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The map label for this gene is dinB2 [H]

Identifier: 103486248

GI number: 103486248

Start: 764045

End: 765175

Strand: Reverse

Name: dinB2 [H]

Synonym: Sala_0756

Alternate gene names: 103486248

Gene position: 765175-764045 (Counterclockwise)

Preceding gene: 103486252

Following gene: 103486244

Centisome position: 22.87

GC content: 66.93

Gene sequence:

>1131_bases
GTGGACGACAGCGACGATCATGGCCTCGACGACGGCGCGGACCCGCCCCCGGTCCGCAAGATCATCCACGTCGACATGGA
CGCCTTTTACGCTTCGGTCGAACAGCGCGACGATCCCGCGCTCCGCGGCAAGCCGGTTGCGGTCGGCGGATCGTCGCGGC
GCGGCGTCGTTGCGGCCGCCTCCTATGAGGCGCGGCGGTTCGGCGTACGCTCGGCAATGCCCAGCATTACCGCGAAGCGC
CAGTGCCCCGGCCTCATCTTCGTGCCGCCGCGTTTCGAGGTTTACCGCGAGGTGTCGCATCAGATCCGCGCGATTTTCCG
CGATTATGCCGACGAGGTCGAGCCGCTGTCGCTCGACGAGGCCTATCTCGACGTCAGCGCCGACAAGGCGGGACTCGGCA
GCGCGACCGCGACCGCGCGGCTGATCCGCCGCCGCATCCGCGAAGAAACCGGGCTCACCGCCTCGGCCGGGGTATCCTAT
AACAAGTTCATCGCCAAGCTGGCGTCGGACCAGAACAAGCCGGACGGCCTCACCGTCATCCCGCCGGGCAAGGGCGCCGC
CTTTGTCCAGACGCTGTCGATCCGTCGTTTCCACGGCATCGGCCCTGTTACCGCGGCAAAAATGGAGGGGCTCGGCGTCT
TTTCGGGCGCCGACCTAGCCGCGAAAGATCCGTTGTGGCTCGCCGAGCATTTCGCCAACAGCGCCGAATGGCTCTATAAC
CTTGCCCGCGGGATCGACCATCGCCGCGTCAAGTCGAACCGGCCGCTCAAATCCTTGGGCGGCGAGCGCACCTTCTTCAA
CGACCTGATCACCGATACCGAAATCCGCGAGGCGCTGGCGCATGTCTGCACCGTGGTATGGGACCGCGCGGTGAAAAAGG
GCGCACGCGGGCGCACGGTGACGCTGAAGTTGCGCTACGCCGATTTCCGCACGATCACGCGCGCGAAGTCGGTGCCTTCG
CCGATCCGCGATGGCGCCAGCCTGCTCGCGGTGGGCGAGGCAATCCTGGCTCCCCTGCTGCCCAGCGAACAGGGCATCCG
CCTGCTCGGTGTCACGCTGAGCAAGTTCGAGGGCGAAGAGGAGGAGGGGGACGAAGCCCCCGCCCCCGCCGACCTGCTCA
GCCTTATTTAG

Upstream 100 bases:

>100_bases
CGTCCAAGGTCGGCGGCGATTGCCATTTTGATCGGTCGCCGTCAAGCGCGACGTCACGCGCGCCATTGAGAACATCATGG
CAACATGATAGCTTTGCGTT

Downstream 100 bases:

>100_bases
GGTCAGGACCCATTAATTACCCGTTCGAGGCGTCGAAATGGCGAAGATATCGGGCCTTGGCGGGTGCGGCGGGTAGCATC
GCTACCCGCAAGGCCGCGAA

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV 2 [H]

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MDDSDDHGLDDGADPPPVRKIIHVDMDAFYASVEQRDDPALRGKPVAVGGSSRRGVVAAASYEARRFGVRSAMPSITAKR
QCPGLIFVPPRFEVYREVSHQIRAIFRDYADEVEPLSLDEAYLDVSADKAGLGSATATARLIRRRIREETGLTASAGVSY
NKFIAKLASDQNKPDGLTVIPPGKGAAFVQTLSIRRFHGIGPVTAAKMEGLGVFSGADLAAKDPLWLAEHFANSAEWLYN
LARGIDHRRVKSNRPLKSLGGERTFFNDLITDTEIREALAHVCTVVWDRAVKKGARGRTVTLKLRYADFRTITRAKSVPS
PIRDGASLLAVGEAILAPLLPSEQGIRLLGVTLSKFEGEEEEGDEAPAPADLLSLI

Sequences:

>Translated_376_residues
MDDSDDHGLDDGADPPPVRKIIHVDMDAFYASVEQRDDPALRGKPVAVGGSSRRGVVAAASYEARRFGVRSAMPSITAKR
QCPGLIFVPPRFEVYREVSHQIRAIFRDYADEVEPLSLDEAYLDVSADKAGLGSATATARLIRRRIREETGLTASAGVSY
NKFIAKLASDQNKPDGLTVIPPGKGAAFVQTLSIRRFHGIGPVTAAKMEGLGVFSGADLAAKDPLWLAEHFANSAEWLYN
LARGIDHRRVKSNRPLKSLGGERTFFNDLITDTEIREALAHVCTVVWDRAVKKGARGRTVTLKLRYADFRTITRAKSVPS
PIRDGASLLAVGEAILAPLLPSEQGIRLLGVTLSKFEGEEEEGDEAPAPADLLSLI
>Mature_376_residues
MDDSDDHGLDDGADPPPVRKIIHVDMDAFYASVEQRDDPALRGKPVAVGGSSRRGVVAAASYEARRFGVRSAMPSITAKR
QCPGLIFVPPRFEVYREVSHQIRAIFRDYADEVEPLSLDEAYLDVSADKAGLGSATATARLIRRRIREETGLTASAGVSY
NKFIAKLASDQNKPDGLTVIPPGKGAAFVQTLSIRRFHGIGPVTAAKMEGLGVFSGADLAAKDPLWLAEHFANSAEWLYN
LARGIDHRRVKSNRPLKSLGGERTFFNDLITDTEIREALAHVCTVVWDRAVKKGARGRTVTLKLRYADFRTITRAKSVPS
PIRDGASLLAVGEAILAPLLPSEQGIRLLGVTLSKFEGEEEEGDEAPAPADLLSLI

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI154350220, Length=339, Percent_Identity=28.3185840707965, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI7705344, Length=106, Percent_Identity=53.7735849056604, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI84043967, Length=341, Percent_Identity=27.8592375366569, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI7706681, Length=342, Percent_Identity=27.7777777777778, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI5729982, Length=118, Percent_Identity=40.6779661016949, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1786425, Length=306, Percent_Identity=45.7516339869281, Blast_Score=247, Evalue=9e-67,
Organism=Escherichia coli, GI1787432, Length=217, Percent_Identity=29.4930875576037, Blast_Score=86, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI193205700, Length=410, Percent_Identity=31.9512195121951, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17537959, Length=188, Percent_Identity=34.5744680851064, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI193205702, Length=356, Percent_Identity=29.2134831460674, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI115534089, Length=123, Percent_Identity=41.4634146341463, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI21355641, Length=282, Percent_Identity=30.1418439716312, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24644984, Length=282, Percent_Identity=30.1418439716312, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI19923006, Length=337, Percent_Identity=24.6290801186944, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24668444, Length=235, Percent_Identity=24.6808510638298, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 40811; Mature: 40811

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDSDDHGLDDGADPPPVRKIIHVDMDAFYASVEQRDDPALRGKPVAVGGSSRRGVVAAA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCEEEEC
SYEARRFGVRSAMPSITAKRQCPGLIFVPPRFEVYREVSHQIRAIFRDYADEVEPLSLDE
CHHHHHHHHHHHCCCHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
AYLDVSADKAGLGSATATARLIRRRIREETGLTASAGVSYNKFIAKLASDQNKPDGLTVI
HHEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCEEEE
PPGKGAAFVQTLSIRRFHGIGPVTAAKMEGLGVFSGADLAAKDPLWLAEHFANSAEWLYN
CCCCCHHHHHHHHHHHHCCCCCCHHHHHCCCEEECCCCCCCCCCHHHHHHHCCHHHHHHH
LARGIDHRRVKSNRPLKSLGGERTFFNDLITDTEIREALAHVCTVVWDRAVKKGARGRTV
HHHCCCHHHHHCCCCHHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
TLKLRYADFRTITRAKSVPSPIRDGASLLAVGEAILAPLLPSEQGIRLLGVTLSKFEGEE
EEEEEECHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHCCCCC
EEGDEAPAPADLLSLI
CCCCCCCCCHHHHHHC
>Mature Secondary Structure
MDDSDDHGLDDGADPPPVRKIIHVDMDAFYASVEQRDDPALRGKPVAVGGSSRRGVVAAA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCEEEEC
SYEARRFGVRSAMPSITAKRQCPGLIFVPPRFEVYREVSHQIRAIFRDYADEVEPLSLDE
CHHHHHHHHHHHCCCHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
AYLDVSADKAGLGSATATARLIRRRIREETGLTASAGVSYNKFIAKLASDQNKPDGLTVI
HHEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCEEEE
PPGKGAAFVQTLSIRRFHGIGPVTAAKMEGLGVFSGADLAAKDPLWLAEHFANSAEWLYN
CCCCCHHHHHHHHHHHHCCCCCCHHHHHCCCEEECCCCCCCCCCHHHHHHHCCHHHHHHH
LARGIDHRRVKSNRPLKSLGGERTFFNDLITDTEIREALAHVCTVVWDRAVKKGARGRTV
HHHCCCHHHHHCCCCHHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
TLKLRYADFRTITRAKSVPSPIRDGASLLAVGEAILAPLLPSEQGIRLLGVTLSKFEGEE
EEEEEECHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHCCCCC
EEGDEAPAPADLLSLI
CCCCCCCCCHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]