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The map label for this gene is lrp [H]

Identifier: 103486847

GI number: 103486847

Start: 1418635

End: 1419138

Strand: Reverse

Name: lrp [H]

Synonym: Sala_1361

Alternate gene names: 103486847

Gene position: 1419138-1418635 (Counterclockwise)

Preceding gene: 103486851

Following gene: 103486846

Centisome position: 42.42

GC content: 57.94

Gene sequence:

>504_bases
ATGCGCTATGGATTGCAAAGATGGGCCGTTTTTAGTTATATTATGCAATACATGGTCAAAATTGACGCCATAGGCCGCAA
GATATTGCATGAGTTGTCGCGCGACGGACGAATCTCGAACCTCGAGCTTGCCGATCGCGTCGGGCTGTCGCCCTCGGCGT
GCCTGCGCCGCGTGCAGGAACTCGAACGCAGCGGCGTGATCAAGGGTTATCGCGCGGTGATCGACCCCGCAAAGCTCGGT
TTGACTTTCCTTGCCTATGTCACCGTCGGCCTGTCGTCGCACACCAAGAAGTCGCAGGCCGATTTCGAGGCGGCGATGGC
AGAAGCGCCCGAGGTGCGCGAATGCCACAATATCACCGGCACCATCGAATATCTGTTGCGCGTCGAGACCGAGGATCTGG
CGAGCTACAAGCATTTCCATACCGAGGTGCTCGGTGTCCTGCCGCAGGTGCATTCGATCACCACCTATGTCCTGATGGAT
TCGCCGAAGGACGAGCGGGCCTGA

Upstream 100 bases:

>100_bases
CATCATGTTGTTCGGCCCCGGCGTGATCGACGAGACAAGCGCGAAGGCAGAGAGTGCGGCGAGGGTGGTCTGGTTCATGG
ACGCAATATAATGCGCTTCG

Downstream 100 bases:

>100_bases
TGGTCATTGCTTCGCTTCGCTCCTCGCAATGACGGGGGGAGAGGTTGAACACTGTGCCCCTCCACCGCATATCGGTTTCA
TGCCGAAACTTTCGTTCCTC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MRYGLQRWAVFSYIMQYMVKIDAIGRKILHELSRDGRISNLELADRVGLSPSACLRRVQELERSGVIKGYRAVIDPAKLG
LTFLAYVTVGLSSHTKKSQADFEAAMAEAPEVRECHNITGTIEYLLRVETEDLASYKHFHTEVLGVLPQVHSITTYVLMD
SPKDERA

Sequences:

>Translated_167_residues
MRYGLQRWAVFSYIMQYMVKIDAIGRKILHELSRDGRISNLELADRVGLSPSACLRRVQELERSGVIKGYRAVIDPAKLG
LTFLAYVTVGLSSHTKKSQADFEAAMAEAPEVRECHNITGTIEYLLRVETEDLASYKHFHTEVLGVLPQVHSITTYVLMD
SPKDERA
>Mature_167_residues
MRYGLQRWAVFSYIMQYMVKIDAIGRKILHELSRDGRISNLELADRVGLSPSACLRRVQELERSGVIKGYRAVIDPAKLG
LTFLAYVTVGLSSHTKKSQADFEAAMAEAPEVRECHNITGTIEYLLRVETEDLASYKHFHTEVLGVLPQVHSITTYVLMD
SPKDERA

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=143, Percent_Identity=41.958041958042, Blast_Score=125, Evalue=1e-30,
Organism=Escherichia coli, GI87081742, Length=143, Percent_Identity=30.7692307692308, Blast_Score=88, Evalue=3e-19,
Organism=Escherichia coli, GI1790182, Length=145, Percent_Identity=26.2068965517241, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 18870; Mature: 18870

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYGLQRWAVFSYIMQYMVKIDAIGRKILHELSRDGRISNLELADRVGLSPSACLRRVQE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHH
LERSGVIKGYRAVIDPAKLGLTFLAYVTVGLSSHTKKSQADFEAAMAEAPEVRECHNITG
HHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHH
TIEYLLRVETEDLASYKHFHTEVLGVLPQVHSITTYVLMDSPKDERA
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCC
>Mature Secondary Structure
MRYGLQRWAVFSYIMQYMVKIDAIGRKILHELSRDGRISNLELADRVGLSPSACLRRVQE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHH
LERSGVIKGYRAVIDPAKLGLTFLAYVTVGLSSHTKKSQADFEAAMAEAPEVRECHNITG
HHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHH
TIEYLLRVETEDLASYKHFHTEVLGVLPQVHSITTYVLMDSPKDERA
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]