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The map label for this gene is fabH

Identifier: 103486904

GI number: 103486904

Start: 1471564

End: 1472529

Strand: Reverse

Name: fabH

Synonym: Sala_1418

Alternate gene names: 103486904

Gene position: 1472529-1471564 (Counterclockwise)

Preceding gene: 103486905

Following gene: 103486903

Centisome position: 44.02

GC content: 69.57

Gene sequence:

>966_bases
ATGACGCGCCGCGCGATCCTGAAAGGCACGGGCTCGGCGCTGCCGCGCACGCGCGTTTCCAACGCTGAGCTTGCGGAGCG
CGTCGACACCAGCGACGAATGGATCGTCGAGCGCACCGGCATCCGTTTTCGCCACATCGCCGAACCCGACGAAACGACCG
CGACGCTCGGCGCCGATGCCGCGCGGCGGGCGCTCGAGGCGGCGGGGCTCCAGCCCGCCGACATCGGCCTGATCATCGTC
GCGACGGCGACCCCCGACAACACTTTCCCGGCGAGCGCGACCAAGGTGCAGGCGCTGCTCGGCGCGCCCGACTGCATCGC
CTTTGACGTTGCGGCGGTCTGTTCGGGCTTCCTTTATGCCGTTTCGGTCGCCGACGCGATGCTGCGCACCGGCGCGGCGA
GGCACGCGCTGGTGATCGGCAGCGAGACGTTCAGCCGCATCCTGGACTGGAACGACCGCACGACCTGCGTGTTGTTCGGC
GATGGCGCGGGCGCGGTGGTGCTGTCGGCCGAAGACGTCGCCGACGATCGCGGCGTTCTGGCAACGCGGCTCCATGCCGA
GGGCCGGTATTGCGATATGCTCTATGTCGATGGCGGCCCCTCGACGACGGGCACGGTCGGCCATGTGCGGATGCAGGGGC
GCGAGGTTTTCCGTCATGCCGTCACCAACCTGGCCGCCGTGCTGGGCGAAGTGATGCGCGACGTCGGCCTCTCGGCCGAC
GACATCGACTGGGTCGTGCCGCATCAGGCGAACAAGCGCATCATCGACGCGACCGCGAAAAAGCTGGGCCTGCCTGCCGA
CCGCGTTGTCCTGACGGTGGACCAGCACGCCAACACGTCGGCCGCATCGGTGCCGCTGGCGCTCGACCTTGCCGTGCGCG
ACGGGCGCATCAAGCGCGGCGATCTCGTGGTGCTCGAAGCAATGGGCGGCGGCTTCACCTGGGGCGCTGCCGTCCTGCGC
GTGTAG

Upstream 100 bases:

>100_bases
GAGTCGCGAACTGCGTCCACCTGTGCGCCGAGCTGATCGAAAAGGATATTACGCGTCAGGTGACCGAGGATCTTGCGAAT
TTCCGCCGCGGCGACGCCGC

Downstream 100 bases:

>100_bases
GGGCCAGTCGGCGTGGGCCGACGCGATGGCACTCGTCGCGTCAACTCCTCCGTCCATCCGTTTCAGTTTGGCGGATTTAT
TCGGATTTGTTACATATAGG

Product: 3-oxoacyl-(acyl-carrier-protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MTRRAILKGTGSALPRTRVSNAELAERVDTSDEWIVERTGIRFRHIAEPDETTATLGADAARRALEAAGLQPADIGLIIV
ATATPDNTFPASATKVQALLGAPDCIAFDVAAVCSGFLYAVSVADAMLRTGAARHALVIGSETFSRILDWNDRTTCVLFG
DGAGAVVLSAEDVADDRGVLATRLHAEGRYCDMLYVDGGPSTTGTVGHVRMQGREVFRHAVTNLAAVLGEVMRDVGLSAD
DIDWVVPHQANKRIIDATAKKLGLPADRVVLTVDQHANTSAASVPLALDLAVRDGRIKRGDLVVLEAMGGGFTWGAAVLR
V

Sequences:

>Translated_321_residues
MTRRAILKGTGSALPRTRVSNAELAERVDTSDEWIVERTGIRFRHIAEPDETTATLGADAARRALEAAGLQPADIGLIIV
ATATPDNTFPASATKVQALLGAPDCIAFDVAAVCSGFLYAVSVADAMLRTGAARHALVIGSETFSRILDWNDRTTCVLFG
DGAGAVVLSAEDVADDRGVLATRLHAEGRYCDMLYVDGGPSTTGTVGHVRMQGREVFRHAVTNLAAVLGEVMRDVGLSAD
DIDWVVPHQANKRIIDATAKKLGLPADRVVLTVDQHANTSAASVPLALDLAVRDGRIKRGDLVVLEAMGGGFTWGAAVLR
V
>Mature_320_residues
TRRAILKGTGSALPRTRVSNAELAERVDTSDEWIVERTGIRFRHIAEPDETTATLGADAARRALEAAGLQPADIGLIIVA
TATPDNTFPASATKVQALLGAPDCIAFDVAAVCSGFLYAVSVADAMLRTGAARHALVIGSETFSRILDWNDRTTCVLFGD
GAGAVVLSAEDVADDRGVLATRLHAEGRYCDMLYVDGGPSTTGTVGHVRMQGREVFRHAVTNLAAVLGEVMRDVGLSADD
IDWVVPHQANKRIIDATAKKLGLPADRVVLTVDQHANTSAASVPLALDLAVRDGRIKRGDLVVLEAMGGGFTWGAAVLRV

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family

Homologues:

Organism=Escherichia coli, GI1787333, Length=313, Percent_Identity=53.9936102236422, Blast_Score=333, Evalue=7e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABH_SPHAL (Q1GT90)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_616465.1
- ProteinModelPortal:   Q1GT90
- SMR:   Q1GT90
- GeneID:   4081735
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_1418
- NMPDR:   fig|317655.9.peg.1351
- HOGENOM:   HBG649927
- OMA:   NDYENTS
- ProtClustDB:   CLSK844009
- BioCyc:   SALA317655:SALA_1418-MONOMER
- BRENDA:   2.3.1.41
- GO:   GO:0005737
- HAMAP:   MF_01815
- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038
- Gene3D:   G3DSA:3.40.47.10
- TIGRFAMs:   TIGR00747

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C; SSF53901 Thiolase-like

EC number: =2.3.1.41

Molecular weight: Translated: 33876; Mature: 33745

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: ACT_SITE 114-114 ACT_SITE 248-248 ACT_SITE 278-278

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRAILKGTGSALPRTRVSNAELAERVDTSDEWIVERTGIRFRHIAEPDETTATLGADA
CCCCEEECCCCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCEEEEECCCCCCHHHHCHHH
ARRALEAAGLQPADIGLIIVATATPDNTFPASATKVQALLGAPDCIAFDVAAVCSGFLYA
HHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VSVADAMLRTGAARHALVIGSETFSRILDWNDRTTCVLFGDGAGAVVLSAEDVADDRGVL
HHHHHHHHHCCCCCEEEEECCHHHHHHHCCCCCEEEEEEECCCCEEEEEHHHCCCCCCEE
ATRLHAEGRYCDMLYVDGGPSTTGTVGHVRMQGREVFRHAVTNLAAVLGEVMRDVGLSAD
EEEEECCCCEEEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DIDWVVPHQANKRIIDATAKKLGLPADRVVLTVDQHANTSAASVPLALDLAVRDGRIKRG
CCCEECCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEEEECCCEECC
DLVVLEAMGGGFTWGAAVLRV
CEEEEEECCCCEEHHHHEECC
>Mature Secondary Structure 
TRRAILKGTGSALPRTRVSNAELAERVDTSDEWIVERTGIRFRHIAEPDETTATLGADA
CCCEEECCCCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCEEEEECCCCCCHHHHCHHH
ARRALEAAGLQPADIGLIIVATATPDNTFPASATKVQALLGAPDCIAFDVAAVCSGFLYA
HHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VSVADAMLRTGAARHALVIGSETFSRILDWNDRTTCVLFGDGAGAVVLSAEDVADDRGVL
HHHHHHHHHCCCCCEEEEECCHHHHHHHCCCCCEEEEEEECCCCEEEEEHHHCCCCCCEE
ATRLHAEGRYCDMLYVDGGPSTTGTVGHVRMQGREVFRHAVTNLAAVLGEVMRDVGLSAD
EEEEECCCCEEEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DIDWVVPHQANKRIIDATAKKLGLPADRVVLTVDQHANTSAASVPLALDLAVRDGRIKRG
CCCEECCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEEEECCCEECC
DLVVLEAMGGGFTWGAAVLRV
CEEEEEECCCCEEHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA