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The map label for this gene is plsC [C]

Identifier: 103485689

GI number: 103485689

Start: 204922

End: 206478

Strand: Direct

Name: plsC [C]

Synonym: Sala_0193

Alternate gene names: 103485689

Gene position: 204922-206478 (Clockwise)

Preceding gene: 103485688

Following gene: 103485690

Centisome position: 6.13

GC content: 62.81

Gene sequence:

>1557_bases
GTGCCAAGACCGCAGCCGCATCTGGATGAAGTGCTCGCGTCCGAGCCCGGATCGCATATCGCCGCGCTTTTCGATTTCGA
CGGAACGATCATCGCCGGCTATTCGGCGACCGCGATGCTGCGCGAAAAGTTCCAGCGCCGCGAAATGTCGGTCGAGGAGA
TTGCCGAAACCGCACAGGTGATCGCGCAGCATAGCCTGGGCCAGATCGGCTTTTCCGGCCTGATGACTGCCGCCGCCAGA
TTCATGAAGGGGGTCGACGAGCAAAGCTTCATCGACTTCGGCGAGGAACTCTACCGCAAGCATATCGCGCGCAAAATCTA
TCCCGAAACGCGCGCGATCATCGAGGCGCATCAGGCCAAGGGTCATCGCGTCGCAATCATCTCGTCGGCGACGATCTACC
AGATCGAACCGACCGCGCGCGATCTCGGCATCACGGACATCAAATGCTCGGCCTATGAGATCGAGGACGGGGTTTTCACC
GGCGAAATCATCCGCCCGCTCTGTTTCGGCGAGGGCAAGGTGCTCGCCGCCGAGGACCTTGCCGCCGACTATGGCCTCGA
TCTCGATCAGAGCTATTTCTATTCGGACAGCGACGACGATATCGAACTTTTGGAGCGCGTCGGCAAACCGCGTCCGCTCA
ACCCGAACATGAAATTAAAGGCGATCGCCGACGAGCGCGGCTGGCCGGTGCAGCGCTTTGCAAGCCGCGGCACACCGTCG
TGGATCGACTATGCCCGCACCCTCTATGCCACCGGCTCGCTCGTCGGCGCCTTCGCCGCGGGCCTGCCGATCTGGGCGCT
CACCCGCTCGCAGCGCGAGGCGGTCAATTTCTCGATGGGGCTGTTCGGCGACTTCGCCACTGCGATCACCGGTGTCGAGC
TGGAGGTCGAGGGCGAGCGCCACCTCTGGTCGTCGCGCCCCTGCGTCTTCGTCTTCAACCATCAGAGCAAGGCCGATGTA
ATGATCCTCGCCAAGCTCATCCGCCGCGACATGGGCGGGGTGGGCAAGAAGGAGATCAGGGACATCCCCATCCTCGGCAA
GCTGATGGAATGGGGCGGCACCGTCTTCGTCGACCGCGCCGATGGAAAGAGCGCGATCAAGGCGATGGAACCGCTGATCG
ATGCGATCCAGAAGGAAGGCAAGTCGATCTGCATCGCGCCCGAAGGGACGCGCAGCCTGACCCCGAAGCTCGAACCCTTC
AAAAAGGGCGCTTTCCACCTCGCGATGCAGGCCGGTGTCCCGATCGTCCCGATCGTGATTCATAACGCCACGGACGTCGC
GCCGAAGAACGAGTTTGTGATGCGCCCCGCGACGGTGCGCGTCACCGTGCTGCCGCCCGTCGATACGTCGGGGTGGAGCG
TCCGCACGATCAACAACCATGTCCGTGACGTGCGCAACATGTTCCTGCGCACGCTGGGGCAGCCGCAGGAAAGCGTCGCG
GAATCGGTGGCGAGGGAAGCTGCGGTCGAGGCAAAGGGGGAAAAGACTCCGAAGAAGGCGGCCACCAAAAGGGCCGCGCC
GAAGAAGAAGGCAACCGGAAAGAGCGCCAAGGCATGA

Upstream 100 bases:

>100_bases
CCCAAAGGAACGCCGGATTTCCCGGCCATTGATAAACGCCATCTTACCTGCCATCGTGCAGCCCTGAAGCGGCAGGATGA
CCGCCTGTGGGGAGATGTGC

Downstream 100 bases:

>100_bases
CTGCACATCCCTTTCCCGTTCGCATCGAGCGAAGTCGAGATGCCTATCGGCCGGGCGCGTGCCGTCGGCGTGTCTCGACT
TCGCTCGACACGAGCGGGGA

Product: HAD family hydrolase

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 517

Protein sequence:

>518_residues
MPRPQPHLDEVLASEPGSHIAALFDFDGTIIAGYSATAMLREKFQRREMSVEEIAETAQVIAQHSLGQIGFSGLMTAAAR
FMKGVDEQSFIDFGEELYRKHIARKIYPETRAIIEAHQAKGHRVAIISSATIYQIEPTARDLGITDIKCSAYEIEDGVFT
GEIIRPLCFGEGKVLAAEDLAADYGLDLDQSYFYSDSDDDIELLERVGKPRPLNPNMKLKAIADERGWPVQRFASRGTPS
WIDYARTLYATGSLVGAFAAGLPIWALTRSQREAVNFSMGLFGDFATAITGVELEVEGERHLWSSRPCVFVFNHQSKADV
MILAKLIRRDMGGVGKKEIRDIPILGKLMEWGGTVFVDRADGKSAIKAMEPLIDAIQKEGKSICIAPEGTRSLTPKLEPF
KKGAFHLAMQAGVPIVPIVIHNATDVAPKNEFVMRPATVRVTVLPPVDTSGWSVRTINNHVRDVRNMFLRTLGQPQESVA
ESVAREAAVEAKGEKTPKKAATKRAAPKKKATGKSAKA

Sequences:

>Translated_518_residues
MPRPQPHLDEVLASEPGSHIAALFDFDGTIIAGYSATAMLREKFQRREMSVEEIAETAQVIAQHSLGQIGFSGLMTAAAR
FMKGVDEQSFIDFGEELYRKHIARKIYPETRAIIEAHQAKGHRVAIISSATIYQIEPTARDLGITDIKCSAYEIEDGVFT
GEIIRPLCFGEGKVLAAEDLAADYGLDLDQSYFYSDSDDDIELLERVGKPRPLNPNMKLKAIADERGWPVQRFASRGTPS
WIDYARTLYATGSLVGAFAAGLPIWALTRSQREAVNFSMGLFGDFATAITGVELEVEGERHLWSSRPCVFVFNHQSKADV
MILAKLIRRDMGGVGKKEIRDIPILGKLMEWGGTVFVDRADGKSAIKAMEPLIDAIQKEGKSICIAPEGTRSLTPKLEPF
KKGAFHLAMQAGVPIVPIVIHNATDVAPKNEFVMRPATVRVTVLPPVDTSGWSVRTINNHVRDVRNMFLRTLGQPQESVA
ESVAREAAVEAKGEKTPKKAATKRAAPKKKATGKSAKA
>Mature_517_residues
PRPQPHLDEVLASEPGSHIAALFDFDGTIIAGYSATAMLREKFQRREMSVEEIAETAQVIAQHSLGQIGFSGLMTAAARF
MKGVDEQSFIDFGEELYRKHIARKIYPETRAIIEAHQAKGHRVAIISSATIYQIEPTARDLGITDIKCSAYEIEDGVFTG
EIIRPLCFGEGKVLAAEDLAADYGLDLDQSYFYSDSDDDIELLERVGKPRPLNPNMKLKAIADERGWPVQRFASRGTPSW
IDYARTLYATGSLVGAFAAGLPIWALTRSQREAVNFSMGLFGDFATAITGVELEVEGERHLWSSRPCVFVFNHQSKADVM
ILAKLIRRDMGGVGKKEIRDIPILGKLMEWGGTVFVDRADGKSAIKAMEPLIDAIQKEGKSICIAPEGTRSLTPKLEPFK
KGAFHLAMQAGVPIVPIVIHNATDVAPKNEFVMRPATVRVTVLPPVDTSGWSVRTINNHVRDVRNMFLRTLGQPQESVAE
SVAREAAVEAKGEKTPKKAATKRAAPKKKATGKSAKA

Specific function: Converts Lysophosphatidic Acid (Lpa) Into Phosphatidic Acid By Incorporating An Acyl Moiety At The 2 Position. This Enzyme Can Utilize Either Acyl-CoA Or Acyl-Acyl Carrier Protein As The Fatty Acyl Donor. [C]

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI6041665, Length=208, Percent_Identity=34.6153846153846, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI5453718, Length=163, Percent_Identity=35.5828220858896, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI15100175, Length=163, Percent_Identity=35.5828220858896, Blast_Score=101, Evalue=2e-21,
Organism=Escherichia coli, GI1789395, Length=211, Percent_Identity=30.8056872037915, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17568319, Length=223, Percent_Identity=28.6995515695067, Blast_Score=92, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17564032, Length=215, Percent_Identity=24.1860465116279, Blast_Score=82, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6320151, Length=240, Percent_Identity=30.8333333333333, Blast_Score=118, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24641614, Length=210, Percent_Identity=28.5714285714286, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24641612, Length=210, Percent_Identity=28.5714285714286, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281364648, Length=166, Percent_Identity=31.9277108433735, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24582856, Length=166, Percent_Identity=31.9277108433735, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24582854, Length=166, Percent_Identity=31.9277108433735, Blast_Score=93, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR006385 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 2.3.1.51; 3.1.3.3

Molecular weight: Translated: 56846; Mature: 56715

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPQPHLDEVLASEPGSHIAALFDFDGTIIAGYSATAMLREKFQRREMSVEEIAETAQV
CCCCCCHHHHHHHCCCCCCEEEEEECCCCEEECCHHHHHHHHHHHHHCCCHHHHHHHHHH
IAQHSLGQIGFSGLMTAAARFMKGVDEQSFIDFGEELYRKHIARKIYPETRAIIEAHQAK
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
GHRVAIISSATIYQIEPTARDLGITDIKCSAYEIEDGVFTGEIIRPLCFGEGKVLAAEDL
CCEEEEEECCEEEEECCCHHHCCCCEEEEEEEEECCCCEEHHHHHHHHCCCCCEEEHHHH
AADYGLDLDQSYFYSDSDDDIELLERVGKPRPLNPNMKLKAIADERGWPVQRFASRGTPS
HHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHCCCCCH
WIDYARTLYATGSLVGAFAAGLPIWALTRSQREAVNFSMGLFGDFATAITGVELEVEGER
HHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHCCHHHHHHHHHHHHCCCEEEECCCH
HLWSSRPCVFVFNHQSKADVMILAKLIRRDMGGVGKKEIRDIPILGKLMEWGGTVFVDRA
HHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHCCCEEEEECC
DGKSAIKAMEPLIDAIQKEGKSICIAPEGTRSLTPKLEPFKKGAFHLAMQAGVPIVPIVI
CCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHCCCEEEHHHCCCCEEEEEE
HNATDVAPKNEFVMRPATVRVTVLPPVDTSGWSVRTINNHVRDVRNMFLRTLGQPQESVA
ECCCCCCCCCCEEECCCEEEEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHH
ESVAREAAVEAKGEKTPKKAATKRAAPKKKATGKSAKA
HHHHHHHHHHCCCCCCCHHHHHHHCCCCHHCCCCCCCC
>Mature Secondary Structure 
PRPQPHLDEVLASEPGSHIAALFDFDGTIIAGYSATAMLREKFQRREMSVEEIAETAQV
CCCCCHHHHHHHCCCCCCEEEEEECCCCEEECCHHHHHHHHHHHHHCCCHHHHHHHHHH
IAQHSLGQIGFSGLMTAAARFMKGVDEQSFIDFGEELYRKHIARKIYPETRAIIEAHQAK
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
GHRVAIISSATIYQIEPTARDLGITDIKCSAYEIEDGVFTGEIIRPLCFGEGKVLAAEDL
CCEEEEEECCEEEEECCCHHHCCCCEEEEEEEEECCCCEEHHHHHHHHCCCCCEEEHHHH
AADYGLDLDQSYFYSDSDDDIELLERVGKPRPLNPNMKLKAIADERGWPVQRFASRGTPS
HHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHCCCCCH
WIDYARTLYATGSLVGAFAAGLPIWALTRSQREAVNFSMGLFGDFATAITGVELEVEGER
HHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHCCHHHHHHHHHHHHCCCEEEECCCH
HLWSSRPCVFVFNHQSKADVMILAKLIRRDMGGVGKKEIRDIPILGKLMEWGGTVFVDRA
HHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHCCCEEEEECC
DGKSAIKAMEPLIDAIQKEGKSICIAPEGTRSLTPKLEPFKKGAFHLAMQAGVPIVPIVI
CCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHCCCEEEHHHCCCCEEEEEE
HNATDVAPKNEFVMRPATVRVTVLPPVDTSGWSVRTINNHVRDVRNMFLRTLGQPQESVA
ECCCCCCCCCCEEECCCEEEEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHH
ESVAREAAVEAKGEKTPKKAATKRAAPKKKATGKSAKA
HHHHHHHHHHCCCCCCCHHHHHHHCCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]