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The map label for this gene is aatA [H]

Identifier: 103485668

GI number: 103485668

Start: 175960

End: 177171

Strand: Direct

Name: aatA [H]

Synonym: Sala_0172

Alternate gene names: 103485668

Gene position: 175960-177171 (Clockwise)

Preceding gene: 103485667

Following gene: 103485669

Centisome position: 5.26

GC content: 66.01

Gene sequence:

>1212_bases
ATGTCGCTGAAGCCGCATATATCCGCTGCCCTCGGGCGCATCCAGCCCTCCGCCACGCTCGCGATGACCGCGCGGGTCGC
CAGGCTGAAGGCCGAGGGCGTCGATGTCATCGGCCTGTCGGCGGGCGAGCCCGACTTCGACACCCCCGATTTCGTCAAGG
AAGCGGCGATCGAGGCAATCCGCGCGGGACAGACCAAATATACGCTCGTCGACGGCACGGTCGCGCTCAAGGAAGCGATC
CGCGGCAAGTTTCGCCGCGACAACGACCTCGATTATGGCCTCGACCAGATCACGGTCAATGTCGGCGGCAAGCACACCCT
GTTCAACGCGCTCGTCGCGACGGTCGACAAGGGCGACGAGGTCATCATCCCGGCACCCTATTGGGTGAGCTATCCCGACA
TCGTCGCCTTCGCGGGTGGCACGCCCGTCTTCGTGGCTGCGTCGGCGGCGCAGCATTACAAGATCACGCCCGGACAACTC
GACGCGGCGATCACGCCCAGGACGCGCTGGGTGATTTTCAACTCGCCATCAAATCCCTCGGGCGCCGCCTATTCGCCGGC
GGAACTCGACGCGATCGGCGAGGTGATCCGTCGCCATCCGCACGTCATGGTGATGACCGACGACATGTATGAGCATGTCT
GGTACGCCGACTTCGCCTTTTCGACGATCGCGCAGCGCTGCCCCGACCTGGTCGACCGCATCCTCACCGTGAACGGCTGT
TCCAAGGCCTATGCGATGACCGGCTGGCGCATCGGATATGCGGGCGGCCCGGCGTGGCTGATCAAGGCGATGGGCAAGCT
CCAGTCGCAATCGACCTCGAACCCCTGTTCGATCGCGCAGGCCGCCGCCGCCGCCGCGCTCGGCGGGCCGCAGCAGTTCC
TCGACGATCGCAACGCGGCGTTCCGCAAGCGCCGCGACATGGTCGTCGCGATGCTCAACGATGCCCCCGGCCTCAATTGC
CCGGTCCCCGATGGCGCCTTTTACGTCTATCCCGACGCATCGGGCTGCATGGGCAAGAAAACGCCGTCGGGACAGGTGAT
CGACAGCGACGAGGCGTTGATCGACTATTTCCTCGATTCGGCGCGCGTCGCCGCGGTGCATGGCGCCGCCTTCGGCCTGT
CGCCGGCGTTCCGCGTCTCCTATGCGACCTCCGAAGCGGTGCTGAAGGAAGCGTGCGTGCGCATCCAGCAGGCGTGCGCG
GCGCTGAGCTAG

Upstream 100 bases:

>100_bases
AGGAAATTATCGCGCCGCCGCCTTGCGATTTGCGGGCGGAGGCTTTAGGCGCGGCCGCGCGCAATTTCCTGTCAGTCCGC
TCGCGAAGGAAGACTTCTCC

Downstream 100 bases:

>100_bases
AGAGCGCTTTAGAGCGGTTTCGCAGGCTCTGGATTGCCGCGTCGCTTCGTTCCTCGCAATGACGATTGAAGCGATCATCG
TCCACTCCAAAGCTTGACGA

Product: aminotransferase, class I and II

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MSLKPHISAALGRIQPSATLAMTARVARLKAEGVDVIGLSAGEPDFDTPDFVKEAAIEAIRAGQTKYTLVDGTVALKEAI
RGKFRRDNDLDYGLDQITVNVGGKHTLFNALVATVDKGDEVIIPAPYWVSYPDIVAFAGGTPVFVAASAAQHYKITPGQL
DAAITPRTRWVIFNSPSNPSGAAYSPAELDAIGEVIRRHPHVMVMTDDMYEHVWYADFAFSTIAQRCPDLVDRILTVNGC
SKAYAMTGWRIGYAGGPAWLIKAMGKLQSQSTSNPCSIAQAAAAAALGGPQQFLDDRNAAFRKRRDMVVAMLNDAPGLNC
PVPDGAFYVYPDASGCMGKKTPSGQVIDSDEALIDYFLDSARVAAVHGAAFGLSPAFRVSYATSEAVLKEACVRIQQACA
ALS

Sequences:

>Translated_403_residues
MSLKPHISAALGRIQPSATLAMTARVARLKAEGVDVIGLSAGEPDFDTPDFVKEAAIEAIRAGQTKYTLVDGTVALKEAI
RGKFRRDNDLDYGLDQITVNVGGKHTLFNALVATVDKGDEVIIPAPYWVSYPDIVAFAGGTPVFVAASAAQHYKITPGQL
DAAITPRTRWVIFNSPSNPSGAAYSPAELDAIGEVIRRHPHVMVMTDDMYEHVWYADFAFSTIAQRCPDLVDRILTVNGC
SKAYAMTGWRIGYAGGPAWLIKAMGKLQSQSTSNPCSIAQAAAAAALGGPQQFLDDRNAAFRKRRDMVVAMLNDAPGLNC
PVPDGAFYVYPDASGCMGKKTPSGQVIDSDEALIDYFLDSARVAAVHGAAFGLSPAFRVSYATSEAVLKEACVRIQQACA
ALS
>Mature_402_residues
SLKPHISAALGRIQPSATLAMTARVARLKAEGVDVIGLSAGEPDFDTPDFVKEAAIEAIRAGQTKYTLVDGTVALKEAIR
GKFRRDNDLDYGLDQITVNVGGKHTLFNALVATVDKGDEVIIPAPYWVSYPDIVAFAGGTPVFVAASAAQHYKITPGQLD
AAITPRTRWVIFNSPSNPSGAAYSPAELDAIGEVIRRHPHVMVMTDDMYEHVWYADFAFSTIAQRCPDLVDRILTVNGCS
KAYAMTGWRIGYAGGPAWLIKAMGKLQSQSTSNPCSIAQAAAAAALGGPQQFLDDRNAAFRKRRDMVVAMLNDAPGLNCP
VPDGAFYVYPDASGCMGKKTPSGQVIDSDEALIDYFLDSARVAAVHGAAFGLSPAFRVSYATSEAVLKEACVRIQQACAA
LS

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=385, Percent_Identity=27.012987012987, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI169881279, Length=385, Percent_Identity=27.012987012987, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI56713254, Length=322, Percent_Identity=28.8819875776398, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI56713256, Length=322, Percent_Identity=28.8819875776398, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI169881281, Length=381, Percent_Identity=23.3595800524934, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI4507369, Length=383, Percent_Identity=22.976501305483, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1786816, Length=378, Percent_Identity=29.8941798941799, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788627, Length=357, Percent_Identity=29.6918767507003, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1788722, Length=401, Percent_Identity=28.1795511221945, Blast_Score=112, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI71994472, Length=259, Percent_Identity=28.5714285714286, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71994476, Length=259, Percent_Identity=28.5714285714286, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17567369, Length=323, Percent_Identity=27.8637770897833, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17567663, Length=383, Percent_Identity=23.2375979112272, Blast_Score=93, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322401, Length=322, Percent_Identity=25.4658385093168, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28573069, Length=323, Percent_Identity=26.3157894736842, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24646114, Length=323, Percent_Identity=26.3157894736842, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28573067, Length=323, Percent_Identity=26.3157894736842, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28573065, Length=323, Percent_Identity=26.3157894736842, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI18859735, Length=395, Percent_Identity=22.2784810126582, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42994; Mature: 42863

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00105 AA_TRANSFER_CLASS_1 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKPHISAALGRIQPSATLAMTARVARLKAEGVDVIGLSAGEPDFDTPDFVKEAAIEAI
CCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHH
RAGQTKYTLVDGTVALKEAIRGKFRRDNDLDYGLDQITVNVGGKHTLFNALVATVDKGDE
HCCCCEEEEECCHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCE
VIIPAPYWVSYPDIVAFAGGTPVFVAASAAQHYKITPGQLDAAITPRTRWVIFNSPSNPS
EEECCCCCCCCCCCEEECCCCCEEEEECCCCCEECCCCCCCEEECCCEEEEEEECCCCCC
GAAYSPAELDAIGEVIRRHPHVMVMTDDMYEHVWYADFAFSTIAQRCPDLVDRILTVNGC
CCCCCCHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
SKAYAMTGWRIGYAGGPAWLIKAMGKLQSQSTSNPCSIAQAAAAAALGGPQQFLDDRNAA
CHHHEECCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHCCHHHH
FRKRRDMVVAMLNDAPGLNCPVPDGAFYVYPDASGCMGKKTPSGQVIDSDEALIDYFLDS
HHHHHCEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEECCCHHHHHHHHCC
ARVAAVHGAAFGLSPAFRVSYATSEAVLKEACVRIQQACAALS
CCEEEEECHHHCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLKPHISAALGRIQPSATLAMTARVARLKAEGVDVIGLSAGEPDFDTPDFVKEAAIEAI
CCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHH
RAGQTKYTLVDGTVALKEAIRGKFRRDNDLDYGLDQITVNVGGKHTLFNALVATVDKGDE
HCCCCEEEEECCHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCE
VIIPAPYWVSYPDIVAFAGGTPVFVAASAAQHYKITPGQLDAAITPRTRWVIFNSPSNPS
EEECCCCCCCCCCCEEECCCCCEEEEECCCCCEECCCCCCCEEECCCEEEEEEECCCCCC
GAAYSPAELDAIGEVIRRHPHVMVMTDDMYEHVWYADFAFSTIAQRCPDLVDRILTVNGC
CCCCCCHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
SKAYAMTGWRIGYAGGPAWLIKAMGKLQSQSTSNPCSIAQAAAAAALGGPQQFLDDRNAA
CHHHEECCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHCCHHHH
FRKRRDMVVAMLNDAPGLNCPVPDGAFYVYPDASGCMGKKTPSGQVIDSDEALIDYFLDS
HHHHHCEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEECCCHHHHHHHHCC
ARVAAVHGAAFGLSPAFRVSYATSEAVLKEACVRIQQACAALS
CCEEEEECHHHCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]