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The map label for this gene is coaX

Identifier: 103486780

GI number: 103486780

Start: 1353376

End: 1354161

Strand: Reverse

Name: coaX

Synonym: Sala_1294

Alternate gene names: 103486780

Gene position: 1354161-1353376 (Counterclockwise)

Preceding gene: 103486781

Following gene: 103486779

Centisome position: 40.48

GC content: 62.85

Gene sequence:

>786_bases
ATGCTGCTCGCGATCGACGTCGGCAACACCAACGCCAAATTTGCGCTGTTTCGCGGGGCCGAGCTGCTCGCGCGCTGGCG
CATCGCGACCGACGACCGGCGCACCGCCGACGAATATATGGTGTGGCTCGATCAGTTGATGCGGATCGAGGGGTATGATC
GCGGCGACGTCGATGCCGTGATCATCTCGACCGTGGTGCCGCGCGCGCTGCACAATCTGCAACTACTGGCTCACAAATAT
TTCGGCGTCGATGCGCTGGTTGCCGGTCGCGAACCCGTCACATGGGGCATCGCATTGAAGGTTGACGAGCCGCAGTCGGT
CGGCGCCGACCGCGCGGTCAATGCGATCGCGGCACAGGCGGTCGAGCCCGGCAGGGACAAACTTGTGATCAGCTTCGGCA
CTGCCACGACGCTCGACCATATCGGCCCCGACGGCGCCTATCTGGGCGGCATCATTGCGCCGGGTGTCAACCTGTCGCTC
GAAGCGCTCGTCGCTGCGGCCGCCAAGCTGCCGCGCATCGCGATCGAGGCGCCCGCGAGCGCCAGCGTGATCGGGCGTAC
CACCGAAAGCCAGATGCTGATCGGCGTCTATTGGGGCTATGTCGCAATGATCGAAGGGCTGATAGCGCGCATGAAGGCGC
AGATCGGCAAGCCGCTTGTCGTGGTCGCGACCGGCGGCCTCGCGACACTTTTTCAGGAACAGGCCCATCTGTTCGATCGT
ATCGAACCCGATTTGACGCTGAACGGGCTCATGCACCTCTATAACCAAGGACAACAAAAGATATGA

Upstream 100 bases:

>100_bases
GAGGATGGTGCGCTGCGCTTGCGCCGCGAGGGCGGGGAGACCATGCTGATTCATGCGGGCGACGTCGAACTTCGCCGCCC
GGTGGTTGAAGGATAACGCC

Downstream 100 bases:

>100_bases
CGACTCCGGGCAAGGAGCTGCTTTTTCTCGCATTGGGGGGATCGGGCGAGATCGGCATGAACGCCAATCTATATGGCTGT
GACGGCAAATGGATCATGCT

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MLLAIDVGNTNAKFALFRGAELLARWRIATDDRRTADEYMVWLDQLMRIEGYDRGDVDAVIISTVVPRALHNLQLLAHKY
FGVDALVAGREPVTWGIALKVDEPQSVGADRAVNAIAAQAVEPGRDKLVISFGTATTLDHIGPDGAYLGGIIAPGVNLSL
EALVAAAAKLPRIAIEAPASASVIGRTTESQMLIGVYWGYVAMIEGLIARMKAQIGKPLVVVATGGLATLFQEQAHLFDR
IEPDLTLNGLMHLYNQGQQKI

Sequences:

>Translated_261_residues
MLLAIDVGNTNAKFALFRGAELLARWRIATDDRRTADEYMVWLDQLMRIEGYDRGDVDAVIISTVVPRALHNLQLLAHKY
FGVDALVAGREPVTWGIALKVDEPQSVGADRAVNAIAAQAVEPGRDKLVISFGTATTLDHIGPDGAYLGGIIAPGVNLSL
EALVAAAAKLPRIAIEAPASASVIGRTTESQMLIGVYWGYVAMIEGLIARMKAQIGKPLVVVATGGLATLFQEQAHLFDR
IEPDLTLNGLMHLYNQGQQKI
>Mature_261_residues
MLLAIDVGNTNAKFALFRGAELLARWRIATDDRRTADEYMVWLDQLMRIEGYDRGDVDAVIISTVVPRALHNLQLLAHKY
FGVDALVAGREPVTWGIALKVDEPQSVGADRAVNAIAAQAVEPGRDKLVISFGTATTLDHIGPDGAYLGGIIAPGVNLSL
EALVAAAAKLPRIAIEAPASASVIGRTTESQMLIGVYWGYVAMIEGLIARMKAQIGKPLVVVATGGLATLFQEQAHLFDR
IEPDLTLNGLMHLYNQGQQKI

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_SPHAL (Q1GTL4)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_616341.1
- ProteinModelPortal:   Q1GTL4
- SMR:   Q1GTL4
- GeneID:   4082586
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_1294
- NMPDR:   fig|317655.9.peg.1230
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- ProtClustDB:   PRK13318
- BioCyc:   SALA317655:SALA_1294-MONOMER
- BRENDA:   2.7.1.33
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 28093; Mature: 28093

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: ACT_SITE 110-110 BINDING 134-134 BINDING 188-188

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAIDVGNTNAKFALFRGAELLARWRIATDDRRTADEYMVWLDQLMRIEGYDRGDVDAV
CEEEEEECCCCCEEEEEECHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHH
IISTVVPRALHNLQLLAHKYFGVDALVAGREPVTWGIALKVDEPQSVGADRAVNAIAAQA
HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEEEECCCHHCCHHHHHHHHHHHH
VEPGRDKLVISFGTATTLDHIGPDGAYLGGIIAPGVNLSLEALVAAAAKLPRIAIEAPAS
CCCCCCEEEEEECCCHHHHHCCCCCHHCCCEECCCCCCHHHHHHHHHHHCCEEEEECCCC
ASVIGRTTESQMLIGVYWGYVAMIEGLIARMKAQIGKPLVVVATGGLATLFQEQAHLFDR
CCEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHH
IEPDLTLNGLMHLYNQGQQKI
CCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLLAIDVGNTNAKFALFRGAELLARWRIATDDRRTADEYMVWLDQLMRIEGYDRGDVDAV
CEEEEEECCCCCEEEEEECHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHH
IISTVVPRALHNLQLLAHKYFGVDALVAGREPVTWGIALKVDEPQSVGADRAVNAIAAQA
HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEEEECCCHHCCHHHHHHHHHHHH
VEPGRDKLVISFGTATTLDHIGPDGAYLGGIIAPGVNLSLEALVAAAAKLPRIAIEAPAS
CCCCCCEEEEEECCCHHHHHCCCCCHHCCCEECCCCCCHHHHHHHHHHHCCEEEEECCCC
ASVIGRTTESQMLIGVYWGYVAMIEGLIARMKAQIGKPLVVVATGGLATLFQEQAHLFDR
CCEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHH
IEPDLTLNGLMHLYNQGQQKI
CCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA