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The map label for this gene is pgsA [H]

Identifier: 103486642

GI number: 103486642

Start: 1189458

End: 1190045

Strand: Direct

Name: pgsA [H]

Synonym: Sala_1154

Alternate gene names: 103486642

Gene position: 1189458-1190045 (Clockwise)

Preceding gene: 103486640

Following gene: 103486643

Centisome position: 35.56

GC content: 62.41

Gene sequence:

>588_bases
ATGTCGACGGGGATCATGCTGAGCCTTCCGAACATTTTGACGCTGTCGCGAATCCTGGCGGTGCCCATCCTGCTCTTCCT
GCTGTGGCCGGGCGTGACCGAAGGGTCGCACCAGCCCAGGCCGATCGATTATGCACTGGCGTTCGGCCTCTATTGCCTGA
TGGGCATTACCGATTATTTCGACGGCTATGTCGCCCGTGCGCGCGGCACCGTGTCGCGGCTGGGCATCTTTCTTGACCCC
ATCGCCGACAAGATCATGATCGCGGCGGTGATCCTGCTGCTCGTCTTCACGCGCGACATCGACGGGTGGCACGTCATCGC
CGCGCTTGTCATCCTGCTGCGCGAAATCATCGTGTCGGGGCTGCGCGAGTTTCTTGCGACCTTGCAGGTGTCGATGCCGG
TGACGCAGCTTGCCAAATGGAAAACGACCTTCCAGCTTGTCGCCTTTGGCGCGCTGATCCTTGCGGGGGCGCTGCCCGCA
ATGGCGTGGATCAAGACGGTCGGGCTGGCGTCGTTGTGGGGGGCGGCGGTGCTGACGCTGGTAACCGGCTGGGATTATCT
GCGCGTCGGCCTGAAGCATATGGACTGA

Upstream 100 bases:

>100_bases
TTCAACTATGTCGGTTCGCACGCATTTCGCGGGCAACAGGTTGTCGCCGGGGGGGCTTATCGGCTAGGGCGGTCGGGGTC
AAAGGTCATTTTGACCGGCC

Downstream 100 bases:

>100_bases
TGCGGCTCGATCTCGCCTATTTCGCCTGGGTGCGCGAGCGGATGGGGATGGCGGGCGAGACGGTCGAACTGCCGCCCGGA
ATCGCCGATGTCGCGGCGCT

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MSTGIMLSLPNILTLSRILAVPILLFLLWPGVTEGSHQPRPIDYALAFGLYCLMGITDYFDGYVARARGTVSRLGIFLDP
IADKIMIAAVILLLVFTRDIDGWHVIAALVILLREIIVSGLREFLATLQVSMPVTQLAKWKTTFQLVAFGALILAGALPA
MAWIKTVGLASLWGAAVLTLVTGWDYLRVGLKHMD

Sequences:

>Translated_195_residues
MSTGIMLSLPNILTLSRILAVPILLFLLWPGVTEGSHQPRPIDYALAFGLYCLMGITDYFDGYVARARGTVSRLGIFLDP
IADKIMIAAVILLLVFTRDIDGWHVIAALVILLREIIVSGLREFLATLQVSMPVTQLAKWKTTFQLVAFGALILAGALPA
MAWIKTVGLASLWGAAVLTLVTGWDYLRVGLKHMD
>Mature_194_residues
STGIMLSLPNILTLSRILAVPILLFLLWPGVTEGSHQPRPIDYALAFGLYCLMGITDYFDGYVARARGTVSRLGIFLDPI
ADKIMIAAVILLLVFTRDIDGWHVIAALVILLREIIVSGLREFLATLQVSMPVTQLAKWKTTFQLVAFGALILAGALPAM
AWIKTVGLASLWGAAVLTLVTGWDYLRVGLKHMD

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=185, Percent_Identity=34.5945945945946, Blast_Score=97, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6320059, Length=172, Percent_Identity=31.9767441860465, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21322; Mature: 21191

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTGIMLSLPNILTLSRILAVPILLFLLWPGVTEGSHQPRPIDYALAFGLYCLMGITDYF
CCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DGYVARARGTVSRLGIFLDPIADKIMIAAVILLLVFTRDIDGWHVIAALVILLREIIVSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LREFLATLQVSMPVTQLAKWKTTFQLVAFGALILAGALPAMAWIKTVGLASLWGAAVLTL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTGWDYLRVGLKHMD
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
STGIMLSLPNILTLSRILAVPILLFLLWPGVTEGSHQPRPIDYALAFGLYCLMGITDYF
CCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DGYVARARGTVSRLGIFLDPIADKIMIAAVILLLVFTRDIDGWHVIAALVILLREIIVSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LREFLATLQVSMPVTQLAKWKTTFQLVAFGALILAGALPAMAWIKTVGLASLWGAAVLTL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTGWDYLRVGLKHMD
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA