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The map label for this gene is aroA

Identifier: 103486978

GI number: 103486978

Start: 1555610

End: 1556950

Strand: Direct

Name: aroA

Synonym: Sala_1493

Alternate gene names: 103486978

Gene position: 1555610-1556950 (Clockwise)

Preceding gene: 103486976

Following gene: 103486979

Centisome position: 46.5

GC content: 67.93

Gene sequence:

>1341_bases
ATGACCGACCAAACCGCCACACCGCGCAGCTTTTCTGCCTCCGTTCCGTTGAAGGGCAGGATCGCCATTCCGGGCGACAA
GAGCATCTCGCACCGATCGCTGATGCTGTCGGCGCTGGCCGTCGGCGAAAGCCGCGTCGCCGGCCTGCTCGAAGGGCATG
ATGTCCTCGCGACCGCCGCCGCGATGCGCGCCATGGGGGCCGATATCGCGCGCCGCGACGACGGCGAATGGCGCATCCAC
GGCGTCGGCGTCGGCGGCTTGCTCCAGCCGCGGGGCGCGCTCGACATGGGGAACAGCGGCACGTCGACACGTCTGCTGAT
GGGGCTCGTCGCGAGCCACCCGATCACCGCCACTTTCGTCGGCGACGCCAGCCTGTCGGGTCGCCCGATGGGGCGCGTCA
TCGATCCGCTGACCCAGATGGGCGCCGACATCAGCGCCTCGCCGGGCGCCAGGGGGGCAAAAACTCTGCCGCTGATGGTC
CGCGGCCTCGCGCCCGCCATTCCCCTCTCCTACCGCCTGCCGATGGCGTCGGCGCAGGTGAAGAGCGCGATCCTTCTCGC
CGGACTCAATACGCCCGGCGTCACCGAAGTCATCGAGCCGGTGCCCACGCGCGACCACAGCGAGCGGATGCTCGGCGCCT
TTGGCGCCGATCTGACCGTCGACATCGACGCGGGCGGCACGCGCCATATCCGTATCCGCGGCGAAGCCGATCTCAAGCCG
CAGGCGATCATCGTCCCCGGTGATCCCTCCTCGGCCGCCTTCTTTATCGTTGCGGCGCTCATCGTGCCCGGTTCGGACGT
CACCATCGCCAACGTCGGTCTCAATCCGACGCGCGCCGGGCTGGTCGAGGTTCTGAAGGCGATGGGCGGCGACATCGAAC
TGCTCGACCGGCGCGAAATCGGCGGCGAACCCGTCGCCGACCTGCGCGTGCGCCACAGCGTGCTCAAAGGCATCGAGGTC
GACCCGGCGGTTGCGCCGAGCATGATCGATGAGTTTCCAGTCCTCTTCGTTGCCGCGACGCTCGCCGAAGGCCGCACGGT
GACCACGGGGCTCGATGAACTGCGCGTCAAGGAAAGCGACCGCCTTGCCGTCATGGCGACCGGGCTCAAGGCCATCGGCG
CGCGTGTCGAGGAAAGCCAAGACGGCCTTGTCATTGATGGCACCGGCGGCGATCCGCTAGCCGGCGGCGCGACCATCGCC
GGCCATCTCGATCATCGCATCTGCATGAGCTTCGCAATCGCGGGGCTTGTCAGCAAGGCGCCGGTGACGGTCGACGACAT
CGCCCCCGTCGCAACGAGCTTCCCCAATTTCGAGGCATTGCTTGCGGGTTTGCAACAATGA

Upstream 100 bases:

>100_bases
AGGATAAAAATATCGGAAGAACGACGACGCCTGAATAGCTATCCGTCAAATCGGCGTGCGCCTTGCCAGATTGCAAGGCC
GCTGTCAAAAGCCGCACGCG

Downstream 100 bases:

>100_bases
TCATCGCCATCGATGGCCCCACCGCATCGGGCAAGGGCACGCTTGCTCGCCAGCTCGCAGACCATTTCGGCCTGCCGGTA
CTCGACACCGGCCTCCTGTA

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MTDQTATPRSFSASVPLKGRIAIPGDKSISHRSLMLSALAVGESRVAGLLEGHDVLATAAAMRAMGADIARRDDGEWRIH
GVGVGGLLQPRGALDMGNSGTSTRLLMGLVASHPITATFVGDASLSGRPMGRVIDPLTQMGADISASPGARGAKTLPLMV
RGLAPAIPLSYRLPMASAQVKSAILLAGLNTPGVTEVIEPVPTRDHSERMLGAFGADLTVDIDAGGTRHIRIRGEADLKP
QAIIVPGDPSSAAFFIVAALIVPGSDVTIANVGLNPTRAGLVEVLKAMGGDIELLDRREIGGEPVADLRVRHSVLKGIEV
DPAVAPSMIDEFPVLFVAATLAEGRTVTTGLDELRVKESDRLAVMATGLKAIGARVEESQDGLVIDGTGGDPLAGGATIA
GHLDHRICMSFAIAGLVSKAPVTVDDIAPVATSFPNFEALLAGLQQ

Sequences:

>Translated_446_residues
MTDQTATPRSFSASVPLKGRIAIPGDKSISHRSLMLSALAVGESRVAGLLEGHDVLATAAAMRAMGADIARRDDGEWRIH
GVGVGGLLQPRGALDMGNSGTSTRLLMGLVASHPITATFVGDASLSGRPMGRVIDPLTQMGADISASPGARGAKTLPLMV
RGLAPAIPLSYRLPMASAQVKSAILLAGLNTPGVTEVIEPVPTRDHSERMLGAFGADLTVDIDAGGTRHIRIRGEADLKP
QAIIVPGDPSSAAFFIVAALIVPGSDVTIANVGLNPTRAGLVEVLKAMGGDIELLDRREIGGEPVADLRVRHSVLKGIEV
DPAVAPSMIDEFPVLFVAATLAEGRTVTTGLDELRVKESDRLAVMATGLKAIGARVEESQDGLVIDGTGGDPLAGGATIA
GHLDHRICMSFAIAGLVSKAPVTVDDIAPVATSFPNFEALLAGLQQ
>Mature_445_residues
TDQTATPRSFSASVPLKGRIAIPGDKSISHRSLMLSALAVGESRVAGLLEGHDVLATAAAMRAMGADIARRDDGEWRIHG
VGVGGLLQPRGALDMGNSGTSTRLLMGLVASHPITATFVGDASLSGRPMGRVIDPLTQMGADISASPGARGAKTLPLMVR
GLAPAIPLSYRLPMASAQVKSAILLAGLNTPGVTEVIEPVPTRDHSERMLGAFGADLTVDIDAGGTRHIRIRGEADLKPQ
AIIVPGDPSSAAFFIVAALIVPGSDVTIANVGLNPTRAGLVEVLKAMGGDIELLDRREIGGEPVADLRVRHSVLKGIEVD
PAVAPSMIDEFPVLFVAATLAEGRTVTTGLDELRVKESDRLAVMATGLKAIGARVEESQDGLVIDGTGGDPLAGGATIAG
HLDHRICMSFAIAGLVSKAPVTVDDIAPVATSFPNFEALLAGLQQ

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=440, Percent_Identity=30.2272727272727, Blast_Score=126, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6320332, Length=430, Percent_Identity=27.2093023255814, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_SPHAL (Q1GT16)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_616539.1
- ProteinModelPortal:   Q1GT16
- SMR:   Q1GT16
- GeneID:   4081170
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_1493
- NMPDR:   fig|317655.9.peg.1426
- HOGENOM:   HBG646626
- OMA:   LSRNHTE
- ProtClustDB:   PRK02427
- BioCyc:   SALA317655:SALA_1493-MONOMER
- BRENDA:   2.5.1.19
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 45958; Mature: 45826

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQTATPRSFSASVPLKGRIAIPGDKSISHRSLMLSALAVGESRVAGLLEGHDVLATAA
CCCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCHHHHHHHHCCCHHHHHHH
AMRAMGADIARRDDGEWRIHGVGVGGLLQPRGALDMGNSGTSTRLLMGLVASHPITATFV
HHHHHCCHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEE
GDASLSGRPMGRVIDPLTQMGADISASPGARGAKTLPLMVRGLAPAIPLSYRLPMASAQV
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEECCCCHHHH
KSAILLAGLNTPGVTEVIEPVPTRDHSERMLGAFGADLTVDIDAGGTRHIRIRGEADLKP
HCEEEEEECCCCCHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCCEEEEEEECCCCCCC
QAIIVPGDPSSAAFFIVAALIVPGSDVTIANVGLNPTRAGLVEVLKAMGGDIELLDRREI
CEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEHHHC
GGEPVADLRVRHSVLKGIEVDPAVAPSMIDEFPVLFVAATLAEGRTVTTGLDELRVKESD
CCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCHHHHHCCCCC
RLAVMATGLKAIGARVEESQDGLVIDGTGGDPLAGGATIAGHLDHRICMSFAIAGLVSKA
CEEEEECCHHHHCCCCCCCCCCEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCC
PVTVDDIAPVATSFPNFEALLAGLQQ
CCCHHHCCHHHHCCCCHHHHHHHHCC
>Mature Secondary Structure 
TDQTATPRSFSASVPLKGRIAIPGDKSISHRSLMLSALAVGESRVAGLLEGHDVLATAA
CCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCHHHHHHHHCCCHHHHHHH
AMRAMGADIARRDDGEWRIHGVGVGGLLQPRGALDMGNSGTSTRLLMGLVASHPITATFV
HHHHHCCHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEE
GDASLSGRPMGRVIDPLTQMGADISASPGARGAKTLPLMVRGLAPAIPLSYRLPMASAQV
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEECCCCHHHH
KSAILLAGLNTPGVTEVIEPVPTRDHSERMLGAFGADLTVDIDAGGTRHIRIRGEADLKP
HCEEEEEECCCCCHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCCEEEEEEECCCCCCC
QAIIVPGDPSSAAFFIVAALIVPGSDVTIANVGLNPTRAGLVEVLKAMGGDIELLDRREI
CEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEHHHC
GGEPVADLRVRHSVLKGIEVDPAVAPSMIDEFPVLFVAATLAEGRTVTTGLDELRVKESD
CCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCHHHHHCCCCC
RLAVMATGLKAIGARVEESQDGLVIDGTGGDPLAGGATIAGHLDHRICMSFAIAGLVSKA
CEEEEECCHHHHCCCCCCCCCCEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCC
PVTVDDIAPVATSFPNFEALLAGLQQ
CCCHHHCCHHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA