BacMap

Definition	Sphingopyxis alaskensis RB2256, complete genome.
Accession	NC_008048
Length	3,345,170

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The map label for this gene is bdhA [H]

Identifier: 103486428

GI number: 103486428

Start: 956765

End: 957550

Strand: Direct

Name: bdhA [H]

Synonym: Sala_0938

Alternate gene names: 103486428

Gene position: 956765-957550 (Clockwise)

Preceding gene: 103486427

Following gene: 103486429

Centisome position: 28.6

GC content: 63.99

Gene sequence:

>786_bases
ATGCACCTTAAAGGCAAGACTGCGCTCGTCACCGGATCGACTTCGGGCATCGGGCTCGGCATCGCCAAGGCCTTTGCCGC
CGACGGCGCGAACCTCATCATCAACGGCTTTGGCGATGCCGACGCGATCGAGGCCGAACGCAAGGAGCTGGAAGCGATCA
GCGGCGGCAAGGCTGCCTATGACGGCGCCGATCTGACCAAGCCTGACGAAATCATGGCGATGTTCACGCGCGCGGAGGCG
GATTTCGGCGGGGTCGACATCCTCGTCAACAATGCGGGGATGCAGTTCGTCTCGCCTGTCGAGGATTTTCCACCCGAAAA
GTGGGATATGATCATTGCGCTCAACCTGACCGCGGCCTTTCACACGATCCGTCATGCGGTGCCGGGGATGCGCAGGAAGA
AGTGGGGACGGATCATCGGCACCGCCTCGGCGCACTCGCTCGTCGCCTCGCCCTTCAAATCGGCCTATGTCACCGCGAAG
CACGGGCTGGCGGGCCTCACCAAAACGGTGGCGCTCGAAGTGGCGGACGCCGGAATCACCGTCAACTGCATCAGTCCGGG
TTATGTCTGGACACCGCTGGTCGAGAATCAGATTCCCGACACGATGAAGGCGCGCGGCATGACGCGCGAGCAGGTGATCA
ACGATGTGCTGCTCGCGGGGCAGCCGACGAAGCAGTTCGTCACGGTCGAGCAGGTCGCGGCGCTCGCCGCTTTCCTCACG
CGCGACGAGGCGGCGAACATCACCGGCGCGAACCTCAGCGTCGATGGCGGCTGGACCGCGGCCTGA

Upstream 100 bases:

>100_bases
CCGAGGGACGGTCGGACAGCTTCGCGGTGCAGGCCGACGGGCTGAAGCCCAAGGCCGACAAGGATATTCGCTGATTCTCC
CCCACCGAAAGGACAAGGAC

Downstream 100 bases:

>100_bases
TGCGGCGGCCTTGAGCATTCTCCTTTGCCACCCTAAGGTTAACCAAACAGGGCCGGGGAGAAACGGAGAATCATGGGTCG
CACCATCTGGGTTTTGGCGG

Product: 3-hydroxybutyrate dehydrogenase

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MHLKGKTALVTGSTSGIGLGIAKAFAADGANLIINGFGDADAIEAERKELEAISGGKAAYDGADLTKPDEIMAMFTRAEA
DFGGVDILVNNAGMQFVSPVEDFPPEKWDMIIALNLTAAFHTIRHAVPGMRRKKWGRIIGTASAHSLVASPFKSAYVTAK
HGLAGLTKTVALEVADAGITVNCISPGYVWTPLVENQIPDTMKARGMTREQVINDVLLAGQPTKQFVTVEQVAALAAFLT
RDEAANITGANLSVDGGWTAA

Sequences:

>Translated_261_residues
MHLKGKTALVTGSTSGIGLGIAKAFAADGANLIINGFGDADAIEAERKELEAISGGKAAYDGADLTKPDEIMAMFTRAEA
DFGGVDILVNNAGMQFVSPVEDFPPEKWDMIIALNLTAAFHTIRHAVPGMRRKKWGRIIGTASAHSLVASPFKSAYVTAK
HGLAGLTKTVALEVADAGITVNCISPGYVWTPLVENQIPDTMKARGMTREQVINDVLLAGQPTKQFVTVEQVAALAAFLT
RDEAANITGANLSVDGGWTAA
>Mature_261_residues
MHLKGKTALVTGSTSGIGLGIAKAFAADGANLIINGFGDADAIEAERKELEAISGGKAAYDGADLTKPDEIMAMFTRAEA
DFGGVDILVNNAGMQFVSPVEDFPPEKWDMIIALNLTAAFHTIRHAVPGMRRKKWGRIIGTASAHSLVASPFKSAYVTAK
HGLAGLTKTVALEVADAGITVNCISPGYVWTPLVENQIPDTMKARGMTREQVINDVLLAGQPTKQFVTVEQVAALAAFLT
RDEAANITGANLSVDGGWTAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI66933014, Length=259, Percent_Identity=34.3629343629344, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI32483357, Length=258, Percent_Identity=31.0077519379845, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI20149619, Length=253, Percent_Identity=30.4347826086957, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI19923817, Length=266, Percent_Identity=27.4436090225564, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4504505, Length=265, Percent_Identity=30.188679245283, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI7705925, Length=264, Percent_Identity=29.1666666666667, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI59889578, Length=239, Percent_Identity=30.5439330543933, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=27.363184079602, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI142976729, Length=245, Percent_Identity=30.2040816326531, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=28.0155642023346, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=31.1827956989247, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=32.2916666666667, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI4758504, Length=204, Percent_Identity=29.4117647058824, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4503301, Length=257, Percent_Identity=28.4046692607004, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI15277342, Length=269, Percent_Identity=26.7657992565056, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI126723750, Length=268, Percent_Identity=27.2388059701493, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI7657478, Length=191, Percent_Identity=28.2722513089005, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7706318, Length=194, Percent_Identity=29.8969072164948, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI40254992, Length=255, Percent_Identity=27.843137254902, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI40254986, Length=193, Percent_Identity=30.5699481865285, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI10190704, Length=255, Percent_Identity=24.7058823529412, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI109715829, Length=202, Percent_Identity=27.7227722772277, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI223718074, Length=191, Percent_Identity=25.6544502617801, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI224922801, Length=174, Percent_Identity=26.4367816091954, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI83715985, Length=189, Percent_Identity=27.5132275132275, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI226371731, Length=192, Percent_Identity=29.1666666666667, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=36.6795366795367, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787335, Length=265, Percent_Identity=35.0943396226415, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI87082160, Length=261, Percent_Identity=35.632183908046, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1790717, Length=266, Percent_Identity=30.8270676691729, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1788459, Length=257, Percent_Identity=31.1284046692607, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789208, Length=260, Percent_Identity=30.3846153846154, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI2367175, Length=255, Percent_Identity=31.7647058823529, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1789378, Length=263, Percent_Identity=28.8973384030418, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=28.6274509803922, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=28.4046692607004, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1786812, Length=262, Percent_Identity=27.8625954198473, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI2367365, Length=258, Percent_Identity=28.2945736434109, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786701, Length=193, Percent_Identity=25.9067357512953, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=259, Percent_Identity=27.7992277992278, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17560676, Length=266, Percent_Identity=30.4511278195489, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17555706, Length=257, Percent_Identity=26.8482490272374, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17538182, Length=213, Percent_Identity=31.4553990610329, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17536651, Length=262, Percent_Identity=27.4809160305344, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17536025, Length=262, Percent_Identity=28.2442748091603, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=271, Percent_Identity=28.4132841328413, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=273, Percent_Identity=31.1355311355311, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=30.2083333333333, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17508895, Length=196, Percent_Identity=28.0612244897959, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17561402, Length=264, Percent_Identity=27.6515151515151, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI193203115, Length=266, Percent_Identity=28.9473684210526, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI193203117, Length=268, Percent_Identity=28.7313432835821, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=276, Percent_Identity=28.6231884057971, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=271, Percent_Identity=28.7822878228782, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=280, Percent_Identity=27.1428571428571, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17561272, Length=262, Percent_Identity=28.2442748091603, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17568967, Length=244, Percent_Identity=27.8688524590164, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=272, Percent_Identity=30.1470588235294, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=259, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=273, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=278, Percent_Identity=28.7769784172662, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=268, Percent_Identity=27.9850746268657, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=279, Percent_Identity=26.5232974910394, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=274, Percent_Identity=29.5620437956204, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI86565303, Length=242, Percent_Identity=28.5123966942149, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=276, Percent_Identity=27.536231884058, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17555612, Length=242, Percent_Identity=28.9256198347107, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=26.2172284644195, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=257, Percent_Identity=27.2373540856031, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=277, Percent_Identity=28.5198555956679, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=278, Percent_Identity=29.4964028776978, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=201, Percent_Identity=28.3582089552239, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=273, Percent_Identity=29.3040293040293, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=255, Percent_Identity=25.4901960784314, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=199, Percent_Identity=28.1407035175879, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=246, Percent_Identity=29.6747967479675, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6324126, Length=258, Percent_Identity=23.2558139534884, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=194, Percent_Identity=27.319587628866, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24644339, Length=263, Percent_Identity=32.6996197718631, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI21355319, Length=262, Percent_Identity=30.5343511450382, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI23397609, Length=259, Percent_Identity=33.5907335907336, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21357041, Length=264, Percent_Identity=29.9242424242424, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28571526, Length=266, Percent_Identity=31.5789473684211, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI21358495, Length=252, Percent_Identity=26.5873015873016, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI18859837, Length=209, Percent_Identity=29.1866028708134, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24639444, Length=261, Percent_Identity=27.5862068965517, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24643142, Length=262, Percent_Identity=25.9541984732824, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI21355631, Length=255, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28574402, Length=194, Percent_Identity=29.8969072164948, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24584744, Length=194, Percent_Identity=29.8969072164948, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI28571387, Length=212, Percent_Identity=26.8867924528302, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21357673, Length=192, Percent_Identity=28.125, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281364892, Length=173, Percent_Identity=27.1676300578035, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24649181, Length=193, Percent_Identity=26.4248704663212, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17737361, Length=204, Percent_Identity=26.9607843137255, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640442, Length=192, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24641232, Length=227, Percent_Identity=26.431718061674, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI161076933, Length=207, Percent_Identity=28.9855072463768, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24584748, Length=207, Percent_Identity=28.9855072463768, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21356301, Length=197, Percent_Identity=25.3807106598985, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24644337, Length=262, Percent_Identity=28.6259541984733, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 27410; Mature: 27410

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLKGKTALVTGSTSGIGLGIAKAFAADGANLIINGFGDADAIEAERKELEAISGGKAAY
CCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCC
DGADLTKPDEIMAMFTRAEADFGGVDILVNNAGMQFVSPVEDFPPEKWDMIIALNLTAAF
CCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCEECCHHHCCCCCCCEEEEEEHHHHH
HTIRHAVPGMRRKKWGRIIGTASAHSLVASPFKSAYVTAKHGLAGLTKTVALEVADAGIT
HHHHHHCCCHHHHHHCCEEECCCHHHHHHCCHHHHEEEHHCCCHHHHHHEEEEEECCCEE
VNCISPGYVWTPLVENQIPDTMKARGMTREQVINDVLLAGQPTKQFVTVEQVAALAAFLT
EEEECCCEEECCHHHCCCCCHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
RDEAANITGANLSVDGGWTAA
HCCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure
MHLKGKTALVTGSTSGIGLGIAKAFAADGANLIINGFGDADAIEAERKELEAISGGKAAY
CCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCC
DGADLTKPDEIMAMFTRAEADFGGVDILVNNAGMQFVSPVEDFPPEKWDMIIALNLTAAF
CCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCEECCHHHCCCCCCCEEEEEEHHHHH
HTIRHAVPGMRRKKWGRIIGTASAHSLVASPFKSAYVTAKHGLAGLTKTVALEVADAGIT
HHHHHHCCCHHHHHHCCEEECCCHHHHHHCCHHHHEEEHHCCCHHHHHHEEEEEECCCEE
VNCISPGYVWTPLVENQIPDTMKARGMTREQVINDVLLAGQPTKQFVTVEQVAALAAFLT
EEEECCCEEECCHHHCCCCCHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
RDEAANITGANLSVDGGWTAA
HCCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9922248; 11481431 [H]