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The map label for this gene is sucC [H]

Identifier: 103485672

GI number: 103485672

Start: 179980

End: 181260

Strand: Direct

Name: sucC [H]

Synonym: Sala_0176

Alternate gene names: 103485672

Gene position: 179980-181260 (Clockwise)

Preceding gene: 103485671

Following gene: 103485673

Centisome position: 5.38

GC content: 63.62

Gene sequence:

>1281_bases
TTGCCGCGCAACTTGGCTTATGCGGCGCCAAACTTCTCCCTCTTCCTAGAGTCGAAAGGCCCGGCAGACCTCATGAACAT
TCACGAATATCAGGCGAAAGAACTGCTCGCGAAATTTGGCGTCGCCGTGCCCAGGGGCATCGCCGCGATGAGCGTCGAGG
AAGCTGTCGCGGCGGCGAAGCAGCTACCGGGGCCGCTCTATGTCGTGAAGTCACAAATCCACGCCGGTGGCCGCGGCAAG
GGCAAGTTCAAGGAACTAGGCCCCGACGCGAAGGGCGGCGTCCGTCTCGCCAGGAGCATCGAGGAAGTCGGGAGCCACGC
GCGTGAAATGCTCGGCAACACGCTGGTGACGATCCAGACCGGCGAAGCGGGCAAGCAGGTCAACCGGCTCTACATCACCG
ACGGCGCCGACATTAAGAAAGAATATTATCTCGCGCTCCTCGTCGATCGCGCGTCGAGCCGCATCGCGGTGGTCGCTTCG
ACCGAAGGCGGGATGGACATCGAGACCGTCGCGCACAACACGCCGGACAAGATTCACACGATCACCATCGACCCCGCGAC
CGGGCTGATGCCGCACCACGGCCGCAGCGTCGCCGCCGCGCTCGAACTGACCGGCGACCTCGCCAAGCAGGCGGCGAAGG
TGCTCGCCGGGCTTTACGACGCCTTCCTCGCGACCGACGCCGAACAGATCGAGATCAACCCGCTTGCCGTCTGCGAAGGC
GCGAACGGCGACGAACTGCTCGTGCTCGACGCGAAGCTCGGCTTCGACGGCAACGCGATGTTCCGCCACCCCGATATCGC
CGAACTGCGCGATCTGACCGAAGAAGATCCGGCCGAAGTCGAGGCGTCCGAATATGACCTTGCCTATATCAAGCTCGACG
GCAACATCGGCTGCATGGTCAATGGTGCGGGTCTCGCGATGGCGACGATGGACATCATCAAGCTGAACGGCGCCTTCCCG
GCGAACTTCCTCGACGTCGGCGGCGGCGCGAGCAAGGAAAAGGTCACCGCGGCGTTCAAGATCATCCTGAAAGACCCCGC
GGTCGAGGGCATCCTCGTCAACATCTTCGGCGGCATCATGAAGTGCGACATCATCGCCGACGGCATCGTCGCCGCGGCGA
AGGAAGTGAACCTGTCGGTCCCGCTCGTCGTTCGCCTCGAAGGCACGAACGTGCAGCAGGGCAAGGACATTCTCGCGAAC
TCGGGCCTGCCGATCGTGGCGGCCAACGATCTGGGCGATGCGGCGAAAAAGATCGTCGCCGAGGTTGCGAGGGCGGCGTG
A

Upstream 100 bases:

>100_bases
AGCTCGGCGGCGGTGTGCGCGCTGCGGTGACGCCATAGGGTCCTGGCCCTAGGCCGAGCTTTCGCCCGTCCAAGATAAAC
TGGGCGCGGCAGGGGTAGCC

Downstream 100 bases:

>100_bases
TACGAAATTGCCTCTCCCCTTGGGGGAGAGGCAGCGAGACTTGGCAGCTCGCTGCCTAGGGTCAGGACCCATTAATTACC
CGTTCGAGGTTTGAAGCGGA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MPRNLAYAAPNFSLFLESKGPADLMNIHEYQAKELLAKFGVAVPRGIAAMSVEEAVAAAKQLPGPLYVVKSQIHAGGRGK
GKFKELGPDAKGGVRLARSIEEVGSHAREMLGNTLVTIQTGEAGKQVNRLYITDGADIKKEYYLALLVDRASSRIAVVAS
TEGGMDIETVAHNTPDKIHTITIDPATGLMPHHGRSVAAALELTGDLAKQAAKVLAGLYDAFLATDAEQIEINPLAVCEG
ANGDELLVLDAKLGFDGNAMFRHPDIAELRDLTEEDPAEVEASEYDLAYIKLDGNIGCMVNGAGLAMATMDIIKLNGAFP
ANFLDVGGGASKEKVTAAFKIILKDPAVEGILVNIFGGIMKCDIIADGIVAAAKEVNLSVPLVVRLEGTNVQQGKDILAN
SGLPIVAANDLGDAAKKIVAEVARAA

Sequences:

>Translated_426_residues
MPRNLAYAAPNFSLFLESKGPADLMNIHEYQAKELLAKFGVAVPRGIAAMSVEEAVAAAKQLPGPLYVVKSQIHAGGRGK
GKFKELGPDAKGGVRLARSIEEVGSHAREMLGNTLVTIQTGEAGKQVNRLYITDGADIKKEYYLALLVDRASSRIAVVAS
TEGGMDIETVAHNTPDKIHTITIDPATGLMPHHGRSVAAALELTGDLAKQAAKVLAGLYDAFLATDAEQIEINPLAVCEG
ANGDELLVLDAKLGFDGNAMFRHPDIAELRDLTEEDPAEVEASEYDLAYIKLDGNIGCMVNGAGLAMATMDIIKLNGAFP
ANFLDVGGGASKEKVTAAFKIILKDPAVEGILVNIFGGIMKCDIIADGIVAAAKEVNLSVPLVVRLEGTNVQQGKDILAN
SGLPIVAANDLGDAAKKIVAEVARAA
>Mature_425_residues
PRNLAYAAPNFSLFLESKGPADLMNIHEYQAKELLAKFGVAVPRGIAAMSVEEAVAAAKQLPGPLYVVKSQIHAGGRGKG
KFKELGPDAKGGVRLARSIEEVGSHAREMLGNTLVTIQTGEAGKQVNRLYITDGADIKKEYYLALLVDRASSRIAVVAST
EGGMDIETVAHNTPDKIHTITIDPATGLMPHHGRSVAAALELTGDLAKQAAKVLAGLYDAFLATDAEQIEINPLAVCEGA
NGDELLVLDAKLGFDGNAMFRHPDIAELRDLTEEDPAEVEASEYDLAYIKLDGNIGCMVNGAGLAMATMDIIKLNGAFPA
NFLDVGGGASKEKVTAAFKIILKDPAVEGILVNIFGGIMKCDIIADGIVAAAKEVNLSVPLVVRLEGTNVQQGKDILANS
GLPIVAANDLGDAAKKIVAEVARAA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI157779135, Length=390, Percent_Identity=49.2307692307692, Blast_Score=352, Evalue=3e-97,
Organism=Homo sapiens, GI11321583, Length=395, Percent_Identity=45.5696202531646, Blast_Score=338, Evalue=4e-93,
Organism=Homo sapiens, GI294862256, Length=370, Percent_Identity=47.8378378378378, Blast_Score=325, Evalue=7e-89,
Organism=Escherichia coli, GI1786948, Length=398, Percent_Identity=53.0150753768844, Blast_Score=398, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17539378, Length=417, Percent_Identity=45.8033573141487, Blast_Score=344, Evalue=5e-95,
Organism=Caenorhabditis elegans, GI17567829, Length=399, Percent_Identity=44.3609022556391, Blast_Score=330, Evalue=1e-90,
Organism=Saccharomyces cerevisiae, GI6321683, Length=395, Percent_Identity=47.5949367088608, Blast_Score=378, Evalue=1e-106,
Organism=Drosophila melanogaster, GI21356231, Length=404, Percent_Identity=50.990099009901, Blast_Score=375, Evalue=1e-104,
Organism=Drosophila melanogaster, GI281361397, Length=391, Percent_Identity=47.5703324808184, Blast_Score=339, Evalue=3e-93,
Organism=Drosophila melanogaster, GI281361395, Length=391, Percent_Identity=47.5703324808184, Blast_Score=339, Evalue=3e-93,
Organism=Drosophila melanogaster, GI161078106, Length=391, Percent_Identity=47.3145780051151, Blast_Score=336, Evalue=2e-92,
Organism=Drosophila melanogaster, GI24645208, Length=391, Percent_Identity=47.3145780051151, Blast_Score=336, Evalue=2e-92,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 44698; Mature: 44567

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRNLAYAAPNFSLFLESKGPADLMNIHEYQAKELLAKFGVAVPRGIAAMSVEEAVAAAK
CCCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
QLPGPLYVVKSQIHAGGRGKGKFKELGPDAKGGVRLARSIEEVGSHAREMLGNTLVTIQT
HCCCCEEEEEHHHCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEE
GEAGKQVNRLYITDGADIKKEYYLALLVDRASSRIAVVASTEGGMDIETVAHNTPDKIHT
CCCCCCCCEEEEECCCCCCHHEEEEEEEECCCCEEEEEEECCCCCEEEECCCCCCCCEEE
ITIDPATGLMPHHGRSVAAALELTGDLAKQAAKVLAGLYDAFLATDAEQIEINPLAVCEG
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECEEEEEEC
ANGDELLVLDAKLGFDGNAMFRHPDIAELRDLTEEDPAEVEASEYDLAYIKLDGNIGCMV
CCCCEEEEEEEEECCCCCEEECCCCHHHHHCCCCCCCCCCCCCCCEEEEEEECCCEEEEE
NGAGLAMATMDIIKLNGAFPANFLDVGGGASKEKVTAAFKIILKDPAVEGILVNIFGGIM
ECCCCEEEEEEEEEECCCCCCCEEECCCCCCHHHHEEEEEEEEECCCCCEEHEEHHCCHH
KCDIIADGIVAAAKEVNLSVPLVVRLEGTNVQQGKDILANSGLPIVAANDLGDAAKKIVA
EEHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHCCCCCEEEECCCCHHHHHHHH
EVARAA
HHHHCC
>Mature Secondary Structure 
PRNLAYAAPNFSLFLESKGPADLMNIHEYQAKELLAKFGVAVPRGIAAMSVEEAVAAAK
CCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
QLPGPLYVVKSQIHAGGRGKGKFKELGPDAKGGVRLARSIEEVGSHAREMLGNTLVTIQT
HCCCCEEEEEHHHCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEE
GEAGKQVNRLYITDGADIKKEYYLALLVDRASSRIAVVASTEGGMDIETVAHNTPDKIHT
CCCCCCCCEEEEECCCCCCHHEEEEEEEECCCCEEEEEEECCCCCEEEECCCCCCCCEEE
ITIDPATGLMPHHGRSVAAALELTGDLAKQAAKVLAGLYDAFLATDAEQIEINPLAVCEG
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECEEEEEEC
ANGDELLVLDAKLGFDGNAMFRHPDIAELRDLTEEDPAEVEASEYDLAYIKLDGNIGCMV
CCCCEEEEEEEEECCCCCEEECCCCHHHHHCCCCCCCCCCCCCCCEEEEEEECCCEEEEE
NGAGLAMATMDIIKLNGAFPANFLDVGGGASKEKVTAAFKIILKDPAVEGILVNIFGGIM
ECCCCEEEEEEEEEECCCCCCCEEECCCCCCHHHHEEEEEEEEECCCCCEEHEEHHCCHH
KCDIIADGIVAAAKEVNLSVPLVVRLEGTNVQQGKDILANSGLPIVAANDLGDAAKKIVA
EEHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHCCCCCEEEECCCCHHHHHHHH
EVARAA
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA