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The map label for this gene is rlmH

Identifier: 103486069

GI number: 103486069

Start: 588247

End: 588675

Strand: Reverse

Name: rlmH

Synonym: Sala_0576

Alternate gene names: 103486069

Gene position: 588675-588247 (Counterclockwise)

Preceding gene: 103486070

Following gene: 103486068

Centisome position: 17.6

GC content: 66.43

Gene sequence:

>429_bases
ATGTTGCTGCACATCATCGCGCGCGGGCGCATCGGGCGCGGCCCGGAGGCCGAGCTGGTCGAGCGCTATATGAAGCGCGT
GACCTGGGCGCAGAAGATTTCGGAACTCCCCGACACCGGCGGGCGCGTTCCCGCCGCGGCAGCGGGCAGCCGCACCATAT
TGCTCGACGAGGGCGGCGAACAGATGTCCTCGCTCGAATTTGCAAATTTACTCGAAAACTGGCGCGATGGCGGAGTGCGC
GAGGCGCGCTTCTGCATTGGCGCCGCCGACGGTTTCACGCCCGACGAACGCAAGGGCGCCGACAAGGTCATCGCCTTTGG
CCGCGCGACCTGGCCGCATTTGATGGCGCGCGCGATGCTCGCCGAACAATTGTGGCGCGCCACCAGCATCATCGCAGGAC
ATCCCTATCACCGCGAGGGGCGCCAGTGA

Upstream 100 bases:

>100_bases
CAGCCCGCTCCCCCTCCCGGCCTCCCCAACGATAATAGCCTATGGGAGGCCGGGAGGGGGAGCGGGCTGGTGCCGCTTTC
ACCGAAGGTGAACAAAAACC

Downstream 100 bases:

>100_bases
GGCGCGGGCCCGCCGCGCTGGCGATCGTCGCCGCCTTCGCGGGCGGAACCTTCGCGCTGGCACAGGGCGACTTCTTCGAC
CCACAGGCCATCGCCACGCG

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MLLHIIARGRIGRGPEAELVERYMKRVTWAQKISELPDTGGRVPAAAAGSRTILLDEGGEQMSSLEFANLLENWRDGGVR
EARFCIGAADGFTPDERKGADKVIAFGRATWPHLMARAMLAEQLWRATSIIAGHPYHREGRQ

Sequences:

>Translated_142_residues
MLLHIIARGRIGRGPEAELVERYMKRVTWAQKISELPDTGGRVPAAAAGSRTILLDEGGEQMSSLEFANLLENWRDGGVR
EARFCIGAADGFTPDERKGADKVIAFGRATWPHLMARAMLAEQLWRATSIIAGHPYHREGRQ
>Mature_142_residues
MLLHIIARGRIGRGPEAELVERYMKRVTWAQKISELPDTGGRVPAAAAGSRTILLDEGGEQMSSLEFANLLENWRDGGVR
EARFCIGAADGFTPDERKGADKVIAFGRATWPHLMARAMLAEQLWRATSIIAGHPYHREGRQ

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

Organism=Escherichia coli, GI1786855, Length=100, Percent_Identity=36, Blast_Score=68, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH_SPHAL (Q1GVM5)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_615630.1
- ProteinModelPortal:   Q1GVM5
- SMR:   Q1GVM5
- GeneID:   4082007
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_0576
- HOGENOM:   HBG622807
- OMA:   ILSGHPY
- ProtClustDB:   CLSK835479
- BioCyc:   SALA317655:SALA_0576-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR003742
- PIRSF:   PIRSF004505

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 15738; Mature: 15738

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLHIIARGRIGRGPEAELVERYMKRVTWAQKISELPDTGGRVPAAAAGSRTILLDEGGE
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCH
QMSSLEFANLLENWRDGGVREARFCIGAADGFTPDERKGADKVIAFGRATWPHLMARAML
HHHHHHHHHHHHHHHCCCCCHHHHEEECCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHH
AEQLWRATSIIAGHPYHREGRQ
HHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLLHIIARGRIGRGPEAELVERYMKRVTWAQKISELPDTGGRVPAAAAGSRTILLDEGGE
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCH
QMSSLEFANLLENWRDGGVREARFCIGAADGFTPDERKGADKVIAFGRATWPHLMARAML
HHHHHHHHHHHHHHHCCCCCHHHHEEECCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHH
AEQLWRATSIIAGHPYHREGRQ
HHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA