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The map label for this gene is iolS [H]

Identifier: 103486448

GI number: 103486448

Start: 984054

End: 985049

Strand: Reverse

Name: iolS [H]

Synonym: Sala_0958

Alternate gene names: 103486448

Gene position: 985049-984054 (Counterclockwise)

Preceding gene: 103486449

Following gene: 103486443

Centisome position: 29.45

GC content: 66.37

Gene sequence:

>996_bases
ATGAAATATCGCACGCTCGGCCACGGCCTCACCGTTTCCGCGATCGGCATCGGCTGCATGCCGATGATCAAGGGCGGCAA
TATCCTTTATGGCGAGGCGGCCGATCTCGACGAAGCGACGCGCACCATCCACCGCGCGATCGACCTCGGCGTCACCTTTT
TCGATACCGCGCAAATCTATGGTCCGTTCAGCAACGAGGAGCTGCTGGGCGAAGCGATCCGCGGCAAGCGCGACGGCCTT
GTCATCGCCACCAAGTTCGGCTTCCGCTTCGACGGCAAGCAGATCACCGGCGTCGATGGCTCGCCGGAAAACGCGCGCAA
AAGCTGCGAAGGTTCGCTCCAGCGGCTCGGCATCGACACGATCGACCTTTTCTACCAGCACCGCGTCGATCCCGCGATCC
CGATCGAGGAGGTCGTCGGCGGGATGATGGAGTTGGTGAAGGAGGGCAAGGTGCGCCATATCGCGCTCTCCGAAGCCGGT
CCCGAAACGCTCCGCCGCGCTGCCAAGGCCGCGCCGATCACCGCGCTGCAAAGCGAGTATTCGATCTGGGAGCGCGACGT
GGAGGACGAGATCCTGCCCGTCTGCCGCGAACATGGCATCGGCTTCGTCCCCTATTCGCCGCTTGGCCGCGGTTTCCTCG
CGGGTGCGGTGCGCAGCCGCGACGAACTGCCCGAGCATGACTGGCGCCGCAACGACCCGCGCTATTCGGACGAGAATCTC
CCCGCCAACCTCGCGATCGTCGATGCCATCGGCGCGGTCGCCGACAAGCATGGCGTGTCAAAGGCGCAGGTGGCGCTCGC
CTGGCTGCTCGCGCGGGGCGAGGACATCGTCCCCATCCCCGGCACCAAGCGGCGCGCGACGATGGAGGACAGCGTCGGCG
CCGCCGACGTCACGCTGACCGCCGACGACATCGAGGCGATCGACTCCGCAGCGCCGAAGGGCGGAACCAGCGGCCCGCGC
TATGGCGAACAGGGGATGCGGATGGTGCGGCTGTAA

Upstream 100 bases:

>100_bases
TCCCCGATATATTCCGCACCGTCGGCAATGTCGTCGCCGATGTCGCCGCGACGCGCTTCGCCGCCGGCGAAGAAACGCAC
GCACCCGCAGGAGAAACGCC

Downstream 100 bases:

>100_bases
GACTTCGGCGGCAGGGCCGTTATCCCACCCAGCGCCAGACCCCTGCAACCATATAGCCCAGCGCGCCATGCGCCCAGCTC
GCCGCGAGCCAGAGGATGAT

Product: aldo/keto reductase

Products: NA

Alternate protein names: AKR11A; Vegetative protein 147; VEG147 [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MKYRTLGHGLTVSAIGIGCMPMIKGGNILYGEAADLDEATRTIHRAIDLGVTFFDTAQIYGPFSNEELLGEAIRGKRDGL
VIATKFGFRFDGKQITGVDGSPENARKSCEGSLQRLGIDTIDLFYQHRVDPAIPIEEVVGGMMELVKEGKVRHIALSEAG
PETLRRAAKAAPITALQSEYSIWERDVEDEILPVCREHGIGFVPYSPLGRGFLAGAVRSRDELPEHDWRRNDPRYSDENL
PANLAIVDAIGAVADKHGVSKAQVALAWLLARGEDIVPIPGTKRRATMEDSVGAADVTLTADDIEAIDSAAPKGGTSGPR
YGEQGMRMVRL

Sequences:

>Translated_331_residues
MKYRTLGHGLTVSAIGIGCMPMIKGGNILYGEAADLDEATRTIHRAIDLGVTFFDTAQIYGPFSNEELLGEAIRGKRDGL
VIATKFGFRFDGKQITGVDGSPENARKSCEGSLQRLGIDTIDLFYQHRVDPAIPIEEVVGGMMELVKEGKVRHIALSEAG
PETLRRAAKAAPITALQSEYSIWERDVEDEILPVCREHGIGFVPYSPLGRGFLAGAVRSRDELPEHDWRRNDPRYSDENL
PANLAIVDAIGAVADKHGVSKAQVALAWLLARGEDIVPIPGTKRRATMEDSVGAADVTLTADDIEAIDSAAPKGGTSGPR
YGEQGMRMVRL
>Mature_331_residues
MKYRTLGHGLTVSAIGIGCMPMIKGGNILYGEAADLDEATRTIHRAIDLGVTFFDTAQIYGPFSNEELLGEAIRGKRDGL
VIATKFGFRFDGKQITGVDGSPENARKSCEGSLQRLGIDTIDLFYQHRVDPAIPIEEVVGGMMELVKEGKVRHIALSEAG
PETLRRAAKAAPITALQSEYSIWERDVEDEILPVCREHGIGFVPYSPLGRGFLAGAVRSRDELPEHDWRRNDPRYSDENL
PANLAIVDAIGAVADKHGVSKAQVALAWLLARGEDIVPIPGTKRRATMEDSVGAADVTLTADDIEAIDSAAPKGGTSGPR
YGEQGMRMVRL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=329, Percent_Identity=28.2674772036474, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI27436969, Length=329, Percent_Identity=28.5714285714286, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI4504825, Length=327, Percent_Identity=28.4403669724771, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI27436962, Length=329, Percent_Identity=27.9635258358663, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI27436966, Length=329, Percent_Identity=27.6595744680851, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI27436971, Length=329, Percent_Identity=27.6595744680851, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI223718702, Length=185, Percent_Identity=32.972972972973, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI41327764, Length=185, Percent_Identity=32.4324324324324, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI41152114, Length=276, Percent_Identity=27.536231884058, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI87081735, Length=321, Percent_Identity=33.0218068535826, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1788070, Length=307, Percent_Identity=29.6416938110749, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1789375, Length=335, Percent_Identity=29.2537313432836, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787674, Length=306, Percent_Identity=29.7385620915033, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788081, Length=304, Percent_Identity=27.6315789473684, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1789199, Length=309, Percent_Identity=25.8899676375405, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI48994888, Length=279, Percent_Identity=26.1648745519713, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=333, Percent_Identity=27.9279279279279, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6325384, Length=314, Percent_Identity=28.0254777070064, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6323998, Length=323, Percent_Identity=26.625386996904, Blast_Score=102, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6319958, Length=277, Percent_Identity=26.3537906137184, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319951, Length=325, Percent_Identity=26.1538461538462, Blast_Score=99, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6322615, Length=257, Percent_Identity=26.0700389105058, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24646155, Length=227, Percent_Identity=32.15859030837, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24646159, Length=226, Percent_Identity=29.2035398230088, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35851; Mature: 35851

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYRTLGHGLTVSAIGIGCMPMIKGGNILYGEAADLDEATRTIHRAIDLGVTFFDTAQIY
CCCEECCCCCEEEEECCCCEEEECCCCEEECCCCCHHHHHHHHHHHHHHCCEEEEHHHHC
GPFSNEELLGEAIRGKRDGLVIATKFGFRFDGKQITGVDGSPENARKSCEGSLQRLGIDT
CCCCCHHHHHHHHCCCCCCEEEEEECCEEECCCEEECCCCCCHHHHHHHHHHHHHCCCHH
IDLFYQHRVDPAIPIEEVVGGMMELVKEGKVRHIALSEAGPETLRRAAKAAPITALQSEY
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHH
SIWERDVEDEILPVCREHGIGFVPYSPLGRGFLAGAVRSRDELPEHDWRRNDPRYSDENL
HHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
PANLAIVDAIGAVADKHGVSKAQVALAWLLARGEDIVPIPGTKRRATMEDSVGAADVTLT
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCHHCCCCCCEEEEE
ADDIEAIDSAAPKGGTSGPRYGEQGMRMVRL
HHHHHHHHHCCCCCCCCCCCCCHHCHHECCC
>Mature Secondary Structure
MKYRTLGHGLTVSAIGIGCMPMIKGGNILYGEAADLDEATRTIHRAIDLGVTFFDTAQIY
CCCEECCCCCEEEEECCCCEEEECCCCEEECCCCCHHHHHHHHHHHHHHCCEEEEHHHHC
GPFSNEELLGEAIRGKRDGLVIATKFGFRFDGKQITGVDGSPENARKSCEGSLQRLGIDT
CCCCCHHHHHHHHCCCCCCEEEEEECCEEECCCEEECCCCCCHHHHHHHHHHHHHCCCHH
IDLFYQHRVDPAIPIEEVVGGMMELVKEGKVRHIALSEAGPETLRRAAKAAPITALQSEY
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHH
SIWERDVEDEILPVCREHGIGFVPYSPLGRGFLAGAVRSRDELPEHDWRRNDPRYSDENL
HHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
PANLAIVDAIGAVADKHGVSKAQVALAWLLARGEDIVPIPGTKRRATMEDSVGAADVTLT
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCHHCCCCCCEEEEE
ADDIEAIDSAAPKGGTSGPRYGEQGMRMVRL
HHHHHHHHHCCCCCCCCCCCCCHHCHHECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377; 9298659 [H]