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The map label for this gene is serB [H]

Identifier: 103486953

GI number: 103486953

Start: 1526939

End: 1527823

Strand: Reverse

Name: serB [H]

Synonym: Sala_1468

Alternate gene names: 103486953

Gene position: 1527823-1526939 (Counterclockwise)

Preceding gene: 103486964

Following gene: 103486950

Centisome position: 45.67

GC content: 66.89

Gene sequence:

>885_bases
ATGTTCGTCGCGACGCTGATAGCAGCCGGAAAGCTGACCGACGAGGTGGTTCGCGAAGCGATCGACCGGCTCGACGCAAC
GGGGCACGACGTCGGCGCGCCGCACTGGCTGGATGTCGGCGATGCGGCCGACATCGTCTTTCACGGCAGTTTGGTCAGTG
CGCGCAGTGAACTGATGCTGATGGACCATGGCGCGCTCGACATCGTCGTTCAGCCGCTCGGCGATCGCACCAAGAAACTG
ATCGTCGCCGACATGGATTCGACGATGATCACGGTCGAGTGCATCGACGAGCTTGCCGATTATGCGGGGCTGAAACCGCA
GATTGCGGCGATCACCGCGCGCGCGATGAACGGCGAGCTCGATTTTCGCGCCGCGCTGGAGGAGCGCGTCGGCCTGCTCG
CGGGCATGGACGAGGCGGTGCTGGTCGAATGCCGGATGGAGCGCGTGAAACTGACGCGCGGCGCGCGGACGCTGGTGCAG
ACGATGAAGGCGCATGGCGCTCATTCGGTGCTGGTGTCGGGCGGCTTCATGCCCTTTGCCGGGCCGGTCGGCGAAGCCGT
CGGTTTCGACAAGGTGGTCGCGAACGAGCTGGAGGTCGCGGGCGGCAAGCTCACCGGCAGGGTGCTCGAACCGATCGTCG
ACAGCAGAGCGAAGCTCGAGACGCTGAAGACCGAAGCGGCGGCGCACCGCCTGCCGCTCGCCGAGACCCTGGCCGTCGGC
GACGGCGCCAACGATATTCCGATGATTACCACGGCGGGGCTCGGCATAGGCTATCATCCGCATCCCGCCGCCGCCGCGGC
GTCGGCGGCGGTGATCCGCCATCACGATCTGACCGCGCTGCTCTGGGCGCAGGGCTATCCGCGGCGCAGCTGGGTGCTCG
GATAA

Upstream 100 bases:

>100_bases
TGCGAGCGCAACCGCCAAAGCGCTCTTGCCGCTGGCGGTGGGTCCGGCGATAAGTGCCACGGGCAGCCGCGCGTTGGCGG
TCGAGAAAGAAGGAGATGCC

Downstream 100 bases:

>100_bases
AAGGAACCCGGTCAATGGCCGGGCCCGGGAGGAGTTCCGCAAGCGGAAATCCAGTGGATCGAAACCTTATTGGGCGGGCA
CGGCTGCACCGCCGTGACGA

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MFVATLIAAGKLTDEVVREAIDRLDATGHDVGAPHWLDVGDAADIVFHGSLVSARSELMLMDHGALDIVVQPLGDRTKKL
IVADMDSTMITVECIDELADYAGLKPQIAAITARAMNGELDFRAALEERVGLLAGMDEAVLVECRMERVKLTRGARTLVQ
TMKAHGAHSVLVSGGFMPFAGPVGEAVGFDKVVANELEVAGGKLTGRVLEPIVDSRAKLETLKTEAAAHRLPLAETLAVG
DGANDIPMITTAGLGIGYHPHPAAAAASAAVIRHHDLTALLWAQGYPRRSWVLG

Sequences:

>Translated_294_residues
MFVATLIAAGKLTDEVVREAIDRLDATGHDVGAPHWLDVGDAADIVFHGSLVSARSELMLMDHGALDIVVQPLGDRTKKL
IVADMDSTMITVECIDELADYAGLKPQIAAITARAMNGELDFRAALEERVGLLAGMDEAVLVECRMERVKLTRGARTLVQ
TMKAHGAHSVLVSGGFMPFAGPVGEAVGFDKVVANELEVAGGKLTGRVLEPIVDSRAKLETLKTEAAAHRLPLAETLAVG
DGANDIPMITTAGLGIGYHPHPAAAAASAAVIRHHDLTALLWAQGYPRRSWVLG
>Mature_294_residues
MFVATLIAAGKLTDEVVREAIDRLDATGHDVGAPHWLDVGDAADIVFHGSLVSARSELMLMDHGALDIVVQPLGDRTKKL
IVADMDSTMITVECIDELADYAGLKPQIAAITARAMNGELDFRAALEERVGLLAGMDEAVLVECRMERVKLTRGARTLVQ
TMKAHGAHSVLVSGGFMPFAGPVGEAVGFDKVVANELEVAGGKLTGRVLEPIVDSRAKLETLKTEAAAHRLPLAETLAVG
DGANDIPMITTAGLGIGYHPHPAAAAASAAVIRHHDLTALLWAQGYPRRSWVLG

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=182, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1790849, Length=216, Percent_Identity=45.8333333333333, Blast_Score=175, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI115534454, Length=189, Percent_Identity=34.3915343915344, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115534456, Length=189, Percent_Identity=34.3915343915344, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115534458, Length=191, Percent_Identity=34.0314136125654, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6321647, Length=300, Percent_Identity=35, Blast_Score=168, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24661601, Length=190, Percent_Identity=28.4210526315789, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 31101; Mature: 31101

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVATLIAAGKLTDEVVREAIDRLDATGHDVGAPHWLDVGDAADIVFHGSLVSARSELML
CHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCEEEECHHHHCCCCEEE
MDHGALDIVVQPLGDRTKKLIVADMDSTMITVECIDELADYAGLKPQIAAITARAMNGEL
EECCCEEEEEECCCCCCEEEEEEECCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
DFRAALEERVGLLAGMDEAVLVECRMERVKLTRGARTLVQTMKAHGAHSVLVSGGFMPFA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
GPVGEAVGFDKVVANELEVAGGKLTGRVLEPIVDSRAKLETLKTEAAAHRLPLAETLAVG
CCCHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHEEC
DGANDIPMITTAGLGIGYHPHPAAAAASAAVIRHHDLTALLWAQGYPRRSWVLG
CCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHEEEECCCCCCCCCCCC
>Mature Secondary Structure
MFVATLIAAGKLTDEVVREAIDRLDATGHDVGAPHWLDVGDAADIVFHGSLVSARSELML
CHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCEEEECHHHHCCCCEEE
MDHGALDIVVQPLGDRTKKLIVADMDSTMITVECIDELADYAGLKPQIAAITARAMNGEL
EECCCEEEEEECCCCCCEEEEEEECCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
DFRAALEERVGLLAGMDEAVLVECRMERVKLTRGARTLVQTMKAHGAHSVLVSGGFMPFA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
GPVGEAVGFDKVVANELEVAGGKLTGRVLEPIVDSRAKLETLKTEAAAHRLPLAETLAVG
CCCHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHEEC
DGANDIPMITTAGLGIGYHPHPAAAAASAAVIRHHDLTALLWAQGYPRRSWVLG
CCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]