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The map label for this gene is trpF [H]

Identifier: 103486554

GI number: 103486554

Start: 1098420

End: 1099061

Strand: Reverse

Name: trpF [H]

Synonym: Sala_1065

Alternate gene names: 103486554

Gene position: 1099061-1098420 (Counterclockwise)

Preceding gene: 103486555

Following gene: 103486553

Centisome position: 32.86

GC content: 64.64

Gene sequence:

>642_bases
ATGAGACCAACAATGTCCCCTCTCGTCAAAATCTGCGGCCTTACCACGCCTGAAAGCGTCGATGCCGCCATCCGCCTCGG
CGCGACGCACATCGGCCTTGTGCATTATGAGCCAAGCCAGCGGCACGTCGACCTCAGGACCGCGGCCGAGCTCCGCAAGC
GCGCGGGTCCGCACGTCAAGGTCGCGCTGCTGCTCGTCAACGCCTCGCAGCAACTGACCGGCGAGGCGCTTAGCATGGTG
CGCCCCGACATCGTCCAGTTCCACGGCAGCGAGACCCCCGAATGGCTGACAGTGGTCAAACGGCTGACCCCCGCCGAAAT
CTGGAAGGCGATCGGGCTCAAGGACGCCGAAACGCTGACCCGGATGCAGAAATATCACGGGATTGCCCACCGCATCCTGT
TCGACGCACCCGCCGCCGCGCTGCCCGGGGGCACCGGCACGCGCTTCGACTGGTCGCTGCTGAAAAATCACCGGCATACA
ATGGATTGGGGTATCGCAGGCGGTCTGACCCCCGCCAATGTCGCCCAGGCGATTGCCGAAACCGGCGCGCCGCTCGTCGA
TGTCTCGTCGGGCGTCGAAAGCGCGCCGGGCGTCAAGGATATGGACAAGATCGCCGCTTTCCTTAAAGCGGTCGGCAGAT
GA

Upstream 100 bases:

>100_bases
TCATTGCGAGGAGCCAAAGGCGACGAAGCAATCTCCAGCTATCGAGATTGCGCTACGCTAATAGCTGGAGATTGCTTCGC
TCCGCTCGCAATGACGTCAA

Downstream 100 bases:

>100_bases
CCACGCTGCGACCCCTCGTCCTGCGCATCGGGAAACGATGGCGCTGATCGCTTGAGACCTGCTCTTCAAGTGAATGCCCA
CCCGTAACCGATGGATATGA

Product: phosphoribosylanthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MRPTMSPLVKICGLTTPESVDAAIRLGATHIGLVHYEPSQRHVDLRTAAELRKRAGPHVKVALLLVNASQQLTGEALSMV
RPDIVQFHGSETPEWLTVVKRLTPAEIWKAIGLKDAETLTRMQKYHGIAHRILFDAPAAALPGGTGTRFDWSLLKNHRHT
MDWGIAGGLTPANVAQAIAETGAPLVDVSSGVESAPGVKDMDKIAAFLKAVGR

Sequences:

>Translated_213_residues
MRPTMSPLVKICGLTTPESVDAAIRLGATHIGLVHYEPSQRHVDLRTAAELRKRAGPHVKVALLLVNASQQLTGEALSMV
RPDIVQFHGSETPEWLTVVKRLTPAEIWKAIGLKDAETLTRMQKYHGIAHRILFDAPAAALPGGTGTRFDWSLLKNHRHT
MDWGIAGGLTPANVAQAIAETGAPLVDVSSGVESAPGVKDMDKIAAFLKAVGR
>Mature_213_residues
MRPTMSPLVKICGLTTPESVDAAIRLGATHIGLVHYEPSQRHVDLRTAAELRKRAGPHVKVALLLVNASQQLTGEALSMV
RPDIVQFHGSETPEWLTVVKRLTPAEIWKAIGLKDAETLTRMQKYHGIAHRILFDAPAAALPGGTGTRFDWSLLKNHRHT
MDWGIAGGLTPANVAQAIAETGAPLVDVSSGVESAPGVKDMDKIAAFLKAVGR

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=204, Percent_Identity=32.3529411764706, Blast_Score=82, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320210, Length=218, Percent_Identity=33.4862385321101, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 22913; Mature: 22913

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPTMSPLVKICGLTTPESVDAAIRLGATHIGLVHYEPSQRHVDLRTAAELRKRAGPHVK
CCCCHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEE
VALLLVNASQQLTGEALSMVRPDIVQFHGSETPEWLTVVKRLTPAEIWKAIGLKDAETLT
EEEEEECCCHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHCCCCHHHHH
RMQKYHGIAHRILFDAPAAALPGGTGTRFDWSLLKNHRHTMDWGIAGGLTPANVAQAIAE
HHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
TGAPLVDVSSGVESAPGVKDMDKIAAFLKAVGR
CCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRPTMSPLVKICGLTTPESVDAAIRLGATHIGLVHYEPSQRHVDLRTAAELRKRAGPHVK
CCCCHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEE
VALLLVNASQQLTGEALSMVRPDIVQFHGSETPEWLTVVKRLTPAEIWKAIGLKDAETLT
EEEEEECCCHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHCCCCHHHHH
RMQKYHGIAHRILFDAPAAALPGGTGTRFDWSLLKNHRHTMDWGIAGGLTPANVAQAIAE
HHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
TGAPLVDVSSGVESAPGVKDMDKIAAFLKAVGR
CCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA