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The map label for this gene is flp [H]

Identifier: 103486950

GI number: 103486950

Start: 1522028

End: 1524001

Strand: Reverse

Name: flp [H]

Synonym: Sala_1465

Alternate gene names: 103486950

Gene position: 1524001-1522028 (Counterclockwise)

Preceding gene: 103486953

Following gene: 103486949

Centisome position: 45.56

GC content: 65.15

Gene sequence:

>1974_bases
ATGCGTTTCATCCGCAAGATGATGATCGGACTCACGGCATTGGCCGCGCTGCCTTTGGCGGCGCAAGGCCCTGTGCCCGC
ACCGGCCGTGAAGAAGGCCGAAGCCATGGCGCCGAAGGCGGCGTCGGCGCCCGCCGCGCTCGACGCAAAGGATCTCGAGG
CGTGGATGGACGGCTTTCTGCCCTATGCGCTCGAACGCGGACGCATTGCTGGCGCGGTCGTGGTCGTCGTTCGTGGCGAC
GAGGTTCTGCTCCAGAAGGGCTATGGTTTTGCGGACGTCGCGAAACGCGCGCCGGTGCTCCCCGAAACGACGCTTTTCCG
ACCCGGATCGGTGTCCAAGCTGATCACCTGGACGGCGGTGATGCAGCAGGTCGAGGCGGGCAAGATCGATCTCGACAGGG
ACGTCAACGCCTATCTCGATTTCAGGATTCCGCCCTTTGAGGGCAAGCCGATCACGATGCGCCACATCATGACGCACACG
GCAGGCTTCGAGGAATCGGTGCGCCACCTGATCAGCAGCGATCCCGAGGCGGTGAAGACACTGAAAGAGCTGATGCCGCT
CGCGCTGCCCGAACGGGTGTTCGCGCCCGGTACGACGCCCGCCTATTCCAATTATGCGACGGCGCTCGCGGGGTATATCG
TCGAGCGCGTGAGCGGGCAGGGGTTTGACGATTATGTCGAGAACCGGATCTTCAAGCCGCTCGGCATGACGCATTCGACC
TTTCGCCAGCCGCTGCCCGCGCGCCTCGCGCCGCATATGGCAAAGGGCTATGCCGACGTTACCGGCAAGCCGCAGCCCTT
TGAAATGGTCATCCCCGCTCCGGCGGGTGCCATGTCGGCGAGCGGCGCCGACATGGCGAAGTTCATGATCGCGCACCTGA
ACGGTGGCGGCGGGATACTGAAACCCGAAACCGCCCGGCAGATGCACGATTTCAAGGCCGCCGGCGTCGGCCCGCTCAAC
AGCATGGCGCTCGGTTTCTACGAACAATGGGTCAATGGACGCCGCGCGATCGCGCACGGTGGCGATACCGTCTGGTTCCA
CTCCTATCTCTGGCTGTTCCCCGAATCCGACATCGGCATTTTCCTGTCGATGAATGCGCAGGGCAGGGATGGGGCAACGG
GCGCGGTGCGCAGCGCGCTGTTTCACAAGTTCGCCGACCGCTATCTGCCGGGGCCGCCCGAAAAACCGTCGCAGGTCGAT
GCCGCGACCGCCCGCGACCATGCAAGGATGATGGTCGGCAATTATGTCAGCAGCCGCGGCTCCTTCACCAATTTCTTCAG
CCTCTTCGGTCTGCTGGGTCTGGCAACGATCTCGCTGACCGAGGACGGCAAGATCAGCGTTCCGGCGCTCGATGGCCTGG
GTGCCGGCGCCCGCGACTGGGTGGAGGTCGAACCCTTCGTTTGGCGCGACAGCGGCACGGGTGAACGGCTTGCCGCCGAG
GTCAGCGACGGTCGCGTCGTGCGCTGGAGCGTCGACCCCGGATCGCCCTTCATGGTCTTTGAACCCGCACCTTTCGGCGT
CAACGCTGCGTGGCTCAACCCCGCGCTGATCTTCGCCTTCGGGATCATCCTGCTGACGGCGCTCGCCTGGCCGGTGCGCG
CGCTGGTGCGGCGCCGCTTCAAGGCGGATTTCGCGCTCACCGGCAAATCGCTCCGCGCCTATCGCCTGTCGCGCGCCTTC
GCTTGGCTCGTGCTCGCGGCGGCGGCGGGGTGGATTGCGCTGATCGCCGCCTTTACGGCCGACATCGGCAGCATCGGCGG
CCCGCTCGACTGGCTCATCCATCTGCTACGCGTCCTGACCCCTCTGGCCGCCTTCGGCTTGCTGGCGACGGGCGGCTGGC
ACCTGTGGTTTTCGATCAAGGACAAGCGGCGCTGGACAATGAAGCTCGGCGCGGTGCTGCTGATCCTCGCCGCCGCGGTG
CTTGTCTGGGTGACACTCGCCTTTCATCTCTATGGCTTCGGGATGGTCTATTGA

Upstream 100 bases:

>100_bases
ATTATGTCCCCATTGGGTTAACTTATACTGAGTCCTTGGTAAGGGGTCGCGCGGCTTGCCGCAAGGTGTGACAGGGCGCG
CCGGACAAAAGGGGAAAGCG

Downstream 100 bases:

>100_bases
TGGCGATCCGGCGCAGCAGCGAATTGTCGCTCGACCTCCGGGTCGAGCGCTTTCCCTACCACCAGCCCTTCCGCATTTCC
GGCCATGTCTTCACCGAAAC

Product: beta-lactamase

Products: A Substituted Beta- Amino Acid. [C]

Alternate protein names: FmtA-like protein [H]

Number of amino acids: Translated: 657; Mature: 657

Protein sequence:

>657_residues
MRFIRKMMIGLTALAALPLAAQGPVPAPAVKKAEAMAPKAASAPAALDAKDLEAWMDGFLPYALERGRIAGAVVVVVRGD
EVLLQKGYGFADVAKRAPVLPETTLFRPGSVSKLITWTAVMQQVEAGKIDLDRDVNAYLDFRIPPFEGKPITMRHIMTHT
AGFEESVRHLISSDPEAVKTLKELMPLALPERVFAPGTTPAYSNYATALAGYIVERVSGQGFDDYVENRIFKPLGMTHST
FRQPLPARLAPHMAKGYADVTGKPQPFEMVIPAPAGAMSASGADMAKFMIAHLNGGGGILKPETARQMHDFKAAGVGPLN
SMALGFYEQWVNGRRAIAHGGDTVWFHSYLWLFPESDIGIFLSMNAQGRDGATGAVRSALFHKFADRYLPGPPEKPSQVD
AATARDHARMMVGNYVSSRGSFTNFFSLFGLLGLATISLTEDGKISVPALDGLGAGARDWVEVEPFVWRDSGTGERLAAE
VSDGRVVRWSVDPGSPFMVFEPAPFGVNAAWLNPALIFAFGIILLTALAWPVRALVRRRFKADFALTGKSLRAYRLSRAF
AWLVLAAAAGWIALIAAFTADIGSIGGPLDWLIHLLRVLTPLAAFGLLATGGWHLWFSIKDKRRWTMKLGAVLLILAAAV
LVWVTLAFHLYGFGMVY

Sequences:

>Translated_657_residues
MRFIRKMMIGLTALAALPLAAQGPVPAPAVKKAEAMAPKAASAPAALDAKDLEAWMDGFLPYALERGRIAGAVVVVVRGD
EVLLQKGYGFADVAKRAPVLPETTLFRPGSVSKLITWTAVMQQVEAGKIDLDRDVNAYLDFRIPPFEGKPITMRHIMTHT
AGFEESVRHLISSDPEAVKTLKELMPLALPERVFAPGTTPAYSNYATALAGYIVERVSGQGFDDYVENRIFKPLGMTHST
FRQPLPARLAPHMAKGYADVTGKPQPFEMVIPAPAGAMSASGADMAKFMIAHLNGGGGILKPETARQMHDFKAAGVGPLN
SMALGFYEQWVNGRRAIAHGGDTVWFHSYLWLFPESDIGIFLSMNAQGRDGATGAVRSALFHKFADRYLPGPPEKPSQVD
AATARDHARMMVGNYVSSRGSFTNFFSLFGLLGLATISLTEDGKISVPALDGLGAGARDWVEVEPFVWRDSGTGERLAAE
VSDGRVVRWSVDPGSPFMVFEPAPFGVNAAWLNPALIFAFGIILLTALAWPVRALVRRRFKADFALTGKSLRAYRLSRAF
AWLVLAAAAGWIALIAAFTADIGSIGGPLDWLIHLLRVLTPLAAFGLLATGGWHLWFSIKDKRRWTMKLGAVLLILAAAV
LVWVTLAFHLYGFGMVY
>Mature_657_residues
MRFIRKMMIGLTALAALPLAAQGPVPAPAVKKAEAMAPKAASAPAALDAKDLEAWMDGFLPYALERGRIAGAVVVVVRGD
EVLLQKGYGFADVAKRAPVLPETTLFRPGSVSKLITWTAVMQQVEAGKIDLDRDVNAYLDFRIPPFEGKPITMRHIMTHT
AGFEESVRHLISSDPEAVKTLKELMPLALPERVFAPGTTPAYSNYATALAGYIVERVSGQGFDDYVENRIFKPLGMTHST
FRQPLPARLAPHMAKGYADVTGKPQPFEMVIPAPAGAMSASGADMAKFMIAHLNGGGGILKPETARQMHDFKAAGVGPLN
SMALGFYEQWVNGRRAIAHGGDTVWFHSYLWLFPESDIGIFLSMNAQGRDGATGAVRSALFHKFADRYLPGPPEKPSQVD
AATARDHARMMVGNYVSSRGSFTNFFSLFGLLGLATISLTEDGKISVPALDGLGAGARDWVEVEPFVWRDSGTGERLAAE
VSDGRVVRWSVDPGSPFMVFEPAPFGVNAAWLNPALIFAFGIILLTALAWPVRALVRRRFKADFALTGKSLRAYRLSRAF
AWLVLAAAAGWIALIAAFTADIGSIGGPLDWLIHLLRVLTPLAAFGLLATGGWHLWFSIKDKRRWTMKLGAVLLILAAAV
LVWVTLAFHLYGFGMVY

Specific function: Its precise function is unknown. Has no penicillin- binding activity and is not involved in methicillin resistance [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790593, Length=198, Percent_Identity=30.8080808080808, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI87082101, Length=265, Percent_Identity=25.2830188679245, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17550934, Length=239, Percent_Identity=29.2887029288703, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI115533026, Length=204, Percent_Identity=28.4313725490196, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: 3.5.2.6 [C]

Molecular weight: Translated: 71192; Mature: 71192

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFIRKMMIGLTALAALPLAAQGPVPAPAVKKAEAMAPKAASAPAALDAKDLEAWMDGFL
CHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
PYALERGRIAGAVVVVVRGDEVLLQKGYGFADVAKRAPVLPETTLFRPGSVSKLITWTAV
HHHHHCCCEEEEEEEEEECCEEEEECCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
MQQVEAGKIDLDRDVNAYLDFRIPPFEGKPITMRHIMTHTAGFEESVRHLISSDPEAVKT
HHHHHCCCCCCCCCCCEEEEEECCCCCCCCEEHHHHHHHHCCHHHHHHHHHCCCHHHHHH
LKELMPLALPERVFAPGTTPAYSNYATALAGYIVERVSGQGFDDYVENRIFKPLGMTHST
HHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHH
FRQPLPARLAPHMAKGYADVTGKPQPFEMVIPAPAGAMSASGADMAKFMIAHLNGGGGIL
HHCCCCHHHCHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHEECCCCCCC
KPETARQMHDFKAAGVGPLNSMALGFYEQWVNGRRAIAHGGDTVWFHSYLWLFPESDIGI
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEEEEEECCCCEE
FLSMNAQGRDGATGAVRSALFHKFADRYLPGPPEKPSQVDAATARDHARMMVGNYVSSRG
EEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
SFTNFFSLFGLLGLATISLTEDGKISVPALDGLGAGARDWVEVEPFVWRDSGTGERLAAE
CHHHHHHHHHHHHHHEEEECCCCCEECCCCCCCCCCCCCCEECCCEEEECCCCCCCEEEE
VSDGRVVRWSVDPGSPFMVFEPAPFGVNAAWLNPALIFAFGIILLTALAWPVRALVRRRF
CCCCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KADFALTGKSLRAYRLSRAFAWLVLAAAAGWIALIAAFTADIGSIGGPLDWLIHLLRVLT
HCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
PLAAFGLLATGGWHLWFSIKDKRRWTMKLGAVLLILAAAVLVWVTLAFHLYGFGMVY
HHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRFIRKMMIGLTALAALPLAAQGPVPAPAVKKAEAMAPKAASAPAALDAKDLEAWMDGFL
CHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
PYALERGRIAGAVVVVVRGDEVLLQKGYGFADVAKRAPVLPETTLFRPGSVSKLITWTAV
HHHHHCCCEEEEEEEEEECCEEEEECCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
MQQVEAGKIDLDRDVNAYLDFRIPPFEGKPITMRHIMTHTAGFEESVRHLISSDPEAVKT
HHHHHCCCCCCCCCCCEEEEEECCCCCCCCEEHHHHHHHHCCHHHHHHHHHCCCHHHHHH
LKELMPLALPERVFAPGTTPAYSNYATALAGYIVERVSGQGFDDYVENRIFKPLGMTHST
HHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHH
FRQPLPARLAPHMAKGYADVTGKPQPFEMVIPAPAGAMSASGADMAKFMIAHLNGGGGIL
HHCCCCHHHCHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHEECCCCCCC
KPETARQMHDFKAAGVGPLNSMALGFYEQWVNGRRAIAHGGDTVWFHSYLWLFPESDIGI
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEEEEEECCCCEE
FLSMNAQGRDGATGAVRSALFHKFADRYLPGPPEKPSQVDAATARDHARMMVGNYVSSRG
EEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
SFTNFFSLFGLLGLATISLTEDGKISVPALDGLGAGARDWVEVEPFVWRDSGTGERLAAE
CHHHHHHHHHHHHHHEEEECCCCCEECCCCCCCCCCCCCCEECCCEEEECCCCCCCEEEE
VSDGRVVRWSVDPGSPFMVFEPAPFGVNAAWLNPALIFAFGIILLTALAWPVRALVRRRF
CCCCEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KADFALTGKSLRAYRLSRAFAWLVLAAAAGWIALIAAFTADIGSIGGPLDWLIHLLRVLT
HCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
PLAAFGLLATGGWHLWFSIKDKRRWTMKLGAVLLILAAAVLVWVTLAFHLYGFGMVY
HHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Beta-Lactam; H2O [C]

Specific reaction: A Beta-Lactam + H2O = A Substituted Beta- Amino Acid. [C]

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA