Click here to switch to the map view.

The map label for this gene is ycsN [H]

Identifier: 103487146

GI number: 103487146

Start: 1746483

End: 1747397

Strand: Reverse

Name: ycsN [H]

Synonym: Sala_1661

Alternate gene names: 103487146

Gene position: 1747397-1746483 (Counterclockwise)

Preceding gene: 103487147

Following gene: 103487145

Centisome position: 52.24

GC content: 66.67

Gene sequence:

>915_bases
ATGAGCTTGTTGCCCGTCCCGCCTGCATCGCGTCCGCTCGGAAACAGCGGCATGTCGGTTTCGTCCATCGCCTGGGGTAT
GTGGCGGTTTGCCGAGGGTGGACGCACCGTCGCCGACGCGGCCCGGCTGGTGCATGCGGCGCTCGATGCGGGAATCACCT
TGCTCGACACCGCCGATATATACGGGTTCGACGGGGCGGGGGGCTTCGGCGACGCCGAAGCGTTGCTGGGTGAGGTGCTG
GCGACCGAACCGGCGCTGCGCGATCGCATGGTGCTTGCGACGAAAGGCGGCATTCGCCCGCCGCTTCCCTATGATCAAAG
TCCCGAATATCTTGGCGAGGCGATCCATGCGTCGCTGCGGCGGCTGCGAACCGACCGGATTGATCTTTGGCAGATCCATC
GTCCCGACATTCTGGCGCATCCCCAGGAGGTCGCCCGTACGCTCGATGACGCGATAGCGGCGGGCAAGATCCGCTCGCTC
GGCGTCTCCAACTTCACCATCGCGCAGACCGACGCGCTCAATGGCTTTCTTGGCAGCAAGCTCGTCGCCACGCAGCCCGA
AATCAGTCCGCTGCGCATCGACTGTTTCGAAAATGGCGAGCTTGACCGGGCCATGGCGATCGGGCTCGTCCCGCTCGCCT
GGTCACCGCTGGGCGGCGGGCGGCTGCTCGCCCCGCAAAGCGACCGCGACAAGGCGGTCGCCGCTGCGCTGGACCGGGTA
GCCGCCGCGCAAAATGTGTCGCGCGAAATTGCCGCCTACAGCTGGCTGATGGCGCATCCAGCAGGCATCGTGCCGATTGT
CGGATCGCAGCGCGCCGAACGAATTGGGGAGGCGGCAAGCGCGCTCCGTGTCCGGTGGACGCGGTCCGAATGGTATGACG
TGCTTGTTGCCGCGCGCGGCGCCGCGTTGCCCTGA

Upstream 100 bases:

>100_bases
CGACGCGAATACTGATCGAGGGTGGCGACATCAGCCATCACCGCCTTCCCCACACCCTTGTCGAGCGCGCTTCGGTCGCG
CCACCTGCCAGGAATCCTCT

Downstream 100 bases:

>100_bases
ACCTGCGGCGCCGTCCGCCGCGCATGACAAGACCCTGCGAAACGAGGCGTCCCAGGGCATGGAGAGGAAGAGACATGACC
CAACAGCAATGCGAGATCGC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSLLPVPPASRPLGNSGMSVSSIAWGMWRFAEGGRTVADAARLVHAALDAGITLLDTADIYGFDGAGGFGDAEALLGEVL
ATEPALRDRMVLATKGGIRPPLPYDQSPEYLGEAIHASLRRLRTDRIDLWQIHRPDILAHPQEVARTLDDAIAAGKIRSL
GVSNFTIAQTDALNGFLGSKLVATQPEISPLRIDCFENGELDRAMAIGLVPLAWSPLGGGRLLAPQSDRDKAVAAALDRV
AAAQNVSREIAAYSWLMAHPAGIVPIVGSQRAERIGEAASALRVRWTRSEWYDVLVAARGAALP

Sequences:

>Translated_304_residues
MSLLPVPPASRPLGNSGMSVSSIAWGMWRFAEGGRTVADAARLVHAALDAGITLLDTADIYGFDGAGGFGDAEALLGEVL
ATEPALRDRMVLATKGGIRPPLPYDQSPEYLGEAIHASLRRLRTDRIDLWQIHRPDILAHPQEVARTLDDAIAAGKIRSL
GVSNFTIAQTDALNGFLGSKLVATQPEISPLRIDCFENGELDRAMAIGLVPLAWSPLGGGRLLAPQSDRDKAVAAALDRV
AAAQNVSREIAAYSWLMAHPAGIVPIVGSQRAERIGEAASALRVRWTRSEWYDVLVAARGAALP
>Mature_303_residues
SLLPVPPASRPLGNSGMSVSSIAWGMWRFAEGGRTVADAARLVHAALDAGITLLDTADIYGFDGAGGFGDAEALLGEVLA
TEPALRDRMVLATKGGIRPPLPYDQSPEYLGEAIHASLRRLRTDRIDLWQIHRPDILAHPQEVARTLDDAIAAGKIRSLG
VSNFTIAQTDALNGFLGSKLVATQPEISPLRIDCFENGELDRAMAIGLVPLAWSPLGGGRLLAPQSDRDKAVAAALDRVA
AAQNVSREIAAYSWLMAHPAGIVPIVGSQRAERIGEAASALRVRWTRSEWYDVLVAARGAALP

Specific function: Unknown

COG id: COG4989

COG function: function code R; Predicted oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI4504825, Length=308, Percent_Identity=23.0519480519481, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI27436969, Length=308, Percent_Identity=23.0519480519481, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI27436962, Length=219, Percent_Identity=27.3972602739726, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI27436964, Length=217, Percent_Identity=27.1889400921659, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI27436966, Length=217, Percent_Identity=27.1889400921659, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI48994888, Length=297, Percent_Identity=34.6801346801347, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI87081735, Length=316, Percent_Identity=29.1139240506329, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788081, Length=275, Percent_Identity=28, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789375, Length=304, Percent_Identity=26.6447368421053, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788070, Length=241, Percent_Identity=29.045643153527, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786400, Length=226, Percent_Identity=28.3185840707965, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319958, Length=296, Percent_Identity=25, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323998, Length=336, Percent_Identity=24.1071428571429, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24646155, Length=280, Percent_Identity=27.8571428571429, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 32349; Mature: 32218

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00062 ALDOKETO_REDUCTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLPVPPASRPLGNSGMSVSSIAWGMWRFAEGGRTVADAARLVHAALDAGITLLDTADI
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEECCCC
YGFDGAGGFGDAEALLGEVLATEPALRDRMVLATKGGIRPPLPYDQSPEYLGEAIHASLR
CCCCCCCCCCHHHHHHHHHHHCCHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
RLRTDRIDLWQIHRPDILAHPQEVARTLDDAIAAGKIRSLGVSNFTIAQTDALNGFLGSK
HHHCCCCCEEEECCCCHHCCHHHHHHHHHHHHHHCHHHHCCCCCEEEEEHHHHHHHHCCC
LVATQPEISPLRIDCFENGELDRAMAIGLVPLAWSPLGGGRLLAPQSDRDKAVAAALDRV
EEECCCCCCCEEEEEECCCCCCHHHHHEEHHHCCCCCCCCEEECCCCCCHHHHHHHHHHH
AAAQNVSREIAAYSWLMAHPAGIVPIVGSQRAERIGEAASALRVRWTRSEWYDVLVAARG
HHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHEEEECHHHHHHHHHHHCC
AALP
CCCC
>Mature Secondary Structure 
SLLPVPPASRPLGNSGMSVSSIAWGMWRFAEGGRTVADAARLVHAALDAGITLLDTADI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEECCCC
YGFDGAGGFGDAEALLGEVLATEPALRDRMVLATKGGIRPPLPYDQSPEYLGEAIHASLR
CCCCCCCCCCHHHHHHHHHHHCCHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
RLRTDRIDLWQIHRPDILAHPQEVARTLDDAIAAGKIRSLGVSNFTIAQTDALNGFLGSK
HHHCCCCCEEEECCCCHHCCHHHHHHHHHHHHHHCHHHHCCCCCEEEEEHHHHHHHHCCC
LVATQPEISPLRIDCFENGELDRAMAIGLVPLAWSPLGGGRLLAPQSDRDKAVAAALDRV
EEECCCCCCCEEEEEECCCCCCHHHHHEEHHHCCCCCCCCEEECCCCCCHHHHHHHHHHH
AAAQNVSREIAAYSWLMAHPAGIVPIVGSQRAERIGEAASALRVRWTRSEWYDVLVAARG
HHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHEEEECHHHHHHHHHHHCC
AALP
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]