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The map label for this gene is birA [H]

Identifier: 103486781

GI number: 103486781

Start: 1354166

End: 1354966

Strand: Reverse

Name: birA [H]

Synonym: Sala_1295

Alternate gene names: 103486781

Gene position: 1354966-1354166 (Counterclockwise)

Preceding gene: 103486782

Following gene: 103486780

Centisome position: 40.51

GC content: 68.29

Gene sequence:

>801_bases
TTGGCTGTTGGCGGTTGGTTATCTGTTCATCCCGGCGCTTGCGGTGGCTTCGGCGCACGCCGCATCGGTGCTGTTCTGAT
CCCGCCGATCGAGCGTATCGCGCAGACAGGTTCGACCAATGCCGACCTGCTGGCGCGGCTGGCGGGCGGCGAGCATGTCG
GCGAGGGTCACTGGCTGGTCGCCGACCGTCAGACCGCCGGGCGCGGGCGCCTGGGGCGCAGTTGGAACGACGGGCAGGGC
AATTTCATGGGGTCGACGGTCGTTCACCTGGCCGTCGGCGATCCGTCGGCGGCGACGCTGGCGCTTGTTGCCGGGGTTGC
GCTTGCCAGAACCGTCGCGGCGCTCGCGCCCGATAGCGGCGCGCAGCTCAAATGGCCGAACGACCTGCTGGTGGATGGCG
CCAAATGCGCCGGCATATTGATGGAGCGCATCGGCGATTCGGTGGTGATCGGTATCGGTGTCAATCTCACCAGCGCGCCC
GAACTGCCCGATCGTCCGACCGCAACGCTGTCCAGCAACGGCGCGGCAATCGACCGCGACCATTTTGCGGGTGCGCTGGG
CATCGCGATGATCGACGCGCTGCGGACCTGGCGGCAGGAGGGCGTCGCGAGCATCCTGCGCGCCTGGCTGCCGTTCGCGC
ACCCCGTCGGCACGCCGCTGCGCGTTTCGGAGCAGGGCATCGACGGCTTTTTCGACGGGCTTGCCGAGGATGGTGCGCTG
CGCTTGCGCCGCGAGGGCGGGGAGACCATGCTGATTCATGCGGGCGACGTCGAACTTCGCCGCCCGGTGGTTGAAGGATA
A

Upstream 100 bases:

>100_bases
TCGCGATCATCAAGACGATGTATTTCGATGATAAATCTGACGTCGAGGTGACAGGCGGCGGCAATGCCGTCGAGGGCACG
ATCGTCGCGGCGAGCGCGCT

Downstream 100 bases:

>100_bases
CGCCATGCTGCTCGCGATCGACGTCGGCAACACCAACGCCAAATTTGCGCTGTTTCGCGGGGCCGAGCTGCTCGCGCGCT
GGCGCATCGCGACCGACGAC

Product: biotin--acetyl-CoA-carboxylase ligase

Products: NA

Alternate protein names: Biotin--protein ligase [H]

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MAVGGWLSVHPGACGGFGARRIGAVLIPPIERIAQTGSTNADLLARLAGGEHVGEGHWLVADRQTAGRGRLGRSWNDGQG
NFMGSTVVHLAVGDPSAATLALVAGVALARTVAALAPDSGAQLKWPNDLLVDGAKCAGILMERIGDSVVIGIGVNLTSAP
ELPDRPTATLSSNGAAIDRDHFAGALGIAMIDALRTWRQEGVASILRAWLPFAHPVGTPLRVSEQGIDGFFDGLAEDGAL
RLRREGGETMLIHAGDVELRRPVVEG

Sequences:

>Translated_266_residues
MAVGGWLSVHPGACGGFGARRIGAVLIPPIERIAQTGSTNADLLARLAGGEHVGEGHWLVADRQTAGRGRLGRSWNDGQG
NFMGSTVVHLAVGDPSAATLALVAGVALARTVAALAPDSGAQLKWPNDLLVDGAKCAGILMERIGDSVVIGIGVNLTSAP
ELPDRPTATLSSNGAAIDRDHFAGALGIAMIDALRTWRQEGVASILRAWLPFAHPVGTPLRVSEQGIDGFFDGLAEDGAL
RLRREGGETMLIHAGDVELRRPVVEG
>Mature_265_residues
AVGGWLSVHPGACGGFGARRIGAVLIPPIERIAQTGSTNADLLARLAGGEHVGEGHWLVADRQTAGRGRLGRSWNDGQGN
FMGSTVVHLAVGDPSAATLALVAGVALARTVAALAPDSGAQLKWPNDLLVDGAKCAGILMERIGDSVVIGIGVNLTSAPE
LPDRPTATLSSNGAAIDRDHFAGALGIAMIDALRTWRQEGVASILRAWLPFAHPVGTPLRVSEQGIDGFFDGLAEDGALR
LRREGGETMLIHAGDVELRRPVVEG

Specific function: Activates biotin to form biotinyl-5'-adenylate and transfers the biotin moiety to biotin-accepting proteins [H]

COG id: COG0340

COG function: function code H; Biotin-(acetyl-CoA carboxylase) ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the biotin--protein ligase family [H]

Homologues:

Organism=Escherichia coli, GI1790408, Length=235, Percent_Identity=31.9148936170213, Blast_Score=94, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004408
- InterPro:   IPR003142
- InterPro:   IPR004143 [H]

Pfam domain/function: PF02237 BPL_C; PF03099 BPL_LipA_LipB [H]

EC number: =6.3.4.15 [H]

Molecular weight: Translated: 27545; Mature: 27414

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVGGWLSVHPGACGGFGARRIGAVLIPPIERIAQTGSTNADLLARLAGGEHVGEGHWLV
CCCCCEEEECCCCCCCCCHHHHCEEECCCHHHHHHCCCCCHHHHHHHCCCCCCCCCCEEE
ADRQTAGRGRLGRSWNDGQGNFMGSTVVHLAVGDPSAATLALVAGVALARTVAALAPDSG
EECCCCCCCCCCCCCCCCCCCEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCC
AQLKWPNDLLVDGAKCAGILMERIGDSVVIGIGVNLTSAPELPDRPTATLSSNGAAIDRD
CEEECCCHHEECCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCEECHH
HFAGALGIAMIDALRTWRQEGVASILRAWLPFAHPVGTPLRVSEQGIDGFFDGLAEDGAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCHHHHHHHCCCCCE
RLRREGGETMLIHAGDVELRRPVVEG
EEEECCCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
AVGGWLSVHPGACGGFGARRIGAVLIPPIERIAQTGSTNADLLARLAGGEHVGEGHWLV
CCCCEEEECCCCCCCCCHHHHCEEECCCHHHHHHCCCCCHHHHHHHCCCCCCCCCCEEE
ADRQTAGRGRLGRSWNDGQGNFMGSTVVHLAVGDPSAATLALVAGVALARTVAALAPDSG
EECCCCCCCCCCCCCCCCCCCEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCC
AQLKWPNDLLVDGAKCAGILMERIGDSVVIGIGVNLTSAPELPDRPTATLSSNGAAIDRD
CEEECCCHHEECCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCEECHH
HFAGALGIAMIDALRTWRQEGVASILRAWLPFAHPVGTPLRVSEQGIDGFFDGLAEDGAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCHHHHHHHCCCCCE
RLRREGGETMLIHAGDVELRRPVVEG
EEEECCCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8422400 [H]