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The map label for this gene is yiaY [H]

Identifier: 103485803

GI number: 103485803

Start: 311952

End: 313118

Strand: Reverse

Name: yiaY [H]

Synonym: Sala_0308

Alternate gene names: 103485803

Gene position: 313118-311952 (Counterclockwise)

Preceding gene: 103485804

Following gene: 103485796

Centisome position: 9.36

GC content: 69.07

Gene sequence:

>1167_bases
TTGAGCATCGCAAGCATCGCCCTTCCCCGCATCCTCCGCATCGGCGGCGGCGCGTCGAAACAACTCGGCGAGGTGCTGGA
GACATTGGGTCTGTCGCGCCCGCTGATCGTTACCGACCCCTGGCTGCTGAACAGCGGGCGCGTCGACGAACTGGCGGGCG
GGCTGGCAAGCGCCGGGATCGCCGCGCGGGTGTTCGCCGATACCGTGCCCGACCCCACCATCGCCTCGATCAACGTCGGC
GTAGCCTTCCTTCAGGAAGGCGACCATGATTGCGTCGTCGGCTTCGGCGGCGGCAGCCCGCTCGACAGCGCCAAGGCGAT
CGCGCTGCTTGGCCACCACGGCGGCGCGATGGCCGATTACAAGGCGCCGCATGTGCAGGACACGCCCGGCTTGCCGGTGA
TCGCCATCCCGACGACCGCGGGCACCGGGTCGGAGGCGACGCGCTTCACGATCATCACCGACGATGCGACCGACGAAAAG
ATGCTCTGCCCCGGCCTTGCCTATCTGCCCGTCGCCGCGCTCGTCGATTATGAACTGACCTTTACCAAGCCCCGGCGGCT
GACCGCCGATACCGGCATCGATTCGCTGACGCACGCGATCGAGGCCTATGTCTCGCGCCGCGCCAATCCGTTCAGCGACG
GCATGGCAATGCTCGCGATGCGTGCGATCGCGCCCAATCTGCGCCGCGTATGCGCGGACCCGATGGACGCCGCAGCGCGC
GAGGCGATGATGCTCGGCGCAACGCAGGCGGGGATTGCCTTTTCGAACAGCTCGGTCGCGCTCGTCCACGGGATGAGCCG
ACCGATCGGCGCGCATTTCCATGTCCCGCACGGCTTGTCGAACGCGATGCTGCTGCCCGCCGTTACCGCCTGGTCGGCGC
CCGCCGCGCTTCCCCGCTACGCCGACTGCGCGCGCGCGATGGGCGTCGCCGACGATGCCGAGGGCGATCAGGCGGCGGTG
GCGCGGCTGATCGACGAACTCGCGGCGCTCAACCGCGAGCTGGAGGTGCCGGGCCCCGCGGCATGGGGTATCGACGCCGC
GCGCTGGGACGCGCTGATCCCGACGATGTGCGCGCAGGCGGCGGCATCGGGTTCGCCCGCCAACAATCCGCGCATCCCCG
ATGCCGACGAGATGGCGATGCTTTATGCAAAGATTTGGGCCGGCTAG

Upstream 100 bases:

>100_bases
CGCGCTCGACCTCTTCGCGCGGACGATCGGCGCGCGTACAGAATAAGGATTTCCGCCCGGCGCCCTGCAACGTAAGACCC
TCCTGTCAGGAGATCGTCCG

Downstream 100 bases:

>100_bases
GTCCCTTCGTTCATCGTCGGGCAATCCGCGCCCTGCTTAAGCGCGCTCGCCCCGCTTCCCGCTCTCCTGCGTCTCAATGT
CGGGGGCGGGGCATCGCTTC

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSIASIALPRILRIGGGASKQLGEVLETLGLSRPLIVTDPWLLNSGRVDELAGGLASAGIAARVFADTVPDPTIASINVG
VAFLQEGDHDCVVGFGGGSPLDSAKAIALLGHHGGAMADYKAPHVQDTPGLPVIAIPTTAGTGSEATRFTIITDDATDEK
MLCPGLAYLPVAALVDYELTFTKPRRLTADTGIDSLTHAIEAYVSRRANPFSDGMAMLAMRAIAPNLRRVCADPMDAAAR
EAMMLGATQAGIAFSNSSVALVHGMSRPIGAHFHVPHGLSNAMLLPAVTAWSAPAALPRYADCARAMGVADDAEGDQAAV
ARLIDELAALNRELEVPGPAAWGIDAARWDALIPTMCAQAAASGSPANNPRIPDADEMAMLYAKIWAG

Sequences:

>Translated_388_residues
MSIASIALPRILRIGGGASKQLGEVLETLGLSRPLIVTDPWLLNSGRVDELAGGLASAGIAARVFADTVPDPTIASINVG
VAFLQEGDHDCVVGFGGGSPLDSAKAIALLGHHGGAMADYKAPHVQDTPGLPVIAIPTTAGTGSEATRFTIITDDATDEK
MLCPGLAYLPVAALVDYELTFTKPRRLTADTGIDSLTHAIEAYVSRRANPFSDGMAMLAMRAIAPNLRRVCADPMDAAAR
EAMMLGATQAGIAFSNSSVALVHGMSRPIGAHFHVPHGLSNAMLLPAVTAWSAPAALPRYADCARAMGVADDAEGDQAAV
ARLIDELAALNRELEVPGPAAWGIDAARWDALIPTMCAQAAASGSPANNPRIPDADEMAMLYAKIWAG
>Mature_387_residues
SIASIALPRILRIGGGASKQLGEVLETLGLSRPLIVTDPWLLNSGRVDELAGGLASAGIAARVFADTVPDPTIASINVGV
AFLQEGDHDCVVGFGGGSPLDSAKAIALLGHHGGAMADYKAPHVQDTPGLPVIAIPTTAGTGSEATRFTIITDDATDEKM
LCPGLAYLPVAALVDYELTFTKPRRLTADTGIDSLTHAIEAYVSRRANPFSDGMAMLAMRAIAPNLRRVCADPMDAAARE
AMMLGATQAGIAFSNSSVALVHGMSRPIGAHFHVPHGLSNAMLLPAVTAWSAPAALPRYADCARAMGVADDAEGDQAAVA
RLIDELAALNRELEVPGPAAWGIDAARWDALIPTMCAQAAASGSPANNPRIPDADEMAMLYAKIWAG

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=381, Percent_Identity=31.496062992126, Blast_Score=126, Evalue=4e-29,
Organism=Escherichia coli, GI48994951, Length=341, Percent_Identity=39.8826979472141, Blast_Score=231, Evalue=8e-62,
Organism=Escherichia coli, GI1789163, Length=376, Percent_Identity=34.5744680851064, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI87082107, Length=384, Percent_Identity=35.6770833333333, Blast_Score=201, Evalue=8e-53,
Organism=Escherichia coli, GI1787493, Length=395, Percent_Identity=33.1645569620253, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI1789386, Length=297, Percent_Identity=24.9158249158249, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17537053, Length=414, Percent_Identity=28.5024154589372, Blast_Score=144, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6321181, Length=342, Percent_Identity=36.5497076023392, Blast_Score=200, Evalue=4e-52,
Organism=Drosophila melanogaster, GI24657991, Length=335, Percent_Identity=30.4477611940298, Blast_Score=115, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 40141; Mature: 40010

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIASIALPRILRIGGGASKQLGEVLETLGLSRPLIVTDPWLLNSGRVDELAGGLASAGI
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEECCEEECCCCHHHHHHHHHHCCH
AARVFADTVPDPTIASINVGVAFLQEGDHDCVVGFGGGSPLDSAKAIALLGHHGGAMADY
HHHHHHCCCCCCCEEEEECCEEEEECCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCCC
KAPHVQDTPGLPVIAIPTTAGTGSEATRFTIITDDATDEKMLCPGLAYLPVAALVDYELT
CCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCEEEE
FTKPRRLTADTGIDSLTHAIEAYVSRRANPFSDGMAMLAMRAIAPNLRRVCADPMDAAAR
ECCCCCEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
EAMMLGATQAGIAFSNSSVALVHGMSRPIGAHFHVPHGLSNAMLLPAVTAWSAPAALPRY
HHHHHCCHHHCEEECCCCEEEEECCCCCCCCEEECCCCCCCCCHHHHHHHCCCCCCCCHH
ADCARAMGVADDAEGDQAAVARLIDELAALNRELEVPGPAAWGIDAARWDALIPTMCAQA
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AASGSPANNPRIPDADEMAMLYAKIWAG
HCCCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIASIALPRILRIGGGASKQLGEVLETLGLSRPLIVTDPWLLNSGRVDELAGGLASAGI
CCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEECCEEECCCCHHHHHHHHHHCCH
AARVFADTVPDPTIASINVGVAFLQEGDHDCVVGFGGGSPLDSAKAIALLGHHGGAMADY
HHHHHHCCCCCCCEEEEECCEEEEECCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCCC
KAPHVQDTPGLPVIAIPTTAGTGSEATRFTIITDDATDEKMLCPGLAYLPVAALVDYELT
CCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCEEEE
FTKPRRLTADTGIDSLTHAIEAYVSRRANPFSDGMAMLAMRAIAPNLRRVCADPMDAAAR
ECCCCCEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
EAMMLGATQAGIAFSNSSVALVHGMSRPIGAHFHVPHGLSNAMLLPAVTAWSAPAALPRY
HHHHHCCHHHCEEECCCCEEEEECCCCCCCCEEECCCCCCCCCHHHHHHHCCCCCCCCHH
ADCARAMGVADDAEGDQAAVARLIDELAALNRELEVPGPAAWGIDAARWDALIPTMCAQA
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AASGSPANNPRIPDADEMAMLYAKIWAG
HCCCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]