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The map label for this gene is divL [H]

Identifier: 103485658

GI number: 103485658

Start: 161199

End: 163562

Strand: Reverse

Name: divL [H]

Synonym: Sala_0162

Alternate gene names: 103485658

Gene position: 163562-161199 (Counterclockwise)

Preceding gene: 103485659

Following gene: 103485657

Centisome position: 4.89

GC content: 71.07

Gene sequence:

>2364_bases
ATGAGCGGCACGCTTTCCCCGACCCTGCTGTTCGCCCTTGGCCTGTTCGCGGCGCTATGGTTGCTCGCCGGCCTGTGGGC
GACCTTGCGCGGGATTGCGATGCAGCGGCGCGCAGCTTTCGCGGGCGGCCAGGCCGAACGGCTTGCGAGCCTCGTCGAAG
CGTCGCCGCAACTCCCCGTGATCGTCCGCGCCGACTGGCGGATCGAAGCCAGCGACCGGCTCGGTCGCTGGCTGGGGCTC
GACCGCGGACCGCGCAATTTCGACGAACTGCGCGGGATCGGCAGCGGGCTCGACGCCGCGAGTCACGACCTGCTGCGCCA
GGCGATTCTCGGCGCGCAGCGCGGCGCCAAGCCATTCCAGCTGAGCCTCAAGCCCGAAGGGAGCCATCGCACCATCATCG
TCCAGGGCGCCGCGGCGCCGCAGGCGGTCGGCGGGGCGGGCAGCGTCCTCCTGTGGCTCAGCGACGCGACCGAGGGACAA
CAGGCGCTCGCCCATGCCCGCGCCGAGCGCGACGAGGCGCTGGCCGCCTTCGAGGCCTTGTCGGGGCTCATCGAGGCGGC
GCCCTTCCCCATGTGGTTCCGGGACACCGACTTGCAGCTCGCGCTCGTCAACGCCGCCTATGTCCGCGCGGTCGAGGCCA
GGAGCGCCACCGCGGTGATCGACGGCGGCATCGAGCTTTGCGAAACCGTCGCGGGAGTGAGCGCCGCCGACGCCGCCGAC
GCCGCGCGCGCGGCGGGATCGGCGCAGCAGCGCACCATCCCGGTGACGATCGAGGGCGAGCGGCGGATCATGCGCGTCGT
CGATGTGCCGCTCGCGCCCGAGGGCGGCCGCATGATCGGCATCGCGGGCTATGCGATCGACATTCAGGAACTGGAAAGCG
AACGCGGCGCGCATCGCCGCTTCGTCGATACGCAACGCGAGCTGCTCGACCGGCTGTCGGCCGCGGTCGCGCAATTCGGC
CCCGACCAGGGCCTCGCCTTTGCCAACCTGCCTTTTCGCCGCCTGTTCGGGCTGGATGCGGACGATGTGGGGGAGGCGCG
GCCGTTCGCCCGGCTGCTCGATGCATGGCGCGAGCGCGGCCGGACGCCGGAGGTACGCGACTATCCCGAATGGCGGCAAG
CGCATGTCGACTGGTTTGCGCGAGCCGAAGCAAGCGAAGAGGATTGGCGCCTGCGCGACGGCACGCACCTGCACGTCGTC
GCGCAGCCGACCCCCGACGGTGGGCTGTTGCTGATCGCCGAGGACAAGACCGAGCAGGTCCAGCTCGCCGGGGCGCGCGA
CACGCTGCTGCGCGTGCGCACCGCAACCTTCGACAATCTGTTCGAGGCGGTCGCGGTCTTTGCTCCCGACGGCCGCCTGC
ACCTCTGGAACCAGCGCTTCCGCCGCCTGTGGGGCGTCGACGAGCCGACGCTGGCCGCGCACCCGCGCGTCGACGTGCTG
ATGGGCGGGCTCGCCGACCGGCTCGCCAAGCCGAACCAGATCAGCGTCGTCCAGGAAGTGATCCGCGCCGCGACGCTCGA
ACGCCAGCAGCGCGTCGGCGAGATCCGCTTTGCCGACGGGCGCCATTTCGACTTCGCGTCGATCCCGCTGCCCGACGGTA
ATGCGCTGCTCATCATGCTCGACATCACCGCCAGCCGGAAGATGGAGGGCGCGCTGCGCGAGCGCAACGAAGCGCTCGAA
GCGGCCGACAAGGCCAAGACCGCCTTCCTGTCGCGGATGAGCTATGAGCTGCGTACGCCGCTGACCTCGATCGGCGGCTT
CGGCGAAATGCTGCAGGCAGGCTATGCCGGCAAGCTCGGGGACCAGCAGCGCGCCTATGTCGATGCGATCATGGACTCGG
TCGCGGTGCTCGGCCGCCAGATCGACAATGTTCTCGACCTCGCGCAGGGCGAGGCGGGGACGCTGGCGATCGAGCGCGCG
CCGGTCGACGTCCGCGCGCTGCTCGAAAAGGCGCTCGACGACACGCGGCCTTTTGCCGATGCCGAGAAGGTCGAGCTGGT
CGGCAACATCGCCGCCGACCTCGGCACGATCGAGGGCGATGCGCCGCGGCTGTCGCGCCTCGTCGCCGGGCTGCTCGACA
ATGCGGTGCGCTTCACCGCGCCGGCGCGCAAATCGGCCGGTCGCGTGCTGCTTCACGCCGACGGCGACAAGCGCGGGATC
GACATCATCGTCTCCGACAACGGCCCCGGAATGCCCGAAGCCGCCGCCGCGGTCGCCAAGGGGCAACAGGCGGGCACCGA
CACCGGCGGCATCGGCCTCGCACTCGCGCGCCAGCTCGTCGCCGCGCACGGCGGGACGATGGAAGTGGTGAGCGAGGCGG
GACAGGGCACGCTGGTGCGCGTCAGCCTGCCGCGAGGGATGTGA

Upstream 100 bases:

>100_bases
GCCGATCCGCGCCGACATCCGATTGAAACATGACTCCATCGCCTTTAGGGCAGGCGATCATGCGCGCGGAACATCCGGAC
AAGCGAGGACATGAGGCGGG

Downstream 100 bases:

>100_bases
CAATCCTTATTGTCATCCTTTCGCGCTGGATCCCTGCGACGGCAGGGACCCATCTCCCGCGGGCTCAACTTGGCGCCGTC
CGGAGATGGGCCCCTGCCTC

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 787; Mature: 786

Protein sequence:

>787_residues
MSGTLSPTLLFALGLFAALWLLAGLWATLRGIAMQRRAAFAGGQAERLASLVEASPQLPVIVRADWRIEASDRLGRWLGL
DRGPRNFDELRGIGSGLDAASHDLLRQAILGAQRGAKPFQLSLKPEGSHRTIIVQGAAAPQAVGGAGSVLLWLSDATEGQ
QALAHARAERDEALAAFEALSGLIEAAPFPMWFRDTDLQLALVNAAYVRAVEARSATAVIDGGIELCETVAGVSAADAAD
AARAAGSAQQRTIPVTIEGERRIMRVVDVPLAPEGGRMIGIAGYAIDIQELESERGAHRRFVDTQRELLDRLSAAVAQFG
PDQGLAFANLPFRRLFGLDADDVGEARPFARLLDAWRERGRTPEVRDYPEWRQAHVDWFARAEASEEDWRLRDGTHLHVV
AQPTPDGGLLLIAEDKTEQVQLAGARDTLLRVRTATFDNLFEAVAVFAPDGRLHLWNQRFRRLWGVDEPTLAAHPRVDVL
MGGLADRLAKPNQISVVQEVIRAATLERQQRVGEIRFADGRHFDFASIPLPDGNALLIMLDITASRKMEGALRERNEALE
AADKAKTAFLSRMSYELRTPLTSIGGFGEMLQAGYAGKLGDQQRAYVDAIMDSVAVLGRQIDNVLDLAQGEAGTLAIERA
PVDVRALLEKALDDTRPFADAEKVELVGNIAADLGTIEGDAPRLSRLVAGLLDNAVRFTAPARKSAGRVLLHADGDKRGI
DIIVSDNGPGMPEAAAAVAKGQQAGTDTGGIGLALARQLVAAHGGTMEVVSEAGQGTLVRVSLPRGM

Sequences:

>Translated_787_residues
MSGTLSPTLLFALGLFAALWLLAGLWATLRGIAMQRRAAFAGGQAERLASLVEASPQLPVIVRADWRIEASDRLGRWLGL
DRGPRNFDELRGIGSGLDAASHDLLRQAILGAQRGAKPFQLSLKPEGSHRTIIVQGAAAPQAVGGAGSVLLWLSDATEGQ
QALAHARAERDEALAAFEALSGLIEAAPFPMWFRDTDLQLALVNAAYVRAVEARSATAVIDGGIELCETVAGVSAADAAD
AARAAGSAQQRTIPVTIEGERRIMRVVDVPLAPEGGRMIGIAGYAIDIQELESERGAHRRFVDTQRELLDRLSAAVAQFG
PDQGLAFANLPFRRLFGLDADDVGEARPFARLLDAWRERGRTPEVRDYPEWRQAHVDWFARAEASEEDWRLRDGTHLHVV
AQPTPDGGLLLIAEDKTEQVQLAGARDTLLRVRTATFDNLFEAVAVFAPDGRLHLWNQRFRRLWGVDEPTLAAHPRVDVL
MGGLADRLAKPNQISVVQEVIRAATLERQQRVGEIRFADGRHFDFASIPLPDGNALLIMLDITASRKMEGALRERNEALE
AADKAKTAFLSRMSYELRTPLTSIGGFGEMLQAGYAGKLGDQQRAYVDAIMDSVAVLGRQIDNVLDLAQGEAGTLAIERA
PVDVRALLEKALDDTRPFADAEKVELVGNIAADLGTIEGDAPRLSRLVAGLLDNAVRFTAPARKSAGRVLLHADGDKRGI
DIIVSDNGPGMPEAAAAVAKGQQAGTDTGGIGLALARQLVAAHGGTMEVVSEAGQGTLVRVSLPRGM
>Mature_786_residues
SGTLSPTLLFALGLFAALWLLAGLWATLRGIAMQRRAAFAGGQAERLASLVEASPQLPVIVRADWRIEASDRLGRWLGLD
RGPRNFDELRGIGSGLDAASHDLLRQAILGAQRGAKPFQLSLKPEGSHRTIIVQGAAAPQAVGGAGSVLLWLSDATEGQQ
ALAHARAERDEALAAFEALSGLIEAAPFPMWFRDTDLQLALVNAAYVRAVEARSATAVIDGGIELCETVAGVSAADAADA
ARAAGSAQQRTIPVTIEGERRIMRVVDVPLAPEGGRMIGIAGYAIDIQELESERGAHRRFVDTQRELLDRLSAAVAQFGP
DQGLAFANLPFRRLFGLDADDVGEARPFARLLDAWRERGRTPEVRDYPEWRQAHVDWFARAEASEEDWRLRDGTHLHVVA
QPTPDGGLLLIAEDKTEQVQLAGARDTLLRVRTATFDNLFEAVAVFAPDGRLHLWNQRFRRLWGVDEPTLAAHPRVDVLM
GGLADRLAKPNQISVVQEVIRAATLERQQRVGEIRFADGRHFDFASIPLPDGNALLIMLDITASRKMEGALRERNEALEA
ADKAKTAFLSRMSYELRTPLTSIGGFGEMLQAGYAGKLGDQQRAYVDAIMDSVAVLGRQIDNVLDLAQGEAGTLAIERAP
VDVRALLEKALDDTRPFADAEKVELVGNIAADLGTIEGDAPRLSRLVAGLLDNAVRFTAPARKSAGRVLLHADGDKRGID
IIVSDNGPGMPEAAAAVAKGQQAGTDTGGIGLALARQLVAAHGGTMEVVSEAGQGTLVRVSLPRGM

Specific function: Required for cell division and growth. It catalyzes the phosphorylation of CtrA and activates transcription in vitro of the cell cycle-regulated fliF promoter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=321, Percent_Identity=28.3489096573209, Blast_Score=116, Evalue=5e-27,
Organism=Escherichia coli, GI1788713, Length=277, Percent_Identity=28.158844765343, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI1789149, Length=236, Percent_Identity=29.2372881355932, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1786912, Length=252, Percent_Identity=28.968253968254, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI48994928, Length=286, Percent_Identity=29.020979020979, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI87081816, Length=235, Percent_Identity=31.063829787234, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788393, Length=235, Percent_Identity=27.6595744680851, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786600, Length=274, Percent_Identity=22.992700729927, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082128, Length=237, Percent_Identity=27.0042194092827, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1786783, Length=241, Percent_Identity=25.3112033195021, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 84521; Mature: 84390

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGTLSPTLLFALGLFAALWLLAGLWATLRGIAMQRRAAFAGGQAERLASLVEASPQLPV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCE
IVRADWRIEASDRLGRWLGLDRGPRNFDELRGIGSGLDAASHDLLRQAILGAQRGAKPFQ
EEECCCEEECHHHHHHHHCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEE
LSLKPEGSHRTIIVQGAAAPQAVGGAGSVLLWLSDATEGQQALAHARAERDEALAAFEAL
EEECCCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
SGLIEAAPFPMWFRDTDLQLALVNAAYVRAVEARSATAVIDGGIELCETVAGVSAADAAD
HHHHHHCCCCEEEECCCCEEEEEHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCHHHHHH
AARAAGSAQQRTIPVTIEGERRIMRVVDVPLAPEGGRMIGIAGYAIDIQELESERGAHRR
HHHHCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCEEEEEEEEEEHHHHHHHCCHHHH
FVDTQRELLDRLSAAVAQFGPDQGLAFANLPFRRLFGLDADDVGEARPFARLLDAWRERG
HHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCC
RTPEVRDYPEWRQAHVDWFARAEASEEDWRLRDGTHLHVVAQPTPDGGLLLIAEDKTEQV
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCEECCCCEEEEEEECCCCCCEEEEECCCCCEE
QLAGARDTLLRVRTATFDNLFEAVAVFAPDGRLHLWNQRFRRLWGVDEPTLAAHPRVDVL
EECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCHHHH
MGGLADRLAKPNQISVVQEVIRAATLERQQRVGEIRFADGRHFDFASIPLPDGNALLIML
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEECCCCCCCEEEEEE
DITASRKMEGALRERNEALEAADKAKTAFLSRMSYELRTPLTSIGGFGEMLQAGYAGKLG
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHCCCCCCCC
DQQRAYVDAIMDSVAVLGRQIDNVLDLAQGEAGTLAIERAPVDVRALLEKALDDTRPFAD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCC
AEKVELVGNIAADLGTIEGDAPRLSRLVAGLLDNAVRFTAPARKSAGRVLLHADGDKRGI
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHEECCCCCCCCCEEEEEECCCCCCE
DIIVSDNGPGMPEAAAAVAKGQQAGTDTGGIGLALARQLVAAHGGTMEVVSEAGQGTLVR
EEEECCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCEEEE
VSLPRGM
EECCCCC
>Mature Secondary Structure 
SGTLSPTLLFALGLFAALWLLAGLWATLRGIAMQRRAAFAGGQAERLASLVEASPQLPV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCE
IVRADWRIEASDRLGRWLGLDRGPRNFDELRGIGSGLDAASHDLLRQAILGAQRGAKPFQ
EEECCCEEECHHHHHHHHCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEE
LSLKPEGSHRTIIVQGAAAPQAVGGAGSVLLWLSDATEGQQALAHARAERDEALAAFEAL
EEECCCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
SGLIEAAPFPMWFRDTDLQLALVNAAYVRAVEARSATAVIDGGIELCETVAGVSAADAAD
HHHHHHCCCCEEEECCCCEEEEEHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCHHHHHH
AARAAGSAQQRTIPVTIEGERRIMRVVDVPLAPEGGRMIGIAGYAIDIQELESERGAHRR
HHHHCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCEEEEEEEEEEHHHHHHHCCHHHH
FVDTQRELLDRLSAAVAQFGPDQGLAFANLPFRRLFGLDADDVGEARPFARLLDAWRERG
HHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCC
RTPEVRDYPEWRQAHVDWFARAEASEEDWRLRDGTHLHVVAQPTPDGGLLLIAEDKTEQV
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCEECCCCEEEEEEECCCCCCEEEEECCCCCEE
QLAGARDTLLRVRTATFDNLFEAVAVFAPDGRLHLWNQRFRRLWGVDEPTLAAHPRVDVL
EECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCHHHH
MGGLADRLAKPNQISVVQEVIRAATLERQQRVGEIRFADGRHFDFASIPLPDGNALLIML
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEECCCCCCCEEEEEE
DITASRKMEGALRERNEALEAADKAKTAFLSRMSYELRTPLTSIGGFGEMLQAGYAGKLG
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHCCCCCCCC
DQQRAYVDAIMDSVAVLGRQIDNVLDLAQGEAGTLAIERAPVDVRALLEKALDDTRPFAD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCC
AEKVELVGNIAADLGTIEGDAPRLSRLVAGLLDNAVRFTAPARKSAGRVLLHADGDKRGI
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHEECCCCCCCCCEEEEEECCCCCCE
DIIVSDNGPGMPEAAAAVAKGQQAGTDTGGIGLALARQLVAAHGGTMEVVSEAGQGTLVR
EEEECCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCEEEE
VSLPRGM
EECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10557274; 11259647 [H]