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The map label for this gene is tpiA [H]

Identifier: 103486660

GI number: 103486660

Start: 1206815

End: 1207561

Strand: Reverse

Name: tpiA [H]

Synonym: Sala_1172

Alternate gene names: 103486660

Gene position: 1207561-1206815 (Counterclockwise)

Preceding gene: 103486669

Following gene: 103486659

Centisome position: 36.1

GC content: 70.15

Gene sequence:

>747_bases
ATGACGCGGCGCAAATATGTGGTCGGCAACTGGAAGATGAACGGGCTGAAGGAGGCGCTCGGCGAAGCCCGGGCGATTTT
TGCCGCCGCCGATACGCACCCCGGCGTCGACGTCGCGCTGTGCCCGCCCTTCACATTGATCGGCGCGATGGCCGCGGCAG
CGCCGGGCAAGGCGATCGGCGGACAGGATTGCCACAGCGCCGCGTCGGGCGCCTTCACCGGCTCGGTCGCGGCGCCCATG
CTTGCCGACGTCGGCGCGTCGCTTGTCATCGTCGGGCACAGCGAACGGCGCGAGGGTTGCGGCGAAAGCGACGCCGATGT
GCGCGCGAAGGCCGAGGCGGCGCTCGCCGCGGGCTTGTCGGTTATCCTCTGCGTCGGCGAACCGCGCAGCGTACGCGAGT
CGGGCGGCGCGATCGACCATGTGCTGGCGCAGGTCGCGGAATCGGTGCCGGACGCCCTCGATCCGCAGCGGTTTGCCATC
GCTTATGAGCCGATCTGGGCGATCGGCACGGGGCTGGTCCCGACCGTCGCCGACGTCGCGGCGATGCACGGCGCGATCCG
CAGCGCGCTGGCCGACCGTTTCGGCGACGCCGCACAGGCAATCCGCATCCTCTATGGCGGCTCGGTCAATGGTGACAATG
CCGCCGAACTGCTGGATACCGGCGACGTCGACGGTGCGCTCGTCGGCGGCGCCAGCCTGACCGCCGCGAAGTTCGTGCCG
ATCATCGAGGCCGCGGCCGGACTTTAA

Upstream 100 bases:

>100_bases
GCGCGAAAGGCGGCTTCGGGGGTCGCCGCACGGCTTGCCTCGCCGCGCGCTTCCCCGCTAGGGGCGGATCATCATTCGGA
TAAGCGGGAGAAGCGAGGCA

Downstream 100 bases:

>100_bases
TCCACCAATAATTTCCGTTCGCATCGAGCGAAGTCGAGATGCCCCTCGGGCGTGGGGTGATCGCGATGGGTGTCTCGACT
TCGCTCGACACGAACGGCAC

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MTRRKYVVGNWKMNGLKEALGEARAIFAAADTHPGVDVALCPPFTLIGAMAAAAPGKAIGGQDCHSAASGAFTGSVAAPM
LADVGASLVIVGHSERREGCGESDADVRAKAEAALAAGLSVILCVGEPRSVRESGGAIDHVLAQVAESVPDALDPQRFAI
AYEPIWAIGTGLVPTVADVAAMHGAIRSALADRFGDAAQAIRILYGGSVNGDNAAELLDTGDVDGALVGGASLTAAKFVP
IIEAAAGL

Sequences:

>Translated_248_residues
MTRRKYVVGNWKMNGLKEALGEARAIFAAADTHPGVDVALCPPFTLIGAMAAAAPGKAIGGQDCHSAASGAFTGSVAAPM
LADVGASLVIVGHSERREGCGESDADVRAKAEAALAAGLSVILCVGEPRSVRESGGAIDHVLAQVAESVPDALDPQRFAI
AYEPIWAIGTGLVPTVADVAAMHGAIRSALADRFGDAAQAIRILYGGSVNGDNAAELLDTGDVDGALVGGASLTAAKFVP
IIEAAAGL
>Mature_247_residues
TRRKYVVGNWKMNGLKEALGEARAIFAAADTHPGVDVALCPPFTLIGAMAAAAPGKAIGGQDCHSAASGAFTGSVAAPML
ADVGASLVIVGHSERREGCGESDADVRAKAEAALAAGLSVILCVGEPRSVRESGGAIDHVLAQVAESVPDALDPQRFAIA
YEPIWAIGTGLVPTVADVAAMHGAIRSALADRFGDAAQAIRILYGGSVNGDNAAELLDTGDVDGALVGGASLTAAKFVPI
IEAAAGL

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4507645, Length=245, Percent_Identity=42.8571428571429, Blast_Score=178, Evalue=4e-45,
Organism=Homo sapiens, GI226529917, Length=245, Percent_Identity=42.8571428571429, Blast_Score=178, Evalue=5e-45,
Organism=Escherichia coli, GI1790353, Length=252, Percent_Identity=41.2698412698413, Blast_Score=157, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI17536593, Length=246, Percent_Identity=41.869918699187, Blast_Score=176, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6320255, Length=247, Percent_Identity=42.5101214574899, Blast_Score=187, Evalue=2e-48,
Organism=Drosophila melanogaster, GI28572004, Length=246, Percent_Identity=42.2764227642276, Blast_Score=178, Evalue=2e-45,
Organism=Drosophila melanogaster, GI28572008, Length=246, Percent_Identity=42.2764227642276, Blast_Score=178, Evalue=2e-45,
Organism=Drosophila melanogaster, GI28572006, Length=246, Percent_Identity=42.2764227642276, Blast_Score=178, Evalue=2e-45,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 24852; Mature: 24721

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRKYVVGNWKMNGLKEALGEARAIFAAADTHPGVDVALCPPFTLIGAMAAAAPGKAIG
CCCCCEEEECCCHHHHHHHHHHHHEEEEECCCCCCCEEEECCCHHHHHHHHHCCCCCCCC
GQDCHSAASGAFTGSVAAPMLADVGASLVIVGHSERREGCGESDADVRAKAEAALAAGLS
CCHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCE
VILCVGEPRSVRESGGAIDHVLAQVAESVPDALDPQRFAIAYEPIWAIGTGLVPTVADVA
EEEEECCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHCCCCHHHHHHHH
AMHGAIRSALADRFGDAAQAIRILYGGSVNGDNAAELLDTGDVDGALVGGASLTAAKFVP
HHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCEEECCCHHHHHHHHH
IIEAAAGL
HHHHHCCC
>Mature Secondary Structure 
TRRKYVVGNWKMNGLKEALGEARAIFAAADTHPGVDVALCPPFTLIGAMAAAAPGKAIG
CCCCEEEECCCHHHHHHHHHHHHEEEEECCCCCCCEEEECCCHHHHHHHHHCCCCCCCC
GQDCHSAASGAFTGSVAAPMLADVGASLVIVGHSERREGCGESDADVRAKAEAALAAGLS
CCHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCE
VILCVGEPRSVRESGGAIDHVLAQVAESVPDALDPQRFAIAYEPIWAIGTGLVPTVADVA
EEEEECCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHCCCCHHHHHHHH
AMHGAIRSALADRFGDAAQAIRILYGGSVNGDNAAELLDTGDVDGALVGGASLTAAKFVP
HHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCEEECCCHHHHHHHHH
IIEAAAGL
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA