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The map label for this gene is pntB [H]

Identifier: 103486867

GI number: 103486867

Start: 1436718

End: 1438199

Strand: Reverse

Name: pntB [H]

Synonym: Sala_1381

Alternate gene names: 103486867

Gene position: 1438199-1436718 (Counterclockwise)

Preceding gene: 103486868

Following gene: 103486866

Centisome position: 42.99

GC content: 65.25

Gene sequence:

>1482_bases
ATGGATTTCCAGCCCATCCTTGCCGCCGCGGCCGGCGGCCACGGCGCGGTGAACCCGTGGGCGGCGATCGCCTATCTCGT
GTCGGGCGTCTTCTTCATCCTCGCGCTGCGCGGCCTGTCGTCGCCGGCGTCGTCGCAGCGCGGCAACCGCTTCGGCATGG
CGGGGATGACGATCGCGGTCGTCACCACGCTGTTGATGCATGTCCCCCGCCTCGACGGCGGAGCGCTCGACAGCGTGGCG
TTGACCGAAATCCTTGTCGCCATCGGCATCGGCGCGGTGATCGGCATCGTCATGGCGCGGCGCATCGCGATGACCGCGAT
GCCGCAGCTTGTCGCGGCGTTCCACAGCCTCGTCGGCCTCGCCGCCGTGGCGGTCGCGGCGGCGGCCTATCTCAATCCGC
AGGCGTTCGGCATCGCCGATGCCGCGGGACAGATCTTCACGGTCAGCCGTATCGAAATGGGCCTCGGCGTCGCAATCGGC
GCGATCACCTTTTCGGGATCGGTCATCGCCTTCCTCAAGCTCAACGGCAATATGTCGGGCGCGCCGATCCTGCTGCCCGC
GCGGCATGTCATCAATCTGGGCACGCTCGCCGCGATCATCGGCCTCGTCGCCTATTTCACCTTCGACCAGTCGCCATGGG
TATTCTGGACCGTCACGGCGCTCAGCTTCCTCATCGGCTTCCTGCTCATCATCCCGATTGGCGGGGCGGACATGCCGGTC
GTCGTGTCGATGCTCAACAGCTATTCGGGCTGGGCCGCCGCGGCGATGGGCTTCACCCTCGGCAACACCGCGATGATCAT
CACCGGCGCGCTCGTCGGTTCGTCGGGTGCGATCCTGTCGTACATCATGTGCCGCGCGATGAACCGCAGCTTCATCAGCG
TGATCGCGGGCGGCTTTGGCGCCGACGCGGCGGCGGGCGCGGGCGGTGCGAAGGAACAGCGCCCGTGGAAGCCGGGCAGC
GCCGACGACGCCGCTTTCCTGATGAGCCAGGCCGAAAATGTCATCATCGTTCCCGGTTACGGCATGGCGGTGGCGCAGGC
GCAGCACGCGCTCAGGGAAATGGCCGACCTGCTCAAGAAGGAAGGCGTCAACGTCAAATATGCGATCCACCCTGTCGCGG
GGCGGATGCCTGGGCATATGAACGTGCTGCTCGCCGAGGCGAATGTGCCCTATGACGAGGTGTTCGAACTGGAAGACATC
AATGGCGAGTTCGCCCAGTGCGACGTCGCCTTCGTCATCGGGGCGAACGACGTCACCAACCCGGCGGCCAAGACCGACAA
GAGTTCGCCGATTTACGGGATGCCGGTGCTCGACGTCGAAAAGGCGAAGACCGTGTTGTTCGTGAAGCGCTCGATGGGCG
GGGTCGGCTATGCCGGCGTCGACAATGATGTGTTCTACATGGACCAGACGATGATGCTGCTCGGCGACGCCAAGAAAATG
ACCGATGATATCGTCAAGGCGCTGAGCGGCAGCGGGCACTGA

Upstream 100 bases:

>100_bases
CTGGGCCTTGCGGCGGTCGTGATGGCGAGCGTCAATATCTTCGGCGGTTTCGCGGTCACCGCGCGCATGCTGGCGATGTA
CAAGAAGAAGGAGCGCTGAG

Downstream 100 bases:

>100_bases
CCCCACAACCATTGACCCGAATCGTCATCCCGGCGAAGGCCGGGATCTCGACCTCGCGTTGGATAGCAACGTCGAGACCC
CGGCCTTCGCCGGGGTGACG

Product: NAD(P) transhydrogenase, beta subunit

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MDFQPILAAAAGGHGAVNPWAAIAYLVSGVFFILALRGLSSPASSQRGNRFGMAGMTIAVVTTLLMHVPRLDGGALDSVA
LTEILVAIGIGAVIGIVMARRIAMTAMPQLVAAFHSLVGLAAVAVAAAAYLNPQAFGIADAAGQIFTVSRIEMGLGVAIG
AITFSGSVIAFLKLNGNMSGAPILLPARHVINLGTLAAIIGLVAYFTFDQSPWVFWTVTALSFLIGFLLIIPIGGADMPV
VVSMLNSYSGWAAAAMGFTLGNTAMIITGALVGSSGAILSYIMCRAMNRSFISVIAGGFGADAAAGAGGAKEQRPWKPGS
ADDAAFLMSQAENVIIVPGYGMAVAQAQHALREMADLLKKEGVNVKYAIHPVAGRMPGHMNVLLAEANVPYDEVFELEDI
NGEFAQCDVAFVIGANDVTNPAAKTDKSSPIYGMPVLDVEKAKTVLFVKRSMGGVGYAGVDNDVFYMDQTMMLLGDAKKM
TDDIVKALSGSGH

Sequences:

>Translated_493_residues
MDFQPILAAAAGGHGAVNPWAAIAYLVSGVFFILALRGLSSPASSQRGNRFGMAGMTIAVVTTLLMHVPRLDGGALDSVA
LTEILVAIGIGAVIGIVMARRIAMTAMPQLVAAFHSLVGLAAVAVAAAAYLNPQAFGIADAAGQIFTVSRIEMGLGVAIG
AITFSGSVIAFLKLNGNMSGAPILLPARHVINLGTLAAIIGLVAYFTFDQSPWVFWTVTALSFLIGFLLIIPIGGADMPV
VVSMLNSYSGWAAAAMGFTLGNTAMIITGALVGSSGAILSYIMCRAMNRSFISVIAGGFGADAAAGAGGAKEQRPWKPGS
ADDAAFLMSQAENVIIVPGYGMAVAQAQHALREMADLLKKEGVNVKYAIHPVAGRMPGHMNVLLAEANVPYDEVFELEDI
NGEFAQCDVAFVIGANDVTNPAAKTDKSSPIYGMPVLDVEKAKTVLFVKRSMGGVGYAGVDNDVFYMDQTMMLLGDAKKM
TDDIVKALSGSGH
>Mature_493_residues
MDFQPILAAAAGGHGAVNPWAAIAYLVSGVFFILALRGLSSPASSQRGNRFGMAGMTIAVVTTLLMHVPRLDGGALDSVA
LTEILVAIGIGAVIGIVMARRIAMTAMPQLVAAFHSLVGLAAVAVAAAAYLNPQAFGIADAAGQIFTVSRIEMGLGVAIG
AITFSGSVIAFLKLNGNMSGAPILLPARHVINLGTLAAIIGLVAYFTFDQSPWVFWTVTALSFLIGFLLIIPIGGADMPV
VVSMLNSYSGWAAAAMGFTLGNTAMIITGALVGSSGAILSYIMCRAMNRSFISVIAGGFGADAAAGAGGAKEQRPWKPGS
ADDAAFLMSQAENVIIVPGYGMAVAQAQHALREMADLLKKEGVNVKYAIHPVAGRMPGHMNVLLAEANVPYDEVFELEDI
NGEFAQCDVAFVIGANDVTNPAAKTDKSSPIYGMPVLDVEKAKTVLFVKRSMGGVGYAGVDNDVFYMDQTMMLLGDAKKM
TDDIVKALSGSGH

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=466, Percent_Identity=47.6394849785408, Blast_Score=388, Evalue=1e-108,
Organism=Homo sapiens, GI122939153, Length=466, Percent_Identity=47.6394849785408, Blast_Score=388, Evalue=1e-108,
Organism=Escherichia coli, GI1787886, Length=469, Percent_Identity=51.8123667377399, Blast_Score=442, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17550456, Length=479, Percent_Identity=44.6764091858038, Blast_Score=366, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 51051; Mature: 51051

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFQPILAAAAGGHGAVNPWAAIAYLVSGVFFILALRGLSSPASSQRGNRFGMAGMTIAV
CCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
VTTLLMHVPRLDGGALDSVALTEILVAIGIGAVIGIVMARRIAMTAMPQLVAAFHSLVGL
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVAVAAAAYLNPQAFGIADAAGQIFTVSRIEMGLGVAIGAITFSGSVIAFLKLNGNMSG
HHHHHHHHHHCCCCCCCCHHCCCCEEEEEHHHHCCCEEEEEEEECCCEEEEEEECCCCCC
APILLPARHVINLGTLAAIIGLVAYFTFDQSPWVFWTVTALSFLIGFLLIIPIGGADMPV
CEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCHHH
VVSMLNSYSGWAAAAMGFTLGNTAMIITGALVGSSGAILSYIMCRAMNRSFISVIAGGFG
HHHHHHCCCCHHHHHHHHCCCCCEEEEEEEHCCCCCHHHHHHHHHHHCHHHHHHHHCCCC
ADAAAGAGGAKEQRPWKPGSADDAAFLMSQAENVIIVPGYGMAVAQAQHALREMADLLKK
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHH
EGVNVKYAIHPVAGRMPGHMNVLLAEANVPYDEVFELEDINGEFAQCDVAFVIGANDVTN
CCCCEEEEEEECCCCCCCCEEEEEEECCCCHHHHEEEECCCCCEEEEEEEEEECCCCCCC
PAAKTDKSSPIYGMPVLDVEKAKTVLFVKRSMGGVGYAGVDNDVFYMDQTMMLLGDAKKM
CCCCCCCCCCEECCCCCCHHHHHEEEEEECCCCCCEECCCCCCEEEECCHHHHHCCHHHH
TDDIVKALSGSGH
HHHHHHHHCCCCC
>Mature Secondary Structure
MDFQPILAAAAGGHGAVNPWAAIAYLVSGVFFILALRGLSSPASSQRGNRFGMAGMTIAV
CCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
VTTLLMHVPRLDGGALDSVALTEILVAIGIGAVIGIVMARRIAMTAMPQLVAAFHSLVGL
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVAVAAAAYLNPQAFGIADAAGQIFTVSRIEMGLGVAIGAITFSGSVIAFLKLNGNMSG
HHHHHHHHHHCCCCCCCCHHCCCCEEEEEHHHHCCCEEEEEEEECCCEEEEEEECCCCCC
APILLPARHVINLGTLAAIIGLVAYFTFDQSPWVFWTVTALSFLIGFLLIIPIGGADMPV
CEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCHHH
VVSMLNSYSGWAAAAMGFTLGNTAMIITGALVGSSGAILSYIMCRAMNRSFISVIAGGFG
HHHHHHCCCCHHHHHHHHCCCCCEEEEEEEHCCCCCHHHHHHHHHHHCHHHHHHHHCCCC
ADAAAGAGGAKEQRPWKPGSADDAAFLMSQAENVIIVPGYGMAVAQAQHALREMADLLKK
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHH
EGVNVKYAIHPVAGRMPGHMNVLLAEANVPYDEVFELEDINGEFAQCDVAFVIGANDVTN
CCCCEEEEEEECCCCCCCCEEEEEEECCCCHHHHEEEECCCCCEEEEEEEEEECCCCCCC
PAAKTDKSSPIYGMPVLDVEKAKTVLFVKRSMGGVGYAGVDNDVFYMDQTMMLLGDAKKM
CCCCCCCCCCEECCCCCCHHHHHEEEEEECCCCCCEECCCCCCEEEECCHHHHHCCHHHH
TDDIVKALSGSGH
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]