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The map label for this gene is coaD

Identifier: 103487674

GI number: 103487674

Start: 2305319

End: 2305825

Strand: Reverse

Name: coaD

Synonym: Sala_2193

Alternate gene names: 103487674

Gene position: 2305825-2305319 (Counterclockwise)

Preceding gene: 103487675

Following gene: 103487673

Centisome position: 68.93

GC content: 60.95

Gene sequence:

>507_bases
ATGCGGGTGGGGGTTTATCCGGGGACGTTCGATCCGATCACGCTTGGCCATATGGACATCATCCGGCGCGGCGCGAAGCT
CGTCGACCGGCTGGTGATCGGGGTGACAACCAATATCACCAAGTCGCCGCTGTTCGACGACGACGAACGCATCGCGATGG
TGAAGCGCGAGGTCGCCGCGATCGAAGGCGACATTCAGGTCGTTGGGTTCAATTCGCTGCTGATGGATTTTGCCCAGCGC
GAAGGCGCGACGGTCATCGTCCGCGGGCTGCGCGCGGTCGCCGATTTCGAATATGAATATCAGATGGCCGGCATGAACCA
GCAACTCAACGACCGCATCGAAACCGTCTTTCTGATGGCCGATGTCGGCTTGCAGCCGATCGCGTCGCGATTGGTCAAGG
AAATCGCGATCTTCGGCGGCGAGATCCACAAATTCGTGACACCGGCCGTCTGCAAGGCGGTCATCGCGCGCATTGCCGAA
CGGGGATTGCGCCAGGGCGAGCGTTGA

Upstream 100 bases:

>100_bases
CGCTGCTCGTCGAACAGGCGATCGCTCATCTCGGCGGCTTCGGCGACGAAGCCGCGCTGCTCCGCGCGATCGCGCGCTAT
GTCGTGGAAAGGGACCGGTA

Downstream 100 bases:

>100_bases
GGCCAATCATTGAGCGTTCATATTTTTCCCGCTAGGGGACGCCCGACGGGGCGCAATTCCGATTATCCAAGAGGCCGATC
CAGCATGACATTTTTTTTCC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MRVGVYPGTFDPITLGHMDIIRRGAKLVDRLVIGVTTNITKSPLFDDDERIAMVKREVAAIEGDIQVVGFNSLLMDFAQR
EGATVIVRGLRAVADFEYEYQMAGMNQQLNDRIETVFLMADVGLQPIASRLVKEIAIFGGEIHKFVTPAVCKAVIARIAE
RGLRQGER

Sequences:

>Translated_168_residues
MRVGVYPGTFDPITLGHMDIIRRGAKLVDRLVIGVTTNITKSPLFDDDERIAMVKREVAAIEGDIQVVGFNSLLMDFAQR
EGATVIVRGLRAVADFEYEYQMAGMNQQLNDRIETVFLMADVGLQPIASRLVKEIAIFGGEIHKFVTPAVCKAVIARIAE
RGLRQGER
>Mature_168_residues
MRVGVYPGTFDPITLGHMDIIRRGAKLVDRLVIGVTTNITKSPLFDDDERIAMVKREVAAIEGDIQVVGFNSLLMDFAQR
EGATVIVRGLRAVADFEYEYQMAGMNQQLNDRIETVFLMADVGLQPIASRLVKEIAIFGGEIHKFVTPAVCKAVIARIAE
RGLRQGER

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=156, Percent_Identity=43.5897435897436, Blast_Score=150, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_SPHAL (Q1GR20)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_617235.1
- ProteinModelPortal:   Q1GR20
- SMR:   Q1GR20
- GeneID:   4080227
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_2193
- NMPDR:   fig|317655.9.peg.2122
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   SALA317655:SALA_2193-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18634; Mature: 18634

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVGVYPGTFDPITLGHMDIIRRGAKLVDRLVIGVTTNITKSPLFDDDERIAMVKREVAA
CEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
IEGDIQVVGFNSLLMDFAQREGATVIVRGLRAVADFEYEYQMAGMNQQLNDRIETVFLMA
HCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHH
DVGLQPIASRLVKEIAIFGGEIHKFVTPAVCKAVIARIAERGLRQGER
HCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRVGVYPGTFDPITLGHMDIIRRGAKLVDRLVIGVTTNITKSPLFDDDERIAMVKREVAA
CEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
IEGDIQVVGFNSLLMDFAQREGATVIVRGLRAVADFEYEYQMAGMNQQLNDRIETVFLMA
HCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHH
DVGLQPIASRLVKEIAIFGGEIHKFVTPAVCKAVIARIAERGLRQGER
HCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA