGTTLAEVLKERV

Sequences:

>Translated_296_residues
MSILIDKNTKVITQGMTGATGTFHTEQALAYGTKMVGGVTPGKGGTTHIGLPMFNTVEEAKHATGATASVIYVPPPFAAD
SILEAIDAEVELIVCITEGIPVLDMVKVKRALSGSKSRLIGPNCPGVLTPEECKIGIMPGNIFKKGSVGVVSRSGTLTYE
AVFQTSNVGLGQTTAVGIGGDPVNGTNFIDVLELFLADDATKSIIMIGEIGGDAEEQAAQFLIDEAKRGRKKPMAGFIAG
RTAPPGRRMGHAGAIVSGGKGDAESKIAAMEAAGIKVSASPSELGTTLAEVLKERV
>Mature_295_residues
SILIDKNTKVITQGMTGATGTFHTEQALAYGTKMVGGVTPGKGGTTHIGLPMFNTVEEAKHATGATASVIYVPPPFAADS
ILEAIDAEVELIVCITEGIPVLDMVKVKRALSGSKSRLIGPNCPGVLTPEECKIGIMPGNIFKKGSVGVVSRSGTLTYEA
VFQTSNVGLGQTTAVGIGGDPVNGTNFIDVLELFLADDATKSIIMIGEIGGDAEEQAAQFLIDEAKRGRKKPMAGFIAGR
TAPPGRRMGHAGAIVSGGKGDAESKIAAMEAAGIKVSASPSELGTTLAEVLKERV

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=294, Percent_Identity=67.3469387755102, Blast_Score=350, Evalue=6e-97,
Organism=Homo sapiens, GI38569423, Length=266, Percent_Identity=29.3233082706767, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI38569421, Length=266, Percent_Identity=29.3233082706767, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1786949, Length=293, Percent_Identity=67.5767918088737, Blast_Score=394, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17550194, Length=289, Percent_Identity=61.9377162629758, Blast_Score=347, Evalue=3e-96,
Organism=Caenorhabditis elegans, GI17553126, Length=292, Percent_Identity=62.3287671232877, Blast_Score=347, Evalue=5e-96,
Organism=Caenorhabditis elegans, GI17557344, Length=263, Percent_Identity=27.7566539923954, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17551266, Length=269, Percent_Identity=28.2527881040892, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324716, Length=295, Percent_Identity=53.5593220338983, Blast_Score=293, Evalue=3e-80,
Organism=Drosophila melanogaster, GI21356559, Length=290, Percent_Identity=59.3103448275862, Blast_Score=360, Evalue=1e-100,
Organism=Drosophila melanogaster, GI28574296, Length=294, Percent_Identity=63.6054421768708, Blast_Score=342, Evalue=2e-94,
Organism=Drosophila melanogaster, GI281363477, Length=268, Percent_Identity=28.3582089552239, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI281363475, Length=268, Percent_Identity=28.3582089552239, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281363473, Length=268, Percent_Identity=28.3582089552239, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30438; Mature: 30307

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILIDKNTKVITQGMTGATGTFHTEQALAYGTKMVGGVTPGKGGTTHIGLPMFNTVEEA
CEEEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHH
KHATGATASVIYVPPPFAADSILEAIDAEVELIVCITEGIPVLDMVKVKRALSGSKSRLI
HHCCCCCEEEEEECCCCCHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCC
GPNCPGVLTPEECKIGIMPGNIFKKGSVGVVSRSGTLTYEAVFQTSNVGLGQTTAVGIGG
CCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCEEEEEEEEECCCCCCCEEEEECCC
DPVNGTNFIDVLELFLADDATKSIIMIGEIGGDAEEQAAQFLIDEAKRGRKKPMAGFIAG
CCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEC
RTAPPGRRMGHAGAIVSGGKGDAESKIAAMEAAGIKVSASPSELGTTLAEVLKERV
CCCCCCCCCCCCCCEEECCCCCCHHHHHEEHHCCEEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SILIDKNTKVITQGMTGATGTFHTEQALAYGTKMVGGVTPGKGGTTHIGLPMFNTVEEA
EEEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHH
KHATGATASVIYVPPPFAADSILEAIDAEVELIVCITEGIPVLDMVKVKRALSGSKSRLI
HHCCCCCEEEEEECCCCCHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCC
GPNCPGVLTPEECKIGIMPGNIFKKGSVGVVSRSGTLTYEAVFQTSNVGLGQTTAVGIGG
CCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCEEEEEEEEECCCCCCCEEEEECCC
DPVNGTNFIDVLELFLADDATKSIIMIGEIGGDAEEQAAQFLIDEAKRGRKKPMAGFIAG
CCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEC
RTAPPGRRMGHAGAIVSGGKGDAESKIAAMEAAGIKVSASPSELGTTLAEVLKERV
CCCCCCCCCCCCCCEEECCCCCCHHHHHEEHHCCEEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]