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The map label for this gene is fadE [H]

Identifier: 103486734

GI number: 103486734

Start: 1297874

End: 1298968

Strand: Reverse

Name: fadE [H]

Synonym: Sala_1247

Alternate gene names: 103486734

Gene position: 1298968-1297874 (Counterclockwise)

Preceding gene: 103486736

Following gene: 103486733

Centisome position: 38.83

GC content: 66.39

Gene sequence:

>1095_bases
ATGTCGATTTTGTACGACGAAGGGCAACAGGCGATCGCAACCGAATCGCGGCGGGCGCTCGAAGCCAGGGTGAGCAAAGA
CGATCTGCTCCCACTGCTCGACGCCCGTGGGCAATATCACAAGGGTTTCTGGACGACCGCGAAGGAACAGGGCTGGACCG
CGCTTGCGCTCCCCGAAGCCTTTGGCGGGCTCGCGCTTGGCCTCGTCGAGCTTGGCCTGATCGCGCATCAGGCGGGACGA
ACGTTGAGCGGCGCGCCGTTTCTGACCTCCAGCTTCGGCGCCGCCAAGGCGATCGAACATTACGGCACCGAGGCGCAGCA
ATCGAGGTGGCTCCCCGGCCTCGCCAGCGGCGATACGATCGGCGCCGTCGCCTTTGCCGCGGGCCCCGATCCCCTACCTG
CGGTGCCAGGCCTGGTCCTGCAGGACGCCGGCGTCCGTGGAACCGCATTCGCCGTTTCAGGCGGCCTTTTCGCCGATATC
GCGGTCGTGCTGGCCGATGAAGGCGGGTCGCCCGCGCTGGCGATTGTCGATCTTGCCGGCACCGAACGCCACGCGATCGA
GACGTTCGACAATAGCCGCTGCATCGCCGATCTTGTTCTTGCCAACGCACCGGCCGACATTCTGGTCACCGGCGGCCGGG
CACGCGCCGCCGCGCTGCACATATTGGCGTTGCAGGCGGTCGTGACCGCGCACGAACAGACGGGCGGTGCCGAGGCCTTG
ATGGAAATTGCGCGCGACTATGCGGTGACGCGCAAGGCGTTCGGCCAGCCGATCGGCGCGTTTCAGTCGATCAAGCATCG
CATTGCCGAACTTTACGGGCTTGTCGAACTGGCGCGCGCCAATGCCATCCATGCGGCGGCGCGCGAAGGAGTGGACGATT
TCCTTGTCGCCGCGGCGGCGGCGCGACTCTCGGCGACCGAAGCCTATGACACCGCTGCGCGCGACTGCATCCAGATCCAC
GGCGGCATCGGCGTCACCTGGGAAGCGGGGCTCCACCTCCACATGCGCCGCGCGCGGACACTGGCGCTCGAACAGGGAAG
CAGCCTCTTTTGGGAAGATGTGCTCGTCGACCAGTTGGCGGGCGAAAACGCATGA

Upstream 100 bases:

>100_bases
GCCCTTACGGCATCGTCGTCCCGTTCCATGAAATAACTTGACGTTTACGTCAACGTCGGGATGATGGCGAAGACAGGGCA
AGGGGAGAGGAAACGAGCCG

Downstream 100 bases:

>100_bases
CCGATCTCGAAACATATCGCGCCAGGGCGGCGGCCTGGTGCGAATCGATGGTGGCCGAGTTCGGAAAGGCCGCGCGCAAG
GGGCTGGGCGTCGAAGAAGA

Product: acyl-CoA dehydrogenase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MSILYDEGQQAIATESRRALEARVSKDDLLPLLDARGQYHKGFWTTAKEQGWTALALPEAFGGLALGLVELGLIAHQAGR
TLSGAPFLTSSFGAAKAIEHYGTEAQQSRWLPGLASGDTIGAVAFAAGPDPLPAVPGLVLQDAGVRGTAFAVSGGLFADI
AVVLADEGGSPALAIVDLAGTERHAIETFDNSRCIADLVLANAPADILVTGGRARAAALHILALQAVVTAHEQTGGAEAL
MEIARDYAVTRKAFGQPIGAFQSIKHRIAELYGLVELARANAIHAAAREGVDDFLVAAAAARLSATEAYDTAARDCIQIH
GGIGVTWEAGLHLHMRRARTLALEQGSSLFWEDVLVDQLAGENA

Sequences:

>Translated_364_residues
MSILYDEGQQAIATESRRALEARVSKDDLLPLLDARGQYHKGFWTTAKEQGWTALALPEAFGGLALGLVELGLIAHQAGR
TLSGAPFLTSSFGAAKAIEHYGTEAQQSRWLPGLASGDTIGAVAFAAGPDPLPAVPGLVLQDAGVRGTAFAVSGGLFADI
AVVLADEGGSPALAIVDLAGTERHAIETFDNSRCIADLVLANAPADILVTGGRARAAALHILALQAVVTAHEQTGGAEAL
MEIARDYAVTRKAFGQPIGAFQSIKHRIAELYGLVELARANAIHAAAREGVDDFLVAAAAARLSATEAYDTAARDCIQIH
GGIGVTWEAGLHLHMRRARTLALEQGSSLFWEDVLVDQLAGENA
>Mature_363_residues
SILYDEGQQAIATESRRALEARVSKDDLLPLLDARGQYHKGFWTTAKEQGWTALALPEAFGGLALGLVELGLIAHQAGRT
LSGAPFLTSSFGAAKAIEHYGTEAQQSRWLPGLASGDTIGAVAFAAGPDPLPAVPGLVLQDAGVRGTAFAVSGGLFADIA
VVLADEGGSPALAIVDLAGTERHAIETFDNSRCIADLVLANAPADILVTGGRARAAALHILALQAVVTAHEQTGGAEALM
EIARDYAVTRKAFGQPIGAFQSIKHRIAELYGLVELARANAIHAAAREGVDDFLVAAAAARLSATEAYDTAARDCIQIHG
GIGVTWEAGLHLHMRRARTLALEQGSSLFWEDVLVDQLAGENA

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=318, Percent_Identity=27.0440251572327, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI76496475, Length=343, Percent_Identity=26.8221574344023, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4557235, Length=343, Percent_Identity=26.8221574344023, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4557233, Length=320, Percent_Identity=25.625, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI87081958, Length=380, Percent_Identity=23.6842105263158, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17534899, Length=357, Percent_Identity=27.7310924369748, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17506239, Length=354, Percent_Identity=23.728813559322, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21356377, Length=338, Percent_Identity=25.4437869822485, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24646207, Length=279, Percent_Identity=26.8817204301075, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21355753, Length=343, Percent_Identity=25.9475218658892, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 37980; Mature: 37849

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILYDEGQQAIATESRRALEARVSKDDLLPLLDARGQYHKGFWTTAKEQGWTALALPEA
CCCEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHCCCEEEECHHH
FGGLALGLVELGLIAHQAGRTLSGAPFLTSSFGAAKAIEHYGTEAQQSRWLPGLASGDTI
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCHHHHHHHCCCHHHHHCCCCCCCCCCCC
GAVAFAAGPDPLPAVPGLVLQDAGVRGTAFAVSGGLFADIAVVLADEGGSPALAIVDLAG
EEEEEECCCCCCCCCCCCEEECCCCCCEEEEECCCHHHEEEEEEECCCCCCEEEEEEECC
TERHAIETFDNSRCIADLVLANAPADILVTGGRARAAALHILALQAVVTAHEQTGGAEAL
CCCHHHHHCCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHH
MEIARDYAVTRKAFGQPIGAFQSIKHRIAELYGLVELARANAIHAAAREGVDDFLVAAAA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
ARLSATEAYDTAARDCIQIHGGIGVTWEAGLHLHMRRARTLALEQGSSLFWEDVLVDQLA
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
GENA
CCCC
>Mature Secondary Structure 
SILYDEGQQAIATESRRALEARVSKDDLLPLLDARGQYHKGFWTTAKEQGWTALALPEA
CCEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHCCCEEEECHHH
FGGLALGLVELGLIAHQAGRTLSGAPFLTSSFGAAKAIEHYGTEAQQSRWLPGLASGDTI
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCHHHHHHHCCCHHHHHCCCCCCCCCCCC
GAVAFAAGPDPLPAVPGLVLQDAGVRGTAFAVSGGLFADIAVVLADEGGSPALAIVDLAG
EEEEEECCCCCCCCCCCCEEECCCCCCEEEEECCCHHHEEEEEEECCCCCCEEEEEEECC
TERHAIETFDNSRCIADLVLANAPADILVTGGRARAAALHILALQAVVTAHEQTGGAEAL
CCCHHHHHCCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHH
MEIARDYAVTRKAFGQPIGAFQSIKHRIAELYGLVELARANAIHAAAREGVDDFLVAAAA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
ARLSATEAYDTAARDCIQIHGGIGVTWEAGLHLHMRRARTLALEQGSSLFWEDVLVDQLA
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
GENA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]