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The map label for this gene is mmgC [H]

Identifier: 103487343

GI number: 103487343

Start: 1953318

End: 1954613

Strand: Reverse

Name: mmgC [H]

Synonym: Sala_1859

Alternate gene names: 103487343

Gene position: 1954613-1953318 (Counterclockwise)

Preceding gene: 103487344

Following gene: 103487342

Centisome position: 58.43

GC content: 63.43

Gene sequence:

>1296_bases
ATGGATTTTGCGGTTCCGGCCGATTTGCAGGCCTATCTGGACGAACTCGACGCCTTCATCGAAGCGGAGATCAAGCCGCT
CGAAGAAGCCGACGACAATATCCGCTTTTTCGACCATCGCCGCGAACATAGCCGCACCGACTGGGACAATCAGGGGCTGC
CGCGCCATGAGTGGGAAGCGCTGCTCAAGGAGGCGACGCGCCGCGCCGACGCCGCGGGCCACTGGCGCTTTTCGGCGCCG
AAGAAATATGGCGGCAAGGACGGATCAAACCTGTGGATGGCGGTGATCCGCGAACATTTTGCCGCCAAGGGGCTGGGGCT
GCACAATGATCTGCAGAACGAGCACAGCATCGTCGGCAATTTCCCCTTCGTCGAAATGTTCGAGCAGTTCGCGACGAGCG
AGGAACAGAAGGCGGAGTTCATCCTCGGCGGCTTCGAGGGTCGGCGTCGCACCGCCTTTGGCCTGACCGAGCCGGACCAT
GGCAGCGACGCGACGCATATGGAAACGCGCGCGGTGCGGCAAACGCGCGACGGCGTCGACGGCTGGCTGATCAACGGCCG
CAAGATGTGGATCACCGGGATGCACGTCGCGACGCACTGCGCGACCTTTTGCCGGACGAGCGGCGCCGACGGCGATGCGA
AGGGGATCACCTGCTTGCTGGTGCCGACGGGCACGCCCGGCATGACGGTCGATGAATATATGTGGACGTTCAACATGCCC
ACCGATCATCCCCGCATGACCTTTGCCGACGTGTGGGTGCCCGACAGCGCGCGGCTTGGCCCGGTGGACGGCGGGCTGTC
GATCGCGCAGAGCTTCGTCCACCAGAACCGCATTCGTCAGGCCGCAAGCTCGCTCGGCGCCGCGGTCTACTGCATCGAAG
AAAGCGTCAAATATGCGCGGGAACGCAAGCCCTTCGGCGAAGCGCTCGCCAGAAATCAAGCGATCCAGTTCCCGCTCGTC
GAGCTGGCGACGCAGGCCGAAATGCTGCGGCTGCTGATCCGCAAAACCGCGTGGGACATGGACAATACGCCGCACAAGGA
GATCGAGCGCACGCTGTCCGACAAGGTCAGCATGTGCAATTACTGGGCGAACCGCCTCGTCTGCGAAGCCGCCGACCGCG
CGATGCAGGTCCATGGCGGCATCGGCTATTCGCGGCACAAGCCCTTCGAGCATATTTATCGCCACCATCGCCGTTATCGC
ATCACCGAAGGCGCCGAAGAGATCCAGATGCGCAAGGTCGCGGCCTATCTCTTCGGCTATCTCGGCCCGCGCCGCGAAAC
GCTGGGGCGGATCTGA

Upstream 100 bases:

>100_bases
CCGCGCGGTGCTCGACAAATGCGCGGTCGATAGTCCGAAATATGCCGCGCTCGCGGCGGCGCGCGCCGAATGGCGCCAAT
AAGCGACTAGGGAGAGAGAC

Downstream 100 bases:

>100_bases
CCCTAAGTAAATGAGCCGACGCGGCTTGTCCGATCCTGTCAGGGGCGGTCGCAAAAGGCGCGCCATGCGGCAATGAAGAT
GGTTGCCGCACGAATCCCCG

Product: acyl-CoA dehydrogenase-like protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MDFAVPADLQAYLDELDAFIEAEIKPLEEADDNIRFFDHRREHSRTDWDNQGLPRHEWEALLKEATRRADAAGHWRFSAP
KKYGGKDGSNLWMAVIREHFAAKGLGLHNDLQNEHSIVGNFPFVEMFEQFATSEEQKAEFILGGFEGRRRTAFGLTEPDH
GSDATHMETRAVRQTRDGVDGWLINGRKMWITGMHVATHCATFCRTSGADGDAKGITCLLVPTGTPGMTVDEYMWTFNMP
TDHPRMTFADVWVPDSARLGPVDGGLSIAQSFVHQNRIRQAASSLGAAVYCIEESVKYARERKPFGEALARNQAIQFPLV
ELATQAEMLRLLIRKTAWDMDNTPHKEIERTLSDKVSMCNYWANRLVCEAADRAMQVHGGIGYSRHKPFEHIYRHHRRYR
ITEGAEEIQMRKVAAYLFGYLGPRRETLGRI

Sequences:

>Translated_431_residues
MDFAVPADLQAYLDELDAFIEAEIKPLEEADDNIRFFDHRREHSRTDWDNQGLPRHEWEALLKEATRRADAAGHWRFSAP
KKYGGKDGSNLWMAVIREHFAAKGLGLHNDLQNEHSIVGNFPFVEMFEQFATSEEQKAEFILGGFEGRRRTAFGLTEPDH
GSDATHMETRAVRQTRDGVDGWLINGRKMWITGMHVATHCATFCRTSGADGDAKGITCLLVPTGTPGMTVDEYMWTFNMP
TDHPRMTFADVWVPDSARLGPVDGGLSIAQSFVHQNRIRQAASSLGAAVYCIEESVKYARERKPFGEALARNQAIQFPLV
ELATQAEMLRLLIRKTAWDMDNTPHKEIERTLSDKVSMCNYWANRLVCEAADRAMQVHGGIGYSRHKPFEHIYRHHRRYR
ITEGAEEIQMRKVAAYLFGYLGPRRETLGRI
>Mature_431_residues
MDFAVPADLQAYLDELDAFIEAEIKPLEEADDNIRFFDHRREHSRTDWDNQGLPRHEWEALLKEATRRADAAGHWRFSAP
KKYGGKDGSNLWMAVIREHFAAKGLGLHNDLQNEHSIVGNFPFVEMFEQFATSEEQKAEFILGGFEGRRRTAFGLTEPDH
GSDATHMETRAVRQTRDGVDGWLINGRKMWITGMHVATHCATFCRTSGADGDAKGITCLLVPTGTPGMTVDEYMWTFNMP
TDHPRMTFADVWVPDSARLGPVDGGLSIAQSFVHQNRIRQAASSLGAAVYCIEESVKYARERKPFGEALARNQAIQFPLV
ELATQAEMLRLLIRKTAWDMDNTPHKEIERTLSDKVSMCNYWANRLVCEAADRAMQVHGGIGYSRHKPFEHIYRHHRRYR
ITEGAEEIQMRKVAAYLFGYLGPRRETLGRI

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=354, Percent_Identity=29.3785310734463, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI187960098, Length=356, Percent_Identity=29.7752808988764, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI4557231, Length=356, Percent_Identity=29.7752808988764, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI4501859, Length=342, Percent_Identity=28.6549707602339, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI7656849, Length=287, Percent_Identity=31.7073170731707, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI21361497, Length=412, Percent_Identity=25.7281553398058, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI4501857, Length=390, Percent_Identity=26.6666666666667, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI38505218, Length=418, Percent_Identity=24.4019138755981, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI211971008, Length=367, Percent_Identity=26.158038147139, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI48976061, Length=367, Percent_Identity=26.158038147139, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI76496475, Length=412, Percent_Identity=25.2427184466019, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4557235, Length=412, Percent_Identity=25.2427184466019, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI226958414, Length=379, Percent_Identity=23.7467018469657, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI226958412, Length=352, Percent_Identity=23.8636363636364, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI7669494, Length=199, Percent_Identity=31.6582914572864, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI4503943, Length=199, Percent_Identity=31.6582914572864, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1786223, Length=258, Percent_Identity=28.2945736434109, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87081958, Length=259, Percent_Identity=26.2548262548263, Blast_Score=88, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17569725, Length=365, Percent_Identity=29.8630136986301, Blast_Score=147, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI17534899, Length=359, Percent_Identity=30.9192200557103, Blast_Score=138, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17533517, Length=373, Percent_Identity=28.686327077748, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17570075, Length=425, Percent_Identity=25.4117647058824, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17506239, Length=346, Percent_Identity=27.7456647398844, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71985184, Length=341, Percent_Identity=27.5659824046921, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17508101, Length=346, Percent_Identity=28.6127167630058, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17505929, Length=350, Percent_Identity=28.2857142857143, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17551932, Length=350, Percent_Identity=27.1428571428571, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17562446, Length=294, Percent_Identity=28.2312925170068, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI71990804, Length=268, Percent_Identity=27.9850746268657, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17538396, Length=343, Percent_Identity=25.6559766763848, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71985192, Length=301, Percent_Identity=25.5813953488372, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI32563615, Length=244, Percent_Identity=29.9180327868852, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17534353, Length=265, Percent_Identity=26.7924528301887, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24660351, Length=342, Percent_Identity=31.5789473684211, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24646207, Length=304, Percent_Identity=32.5657894736842, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24666513, Length=317, Percent_Identity=30.5993690851735, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21356377, Length=287, Percent_Identity=28.9198606271777, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21355753, Length=411, Percent_Identity=25.3041362530414, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281363737, Length=435, Percent_Identity=25.0574712643678, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19920834, Length=197, Percent_Identity=34.010152284264, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 49070; Mature: 49070

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFAVPADLQAYLDELDAFIEAEIKPLEEADDNIRFFDHRREHSRTDWDNQGLPRHEWEA
CCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHH
LLKEATRRADAAGHWRFSAPKKYGGKDGSNLWMAVIREHFAAKGLGLHNDLQNEHSIVGN
HHHHHHHHCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCEECC
FPFVEMFEQFATSEEQKAEFILGGFEGRRRTAFGLTEPDHGSDATHMETRAVRQTRDGVD
CHHHHHHHHHHCCCHHHHHHEEECCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCC
GWLINGRKMWITGMHVATHCATFCRTSGADGDAKGITCLLVPTGTPGMTVDEYMWTFNMP
EEEECCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCHHHEEEEECCC
TDHPRMTFADVWVPDSARLGPVDGGLSIAQSFVHQNRIRQAASSLGAAVYCIEESVKYAR
CCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHH
ERKPFGEALARNQAIQFPLVELATQAEMLRLLIRKTAWDMDNTPHKEIERTLSDKVSMCN
HCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
YWANRLVCEAADRAMQVHGGIGYSRHKPFEHIYRHHRRYRITEGAEEIQMRKVAAYLFGY
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCEECCCCHHHHHHHHHHHHHHHH
LGPRRETLGRI
CCCCHHHHCCC
>Mature Secondary Structure
MDFAVPADLQAYLDELDAFIEAEIKPLEEADDNIRFFDHRREHSRTDWDNQGLPRHEWEA
CCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHH
LLKEATRRADAAGHWRFSAPKKYGGKDGSNLWMAVIREHFAAKGLGLHNDLQNEHSIVGN
HHHHHHHHCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCEECC
FPFVEMFEQFATSEEQKAEFILGGFEGRRRTAFGLTEPDHGSDATHMETRAVRQTRDGVD
CHHHHHHHHHHCCCHHHHHHEEECCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCC
GWLINGRKMWITGMHVATHCATFCRTSGADGDAKGITCLLVPTGTPGMTVDEYMWTFNMP
EEEECCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCHHHEEEEECCC
TDHPRMTFADVWVPDSARLGPVDGGLSIAQSFVHQNRIRQAASSLGAAVYCIEESVKYAR
CCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHH
ERKPFGEALARNQAIQFPLVELATQAEMLRLLIRKTAWDMDNTPHKEIERTLSDKVSMCN
HCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
YWANRLVCEAADRAMQVHGGIGYSRHKPFEHIYRHHRRYRITEGAEEIQMRKVAAYLFGY
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCEECCCCHHHHHHHHHHHHHHHH
LGPRRETLGRI
CCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]