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The map label for this gene is trpD

Identifier: 103486326

GI number: 103486326

Start: 842002

End: 843000

Strand: Reverse

Name: trpD

Synonym: Sala_0836

Alternate gene names: 103486326

Gene position: 843000-842002 (Counterclockwise)

Preceding gene: 103486327

Following gene: 103486325

Centisome position: 25.2

GC content: 70.37

Gene sequence:

>999_bases
ATGAGCCGGTTCGGGCCATTTCCCGACCCTTCGGCGCTGCTCGACCATGACGAGGCGGCGCACGCCTTCGCAACGATGCT
CGATGGCGGTGCGCGCGACGAACAGATCGCCGCGTTTCTGGTCGCGCTCGCCGACCGCGGCGAAACGATGGTCGAAATCG
CCGCCGCGGCACAGGCGATGCGCGATCGGCTGATCCCCATCGAGGCGCCGGCGGGCGCGATCGACGTGTGCGGCACCGGC
GGCGACGGACACCACACGCTCAACGTCTCGACGGCGGTGTCGATCGTCGTCGCGGCGTGCGACGTGCCGGTCGCAAAGCA
CGGCAATCGCGCGGCTTCGTCGAAATCGGGCGCCGCCGACACGCTGGAGGCGCTTGGCCTCGACATGGAGCGCGCCGATC
GTCAGGCGCAGGAACAGCTCGCCGACCTCGGCATCTGTTTCCTCTTCGCCGGGACGCGCCACCCTGCGATGAAGCGCATC
ATGCCGATCCGCAAGGCGATCGGGCGGCGGACGATCTTCAACCTGATGGGGCCGCTCGCCAATCCCGCGCGCGTCACCCG
CCAGCTTGTCGGCATCGCGCGCCCCGCCTATGTGCCCGTCTATGCCGAGGCGCTGCACCGGCTCGGCACCGATCATTCGC
GCGTCATTTCGGGCGACGAGGGGCTCGACGAACTCTCGCTCGCGGGCGGCAACGAGGTCGCGGTGGTGACCCCCGACGGC
GTGCGGATGCAGCGCAGCAGCGCCGCCGACGCCGGGCTGCCGACGCGCTCGCTCGCCGAAATCCGCGGCGGCGATGCGGC
GTTCAACGCCCGCGCGCTGCGCCGCCTGCTCGAAGGCGAAACCGGCGCGTACCGTGACGCGGTACTCTACAACGCCGCCG
CGGCGCTGATCGTCGCGGGCGCGGTCGACACGCTGACGGAGGGGGTCGAGGAAGCCGCCGAAGCGATCGACAAGGGCCTC
GCCAACGCGCTGCTCAACTGCTGGATCGCGTATAAATGA

Upstream 100 bases:

>100_bases
TCCAGTTCCACCCCGAAAGCATCGCGACCGAGCATGGCCATGCGATGCTCGCCAATTTCCTCCGTATCGCCGGGATTCCC
GTGCGCGAACGGCAAGCGGC

Downstream 100 bases:

>100_bases
GCGGGTTTTTGACATCGTCATTGCGAGGAGCCGAAGGCGACGCGGCAATCTCCAGCTTTCGTCCATCAAAATCGCTAGCT
GGAGGTTGCTTCGCTACGCT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MSRFGPFPDPSALLDHDEAAHAFATMLDGGARDEQIAAFLVALADRGETMVEIAAAAQAMRDRLIPIEAPAGAIDVCGTG
GDGHHTLNVSTAVSIVVAACDVPVAKHGNRAASSKSGAADTLEALGLDMERADRQAQEQLADLGICFLFAGTRHPAMKRI
MPIRKAIGRRTIFNLMGPLANPARVTRQLVGIARPAYVPVYAEALHRLGTDHSRVISGDEGLDELSLAGGNEVAVVTPDG
VRMQRSSAADAGLPTRSLAEIRGGDAAFNARALRRLLEGETGAYRDAVLYNAAAALIVAGAVDTLTEGVEEAAEAIDKGL
ANALLNCWIAYK

Sequences:

>Translated_332_residues
MSRFGPFPDPSALLDHDEAAHAFATMLDGGARDEQIAAFLVALADRGETMVEIAAAAQAMRDRLIPIEAPAGAIDVCGTG
GDGHHTLNVSTAVSIVVAACDVPVAKHGNRAASSKSGAADTLEALGLDMERADRQAQEQLADLGICFLFAGTRHPAMKRI
MPIRKAIGRRTIFNLMGPLANPARVTRQLVGIARPAYVPVYAEALHRLGTDHSRVISGDEGLDELSLAGGNEVAVVTPDG
VRMQRSSAADAGLPTRSLAEIRGGDAAFNARALRRLLEGETGAYRDAVLYNAAAALIVAGAVDTLTEGVEEAAEAIDKGL
ANALLNCWIAYK
>Mature_331_residues
SRFGPFPDPSALLDHDEAAHAFATMLDGGARDEQIAAFLVALADRGETMVEIAAAAQAMRDRLIPIEAPAGAIDVCGTGG
DGHHTLNVSTAVSIVVAACDVPVAKHGNRAASSKSGAADTLEALGLDMERADRQAQEQLADLGICFLFAGTRHPAMKRIM
PIRKAIGRRTIFNLMGPLANPARVTRQLVGIARPAYVPVYAEALHRLGTDHSRVISGDEGLDELSLAGGNEVAVVTPDGV
RMQRSSAADAGLPTRSLAEIRGGDAAFNARALRRLLEGETGAYRDAVLYNAAAALIVAGAVDTLTEGVEEAAEAIDKGLA
NALLNCWIAYK

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=268, Percent_Identity=38.4328358208955, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1787019, Length=308, Percent_Identity=22.0779220779221, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320561, Length=279, Percent_Identity=31.1827956989247, Blast_Score=122, Evalue=8e-29,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_SPHAL (Q1GUW8)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_615887.1
- ProteinModelPortal:   Q1GUW8
- SMR:   Q1GUW8
- GeneID:   4080044
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_0836
- NMPDR:   fig|317655.9.peg.782
- HOGENOM:   HBG559996
- OMA:   ATPSQMG
- ProtClustDB:   PRK00188
- BioCyc:   SALA317655:SALA_0836-MONOMER
- BRENDA:   2.4.2.18
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 34723; Mature: 34592

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRFGPFPDPSALLDHDEAAHAFATMLDGGARDEQIAAFLVALADRGETMVEIAAAAQAM
CCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RDRLIPIEAPAGAIDVCGTGGDGHHTLNVSTAVSIVVAACDVPVAKHGNRAASSKSGAAD
HHCCCCEECCCCCEEEECCCCCCCEEEEHHHHHHHHHHHHCCCHHHCCCCCCCCCCCHHH
TLEALGLDMERADRQAQEQLADLGICFLFAGTRHPAMKRIMPIRKAIGRRTIFNLMGPLA
HHHHHCCCHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
NPARVTRQLVGIARPAYVPVYAEALHRLGTDHSRVISGDEGLDELSLAGGNEVAVVTPDG
CHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEECCCCCCHHHHCCCCCEEEEECCCC
VRMQRSSAADAGLPTRSLAEIRGGDAAFNARALRRLLEGETGAYRDAVLYNAAAALIVAG
CEECCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AVDTLTEGVEEAAEAIDKGLANALLNCWIAYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRFGPFPDPSALLDHDEAAHAFATMLDGGARDEQIAAFLVALADRGETMVEIAAAAQAM
CCCCCCCCCHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
RDRLIPIEAPAGAIDVCGTGGDGHHTLNVSTAVSIVVAACDVPVAKHGNRAASSKSGAAD
HHCCCCEECCCCCEEEECCCCCCCEEEEHHHHHHHHHHHHCCCHHHCCCCCCCCCCCHHH
TLEALGLDMERADRQAQEQLADLGICFLFAGTRHPAMKRIMPIRKAIGRRTIFNLMGPLA
HHHHHCCCHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
NPARVTRQLVGIARPAYVPVYAEALHRLGTDHSRVISGDEGLDELSLAGGNEVAVVTPDG
CHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEECCCCCCHHHHCCCCCEEEEECCCC
VRMQRSSAADAGLPTRSLAEIRGGDAAFNARALRRLLEGETGAYRDAVLYNAAAALIVAG
CEECCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AVDTLTEGVEEAAEAIDKGLANALLNCWIAYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA