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The map label for this gene is atsA [H]

Identifier: 103486502

GI number: 103486502

Start: 1040727

End: 1042274

Strand: Reverse

Name: atsA [H]

Synonym: Sala_1013

Alternate gene names: 103486502

Gene position: 1042274-1040727 (Counterclockwise)

Preceding gene: 103486503

Following gene: 103486501

Centisome position: 31.16

GC content: 61.82

Gene sequence:

>1548_bases
ATGCCGATCGCCCTCGCGCTGCCGCTGGCCTTCGTCGCCGCGGCGGGCGCGCAGCCCCCTGCCCGTCCGAACATCGTCTT
CATCATGTCGGACGATCATGCCTATCAGGCGATCTCGGCCTATGGGTCGGCGCTGTCGAAACTGGCGCCCACGCCGAACA
TCGACCGGATCGCCAAAAATGGCGCGATCTTCACGCAAAGCTTTGTCGGCAATTCGCTGTGCGGCCCCAGCCGCGCGACG
CTGCTCACCGGACGGCACAGCCACGCCCACGGGTTCCGGCAGAATGGCAACAGGTTCGACAACAGGGTCTGGGTCTGGCC
GCGGGCGCTGTCGCAGGCGGGCTACGCCACCGCGATGTTCGGCAAATGGCACCTCAACTATTCGCCCGAAGGCATCGGCT
TCGATGACTGGAAGGTGCTCGACGACCAGGGCGAATATTATAACCCCGACATCATCACGCCGAAGGGTCGCAGCATCGTG
GAGGGCTATGCGACCGACCTCACGACGCAATACAGCCTCGACTGGCTGAAGACCGGGCGCGACAAGTCGAAGCCCTTTGC
GATCCTGATCCACCACAAGGCGCCGCACCGCAATTTCATGCCCGCGCTGCGCCATGTGCAGAAATATCAGGGGGTGACCT
TTCCTGTCCCCGCCAGTTATTTCGACGATTATGCGGGTCGCAAGGCCGCTGCGGCGCAGGAAATGACCATCTATCGCGAC
ATGTATGAGGGGCATGACCTCAAGATGACGGTCGCGAAGGGGTCGGCCGAGCTTCGCTACAACCGCTGGCCCGGCGCCTT
CGACCGGATGACGCACACGCAACAGGCCGCATGGGACGCGCTGATGCAGGCCGACAACGACCGCATGAACGCCGCCAACC
TTTCCGGCCACGACCTCGCGATCTGGAAATATCAGCGTTACATGCAGCAATATCTGGGCACGATCGCCGCGGTCGACGAA
GGCGTCGGCGCGGTGCTCGATTATCTGGAGGACAGCGGCCTCGATCGGAACACGATCGTCGTCTATACCTCCGACCAGGG
CTTTTACCTTGGCGAACATGGCTGGTTCGACAAGCGCTTCATCTATGAAGAATCGATGCGCACGCCCTTCCTGATCCAGT
ATCCGGGACATATCCGCCCCGGTACGCGCGTCGCCGCGCCGATCCAGAATATCGACTATGCCCCGACCTTCCTCGACTAT
GCCGGGGTGAAGGGACCGGCGACGATCCAGGGGCGGTCGGTGACGCCGCTGCTTGCCGGGCGCACGCCGCCGGATTGGCG
CAAGGACGTCTATTATCATTATTATGAATTTCCGGGCTTTCATGCCGTTCGCGCGCATTACGGTGTACGCGGCGAACGCT
ACAAGCTCGTGCGCTTTTATGGCGACGATCTTGACGCATGGGAGTTTTACGACCTGAAAACCGATCCGCGGGAGATGCAC
AACCGGATCGACGATCCGGCGATGAAAGCGCCGATCGCCGCGATGAAAAAGCGGCTCGTCGAACTGCGTCGTCAATATGG
CGACGGCAGCGGACCCTCGATTTCCTGA

Upstream 100 bases:

>100_bases
GGCAGCGAGCCCGGCGCGTTCAAGCTGTGGATCGGCCCCTCGTCGGCCGAAGGATCCGAAGCCAGCTTCGAACTGACCGA
ATAGGAGAAGACCAATACGT

Downstream 100 bases:

>100_bases
ACGGGTTGCGATCGACCCGGCCCGTCGGTAGGCGCGGCGCGTGAGTCCTGAACCGCCCTCCGCCTTCGCGCCCTTTCGCT
ACCCGGCGTTCCGCGCGATC

Product: sulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 515; Mature: 514

Protein sequence:

>515_residues
MPIALALPLAFVAAAGAQPPARPNIVFIMSDDHAYQAISAYGSALSKLAPTPNIDRIAKNGAIFTQSFVGNSLCGPSRAT
LLTGRHSHAHGFRQNGNRFDNRVWVWPRALSQAGYATAMFGKWHLNYSPEGIGFDDWKVLDDQGEYYNPDIITPKGRSIV
EGYATDLTTQYSLDWLKTGRDKSKPFAILIHHKAPHRNFMPALRHVQKYQGVTFPVPASYFDDYAGRKAAAAQEMTIYRD
MYEGHDLKMTVAKGSAELRYNRWPGAFDRMTHTQQAAWDALMQADNDRMNAANLSGHDLAIWKYQRYMQQYLGTIAAVDE
GVGAVLDYLEDSGLDRNTIVVYTSDQGFYLGEHGWFDKRFIYEESMRTPFLIQYPGHIRPGTRVAAPIQNIDYAPTFLDY
AGVKGPATIQGRSVTPLLAGRTPPDWRKDVYYHYYEFPGFHAVRAHYGVRGERYKLVRFYGDDLDAWEFYDLKTDPREMH
NRIDDPAMKAPIAAMKKRLVELRRQYGDGSGPSIS

Sequences:

>Translated_515_residues
MPIALALPLAFVAAAGAQPPARPNIVFIMSDDHAYQAISAYGSALSKLAPTPNIDRIAKNGAIFTQSFVGNSLCGPSRAT
LLTGRHSHAHGFRQNGNRFDNRVWVWPRALSQAGYATAMFGKWHLNYSPEGIGFDDWKVLDDQGEYYNPDIITPKGRSIV
EGYATDLTTQYSLDWLKTGRDKSKPFAILIHHKAPHRNFMPALRHVQKYQGVTFPVPASYFDDYAGRKAAAAQEMTIYRD
MYEGHDLKMTVAKGSAELRYNRWPGAFDRMTHTQQAAWDALMQADNDRMNAANLSGHDLAIWKYQRYMQQYLGTIAAVDE
GVGAVLDYLEDSGLDRNTIVVYTSDQGFYLGEHGWFDKRFIYEESMRTPFLIQYPGHIRPGTRVAAPIQNIDYAPTFLDY
AGVKGPATIQGRSVTPLLAGRTPPDWRKDVYYHYYEFPGFHAVRAHYGVRGERYKLVRFYGDDLDAWEFYDLKTDPREMH
NRIDDPAMKAPIAAMKKRLVELRRQYGDGSGPSIS
>Mature_514_residues
PIALALPLAFVAAAGAQPPARPNIVFIMSDDHAYQAISAYGSALSKLAPTPNIDRIAKNGAIFTQSFVGNSLCGPSRATL
LTGRHSHAHGFRQNGNRFDNRVWVWPRALSQAGYATAMFGKWHLNYSPEGIGFDDWKVLDDQGEYYNPDIITPKGRSIVE
GYATDLTTQYSLDWLKTGRDKSKPFAILIHHKAPHRNFMPALRHVQKYQGVTFPVPASYFDDYAGRKAAAAQEMTIYRDM
YEGHDLKMTVAKGSAELRYNRWPGAFDRMTHTQQAAWDALMQADNDRMNAANLSGHDLAIWKYQRYMQQYLGTIAAVDEG
VGAVLDYLEDSGLDRNTIVVYTSDQGFYLGEHGWFDKRFIYEESMRTPFLIQYPGHIRPGTRVAAPIQNIDYAPTFLDYA
GVKGPATIQGRSVTPLLAGRTPPDWRKDVYYHYYEFPGFHAVRAHYGVRGERYKLVRFYGDDLDAWEFYDLKTDPREMHN
RIDDPAMKAPIAAMKKRLVELRRQYGDGSGPSIS

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI4504061, Length=451, Percent_Identity=26.3858093126386, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI71852584, Length=479, Percent_Identity=24.8434237995825, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI58743319, Length=552, Percent_Identity=24.0942028985507, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI4503899, Length=152, Percent_Identity=34.2105263157895, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI157266309, Length=145, Percent_Identity=35.8620689655172, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI189571643, Length=191, Percent_Identity=29.3193717277487, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI189571641, Length=191, Percent_Identity=29.3193717277487, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI189571638, Length=191, Percent_Identity=29.3193717277487, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI189571636, Length=191, Percent_Identity=29.3193717277487, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI39930577, Length=175, Percent_Identity=30.8571428571429, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI240255478, Length=191, Percent_Identity=27.2251308900524, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI240255483, Length=191, Percent_Identity=27.2251308900524, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI29789100, Length=191, Percent_Identity=27.2251308900524, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI146229331, Length=116, Percent_Identity=42.2413793103448, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI146229329, Length=116, Percent_Identity=42.2413793103448, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI6005990, Length=116, Percent_Identity=42.2413793103448, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI146229324, Length=116, Percent_Identity=42.2413793103448, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI71852586, Length=114, Percent_Identity=39.4736842105263, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI53831991, Length=133, Percent_Identity=34.5864661654135, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI31742482, Length=114, Percent_Identity=36.8421052631579, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI45430057, Length=185, Percent_Identity=30.2702702702703, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI59797060, Length=216, Percent_Identity=30.0925925925926, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI109389362, Length=220, Percent_Identity=25.4545454545455, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI4506919, Length=183, Percent_Identity=29.5081967213115, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1790233, Length=155, Percent_Identity=30.3225806451613, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790112, Length=182, Percent_Identity=32.4175824175824, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17568795, Length=460, Percent_Identity=25.8695652173913, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17559078, Length=126, Percent_Identity=38.8888888888889, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24647401, Length=116, Percent_Identity=43.1034482758621, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281363223, Length=262, Percent_Identity=27.0992366412214, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281366397, Length=223, Percent_Identity=30.0448430493274, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI281366395, Length=223, Percent_Identity=30.0448430493274, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24666163, Length=223, Percent_Identity=30.0448430493274, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24656835, Length=559, Percent_Identity=23.2558139534884, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24653364, Length=209, Percent_Identity=29.6650717703349, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19922168, Length=209, Percent_Identity=29.6650717703349, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24666175, Length=145, Percent_Identity=35.1724137931034, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24666109, Length=206, Percent_Identity=28.1553398058252, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 58224; Mature: 58093

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS00523 SULFATASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIALALPLAFVAAAGAQPPARPNIVFIMSDDHAYQAISAYGSALSKLAPTPNIDRIAKN
CCEEHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHCC
GAIFTQSFVGNSLCGPSRATLLTGRHSHAHGFRQNGNRFDNRVWVWPRALSQAGYATAMF
CCEEEHHHCCCCCCCCCCEEEEECCCCCCCCHHCCCCCCCCEEEECHHHHHHCCCEEEEE
GKWHLNYSPEGIGFDDWKVLDDQGEYYNPDIITPKGRSIVEGYATDLTTQYSLDWLKTGR
EEEEECCCCCCCCCCCCEEECCCCCEECCCEECCCCCHHHHHHHHCCEEHEEHHHHHCCC
DKSKPFAILIHHKAPHRNFMPALRHVQKYQGVTFPVPASYFDDYAGRKAAAAQEMTIYRD
CCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHH
MYEGHDLKMTVAKGSAELRYNRWPGAFDRMTHTQQAAWDALMQADNDRMNAANLSGHDLA
HHCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
IWKYQRYMQQYLGTIAAVDEGVGAVLDYLEDSGLDRNTIVVYTSDQGFYLGEHGWFDKRF
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEECCCCEECCCCCCCCHHE
IYEESMRTPFLIQYPGHIRPGTRVAAPIQNIDYAPTFLDYAGVKGPATIQGRSVTPLLAG
EHHHHCCCCEEEECCCCCCCCCEEECCHHCCCCCCHHHHHCCCCCCCEECCCCCCEEECC
RTPPDWRKDVYYHYYEFPGFHAVRAHYGVRGERYKLVRFYGDDLDAWEFYDLKTDPREMH
CCCCCHHHCCEEEEEECCCCEEEHHHCCCCCCEEEEEEEECCCCCCEEEEECCCCHHHHH
NRIDDPAMKAPIAAMKKRLVELRRQYGDGSGPSIS
HCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PIALALPLAFVAAAGAQPPARPNIVFIMSDDHAYQAISAYGSALSKLAPTPNIDRIAKN
CEEHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHCC
GAIFTQSFVGNSLCGPSRATLLTGRHSHAHGFRQNGNRFDNRVWVWPRALSQAGYATAMF
CCEEEHHHCCCCCCCCCCEEEEECCCCCCCCHHCCCCCCCCEEEECHHHHHHCCCEEEEE
GKWHLNYSPEGIGFDDWKVLDDQGEYYNPDIITPKGRSIVEGYATDLTTQYSLDWLKTGR
EEEEECCCCCCCCCCCCEEECCCCCEECCCEECCCCCHHHHHHHHCCEEHEEHHHHHCCC
DKSKPFAILIHHKAPHRNFMPALRHVQKYQGVTFPVPASYFDDYAGRKAAAAQEMTIYRD
CCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHH
MYEGHDLKMTVAKGSAELRYNRWPGAFDRMTHTQQAAWDALMQADNDRMNAANLSGHDLA
HHCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
IWKYQRYMQQYLGTIAAVDEGVGAVLDYLEDSGLDRNTIVVYTSDQGFYLGEHGWFDKRF
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEECCCCEECCCCCCCCHHE
IYEESMRTPFLIQYPGHIRPGTRVAAPIQNIDYAPTFLDYAGVKGPATIQGRSVTPLLAG
EHHHHCCCCEEEECCCCCCCCCEEECCHHCCCCCCHHHHHCCCCCCCEECCCCCCEEECC
RTPPDWRKDVYYHYYEFPGFHAVRAHYGVRGERYKLVRFYGDDLDAWEFYDLKTDPREMH
CCCCCHHHCCEEEEEECCCCEEEHHHCCCCCCEEEEEEEECCCCCCEEEEECCCCHHHHH
NRIDDPAMKAPIAAMKKRLVELRRQYGDGSGPSIS
HCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7744061; 10984043 [H]