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The map label for this gene is acrE [H]

Identifier: 103486933

GI number: 103486933

Start: 1495276

End: 1496406

Strand: Direct

Name: acrE [H]

Synonym: Sala_1448

Alternate gene names: 103486933

Gene position: 1495276-1496406 (Clockwise)

Preceding gene: 103486925

Following gene: 103486934

Centisome position: 44.7

GC content: 68.7

Gene sequence:

>1131_bases
ATGAGTCGCGTTTCTCCTCCCCGCTGCGCCCTCGGCGCCGCACTGGCCCTGCTGCTGGTCGGCTGTTCGTCCGAAGCGCC
GCCTGCGCCACCGCCTCCCGAAGTGAATATCGTCACCGTGCGCGCCCGGCCGGTGCCCAACGTCATCGAACTGCCCGGCC
GCGTCCAGGCGTATCGGACATCGGAGGTCCGGGCGCGTGTCGATGGCATCGTCGAACGCCGCCTGTTCGACGAGGGCAGT
TTTGTGCGCGCGGGCACCGCTTTGTTCCGCATCGACCCGCGACAATTGATCGCGAACGTCAACGCCGCGCGCGCGCAGCT
GGCCCGTGCCCAGGCGACCGCGGCGAATGCGCGGCAGGTGGTGGCGCGATACCAGCCGCTGCTCGCCGACCAGGCGATCG
GCAGACAGGAATATGACGCCGCGGTCGCCGCGCAGCGCACCGCCGAAGCCGACGTGCAGGCGGCGCAGGCCAATCTGGAT
TCGGCACGGTTGAACCTCGGCTATGCGACGGTGACTGCGCCGATTTCGGGGCGCGCACGCCGCGCCGAAGTAACCGAGGG
CGCGCTGGTCAGCGCAGCACAGGGCACGCTGCTCACCACGATCGAACAGATCGACCGCGTTTACGTCAATTTCGGCCAGT
CGAGTTCGGACCTGCTGGCGACGCGCCGCGACATGGGATCGGGACGGATCAGCGCGCCGCAGCTCGAAAGGGTCGAGGTG
CAGTTGATCCTCGAGGATGGCAGCGCCTATCCGGTCGTCGGCCATCTCGACTTCCTCGACCTGTCGATCGACGAGGCGAC
CGGCACCGCCGCGCTGCGCGCGGAGTTTCCGAACCCCAACGCCGCCTTGCTTCCCGGCCAGTTCGTACGCGCACGCATCT
TTGCCGGCAATCGCGCCGACGGGATGCTGATCCCGCAGCGCGCGGTCAAGCTGACCGCCGACGCCGCGAGCGTGATGGTG
CTCGATACGAAAAATGTCGCAACGCCGCGGCCGATCAAGCTCGGTGCGATGGTCGCGGGTCAGTGGGCGGTGCTCGATGG
GCTGAGACCCGGCGACCGGGTGATCGTCGACGGGCTGCAAAAGGTTCAGCCGGGCCAGCCGGTGCGCATCGCGCCGCCTG
CGAAACGCTGA

Upstream 100 bases:

>100_bases
GTCCCTTGTCGACGTTTGTAACTTAAATTACAGAGAACTGTCGGCGCACGCTTTCGCCTATAAAAACATCCCGCACAACT
GCGATTTTTCAGGGGTCAAC

Downstream 100 bases:

>100_bases
TCCGGCATGACTCCCCGCTTTTTCATCGACCGGCCCATTTTTTCCTGGGTCATCGCCATCGGCATCCTGCTCGCCGGGAT
CATCGCGCTGCGTGGGCTGC

Product: secretion protein HlyD

Products: NA

Alternate protein names: Protein envC [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MSRVSPPRCALGAALALLLVGCSSEAPPAPPPPEVNIVTVRARPVPNVIELPGRVQAYRTSEVRARVDGIVERRLFDEGS
FVRAGTALFRIDPRQLIANVNAARAQLARAQATAANARQVVARYQPLLADQAIGRQEYDAAVAAQRTAEADVQAAQANLD
SARLNLGYATVTAPISGRARRAEVTEGALVSAAQGTLLTTIEQIDRVYVNFGQSSSDLLATRRDMGSGRISAPQLERVEV
QLILEDGSAYPVVGHLDFLDLSIDEATGTAALRAEFPNPNAALLPGQFVRARIFAGNRADGMLIPQRAVKLTADAASVMV
LDTKNVATPRPIKLGAMVAGQWAVLDGLRPGDRVIVDGLQKVQPGQPVRIAPPAKR

Sequences:

>Translated_376_residues
MSRVSPPRCALGAALALLLVGCSSEAPPAPPPPEVNIVTVRARPVPNVIELPGRVQAYRTSEVRARVDGIVERRLFDEGS
FVRAGTALFRIDPRQLIANVNAARAQLARAQATAANARQVVARYQPLLADQAIGRQEYDAAVAAQRTAEADVQAAQANLD
SARLNLGYATVTAPISGRARRAEVTEGALVSAAQGTLLTTIEQIDRVYVNFGQSSSDLLATRRDMGSGRISAPQLERVEV
QLILEDGSAYPVVGHLDFLDLSIDEATGTAALRAEFPNPNAALLPGQFVRARIFAGNRADGMLIPQRAVKLTADAASVMV
LDTKNVATPRPIKLGAMVAGQWAVLDGLRPGDRVIVDGLQKVQPGQPVRIAPPAKR
>Mature_375_residues
SRVSPPRCALGAALALLLVGCSSEAPPAPPPPEVNIVTVRARPVPNVIELPGRVQAYRTSEVRARVDGIVERRLFDEGSF
VRAGTALFRIDPRQLIANVNAARAQLARAQATAANARQVVARYQPLLADQAIGRQEYDAAVAAQRTAEADVQAAQANLDS
ARLNLGYATVTAPISGRARRAEVTEGALVSAAQGTLLTTIEQIDRVYVNFGQSSSDLLATRRDMGSGRISAPQLERVEVQ
LILEDGSAYPVVGHLDFLDLSIDEATGTAALRAEFPNPNAALLPGQFVRARIFAGNRADGMLIPQRAVKLTADAASVMVL
DTKNVATPRPIKLGAMVAGQWAVLDGLRPGDRVIVDGLQKVQPGQPVRIAPPAKR

Specific function: May affect specific membrane functions, such as septum formation during cell division, and cell membrane permeability [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789665, Length=357, Percent_Identity=43.9775910364146, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1786668, Length=368, Percent_Identity=42.3913043478261, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1789929, Length=355, Percent_Identity=41.1267605633803, Blast_Score=258, Evalue=5e-70,
Organism=Escherichia coli, GI87082036, Length=341, Percent_Identity=31.3782991202346, Blast_Score=153, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39940; Mature: 39809

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVSPPRCALGAALALLLVGCSSEAPPAPPPPEVNIVTVRARPVPNVIELPGRVQAYRT
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHHHCCCCEEEEEH
SEVRARVDGIVERRLFDEGSFVRAGTALFRIDPRQLIANVNAARAQLARAQATAANARQV
HHHHHHHHHHHHHHHCCCCCEEEECEEEEEECHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VARYQPLLADQAIGRQEYDAAVAAQRTAEADVQAAQANLDSARLNLGYATVTAPISGRAR
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCEEEEEECCCCCCC
RAEVTEGALVSAAQGTLLTTIEQIDRVYVNFGQSSSDLLATRRDMGSGRISAPQLERVEV
CCCCCCCCEEECCCCHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCCCCCCCCCCEEEE
QLILEDGSAYPVVGHLDFLDLSIDEATGTAALRAEFPNPNAALLPGQFVRARIFAGNRAD
EEEEECCCCCEEEECCEEEEEEECCCCCCEEEEEECCCCCCEECCCCEEEEEEEECCCCC
GMLIPQRAVKLTADAASVMVLDTKNVATPRPIKLGAMVAGQWAVLDGLRPGDRVIVDGLQ
CEEECCHHEEEECCCEEEEEEECCCCCCCCCEEECEEECCCCCEECCCCCCCHHHHHHHH
KVQPGQPVRIAPPAKR
HCCCCCCEECCCCCCC
>Mature Secondary Structure 
SRVSPPRCALGAALALLLVGCSSEAPPAPPPPEVNIVTVRARPVPNVIELPGRVQAYRT
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHHHCCCCEEEEEH
SEVRARVDGIVERRLFDEGSFVRAGTALFRIDPRQLIANVNAARAQLARAQATAANARQV
HHHHHHHHHHHHHHHCCCCCEEEECEEEEEECHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VARYQPLLADQAIGRQEYDAAVAAQRTAEADVQAAQANLDSARLNLGYATVTAPISGRAR
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCEEEEEECCCCCCC
RAEVTEGALVSAAQGTLLTTIEQIDRVYVNFGQSSSDLLATRRDMGSGRISAPQLERVEV
CCCCCCCCEEECCCCHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCCCCCCCCCCEEEE
QLILEDGSAYPVVGHLDFLDLSIDEATGTAALRAEFPNPNAALLPGQFVRARIFAGNRAD
EEEEECCCCCEEEECCEEEEEEECCCCCCEEEEEECCCCCCEECCCCEEEEEEEECCCCC
GMLIPQRAVKLTADAASVMVLDTKNVATPRPIKLGAMVAGQWAVLDGLRPGDRVIVDGLQ
CEEECCHHEEEECCCEEEEEEECCCCCCCCCEEECEEECCCCCEECCCCCCCHHHHHHHH
KVQPGQPVRIAPPAKR
HCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1720861; 9278503 [H]