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The map label for this gene is kup

Identifier: 103486997

GI number: 103486997

Start: 1578637

End: 1580598

Strand: Reverse

Name: kup

Synonym: Sala_1512

Alternate gene names: 103486997

Gene position: 1580598-1578637 (Counterclockwise)

Preceding gene: 103486998

Following gene: 103486996

Centisome position: 47.25

GC content: 61.93

Gene sequence:

>1962_bases
ATGACTGCTGAGTCGCAACGGGCGGCCGAGGGCGTGGCAACCGCCATCGAAGCCGCCGCCGAAACCGGCCATCACGGCCA
TGGCCCTCATGGTGACGGCAAGCTGAAGCTTGCCGTCGGTGCGGTCGGCGTCGTCTTCGGCGACATCGGTACCAGCCCGC
TCTATGCGTTCCGCGAAACCTTTGCGGGGCATCATCCGATCGAGCCCGACCGGCTGCATATCTATGGTGTGCTGAGCCTC
GTTTTCTGGTCGATGATGCTCGTCGTCACCTTCAAATATGTGATGACGATCATGCGCGCCGACAACAAGGGCGAGGGGGG
CAGCCTCGCGCTGCTCGCGCTGATCAGCCGCTCGTCGGAAGGCAAGCGCTGGACCTGGCCGATCGTCCTTCTGGGCGTGT
TTGCCACCGCCCTCTTCTATGGCGACAGCATGATTACCCCGGCGATGTCGGTGCTTTCGGCGACCGAAGGCCTGTCCTAT
GTCGACAAGGGATTCGAACCCTATATCGTGCCGATCGCCCTGGGCATACTCATCGGCCTGTTCGCGATCCAGGCGCGCGG
GACGGCGAAGGTCGGCGCGCTGTTCGGCCCGATCATGCTGCTCTATTTCCTGATGCTTGCAGGGCTTGGTATCCTGCATA
TCGGCAATAATCCGTGGATCATCGTCGAGACGCTCAACCCGGTCAACGCCCTACGATTCTTTTACCTCGACGGTTTCACG
GCCTTTATCGCGCTCGGCGCGGTCGTGCTCGCGGTGACCGGCGCGGAGGCGCTTTATGCCGACATGGGGCATTTCGGTCG
CGGGCCGATCGGCCTCTCGTGGCTGAGTTTCGTGCTGCCCGCGTTGATGCTCAACTATATGGGACAGGGCGCGATGGTCC
TTGCGGCCGAAGCGGGGCCGCGCACCGAACTGATTGCCGATCCCTTTTTCCAGATGATGCCGCAGTTTCTCGAACTGCCC
GTCGTCATCCTCGCGCTGCTTGCGACGATCATCGCCAGCCAGGCGGTGATCTCGGGCGCCTTCTCGCTGACCCAGCAGGC
GATCCAGCTCGGCTTCATGCCGCGCCTGCGGGTCGAGCACACCAGCGCGTCGGCGGCGGGGCAGATATACATTCCCATTG
TCAACTGGGGGCTGATGGTCATGGTGATTCTGCTCGTCCTCGGCTTCGGCTCGTCGAGCAACCTTGCCGCGGCCTATGGC
ATTGCCGTGACCGGGGCGATGTTCATCGATACCTGTTTGATGAGCGTCGTGCTCTTCACATTATGGAAATGGCCGGCATG
GAAGGCGCTGCCGGTGCTCGCGGTCTTCTTCATCGTCGACATCGCCTATTTCGGCGCCAACCTGATCAAGGTGCCCGACG
GCGGCTGGGTGCCGCTGGTGATCGGGCTCACCATCTTCACGCTGCTCACCACCTGGTCGCGCGGGCGCAAGCTGATGCAG
GAGGAAATGGCCGAGGGTGCGATGCCGATCCCGATTTTCGTGAAGTCGGCTGCGAACAGCGCGACGCGCGTGCCTGGCAC
CGCGGTCTTCATGACATCGAGCAGCGACGGCGTGCCGCACGCGCTGCTCCACAACCTCAAGCACAACAAGGTGCTGCACG
AGCGCATCATCCTGCTGACGATCAAGATTGCCGACGTGCCGTTCGTCCCCGAAAGCAAGCTTTGCCAGCTCGAAGATCTG
GGGCAGGGATTCCACCGGTTGGTGCTCAACTATGGTTTCATGCAGCCGATCGACGTGCCCGAGGCGCTGATGCGGGTGAC
GAGCTGTGGCGGTGAGTTCAAGATGCTGGAAACCAGCTTTTTCCTGTCGCGCCAGACCCTGATTGCGGCGAAGAAACCGG
GGATGCCGATCTGGCGCGAAAAGCTTTTCGCGTGGATGCTGCGCAATTCGGAAAGCGCGATGGAATATTTCCGTCTGCCA
AGTAATCGGGTGGTCGAACTGGGTAGCCAGGTCGCGATCTGA

Upstream 100 bases:

>100_bases
GCCGACGCCAGCGGCACCTGCGGGCCCGGCCGACGAAACCGTAGCGAGCGTCCCGAATTGAAACCTGTTCCAAAATCGCA
GGCTCGTCTAAAGGCGCGCG

Downstream 100 bases:

>100_bases
CCGGCGCGATCGATTTTCGGGCAGCAGGCGGTCGCAGTGGTGGAGAGCAGCCAACAAACGCGCCTGATATCCTCATCATG
ATGTCGCCGCAGTGATGGTC

Product: K+ potassium transporter

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 653; Mature: 652

Protein sequence:

>653_residues
MTAESQRAAEGVATAIEAAAETGHHGHGPHGDGKLKLAVGAVGVVFGDIGTSPLYAFRETFAGHHPIEPDRLHIYGVLSL
VFWSMMLVVTFKYVMTIMRADNKGEGGSLALLALISRSSEGKRWTWPIVLLGVFATALFYGDSMITPAMSVLSATEGLSY
VDKGFEPYIVPIALGILIGLFAIQARGTAKVGALFGPIMLLYFLMLAGLGILHIGNNPWIIVETLNPVNALRFFYLDGFT
AFIALGAVVLAVTGAEALYADMGHFGRGPIGLSWLSFVLPALMLNYMGQGAMVLAAEAGPRTELIADPFFQMMPQFLELP
VVILALLATIIASQAVISGAFSLTQQAIQLGFMPRLRVEHTSASAAGQIYIPIVNWGLMVMVILLVLGFGSSSNLAAAYG
IAVTGAMFIDTCLMSVVLFTLWKWPAWKALPVLAVFFIVDIAYFGANLIKVPDGGWVPLVIGLTIFTLLTTWSRGRKLMQ
EEMAEGAMPIPIFVKSAANSATRVPGTAVFMTSSSDGVPHALLHNLKHNKVLHERIILLTIKIADVPFVPESKLCQLEDL
GQGFHRLVLNYGFMQPIDVPEALMRVTSCGGEFKMLETSFFLSRQTLIAAKKPGMPIWREKLFAWMLRNSESAMEYFRLP
SNRVVELGSQVAI

Sequences:

>Translated_653_residues
MTAESQRAAEGVATAIEAAAETGHHGHGPHGDGKLKLAVGAVGVVFGDIGTSPLYAFRETFAGHHPIEPDRLHIYGVLSL
VFWSMMLVVTFKYVMTIMRADNKGEGGSLALLALISRSSEGKRWTWPIVLLGVFATALFYGDSMITPAMSVLSATEGLSY
VDKGFEPYIVPIALGILIGLFAIQARGTAKVGALFGPIMLLYFLMLAGLGILHIGNNPWIIVETLNPVNALRFFYLDGFT
AFIALGAVVLAVTGAEALYADMGHFGRGPIGLSWLSFVLPALMLNYMGQGAMVLAAEAGPRTELIADPFFQMMPQFLELP
VVILALLATIIASQAVISGAFSLTQQAIQLGFMPRLRVEHTSASAAGQIYIPIVNWGLMVMVILLVLGFGSSSNLAAAYG
IAVTGAMFIDTCLMSVVLFTLWKWPAWKALPVLAVFFIVDIAYFGANLIKVPDGGWVPLVIGLTIFTLLTTWSRGRKLMQ
EEMAEGAMPIPIFVKSAANSATRVPGTAVFMTSSSDGVPHALLHNLKHNKVLHERIILLTIKIADVPFVPESKLCQLEDL
GQGFHRLVLNYGFMQPIDVPEALMRVTSCGGEFKMLETSFFLSRQTLIAAKKPGMPIWREKLFAWMLRNSESAMEYFRLP
SNRVVELGSQVAI
>Mature_652_residues
TAESQRAAEGVATAIEAAAETGHHGHGPHGDGKLKLAVGAVGVVFGDIGTSPLYAFRETFAGHHPIEPDRLHIYGVLSLV
FWSMMLVVTFKYVMTIMRADNKGEGGSLALLALISRSSEGKRWTWPIVLLGVFATALFYGDSMITPAMSVLSATEGLSYV
DKGFEPYIVPIALGILIGLFAIQARGTAKVGALFGPIMLLYFLMLAGLGILHIGNNPWIIVETLNPVNALRFFYLDGFTA
FIALGAVVLAVTGAEALYADMGHFGRGPIGLSWLSFVLPALMLNYMGQGAMVLAAEAGPRTELIADPFFQMMPQFLELPV
VILALLATIIASQAVISGAFSLTQQAIQLGFMPRLRVEHTSASAAGQIYIPIVNWGLMVMVILLVLGFGSSSNLAAAYGI
AVTGAMFIDTCLMSVVLFTLWKWPAWKALPVLAVFFIVDIAYFGANLIKVPDGGWVPLVIGLTIFTLLTTWSRGRKLMQE
EMAEGAMPIPIFVKSAANSATRVPGTAVFMTSSSDGVPHALLHNLKHNKVLHERIILLTIKIADVPFVPESKLCQLEDLG
QGFHRLVLNYGFMQPIDVPEALMRVTSCGGEFKMLETSFFLSRQTLIAAKKPGMPIWREKLFAWMLRNSESAMEYFRLPS
NRVVELGSQVAI

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=626, Percent_Identity=47.1246006389776, Blast_Score=547, Evalue=1e-157,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP_SPHAL (Q1GSZ7)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_616558.1
- GeneID:   4080025
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_1512
- NMPDR:   fig|317655.9.peg.1445
- HOGENOM:   HBG351154
- OMA:   ETINIPR
- ProtClustDB:   CLSK835383
- BioCyc:   SALA317655:SALA_1512-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 70743; Mature: 70611

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1289bb9c)-; HASH(0x1115265c)-; HASH(0x12bb4e3c)-; HASH(0x12232ef0)-; HASH(0x12ae680c)-; HASH(0x111524c4)-; HASH(0x114a65a4)-; HASH(0x12aee2b0)-; HASH(0x12ad4c54)-; HASH(0x11c4b268)-; HASH(0x12bb4e6c)-; HASH(0x12af097c)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAESQRAAEGVATAIEAAAETGHHGHGPHGDGKLKLAVGAVGVVFGDIGTSPLYAFRET
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEHHHHHHHCCCCCHHHHHHHH
FAGHHPIEPDRLHIYGVLSLVFWSMMLVVTFKYVMTIMRADNKGEGGSLALLALISRSSE
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCC
GKRWTWPIVLLGVFATALFYGDSMITPAMSVLSATEGLSYVDKGFEPYIVPIALGILIGL
CCEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHH
FAIQARGTAKVGALFGPIMLLYFLMLAGLGILHIGNNPWIIVETLNPVNALRFFYLDGFT
HHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHH
AFIALGAVVLAVTGAEALYADMGHFGRGPIGLSWLSFVLPALMLNYMGQGAMVLAAEAGP
HHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
RTELIADPFFQMMPQFLELPVVILALLATIIASQAVISGAFSLTQQAIQLGFMPRLRVEH
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
TSASAAGQIYIPIVNWGLMVMVILLVLGFGSSSNLAAAYGIAVTGAMFIDTCLMSVVLFT
CCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LWKWPAWKALPVLAVFFIVDIAYFGANLIKVPDGGWVPLVIGLTIFTLLTTWSRGRKLMQ
HHCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EEMAEGAMPIPIFVKSAANSATRVPGTAVFMTSSSDGVPHALLHNLKHNKVLHERIILLT
HHHHCCCCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHEEEEEE
IKIADVPFVPESKLCQLEDLGQGFHRLVLNYGFMQPIDVPEALMRVTSCGGEFKMLETSF
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEHHHH
FLSRQTLIAAKKPGMPIWREKLFAWMLRNSESAMEYFRLPSNRVVELGSQVAI
HHHHHHHHEECCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHCCCCCCH
>Mature Secondary Structure 
TAESQRAAEGVATAIEAAAETGHHGHGPHGDGKLKLAVGAVGVVFGDIGTSPLYAFRET
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEHHHHHHHCCCCCHHHHHHHH
FAGHHPIEPDRLHIYGVLSLVFWSMMLVVTFKYVMTIMRADNKGEGGSLALLALISRSSE
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCC
GKRWTWPIVLLGVFATALFYGDSMITPAMSVLSATEGLSYVDKGFEPYIVPIALGILIGL
CCEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHH
FAIQARGTAKVGALFGPIMLLYFLMLAGLGILHIGNNPWIIVETLNPVNALRFFYLDGFT
HHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHH
AFIALGAVVLAVTGAEALYADMGHFGRGPIGLSWLSFVLPALMLNYMGQGAMVLAAEAGP
HHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
RTELIADPFFQMMPQFLELPVVILALLATIIASQAVISGAFSLTQQAIQLGFMPRLRVEH
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
TSASAAGQIYIPIVNWGLMVMVILLVLGFGSSSNLAAAYGIAVTGAMFIDTCLMSVVLFT
CCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LWKWPAWKALPVLAVFFIVDIAYFGANLIKVPDGGWVPLVIGLTIFTLLTTWSRGRKLMQ
HHCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EEMAEGAMPIPIFVKSAANSATRVPGTAVFMTSSSDGVPHALLHNLKHNKVLHERIILLT
HHHHCCCCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHEEEEEE
IKIADVPFVPESKLCQLEDLGQGFHRLVLNYGFMQPIDVPEALMRVTSCGGEFKMLETSF
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEHHHH
FLSRQTLIAAKKPGMPIWREKLFAWMLRNSESAMEYFRLPSNRVVELGSQVAI
HHHHHHHHEECCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA