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The map label for this gene is fabG [H]

Identifier: 103486048

GI number: 103486048

Start: 569650

End: 570342

Strand: Reverse

Name: fabG [H]

Synonym: Sala_0555

Alternate gene names: 103486048

Gene position: 570342-569650 (Counterclockwise)

Preceding gene: 103486049

Following gene: 103486047

Centisome position: 17.05

GC content: 66.81

Gene sequence:

>693_bases
ATGCCAACCCATATCCTGATCACCGGCGCGAGCCGCGGCATCGGCGCGGCGATCGCCGAAGCGCTGACCTCCACCGCAAC
GAAGATCGTCGCCCTGTCGAGCGCCGACGGCGACCTCGGCGACCCGGCAACCCCCGACCGGCTGTGGCACACGAGCCTCG
ACCAACTGGATGGCCGTATCGACATACTCGTCAACAACGCCGGGGTGTTCGAGGCGAACCCCCTCGACGCGACCGATGCC
GAATGGCTCGCGAACTGGAACCGCACGATGCAGATAAATCTGACCGCGAGCGCGCAGCTGTGCCGCCGCGCGGTGTTGCA
CTGGCAGGCGCGCCAATCGGGCGGCCGCATCGTCAATATCGCGAGCCGCGCCGCCTATCGCGGCGACAGCCCCGTGCACT
GGCATTATGCGGCGTCGAAAGCGGGCATGGTCGCGATGACCAAGACGATCGCGCGCGCTTATGCCAGGGATGGTATCCTC
GCCTTTGCCATCTGCCCCGGCTTCACGATGACGGGCATGGCCGACGAATATCTGGAAAGCCGCGGCGGCGAGAAATTGCT
CGCCGACATTCCGCTGGGCCGTGTCGCGATGCCGGACGAGGTCGGCGAAATGGCGCGCTGGTGCGCGATGCAGGCGCCCG
CGTCGATGACCGGCGCGATACTCGACATCAACGGCGCCAGCTATGTCCGCTGA

Upstream 100 bases:

>100_bases
CGCCCTCTCACGCACCGGCGAGATCCCGGCCTTCGCCGGGATGACGAGTTTGCGGATGCGCCCGCTTGGCAAGCCCAGCC
CCGCTGCCTAAAGCCGCGTC

Downstream 100 bases:

>100_bases
ATGAGCTGGATCGTCTCCTTTCCCTGTACGCGCGCCGAGGCCGAGGCGCTGTCGGGCGAGATTCCCGCGCTTGATGCGCT
GGACGCGCCCCCGGTGGTGG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MPTHILITGASRGIGAAIAEALTSTATKIVALSSADGDLGDPATPDRLWHTSLDQLDGRIDILVNNAGVFEANPLDATDA
EWLANWNRTMQINLTASAQLCRRAVLHWQARQSGGRIVNIASRAAYRGDSPVHWHYAASKAGMVAMTKTIARAYARDGIL
AFAICPGFTMTGMADEYLESRGGEKLLADIPLGRVAMPDEVGEMARWCAMQAPASMTGAILDINGASYVR

Sequences:

>Translated_230_residues
MPTHILITGASRGIGAAIAEALTSTATKIVALSSADGDLGDPATPDRLWHTSLDQLDGRIDILVNNAGVFEANPLDATDA
EWLANWNRTMQINLTASAQLCRRAVLHWQARQSGGRIVNIASRAAYRGDSPVHWHYAASKAGMVAMTKTIARAYARDGIL
AFAICPGFTMTGMADEYLESRGGEKLLADIPLGRVAMPDEVGEMARWCAMQAPASMTGAILDINGASYVR
>Mature_229_residues
PTHILITGASRGIGAAIAEALTSTATKIVALSSADGDLGDPATPDRLWHTSLDQLDGRIDILVNNAGVFEANPLDATDAE
WLANWNRTMQINLTASAQLCRRAVLHWQARQSGGRIVNIASRAAYRGDSPVHWHYAASKAGMVAMTKTIARAYARDGILA
FAICPGFTMTGMADEYLESRGGEKLLADIPLGRVAMPDEVGEMARWCAMQAPASMTGAILDINGASYVR

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=236, Percent_Identity=30.0847457627119, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI7705925, Length=234, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI31542939, Length=237, Percent_Identity=29.535864978903, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=26.1044176706827, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=25.2918287937743, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=31.2757201646091, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=31.2, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=29.2, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=28.0487804878049, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786812, Length=244, Percent_Identity=27.4590163934426, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=25.9109311740891, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=28.515625, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=256, Percent_Identity=28.515625, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=25.8823529411765, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=260, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=256, Percent_Identity=26.953125, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=239, Percent_Identity=26.7782426778243, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=257, Percent_Identity=26.4591439688716, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=243, Percent_Identity=25.9259259259259, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=239, Percent_Identity=25.9414225941423, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=242, Percent_Identity=26.4462809917355, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=234, Percent_Identity=29.4871794871795, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=239, Percent_Identity=23.0125523012552, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=29.6875, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=28.6290322580645, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=29.8804780876494, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24540; Mature: 24409

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTHILITGASRGIGAAIAEALTSTATKIVALSSADGDLGDPATPDRLWHTSLDQLDGRI
CCCEEEEECCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCHHHHCCHHHCCCEE
DILVNNAGVFEANPLDATDAEWLANWNRTMQINLTASAQLCRRAVLHWQARQSGGRIVNI
EEEEECCCEEECCCCCCCCHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCEEEEE
ASRAAYRGDSPVHWHYAASKAGMVAMTKTIARAYARDGILAFAICPGFTMTGMADEYLES
EHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEECCCCEECCCHHHHHHH
RGGEKLLADIPLGRVAMPDEVGEMARWCAMQAPASMTGAILDINGASYVR
CCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
PTHILITGASRGIGAAIAEALTSTATKIVALSSADGDLGDPATPDRLWHTSLDQLDGRI
CCEEEEECCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCHHHHCCHHHCCCEE
DILVNNAGVFEANPLDATDAEWLANWNRTMQINLTASAQLCRRAVLHWQARQSGGRIVNI
EEEEECCCEEECCCCCCCCHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHCCCCEEEEE
ASRAAYRGDSPVHWHYAASKAGMVAMTKTIARAYARDGILAFAICPGFTMTGMADEYLES
EHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEECCCCEECCCHHHHHHH
RGGEKLLADIPLGRVAMPDEVGEMARWCAMQAPASMTGAILDINGASYVR
CCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]