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The map label for this gene is rpoC

Identifier: 103486970

GI number: 103486970

Start: 1542641

End: 1546924

Strand: Reverse

Name: rpoC

Synonym: Sala_1485

Alternate gene names: 103486970

Gene position: 1546924-1542641 (Counterclockwise)

Preceding gene: 103486971

Following gene: 103486969

Centisome position: 46.24

GC content: 62.25

Gene sequence:

>4284_bases
ATGAACCAGCTTACCAACTTCATGAACCCGGTCGCGAAGCCCGAAACCTTCGACATGATCAAGATCGGCATCGCGAGCCC
CGAGCGCATCCGCTCGTGGTCGTTTGGCGAGATCAAGAAGCCCGAAACGATCAACTACCGCACGTTCAAGCCTGAACGTG
ACGGGCTGTTCTGCGCGCGCATTTTCGGTCCGATCAAGGATTATGAATGCCTGTGCGGCAAGTACAAGCGTATGAAATAC
AAGGGCATCGTCTGCGAAAAATGCGGTGTCGAAGTCACGGTCACGAAAGTGCGCCGCGAGCGCATGGGCCATATCGAGCT
TGCCGCACCCGTCGCGCACATCTGGTTCCTGAAGTCGCTGCCGTCGCGCATCGGCCTGCTGCTCGACATGCAGCTCAAGC
AGCTCGAGCGCGTCCTCTATTTCGAAGCCTATATCGTCCTTGAGCCCGGCCTGACCCCGCTCGAGAAGTTCCAGCTGCTG
ACCGAAGACGAACTGCTCGACGCGCAGGACGAGTATGGCGAAGATGCTTTTTCGGCCGGTATCGGCGCCGAGGCGATCCG
CACTCTGCTCGAAAATCTCGACCTCGAGCAGGAACGCACCGACCTGATGGAAGAGCTGGCGACGACCAAGTCGGAGCTCA
AGCCCAAGAAGATCATCAAGCGCCTGAAAGTCGTGGAATCCTTCATCGAATCGGGCAACCGCCCCGAATGGATGATCCTG
GAGGTCGTTCCGGTCATCCCGCCCGAACTGCGCCCGCTGGTGCCGCTCGACGGCGGCCGCTTCGCGACGTCGGACCTCAA
CGACCTCTATCGCCGCGTCATCAACCGCAACAACCGTCTGAAGCGCCTGATGGAACTGCGTGCGCCGGACATCATCGTCC
GCAACGAGAAGCGCATGTTGCAGGAAGCCGTCGACGCGCTGTTCGACAACGGCCGCCGCGGTCGCACGATCACCGGCGCC
AACAAGCGTCCGCTGAAGTCGCTGTCCGACATGCTCAAGGGCAAGCAGGGCCGCTTCCGCCAGAACCTGCTCGGCAAGCG
CGTCGACTATTCGGGCCGTTCGGTGATCGTCACCGGTCCCGAACTCAAGCTGCACCAGTGCGGCCTGCCCAAGAAGATGG
CGCTCGAGCTTTTCAAGCCGTTCATCTATGCGCGCCTCGACGCCAAGGGTCTGTCGATGACCCTCAAGCAGGCGAAGAAG
TGGGTCGAGAAGGAGCGCAAGGAAGTCTGGGACATCCTCGACGAGGTTATTCGCGAGCACCCGGTCCTCCTGAACCGTGC
CCCGACGCTCCACCGCCTCGGCATCCAGGCGTTCGAGCCGGTGCTGATCGAGGGCAAGGCGATCCAGCTGCACCCGCTGG
TCTGCGCCGCGTTCAACGCCGACTTCGACGGCGACCAGATGGCGGTCCACGTCCCGCTCTCGCTGGAAGCCCAGCTGGAA
GCGCGCGTGCTGATGATGTCGACCAACAACATCCTCAGCCCCGCAAACGGCAAGCCGATCATCGTGCCGTCGCAGGACAT
GGTTCTCGGCCTCTATTATCTCTCGCTGGAGCGCGAAGGCGAGCCGGGCGAAGGCATGTTGCTCGCCGATATGGCCGAAG
TCCATCAGGCGCTGCATATCGGCGCGGTCACGCTGCACTCGAAAATCATCAGCCGCGTTCCGCAGACCGACGAGAAGGGC
AATGAATATCTGAAGCGCTTTGAAACCACGCCGGGCCGTATGCTGATCGGCGAATGCCTGCCGAAGTCGCACACTGTGCC
CTTTGACGTCGTCAACCGCCTTCTGACCAAGAAGGAAATCGGCGACGTGATCGACCAGGTCTATCGCCATACCGGCCAGA
AGGAGACGGTGCTGTTCGCCGACGCCATCATGGCGCTGGGTTTCCGTCATGCTTTCAAGGCGGGCATCTCGTTCGGCAAG
GACGACATGATCATTCCGGCTTCGAAGGAGCAGCTGGTCGACGAAACCCGCTCGCTGGTGAAGGATTTCGAGCAGCAGTA
TCAGGACGGCCTGATCACGCAGCAGGAAAAATATAACAAGGCGATCGATGCCTGGTCGCAGTGCGGCGACAAGGTCGCGA
ACGCGATGATGGACGAAATCCGCGCTACGCCGAAGCTGCCCGACGGCCGTCTGGCCCCGATCAACTCCATCTATATGATG
GCGCATTCGGGTGCCCGCGGCTCGCAGGCACAGATGAAGCAGCTCGCCGGCATGCGCGGCCTGATGGCCAAGCCGTCGGG
CGAGATCATCGAAACGCCGATCATCTCGAACTTCAAGGAAGGCCTGACCGTTCTCGAGTATTTCAACTCGACCCACGGTG
CGCGCAAGGGTCTGGCCGATACGGCGCTCAAGACGGCAAACTCGGGTTATCTGACCCGCCGTCTGGTCGACGTGTCGCAG
GATTGCGTCGTGATCGAGGAAGATTGCGGCACCACCCGCGGCATGGAAATGCGCGCGATCATCCAGGGCGGCTCGACGAT
CGCCTCGCTCGGCGAGCGCATCCTCGGTCGCACGACGCTGGAAGACGTCGTCGACAAGGACGGCAATGTCATCGCGCCCG
TCGGCACCTTGCTTGACGAAGCGACAACGCAGCGGATCGAAGAGGCCGAGGTCCAGTCGGTCAAGATTCGCTCGCCGCTC
GTTTGCGAAGCGACGCTGGGCGTTTGCGGCAAATGCTATGGCCGCGACCTGGCCCGCGGCACGCCGGTCAATATCGGCGA
AGCGGTGGGGGTTATCGCTGCGCAGTCGATCGGCGAACCCGGCACCCAGCTGACCATGCGCACCTTCCACATTGGCGGGG
CGGCGCAGGTCAACGAACAGTCGAACGTCGAGGCGATTTCGGACGGTACGATCGAATATCGCGACATGGCGACGATCGTC
GACCAGCGCGGCCGCCGCCTGGCGCTGTCGCGTTCGGGCGAGATCGCGATCATCGACAGCGAAGGCCGCGAACGCGCGTC
GCACAAGCTGCCCTATGGTGCGCAGATCATGCACAAGGACGGCGAAAAGGTGAAGAAGGGCGACCGGATTGCCGAATGGG
ATCCGTTCACCATGCCGCTGATCACCGAAAAGCAGGGCGTTGTGAAATATCAGGATCTGATCGACGGCAAGACGCTGACC
GAACAGGTCGACGAAGCGACGGGCATCGCCCAGCGCGTGGTGATCGAATATCGCGCCGCCGGACGCAGCAAGAAGGAAGA
CCTTCAGCCGCGCATCACCCTGCTCGACGACGCATCGGGCGAAGCTGCACGCTATCTGCTCGCGGTCGGCACGATGATCT
CAGTCGAGGACGGGCAGACGGTGCAGGCGGGCGACGTACTGGCGCGTGTGAGCCGCGAAGCGTCGAAGACGCGCGACATC
ACCGGCGGTCTGCCGCGGGTTGCCGAGCTGTTCGAAGCGCGCATTCCGAAGGATAACAGCGTCATCGCGAAGATCAGCGG
CCGCATTGAGTTCGTCAAGGACTACAAGGCGAAGCGCAAGATCGCGATCGTTCCGGAAGAAGGCGATCCGATCGAATATC
TGATCCCCAAGTCGAAGGTGCTGGAAGTGCAGGAAGGCGACATGGTCAAGCGCGGCGATGCGCTGATCTCCGGCTCGCCG
AACCCGCATGACATCCTCGACGTCATGGGCGTCGAGGCGCTGGCCGAATATCTGGTCGCGGAGATCCAGGAAGTCTATCG
ACTCCAGGGCGTGAAGATCAACGACAAGCACATCGAGGTGATCGTTCGCCAGATGCTGCAGAAGGTCGAGATCACCGATG
GCGGCGACACCACGCTGCTGCCGGGCGAACAGCTCGATTATCTGGAGATGATGGAATATAACGCCAAACTGCCCAAGAAC
GGCAAACCGGCCGAGGGCCGCCCGGTCCTCCTCGGCATCACCAAGGCGAGCCTGCAAACGCGCAGCTTCGTTTCGGCGGC
GTCCTTCCAGGAAACGACCCGCGTTCTCACCGAAGCGTCGGTGCAGGGCAAGGTCGACTCGCTGCAGGGGCTCAAGGAAA
ATGTCATCGTCGGCCGCCTCATCCCGGCGGGTACCGGCGCTGCCATGAACCGTGTCCGCGTCACCGCCTCGTCGAAGGAT
GCCGCGCTGCGCGCCGCGATGCGTGTTGCGAACCAGGAGCATCTCATTGCGCCGCGGACCGCAGCCGAGGAGCATGCGGC
CGAACTCGCGCAGGGCCCCGAAGCGGCGATCGGCGACGATCCGCTGGGCAAGGTGCAGGGTGAGGATTTCACGACCGACG
ATGTGATGGTCGAGGAACGCCCCGAAGGCGCCAGCGAGGAATAA

Upstream 100 bases:

>100_bases
AGATCCCGACGAAGGTCCCGAAGCCCTTCCCGAAGCCGCCGAATAAGATTTTTCCTCACCCCTCTCGCCCCGGCGCGAGA
GGGGAAGATGGAGCAGACAA

Downstream 100 bases:

>100_bases
GCCGCTTGCGCTCTTGGCCATGAAAAAAGCCCCGCCGGAACGATCCGGCGGGGCTTTTTTTGGCCGCCGATAATGGCGGG
ATCGCCACCCGGCAGGGGGA

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1427; Mature: 1427

Protein sequence:

>1427_residues
MNQLTNFMNPVAKPETFDMIKIGIASPERIRSWSFGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKY
KGIVCEKCGVEVTVTKVRRERMGHIELAAPVAHIWFLKSLPSRIGLLLDMQLKQLERVLYFEAYIVLEPGLTPLEKFQLL
TEDELLDAQDEYGEDAFSAGIGAEAIRTLLENLDLEQERTDLMEELATTKSELKPKKIIKRLKVVESFIESGNRPEWMIL
EVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELRAPDIIVRNEKRMLQEAVDALFDNGRRGRTITGA
NKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYARLDAKGLSMTLKQAKK
WVEKERKEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQLE
ARVLMMSTNNILSPANGKPIIVPSQDMVLGLYYLSLEREGEPGEGMLLADMAEVHQALHIGAVTLHSKIISRVPQTDEKG
NEYLKRFETTPGRMLIGECLPKSHTVPFDVVNRLLTKKEIGDVIDQVYRHTGQKETVLFADAIMALGFRHAFKAGISFGK
DDMIIPASKEQLVDETRSLVKDFEQQYQDGLITQQEKYNKAIDAWSQCGDKVANAMMDEIRATPKLPDGRLAPINSIYMM
AHSGARGSQAQMKQLAGMRGLMAKPSGEIIETPIISNFKEGLTVLEYFNSTHGARKGLADTALKTANSGYLTRRLVDVSQ
DCVVIEEDCGTTRGMEMRAIIQGGSTIASLGERILGRTTLEDVVDKDGNVIAPVGTLLDEATTQRIEEAEVQSVKIRSPL
VCEATLGVCGKCYGRDLARGTPVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQVNEQSNVEAISDGTIEYRDMATIV
DQRGRRLALSRSGEIAIIDSEGRERASHKLPYGAQIMHKDGEKVKKGDRIAEWDPFTMPLITEKQGVVKYQDLIDGKTLT
EQVDEATGIAQRVVIEYRAAGRSKKEDLQPRITLLDDASGEAARYLLAVGTMISVEDGQTVQAGDVLARVSREASKTRDI
TGGLPRVAELFEARIPKDNSVIAKISGRIEFVKDYKAKRKIAIVPEEGDPIEYLIPKSKVLEVQEGDMVKRGDALISGSP
NPHDILDVMGVEALAEYLVAEIQEVYRLQGVKINDKHIEVIVRQMLQKVEITDGGDTTLLPGEQLDYLEMMEYNAKLPKN
GKPAEGRPVLLGITKASLQTRSFVSAASFQETTRVLTEASVQGKVDSLQGLKENVIVGRLIPAGTGAAMNRVRVTASSKD
AALRAAMRVANQEHLIAPRTAAEEHAAELAQGPEAAIGDDPLGKVQGEDFTTDDVMVEERPEGASEE

Sequences:

>Translated_1427_residues
MNQLTNFMNPVAKPETFDMIKIGIASPERIRSWSFGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKY
KGIVCEKCGVEVTVTKVRRERMGHIELAAPVAHIWFLKSLPSRIGLLLDMQLKQLERVLYFEAYIVLEPGLTPLEKFQLL
TEDELLDAQDEYGEDAFSAGIGAEAIRTLLENLDLEQERTDLMEELATTKSELKPKKIIKRLKVVESFIESGNRPEWMIL
EVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELRAPDIIVRNEKRMLQEAVDALFDNGRRGRTITGA
NKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYARLDAKGLSMTLKQAKK
WVEKERKEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQLE
ARVLMMSTNNILSPANGKPIIVPSQDMVLGLYYLSLEREGEPGEGMLLADMAEVHQALHIGAVTLHSKIISRVPQTDEKG
NEYLKRFETTPGRMLIGECLPKSHTVPFDVVNRLLTKKEIGDVIDQVYRHTGQKETVLFADAIMALGFRHAFKAGISFGK
DDMIIPASKEQLVDETRSLVKDFEQQYQDGLITQQEKYNKAIDAWSQCGDKVANAMMDEIRATPKLPDGRLAPINSIYMM
AHSGARGSQAQMKQLAGMRGLMAKPSGEIIETPIISNFKEGLTVLEYFNSTHGARKGLADTALKTANSGYLTRRLVDVSQ
DCVVIEEDCGTTRGMEMRAIIQGGSTIASLGERILGRTTLEDVVDKDGNVIAPVGTLLDEATTQRIEEAEVQSVKIRSPL
VCEATLGVCGKCYGRDLARGTPVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQVNEQSNVEAISDGTIEYRDMATIV
DQRGRRLALSRSGEIAIIDSEGRERASHKLPYGAQIMHKDGEKVKKGDRIAEWDPFTMPLITEKQGVVKYQDLIDGKTLT
EQVDEATGIAQRVVIEYRAAGRSKKEDLQPRITLLDDASGEAARYLLAVGTMISVEDGQTVQAGDVLARVSREASKTRDI
TGGLPRVAELFEARIPKDNSVIAKISGRIEFVKDYKAKRKIAIVPEEGDPIEYLIPKSKVLEVQEGDMVKRGDALISGSP
NPHDILDVMGVEALAEYLVAEIQEVYRLQGVKINDKHIEVIVRQMLQKVEITDGGDTTLLPGEQLDYLEMMEYNAKLPKN
GKPAEGRPVLLGITKASLQTRSFVSAASFQETTRVLTEASVQGKVDSLQGLKENVIVGRLIPAGTGAAMNRVRVTASSKD
AALRAAMRVANQEHLIAPRTAAEEHAAELAQGPEAAIGDDPLGKVQGEDFTTDDVMVEERPEGASEE
>Mature_1427_residues
MNQLTNFMNPVAKPETFDMIKIGIASPERIRSWSFGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKY
KGIVCEKCGVEVTVTKVRRERMGHIELAAPVAHIWFLKSLPSRIGLLLDMQLKQLERVLYFEAYIVLEPGLTPLEKFQLL
TEDELLDAQDEYGEDAFSAGIGAEAIRTLLENLDLEQERTDLMEELATTKSELKPKKIIKRLKVVESFIESGNRPEWMIL
EVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELRAPDIIVRNEKRMLQEAVDALFDNGRRGRTITGA
NKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYARLDAKGLSMTLKQAKK
WVEKERKEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQLE
ARVLMMSTNNILSPANGKPIIVPSQDMVLGLYYLSLEREGEPGEGMLLADMAEVHQALHIGAVTLHSKIISRVPQTDEKG
NEYLKRFETTPGRMLIGECLPKSHTVPFDVVNRLLTKKEIGDVIDQVYRHTGQKETVLFADAIMALGFRHAFKAGISFGK
DDMIIPASKEQLVDETRSLVKDFEQQYQDGLITQQEKYNKAIDAWSQCGDKVANAMMDEIRATPKLPDGRLAPINSIYMM
AHSGARGSQAQMKQLAGMRGLMAKPSGEIIETPIISNFKEGLTVLEYFNSTHGARKGLADTALKTANSGYLTRRLVDVSQ
DCVVIEEDCGTTRGMEMRAIIQGGSTIASLGERILGRTTLEDVVDKDGNVIAPVGTLLDEATTQRIEEAEVQSVKIRSPL
VCEATLGVCGKCYGRDLARGTPVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQVNEQSNVEAISDGTIEYRDMATIV
DQRGRRLALSRSGEIAIIDSEGRERASHKLPYGAQIMHKDGEKVKKGDRIAEWDPFTMPLITEKQGVVKYQDLIDGKTLT
EQVDEATGIAQRVVIEYRAAGRSKKEDLQPRITLLDDASGEAARYLLAVGTMISVEDGQTVQAGDVLARVSREASKTRDI
TGGLPRVAELFEARIPKDNSVIAKISGRIEFVKDYKAKRKIAIVPEEGDPIEYLIPKSKVLEVQEGDMVKRGDALISGSP
NPHDILDVMGVEALAEYLVAEIQEVYRLQGVKINDKHIEVIVRQMLQKVEITDGGDTTLLPGEQLDYLEMMEYNAKLPKN
GKPAEGRPVLLGITKASLQTRSFVSAASFQETTRVLTEASVQGKVDSLQGLKENVIVGRLIPAGTGAAMNRVRVTASSKD
AALRAAMRVANQEHLIAPRTAAEEHAAELAQGPEAAIGDDPLGKVQGEDFTTDDVMVEERPEGASEE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI4505939, Length=921, Percent_Identity=24.3213897937025, Blast_Score=187, Evalue=7e-47,
Organism=Homo sapiens, GI39725938, Length=495, Percent_Identity=25.6565656565657, Blast_Score=129, Evalue=3e-29,
Organism=Homo sapiens, GI103471997, Length=250, Percent_Identity=30.8, Blast_Score=91, Evalue=6e-18,
Organism=Escherichia coli, GI2367335, Length=1420, Percent_Identity=59.6478873239437, Blast_Score=1678, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=301, Percent_Identity=31.8936877076412, Blast_Score=144, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI25145495, Length=489, Percent_Identity=26.5848670756646, Blast_Score=137, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6320061, Length=887, Percent_Identity=26.3810597519729, Blast_Score=187, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6324690, Length=727, Percent_Identity=25.0343878954608, Blast_Score=158, Evalue=5e-39,
Organism=Drosophila melanogaster, GI281360912, Length=868, Percent_Identity=26.6129032258064, Blast_Score=173, Evalue=1e-42,
Organism=Drosophila melanogaster, GI17530899, Length=555, Percent_Identity=25.5855855855856, Blast_Score=151, Evalue=3e-36,
Organism=Drosophila melanogaster, GI17647875, Length=357, Percent_Identity=24.9299719887955, Blast_Score=96, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_SPHAL (Q1GT24)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_616531.1
- ProteinModelPortal:   Q1GT24
- GeneID:   4081257
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_1485
- NMPDR:   fig|317655.9.peg.1418
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- ProtClustDB:   PRK00566
- BioCyc:   SALA317655:SALA_1485-MONOMER
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 158097; Mature: 158097

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQLTNFMNPVAKPETFDMIKIGIASPERIRSWSFGEIKKPETINYRTFKPERDGLFCAR
CCHHHHHHCCCCCCCCCCEEEEECCCHHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPIKDYECLCGKYKRMKYKGIVCEKCGVEVTVTKVRRERMGHIELAAPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHCCCEEEHHCCCEEEHHHHHHHHCCCEEHHHHHHHHHHHHHH
PSRIGLLLDMQLKQLERVLYFEAYIVLEPGLTPLEKFQLLTEDELLDAQDEYGEDAFSAG
HHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHCHHHHCCCHHHCCCHHHHCC
IGAEAIRTLLENLDLEQERTDLMEELATTKSELKPKKIIKRLKVVESFIESGNRPEWMIL
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEE
EVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELRAPDIIVRNEKRML
EEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHHH
QEAVDALFDNGRRGRTITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGP
HHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECC
ELKLHQCGLPKKMALELFKPFIYARLDAKGLSMTLKQAKKWVEKERKEVWDILDEVIREH
CEEEHHCCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQLE
CEEECCCCCHHHHCHHHCCCEEECCCEEEECCEEEEEECCCCCCCCEEEEECCCCCCCCC
ARVLMMSTNNILSPANGKPIIVPSQDMVLGLYYLSLEREGEPGEGMLLADMAEVHQALHI
EEEEEEECCCCCCCCCCCEEEECCCCCEEEEEEEEEECCCCCCCCEEHHHHHHHHHHHHH
GAVTLHSKIISRVPQTDEKGNEYLKRFETTPGRMLIGECLPKSHTVPFDVVNRLLTKKEI
HHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHH
GDVIDQVYRHTGQKETVLFADAIMALGFRHAFKAGISFGKDDMIIPASKEQLVDETRSLV
HHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHH
KDFEQQYQDGLITQQEKYNKAIDAWSQCGDKVANAMMDEIRATPKLPDGRLAPINSIYMM
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEE
AHSGARGSQAQMKQLAGMRGLMAKPSGEIIETPIISNFKEGLTVLEYFNSTHGARKGLAD
EECCCCCCHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHCCCHHHCCHHH
TALKTANSGYLTRRLVDVSQDCVVIEEDCGTTRGMEMRAIIQGGSTIASLGERILGRTTL
HHHHHCCCCHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHCCHHH
EDVVDKDGNVIAPVGTLLDEATTQRIEEAEVQSVKIRSPLVCEATLGVCGKCYGRDLARG
HHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHEEECCCCEEEHHHHHHHHHHHCCHHCCC
TPVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQVNEQSNVEAISDGTIEYRDMATIV
CCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCEEECCCCEEHHHHHHHH
DQRGRRLALSRSGEIAIIDSEGRERASHKLPYGAQIMHKDGEKVKKGDRIAEWDPFTMPL
HCCCCEEEEECCCCEEEECCCCHHHHHCCCCCCCCEEECCCHHHHCCCCCCCCCCCCCCE
ITEKQGVVKYQDLIDGKTLTEQVDEATGIAQRVVIEYRAAGRSKKEDLQPRITLLDDASG
EECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCC
EAARYLLAVGTMISVEDGQTVQAGDVLARVSREASKTRDITGGLPRVAELFEARIPKDNS
HHHHHHHHHCCEEEECCCCEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCC
VIAKISGRIEFVKDYKAKRKIAIVPEEGDPIEYLIPKSKVLEVQEGDMVKRGDALISGSP
EEEEECCCHHHHHHHCCCCEEEEECCCCCCCEEECCCHHEEEECCCCCEECCCEEECCCC
NPHDILDVMGVEALAEYLVAEIQEVYRLQGVKINDKHIEVIVRQMLQKVEITDGGDTTLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHCCCCCCCCCEEC
PGEQLDYLEMMEYNAKLPKNGKPAEGRPVLLGITKASLQTRSFVSAASFQETTRVLTEAS
CCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
VQGKVDSLQGLKENVIVGRLIPAGTGAAMNRVRVTASSKDAALRAAMRVANQEHLIAPRT
HCCCHHHHHHHHHCCEEEEEECCCCCCHHCEEEEEECCCHHHHHHHHHHCCCCCEECCCC
AAEEHAAELAQGPEAAIGDDPLGKVQGEDFTTDDVMVEERPEGASEE
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCC
>Mature Secondary Structure
MNQLTNFMNPVAKPETFDMIKIGIASPERIRSWSFGEIKKPETINYRTFKPERDGLFCAR
CCHHHHHHCCCCCCCCCCEEEEECCCHHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPIKDYECLCGKYKRMKYKGIVCEKCGVEVTVTKVRRERMGHIELAAPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHCCCEEEHHCCCEEEHHHHHHHHCCCEEHHHHHHHHHHHHHH
PSRIGLLLDMQLKQLERVLYFEAYIVLEPGLTPLEKFQLLTEDELLDAQDEYGEDAFSAG
HHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHCHHHHCCCHHHCCCHHHHCC
IGAEAIRTLLENLDLEQERTDLMEELATTKSELKPKKIIKRLKVVESFIESGNRPEWMIL
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEE
EVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELRAPDIIVRNEKRML
EEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHHH
QEAVDALFDNGRRGRTITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGP
HHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECC
ELKLHQCGLPKKMALELFKPFIYARLDAKGLSMTLKQAKKWVEKERKEVWDILDEVIREH
CEEEHHCCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQLE
CEEECCCCCHHHHCHHHCCCEEECCCEEEECCEEEEEECCCCCCCCEEEEECCCCCCCCC
ARVLMMSTNNILSPANGKPIIVPSQDMVLGLYYLSLEREGEPGEGMLLADMAEVHQALHI
EEEEEEECCCCCCCCCCCEEEECCCCCEEEEEEEEEECCCCCCCCEEHHHHHHHHHHHHH
GAVTLHSKIISRVPQTDEKGNEYLKRFETTPGRMLIGECLPKSHTVPFDVVNRLLTKKEI
HHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHH
GDVIDQVYRHTGQKETVLFADAIMALGFRHAFKAGISFGKDDMIIPASKEQLVDETRSLV
HHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHH
KDFEQQYQDGLITQQEKYNKAIDAWSQCGDKVANAMMDEIRATPKLPDGRLAPINSIYMM
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEE
AHSGARGSQAQMKQLAGMRGLMAKPSGEIIETPIISNFKEGLTVLEYFNSTHGARKGLAD
EECCCCCCHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHCCCHHHCCHHH
TALKTANSGYLTRRLVDVSQDCVVIEEDCGTTRGMEMRAIIQGGSTIASLGERILGRTTL
HHHHHCCCCHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHCCHHH
EDVVDKDGNVIAPVGTLLDEATTQRIEEAEVQSVKIRSPLVCEATLGVCGKCYGRDLARG
HHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHEEECCCCEEEHHHHHHHHHHHCCHHCCC
TPVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQVNEQSNVEAISDGTIEYRDMATIV
CCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCEEECCCCEEHHHHHHHH
DQRGRRLALSRSGEIAIIDSEGRERASHKLPYGAQIMHKDGEKVKKGDRIAEWDPFTMPL
HCCCCEEEEECCCCEEEECCCCHHHHHCCCCCCCCEEECCCHHHHCCCCCCCCCCCCCCE
ITEKQGVVKYQDLIDGKTLTEQVDEATGIAQRVVIEYRAAGRSKKEDLQPRITLLDDASG
EECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCC
EAARYLLAVGTMISVEDGQTVQAGDVLARVSREASKTRDITGGLPRVAELFEARIPKDNS
HHHHHHHHHCCEEEECCCCEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCC
VIAKISGRIEFVKDYKAKRKIAIVPEEGDPIEYLIPKSKVLEVQEGDMVKRGDALISGSP
EEEEECCCHHHHHHHCCCCEEEEECCCCCCCEEECCCHHEEEECCCCCEECCCEEECCCC
NPHDILDVMGVEALAEYLVAEIQEVYRLQGVKINDKHIEVIVRQMLQKVEITDGGDTTLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHCCCCCCCCCEEC
PGEQLDYLEMMEYNAKLPKNGKPAEGRPVLLGITKASLQTRSFVSAASFQETTRVLTEAS
CCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
VQGKVDSLQGLKENVIVGRLIPAGTGAAMNRVRVTASSKDAALRAAMRVANQEHLIAPRT
HCCCHHHHHHHHHCCEEEEEECCCCCCHHCEEEEEECCCHHHHHHHHHHCCCCCEECCCC
AAEEHAAELAQGPEAAIGDDPLGKVQGEDFTTDDVMVEERPEGASEE
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA