Click here to switch to the map view.

The map label for this gene is bcd [H]

Identifier: 103487117

GI number: 103487117

Start: 1713547

End: 1714770

Strand: Reverse

Name: bcd [H]

Synonym: Sala_1632

Alternate gene names: 103487117

Gene position: 1714770-1713547 (Counterclockwise)

Preceding gene: 103487118

Following gene: 103487111

Centisome position: 51.26

GC content: 63.81

Gene sequence:

>1224_bases
ATGGATTTCAACGACAGCCCCGAAGAAGCCGCCTTTCGCGCCGAAGCGCGCGCCTGGCTCGCCGCCCACGCCCCGGCGCA
TGAAATCCCGCCCGGTGCGAAAATGTCGGACACCGAAGAAGCGGCGCGCGGACGGGCGTGGATTCGGGAATTATATGAAG
GTGGCTGGTCGGGCCTGACCTTTTCCAGGGAGCTTGGTGGGCGCGGGGCTTCGGGGATCGAGGCAGTGATCTTCGCCGAA
GAAGAAGGTCGCTATCACCTGCCCAAGGGACCATTTGTTTCGATCGGCACCGGCATGGCGCTGCCGGTCATCGCAAGGCA
CGGCACCGAGGAACAAAAGGCCCGATTCGTCGAACCGACGCTGAAGGGCGAGATCACCTGGTGTCAGCTTTTCTCCGAAC
CCGCGGCGGGATCGGACCTTGCCGGGCTTCGCACCAAGGCGGTTCGTGCCGACGATGGTTCGGGCGACTGGATCGTCAAC
GGCCAGAAGGTCTGGTCGAGTTGGGCGCATCTGACCGACTGGGGGATATTGGTGGTGCGAACCGACCCCGGTGTGCCGAA
GCACAAGGGGCTGACATTCTTTCTGGTCGATATGAAGACGCCGGGAATCGAAACGCGGCCGATCCGCCAGATTTCAGGGG
CCAGCGAATTCAACGAGACATTCCTGACCGACGTTCGCATTCCCGACGCCAATCGGCTGGGCGCGGAAGGCGAGGGCTGG
GCCTGTTGCATGACCGTGCTGATGGGCGAACGGCTGGGATCGGGCGCGCATCGCAGCGGGGTCGCAACGCTGCTCGATTA
TGCGGCGGCAACGCCGGACGGCCATGGCGGCACGATGCTGGACGATGGCGCGGTGCGGCAACAACTTGCCGAAGCGCTGG
CGGAAGAACAGGGGGAGCGTTTCTTTCAGGCAAGGCTGCGCACGATGGTGTCGAAGGGCGAAAATCCCGGCGCGCTCGCG
GGGATGGTCAAGCTGGCCTATGCCAGTCGATACCAGCGGACCAACGGGCTGGCGCTTGAACTGCGCGGCCTCGCCGGAAT
TGCCGGTGAGCCGGGCGATAGCGCCACCGGCGACGTCCAGTATGATTATATCTATTCGACGGTGATGCGTATTGCCGGGG
GCGCGGACGAAGTTCTCCGCAACCAGATCGCCGAACGTGTGCTCGCCATGCCCGGCGAAGTGCGGATGGACAAGGATGTG
CCGTTCGAGAAGCTCAAGGCCTAG

Upstream 100 bases:

>100_bases
ATGCTTGCGGTGCATCTCGGCAATCGGGGTTTTTGGGCAAACCGGCTGCTCGCCGCGCAGCCCGGGCGCCAGGGTCAGGC
GGCCTGAGGAGGGCAGGATA

Downstream 100 bases:

>100_bases
GTGTTTGGGCCGTAAACTCATAAACCGTCTTGAGGTTTGGCGGCCTGCGTGATTCAAGCTCTCCATTGCGATGGAGGCTC
GATGGCGCGGCGGCGATACG

Product: acyl-CoA dehydrogenase-like protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MDFNDSPEEAAFRAEARAWLAAHAPAHEIPPGAKMSDTEEAARGRAWIRELYEGGWSGLTFSRELGGRGASGIEAVIFAE
EEGRYHLPKGPFVSIGTGMALPVIARHGTEEQKARFVEPTLKGEITWCQLFSEPAAGSDLAGLRTKAVRADDGSGDWIVN
GQKVWSSWAHLTDWGILVVRTDPGVPKHKGLTFFLVDMKTPGIETRPIRQISGASEFNETFLTDVRIPDANRLGAEGEGW
ACCMTVLMGERLGSGAHRSGVATLLDYAAATPDGHGGTMLDDGAVRQQLAEALAEEQGERFFQARLRTMVSKGENPGALA
GMVKLAYASRYQRTNGLALELRGLAGIAGEPGDSATGDVQYDYIYSTVMRIAGGADEVLRNQIAERVLAMPGEVRMDKDV
PFEKLKA

Sequences:

>Translated_407_residues
MDFNDSPEEAAFRAEARAWLAAHAPAHEIPPGAKMSDTEEAARGRAWIRELYEGGWSGLTFSRELGGRGASGIEAVIFAE
EEGRYHLPKGPFVSIGTGMALPVIARHGTEEQKARFVEPTLKGEITWCQLFSEPAAGSDLAGLRTKAVRADDGSGDWIVN
GQKVWSSWAHLTDWGILVVRTDPGVPKHKGLTFFLVDMKTPGIETRPIRQISGASEFNETFLTDVRIPDANRLGAEGEGW
ACCMTVLMGERLGSGAHRSGVATLLDYAAATPDGHGGTMLDDGAVRQQLAEALAEEQGERFFQARLRTMVSKGENPGALA
GMVKLAYASRYQRTNGLALELRGLAGIAGEPGDSATGDVQYDYIYSTVMRIAGGADEVLRNQIAERVLAMPGEVRMDKDV
PFEKLKA
>Mature_407_residues
MDFNDSPEEAAFRAEARAWLAAHAPAHEIPPGAKMSDTEEAARGRAWIRELYEGGWSGLTFSRELGGRGASGIEAVIFAE
EEGRYHLPKGPFVSIGTGMALPVIARHGTEEQKARFVEPTLKGEITWCQLFSEPAAGSDLAGLRTKAVRADDGSGDWIVN
GQKVWSSWAHLTDWGILVVRTDPGVPKHKGLTFFLVDMKTPGIETRPIRQISGASEFNETFLTDVRIPDANRLGAEGEGW
ACCMTVLMGERLGSGAHRSGVATLLDYAAATPDGHGGTMLDDGAVRQQLAEALAEEQGERFFQARLRTMVSKGENPGALA
GMVKLAYASRYQRTNGLALELRGLAGIAGEPGDSATGDVQYDYIYSTVMRIAGGADEVLRNQIAERVLAMPGEVRMDKDV
PFEKLKA

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=369, Percent_Identity=28.4552845528455, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI4501857, Length=395, Percent_Identity=29.3670886075949, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI226958412, Length=241, Percent_Identity=29.045643153527, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4557233, Length=370, Percent_Identity=28.3783783783784, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI226958414, Length=227, Percent_Identity=29.9559471365639, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI7656849, Length=360, Percent_Identity=26.6666666666667, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI76496475, Length=367, Percent_Identity=26.7029972752044, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI4557235, Length=367, Percent_Identity=26.7029972752044, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI187960098, Length=248, Percent_Identity=27.0161290322581, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI4557231, Length=248, Percent_Identity=27.0161290322581, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI211971008, Length=296, Percent_Identity=25, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI38505218, Length=335, Percent_Identity=26.5671641791045, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI48976061, Length=296, Percent_Identity=25, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI21361497, Length=307, Percent_Identity=26.0586319218241, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1786223, Length=241, Percent_Identity=25.7261410788382, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17551932, Length=329, Percent_Identity=27.6595744680851, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17570075, Length=402, Percent_Identity=26.865671641791, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17505929, Length=341, Percent_Identity=28.4457478005865, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17508101, Length=283, Percent_Identity=26.1484098939929, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17534899, Length=202, Percent_Identity=31.1881188118812, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17538396, Length=255, Percent_Identity=29.0196078431373, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17569725, Length=358, Percent_Identity=25.6983240223464, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71990804, Length=264, Percent_Identity=25.7575757575758, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17506239, Length=345, Percent_Identity=25.2173913043478, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71985184, Length=353, Percent_Identity=25.2124645892351, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71985192, Length=262, Percent_Identity=26.3358778625954, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI32563615, Length=207, Percent_Identity=28.5024154589372, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71982178, Length=225, Percent_Identity=25.7777777777778, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17533517, Length=363, Percent_Identity=24.7933884297521, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24666513, Length=240, Percent_Identity=29.1666666666667, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24646207, Length=240, Percent_Identity=32.5, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI281363737, Length=275, Percent_Identity=27.2727272727273, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24660351, Length=147, Percent_Identity=32.6530612244898, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21356377, Length=217, Percent_Identity=29.0322580645161, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21355753, Length=231, Percent_Identity=29.4372294372294, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI19920834, Length=235, Percent_Identity=28.936170212766, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 43934; Mature: 43934

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFNDSPEEAAFRAEARAWLAAHAPAHEIPPGAKMSDTEEAARGRAWIRELYEGGWSGLT
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCE
FSRELGGRGASGIEAVIFAEEEGRYHLPKGPFVSIGTGMALPVIARHGTEEQKARFVEPT
EEHHHCCCCCCCCEEEEEEECCCCEECCCCCEEEECCCCHHHHHHHCCCHHHHHHHCCCH
LKGEITWCQLFSEPAAGSDLAGLRTKAVRADDGSGDWIVNGQKVWSSWAHLTDWGILVVR
HCCCEEEEEECCCCCCCCCCHHHHHHEEECCCCCCCEEECCHHHHHHHHHHCCCCEEEEE
TDPGVPKHKGLTFFLVDMKTPGIETRPIRQISGASEFNETFLTDVRIPDANRLGAEGEGW
CCCCCCCCCCCEEEEEEECCCCCCCCCHHHHCCCCHHHHHHEEEEECCCCCCCCCCCCCH
ACCMTVLMGERLGSGAHRSGVATLLDYAAATPDGHGGTMLDDGAVRQQLAEALAEEQGER
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHH
FFQARLRTMVSKGENPGALAGMVKLAYASRYQRTNGLALELRGLAGIAGEPGDSATGDVQ
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCEE
YDYIYSTVMRIAGGADEVLRNQIAERVLAMPGEVRMDKDVPFEKLKA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHCC
>Mature Secondary Structure
MDFNDSPEEAAFRAEARAWLAAHAPAHEIPPGAKMSDTEEAARGRAWIRELYEGGWSGLT
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCE
FSRELGGRGASGIEAVIFAEEEGRYHLPKGPFVSIGTGMALPVIARHGTEEQKARFVEPT
EEHHHCCCCCCCCEEEEEEECCCCEECCCCCEEEECCCCHHHHHHHCCCHHHHHHHCCCH
LKGEITWCQLFSEPAAGSDLAGLRTKAVRADDGSGDWIVNGQKVWSSWAHLTDWGILVVR
HCCCEEEEEECCCCCCCCCCHHHHHHEEECCCCCCCEEECCHHHHHHHHHHCCCCEEEEE
TDPGVPKHKGLTFFLVDMKTPGIETRPIRQISGASEFNETFLTDVRIPDANRLGAEGEGW
CCCCCCCCCCCEEEEEEECCCCCCCCCHHHHCCCCHHHHHHEEEEECCCCCCCCCCCCCH
ACCMTVLMGERLGSGAHRSGVATLLDYAAATPDGHGGTMLDDGAVRQQLAEALAEEQGER
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHH
FFQARLRTMVSKGENPGALAGMVKLAYASRYQRTNGLALELRGLAGIAGEPGDSATGDVQ
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCEE
YDYIYSTVMRIAGGADEVLRNQIAERVLAMPGEVRMDKDVPFEKLKA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]