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The map label for this gene is engA [H]

Identifier: 103487684

GI number: 103487684

Start: 2314827

End: 2316197

Strand: Reverse

Name: engA [H]

Synonym: Sala_2203

Alternate gene names: 103487684

Gene position: 2316197-2314827 (Counterclockwise)

Preceding gene: 103487685

Following gene: 103487683

Centisome position: 69.24

GC content: 67.25

Gene sequence:

>1371_bases
ATGTCGCGACACGCGACGATCGCCATTGTCGGCCGGCCCAATGTCGGCAAATCGACGCTGTTCAACCGGCTCGTCGGCAA
GCGGCTTGCGCTGGTCGACGACCAGCCGGGGGTGACGCGCGACCGGCGCGAGGGCGACGGCAAGCTGCTCGGCCTCGAGT
TTCGCATCGTCGATACGGCGGGATTCGAGGATCAGGATGCAGCGACCCTGCCCGGTCGGATGCGCGCGCAGACCGAAAAG
GCGGTGCGCGAGGCCGACGCCGCGCTGTTCCTGATCGACGCGCGCGCCGGGGTGACGCCGCTCGACGAGGAAATCGCCCG
CTGGCTGCGCAGCGAGGATACGCCGGTGATCCTGTGCGCGAACAAGGCGGAAGGCAAGCAGGGCGAGGCAGGGTTGATGG
AGGCCTACAGCCTCGGCTTCGAGACGGTATTCGCGCTCAGCGCCGAACATGGCGAGGGTCTGGTCGACCTGTTCGACGCG
CTGCGCCCGATCGTCGAGCCCTTCATGGACGCCGAGACAGCGGCGGTCGACGAAGCCGATGAAGAGGCCGCGGGTCCGAT
GAAGCTCGCGATCGTCGGTCGTCCCAACGCCGGCAAATCGACGCTGATCAACCGGATGATCGGCGAGGACCGGCTCATCA
CCGGGCCCGAGGCGGGGATCACGCGCGATTCGATCCGCGTCGACTGGCGCTGGGAAAAGGATGGCGAGGTCCACGAGATC
CAGCTGTTCGACACCGCCGGGATGCGCAAGCGCGCGAAGGTGCAGGACAAGCTGGAGAAGCTATCGGTCGCCGACGCGCT
CCACGCGGTCGATTTCGCCGAAGTCGTCGTGCTGCTGCTCGACGCGACCAAGGGGCTGGAAGCGCAGGATCTGCGCATCG
CCGACCGGGTGCTGCAGGAAGGGCGCGCGCTGATCGTTGCGCTCAACAAATGGGACATTGCCGAAGATCCCTCGTCGCTG
TTCAACGGGGTGCGCGCGGCGCTCGACGACGGGCTCAGCCAGGTGAAGGGCGTGCCCGTGCTCAGCATTTCGGGCGCGAC
GGGCAAGGGGATCGACACGCTCGTCCGCGTCGCCTTCGAACAGCGCGCGATCTGGACGAACCGCGTTTCGACCGCGAAGC
TCAACCGCTGGTTCGAGGCGGCGGTGACCGCGAATCCGCCGCCGGCGCCGGGGGGCAAGCGGATCAAGCTGCGCTATATC
ACGCAGGCGCGCACGCGCCCGCCGACCTTCGTGGTGTTCGGATCGCGCACCGACGCGCTGCCCGGAAGCTATGAACGCTA
TCTCGTCAACGGGATGCGCAAGGAGCTGGGGTTCCAGGGCGTTCCGGTGCGGCTCAATTTCCGCAACGCGCGCAATCCCT
ATGATGAATGA

Upstream 100 bases:

>100_bases
TCGTCGCGAACAACATCCTCTACATCCTCGCGGACGACGGGACGATCACCGCCTGGCGCTAGGACAGACGAATAGGGCTG
GCCCTATTGGAGGAAAATGA

Downstream 100 bases:

>100_bases
GGTGATGGCGCGGCTGGTCGACGCGCGCGGGATGCGCTGTCCCTGGCCCGCGCTGCGGCTTGCGCGCGCGATGCGTGAGG
CGGAGGCGGTGCTGCTGGTC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MSRHATIAIVGRPNVGKSTLFNRLVGKRLALVDDQPGVTRDRREGDGKLLGLEFRIVDTAGFEDQDAATLPGRMRAQTEK
AVREADAALFLIDARAGVTPLDEEIARWLRSEDTPVILCANKAEGKQGEAGLMEAYSLGFETVFALSAEHGEGLVDLFDA
LRPIVEPFMDAETAAVDEADEEAAGPMKLAIVGRPNAGKSTLINRMIGEDRLITGPEAGITRDSIRVDWRWEKDGEVHEI
QLFDTAGMRKRAKVQDKLEKLSVADALHAVDFAEVVVLLLDATKGLEAQDLRIADRVLQEGRALIVALNKWDIAEDPSSL
FNGVRAALDDGLSQVKGVPVLSISGATGKGIDTLVRVAFEQRAIWTNRVSTAKLNRWFEAAVTANPPPAPGGKRIKLRYI
TQARTRPPTFVVFGSRTDALPGSYERYLVNGMRKELGFQGVPVRLNFRNARNPYDE

Sequences:

>Translated_456_residues
MSRHATIAIVGRPNVGKSTLFNRLVGKRLALVDDQPGVTRDRREGDGKLLGLEFRIVDTAGFEDQDAATLPGRMRAQTEK
AVREADAALFLIDARAGVTPLDEEIARWLRSEDTPVILCANKAEGKQGEAGLMEAYSLGFETVFALSAEHGEGLVDLFDA
LRPIVEPFMDAETAAVDEADEEAAGPMKLAIVGRPNAGKSTLINRMIGEDRLITGPEAGITRDSIRVDWRWEKDGEVHEI
QLFDTAGMRKRAKVQDKLEKLSVADALHAVDFAEVVVLLLDATKGLEAQDLRIADRVLQEGRALIVALNKWDIAEDPSSL
FNGVRAALDDGLSQVKGVPVLSISGATGKGIDTLVRVAFEQRAIWTNRVSTAKLNRWFEAAVTANPPPAPGGKRIKLRYI
TQARTRPPTFVVFGSRTDALPGSYERYLVNGMRKELGFQGVPVRLNFRNARNPYDE
>Mature_455_residues
SRHATIAIVGRPNVGKSTLFNRLVGKRLALVDDQPGVTRDRREGDGKLLGLEFRIVDTAGFEDQDAATLPGRMRAQTEKA
VREADAALFLIDARAGVTPLDEEIARWLRSEDTPVILCANKAEGKQGEAGLMEAYSLGFETVFALSAEHGEGLVDLFDAL
RPIVEPFMDAETAAVDEADEEAAGPMKLAIVGRPNAGKSTLINRMIGEDRLITGPEAGITRDSIRVDWRWEKDGEVHEIQ
LFDTAGMRKRAKVQDKLEKLSVADALHAVDFAEVVVLLLDATKGLEAQDLRIADRVLQEGRALIVALNKWDIAEDPSSLF
NGVRAALDDGLSQVKGVPVLSISGATGKGIDTLVRVAFEQRAIWTNRVSTAKLNRWFEAAVTANPPPAPGGKRIKLRYIT
QARTRPPTFVVFGSRTDALPGSYERYLVNGMRKELGFQGVPVRLNFRNARNPYDE

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=472, Percent_Identity=40.4661016949153, Blast_Score=325, Evalue=5e-90,
Organism=Escherichia coli, GI1788919, Length=150, Percent_Identity=32, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI2367268, Length=173, Percent_Identity=34.1040462427746, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49931; Mature: 49800

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRHATIAIVGRPNVGKSTLFNRLVGKRLALVDDQPGVTRDRREGDGKLLGLEFRIVDTA
CCCCEEEEEEECCCCCHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCEEEEEEEEEECC
GFEDQDAATLPGRMRAQTEKAVREADAALFLIDARAGVTPLDEEIARWLRSEDTPVILCA
CCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEC
NKAEGKQGEAGLMEAYSLGFETVFALSAEHGEGLVDLFDALRPIVEPFMDAETAAVDEAD
CCCCCCCCCCHHHHHHHCCHHEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCC
EEAAGPMKLAIVGRPNAGKSTLINRMIGEDRLITGPEAGITRDSIRVDWRWEKDGEVHEI
HHCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEECCCCCCCCCCEEEEEEECCCCCEEEE
QLFDTAGMRKRAKVQDKLEKLSVADALHAVDFAEVVVLLLDATKGLEAQDLRIADRVLQE
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHC
GRALIVALNKWDIAEDPSSLFNGVRAALDDGLSQVKGVPVLSISGATGKGIDTLVRVAFE
CCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHH
QRAIWTNRVSTAKLNRWFEAAVTANPPPAPGGKRIKLRYITQARTRPPTFVVFGSRTDAL
HHHHHHCCCCHHHHHHHHHEEEECCCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCC
PGSYERYLVNGMRKELGFQGVPVRLNFRNARNPYDE
CCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure 
SRHATIAIVGRPNVGKSTLFNRLVGKRLALVDDQPGVTRDRREGDGKLLGLEFRIVDTA
CCCEEEEEEECCCCCHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCEEEEEEEEEECC
GFEDQDAATLPGRMRAQTEKAVREADAALFLIDARAGVTPLDEEIARWLRSEDTPVILCA
CCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEC
NKAEGKQGEAGLMEAYSLGFETVFALSAEHGEGLVDLFDALRPIVEPFMDAETAAVDEAD
CCCCCCCCCCHHHHHHHCCHHEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCC
EEAAGPMKLAIVGRPNAGKSTLINRMIGEDRLITGPEAGITRDSIRVDWRWEKDGEVHEI
HHCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEECCCCCCCCCCEEEEEEECCCCCEEEE
QLFDTAGMRKRAKVQDKLEKLSVADALHAVDFAEVVVLLLDATKGLEAQDLRIADRVLQE
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHC
GRALIVALNKWDIAEDPSSLFNGVRAALDDGLSQVKGVPVLSISGATGKGIDTLVRVAFE
CCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHH
QRAIWTNRVSTAKLNRWFEAAVTANPPPAPGGKRIKLRYITQARTRPPTFVVFGSRTDAL
HHHHHHCCCCHHHHHHHHHEEEECCCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCC
PGSYERYLVNGMRKELGFQGVPVRLNFRNARNPYDE
CCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA