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The map label for this gene is msrB2 [H]

Identifier: 103485621

GI number: 103485621

Start: 121993

End: 122436

Strand: Direct

Name: msrB2 [H]

Synonym: Sala_0125

Alternate gene names: 103485621

Gene position: 121993-122436 (Clockwise)

Preceding gene: 103485620

Following gene: 103485622

Centisome position: 3.65

GC content: 60.59

Gene sequence:

>444_bases
ATGACCTACCTCAAGACCAGCGAAGCCATTGCGAAGCTGACGCCCCAACAGCGCCATGTCACCCAGGAAGGCGGCACCGA
GCGTGCCGGCAGTGGGGAACTGCTGCACAATAAGGAGCCCGGCATCTACGTCGATATCGTCAGCGGCGAGCCCTTGTTCG
CCTCGACCGACAAATTCGATTCCGGCAGTGGATGGCCGAGCTTCACCAAGCCCATCGTCCCCGCCAATGTCGATGAAATA
CGCGACGACAGCTACGGGATGATCCGCACCGAGGTGCGCTCGGCTCATGGCGACAGCCACTTGGGACATGTGTTTCCCGA
CGGTCCGCGCGACCGTGGCGGCCAGCGCTACTGCATCAACTCGGCTTCACTCCGCTTCGTCCACCGCGATGACATGGAAG
CCGAGGGCTATTCCGAATTTCTGAACCAGATCGAGGAGAATTGA

Upstream 100 bases:

>100_bases
CTGAGCCAAATTTCGAATTTCGGGACTGTCTCCACCGGCGCGCATGCGGCGCACCGGGGTGGAAAGACGTGCCGCAACTG
TCAGACAAAGGAGATATCGA

Downstream 100 bases:

>100_bases
TCATGACCGAACGTTCCATCCTTGCCGGCGGCTGCTTCTGGGGCATGCAGGACCTGATCCGCAAACTCCCCGGCGTCGTC
AGCACCCGTGTCGGTTACAG

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase 2 [H]

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MTYLKTSEAIAKLTPQQRHVTQEGGTERAGSGELLHNKEPGIYVDIVSGEPLFASTDKFDSGSGWPSFTKPIVPANVDEI
RDDSYGMIRTEVRSAHGDSHLGHVFPDGPRDRGGQRYCINSASLRFVHRDDMEAEGYSEFLNQIEEN

Sequences:

>Translated_147_residues
MTYLKTSEAIAKLTPQQRHVTQEGGTERAGSGELLHNKEPGIYVDIVSGEPLFASTDKFDSGSGWPSFTKPIVPANVDEI
RDDSYGMIRTEVRSAHGDSHLGHVFPDGPRDRGGQRYCINSASLRFVHRDDMEAEGYSEFLNQIEEN
>Mature_146_residues
TYLKTSEAIAKLTPQQRHVTQEGGTERAGSGELLHNKEPGIYVDIVSGEPLFASTDKFDSGSGWPSFTKPIVPANVDEIR
DDSYGMIRTEVRSAHGDSHLGHVFPDGPRDRGGQRYCINSASLRFVHRDDMEAEGYSEFLNQIEEN

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=128, Percent_Identity=54.6875, Blast_Score=129, Evalue=8e-31,
Organism=Homo sapiens, GI301336162, Length=128, Percent_Identity=54.6875, Blast_Score=129, Evalue=8e-31,
Organism=Homo sapiens, GI73089054, Length=128, Percent_Identity=54.6875, Blast_Score=129, Evalue=8e-31,
Organism=Homo sapiens, GI37620216, Length=128, Percent_Identity=54.6875, Blast_Score=128, Evalue=2e-30,
Organism=Homo sapiens, GI117606353, Length=134, Percent_Identity=47.7611940298507, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1788077, Length=128, Percent_Identity=49.21875, Blast_Score=127, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI115532676, Length=128, Percent_Identity=42.96875, Blast_Score=104, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17553450, Length=128, Percent_Identity=42.96875, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6319816, Length=122, Percent_Identity=37.7049180327869, Blast_Score=85, Evalue=5e-18,
Organism=Drosophila melanogaster, GI45553335, Length=120, Percent_Identity=49.1666666666667, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21356369, Length=120, Percent_Identity=49.1666666666667, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24645799, Length=120, Percent_Identity=49.1666666666667, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI221378664, Length=121, Percent_Identity=47.9338842975207, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI221378662, Length=128, Percent_Identity=45.3125, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24645804, Length=131, Percent_Identity=45.0381679389313, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24645801, Length=131, Percent_Identity=45.0381679389313, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 16327; Mature: 16196

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYLKTSEAIAKLTPQQRHVTQEGGTERAGSGELLHNKEPGIYVDIVSGEPLFASTDKFD
CCCCCCCHHHHHCCCCHHHHHHCCCCCCCCCCCEEECCCCCEEEEEECCCCCEECCCCCC
SGSGWPSFTKPIVPANVDEIRDDSYGMIRTEVRSAHGDSHLGHVFPDGPRDRGGQRYCIN
CCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEC
SASLRFVHRDDMEAEGYSEFLNQIEEN
CCEEEEEECCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TYLKTSEAIAKLTPQQRHVTQEGGTERAGSGELLHNKEPGIYVDIVSGEPLFASTDKFD
CCCCCCHHHHHCCCCHHHHHHCCCCCCCCCCCEEECCCCCEEEEEECCCCCEECCCCCC
SGSGWPSFTKPIVPANVDEIRDDSYGMIRTEVRSAHGDSHLGHVFPDGPRDRGGQRYCIN
CCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEC
SASLRFVHRDDMEAEGYSEFLNQIEEN
CCEEEEEECCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]