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The map label for this gene is yngJ [H]

Identifier: 103486345

GI number: 103486345

Start: 862877

End: 863869

Strand: Direct

Name: yngJ [H]

Synonym: Sala_0855

Alternate gene names: 103486345

Gene position: 862877-863869 (Clockwise)

Preceding gene: 103486344

Following gene: 103486346

Centisome position: 25.79

GC content: 68.78

Gene sequence:

>993_bases
GTGCATTTTCATCTGACCGAAGAGCAGGCCGCAATCCAGGAGGCGGTGCGGGGCACGCTGGCGGACCATTGGCCACTGGA
GCGCCTCCACGCCTTTGCCAACGGCGATGCCGACTTCGATCCGGACAGCTGGGATGCGCTGATGGCGCTTGGCCTGGGCG
GCGTCCTTGCGCCGGACAGCGGCATGGGTTTGCTCGAAGCCGCCCTGGTTTGCGAAGTCGCAGGCGAACGCGCTGCTCCT
GGGCCGCTTGTCGGGCAATTGCTGGCGGTGGCGGCCGTTGCGCATTGGGACGATTGCGACGCGGGCCTTCGGGATGCGCT
GACCAGCGGGACAGTGACGGTGGCGCTGATGCACGGCGGCAGCAGCTATGTTCCCTGTGCGCGGTCGGCCGGCCAGTTCC
TGGTCGTGGATCGCACGCGCGGCGTCCGTCTGGTCGAGGCCGCCGACGCGACGATCGAGCCGGTCCGCGCCAGCGACCGC
AGCCGTCCGGCATCGAAGGTAGAGATTGCCGCGGGCGCGGGGCGCTCGCTGTTCGCCGCCGATCATCCGATGACGGCGCG
ACTTGCCGATGCGGCGCTGGTTCTCGTCGCCGCCGACGCGCTGGGCGGCGCGCAAAGAGTCACCGACATGAGCGTCGCCT
ATGCCAAGGAACGCGAGCAGTTCGGACAGCCGATCGGCCGCTTTCAAGGCCTCAAGCACCAGCTTGCGCATATGGCGCTC
GATGTCGAACCGGCGCGTGCGCTGGTCTGGTACGCGGCCTATGCCTGGGATGCGGAACTGCCCGACGCTGCGCGCGCGGC
GGCGATGGCAAAGGCGCATCTGTGCGACATCTACGTCCGCGCAACGCGCGCCGCGGTCGCGGCGCATGGCGGCATCGGAT
ACACATGGGAATATGGCCTTCATTATTGGTTTCGGCGCGCCGCCTTCAATCGGGCCTGGCTCGGCAGCCCCGCCGAACAT
CGCGCGCGGGCGGCCGGTCTGGCAGGCTGGTAA

Upstream 100 bases:

>100_bases
AATTCGATCGCGGGGGGCACATCGAATATTCAACGCAATATCATTGGCGAGCGCGGGCTGGGGCTGCCCCGCGACCTTGC
GATAAGTGCGGAGCGCTGAC

Downstream 100 bases:

>100_bases
ATGAGCCGGACGGCCGACCATTCCGAACCGGCCCCCGGCGCGCGGCGCCTGCGCCCCGACGATCATTTCACGATCCTTGC
CGAAACCGACGCGTCGCCGA

Product: acyl-CoA dehydrogenase-like protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MHFHLTEEQAAIQEAVRGTLADHWPLERLHAFANGDADFDPDSWDALMALGLGGVLAPDSGMGLLEAALVCEVAGERAAP
GPLVGQLLAVAAVAHWDDCDAGLRDALTSGTVTVALMHGGSSYVPCARSAGQFLVVDRTRGVRLVEAADATIEPVRASDR
SRPASKVEIAAGAGRSLFAADHPMTARLADAALVLVAADALGGAQRVTDMSVAYAKEREQFGQPIGRFQGLKHQLAHMAL
DVEPARALVWYAAYAWDAELPDAARAAAMAKAHLCDIYVRATRAAVAAHGGIGYTWEYGLHYWFRRAAFNRAWLGSPAEH
RARAAGLAGW

Sequences:

>Translated_330_residues
MHFHLTEEQAAIQEAVRGTLADHWPLERLHAFANGDADFDPDSWDALMALGLGGVLAPDSGMGLLEAALVCEVAGERAAP
GPLVGQLLAVAAVAHWDDCDAGLRDALTSGTVTVALMHGGSSYVPCARSAGQFLVVDRTRGVRLVEAADATIEPVRASDR
SRPASKVEIAAGAGRSLFAADHPMTARLADAALVLVAADALGGAQRVTDMSVAYAKEREQFGQPIGRFQGLKHQLAHMAL
DVEPARALVWYAAYAWDAELPDAARAAAMAKAHLCDIYVRATRAAVAAHGGIGYTWEYGLHYWFRRAAFNRAWLGSPAEH
RARAAGLAGW
>Mature_330_residues
MHFHLTEEQAAIQEAVRGTLADHWPLERLHAFANGDADFDPDSWDALMALGLGGVLAPDSGMGLLEAALVCEVAGERAAP
GPLVGQLLAVAAVAHWDDCDAGLRDALTSGTVTVALMHGGSSYVPCARSAGQFLVVDRTRGVRLVEAADATIEPVRASDR
SRPASKVEIAAGAGRSLFAADHPMTARLADAALVLVAADALGGAQRVTDMSVAYAKEREQFGQPIGRFQGLKHQLAHMAL
DVEPARALVWYAAYAWDAELPDAARAAAMAKAHLCDIYVRATRAAVAAHGGIGYTWEYGLHYWFRRAAFNRAWLGSPAEH
RARAAGLAGW

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=120, Percent_Identity=39.1666666666667, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4557233, Length=137, Percent_Identity=34.3065693430657, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508101, Length=127, Percent_Identity=34.6456692913386, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17506239, Length=127, Percent_Identity=33.8582677165354, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356377, Length=137, Percent_Identity=31.3868613138686, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24646207, Length=181, Percent_Identity=29.8342541436464, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666513, Length=121, Percent_Identity=32.2314049586777, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24660351, Length=184, Percent_Identity=32.6086956521739, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 35007; Mature: 35007

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFHLTEEQAAIQEAVRGTLADHWPLERLHAFANGDADFDPDSWDALMALGLGGVLAPDS
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEECCCC
GMGLLEAALVCEVAGERAAPGPLVGQLLAVAAVAHWDDCDAGLRDALTSGTVTVALMHGG
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEEECC
SSYVPCARSAGQFLVVDRTRGVRLVEAADATIEPVRASDRSRPASKVEIAAGAGRSLFAA
CCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEC
DHPMTARLADAALVLVAADALGGAQRVTDMSVAYAKEREQFGQPIGRFQGLKHQLAHMAL
CCCCHHHHHHHHEEEEEHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
DVEPARALVWYAAYAWDAELPDAARAAAMAKAHLCDIYVRATRAAVAAHGGIGYTWEYGL
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHH
HYWFRRAAFNRAWLGSPAEHRARAAGLAGW
HHHHHHHHHCCCCCCCCHHHHHHHCCCCCC
>Mature Secondary Structure
MHFHLTEEQAAIQEAVRGTLADHWPLERLHAFANGDADFDPDSWDALMALGLGGVLAPDS
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEECCCC
GMGLLEAALVCEVAGERAAPGPLVGQLLAVAAVAHWDDCDAGLRDALTSGTVTVALMHGG
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEEECC
SSYVPCARSAGQFLVVDRTRGVRLVEAADATIEPVRASDRSRPASKVEIAAGAGRSLFAA
CCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEC
DHPMTARLADAALVLVAADALGGAQRVTDMSVAYAKEREQFGQPIGRFQGLKHQLAHMAL
CCCCHHHHHHHHEEEEEHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
DVEPARALVWYAAYAWDAELPDAARAAAMAKAHLCDIYVRATRAAVAAHGGIGYTWEYGL
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHH
HYWFRRAAFNRAWLGSPAEHRARAAGLAGW
HHHHHHHHHCCCCCCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]