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The map label for this gene is glnH [H]

Identifier: 99082838

GI number: 99082838

Start: 3166064

End: 3167128

Strand: Direct

Name: glnH [H]

Synonym: TM1040_2998

Alternate gene names: 99082838

Gene position: 3166064-3167128 (Clockwise)

Preceding gene: 99082837

Following gene: 99082840

Centisome position: 98.91

GC content: 57.09

Gene sequence:

>1065_bases
ATGACCCTGCGCTCTATTTGGTTTTGTCTTGTCACAGTGTTGATGACCCTTCCAGCCTTGCCGCTGCGCGCGCAGGAACT
GGTGGTCAACACGGTTACCCGTCCGCCGTTTTCAATGCCGGTCGGAGAGCATGAGACGGGTTTTACCATGGATTTGATCC
GCGAGGTCTCGCAACGCCTCGGTTGGGACATCCAGATCAATCGGGTCGATAACTTTGCGCAGATGCTCGAAGAGGTCGAA
CGCGGCGAGGCCGATATGGCGGCGGCAAACATCTCCATCACGGCCGGGCGTGAAGCGGTAATGGATTTCAGTCAGCCCAT
CTTTGAAAGCGGCCTGCAGATCATGCTGCATCAGGACGATGTGTCAGAGCCAAGCCTGATTTCGGCGCTGATGTCGTGGG
ATCTCTTCGCGGCCATCGCAATCGCATTTGTGCTCTTGCTGGTGGGCGGCATGCTTATGTGGGTGTTTGAGCGCCGAGCG
CAGCCCTATTTTGATCGCCCGTTGAAAGATGCGTGGTTCCCATCTTTCTGGTGGGCTCTCAATCTGGTGGTGAACGGTGG
TTTTGAAGAGCGGGTGCCGCGCAGCGCGCTTGGGCGGGTTTTTGGTGTTCTGCTGGTTCTCTCATCATTGTTCGTGGTGT
CGGTCTTTGTCGCCAAAATCACCGCCGCCATGACCGTCGAGGCGATCAACGGGTCGGTGAATTCGGTGAACGACCTCTAC
GGCAAGCGCGTCGGCACGATCCAGGGCTCCACCGCGGCAGGATTTCTGGATCGTCGTGAAATCGACTATGTGGCGTTTCC
GGGGCTCGATAAGATGCTCGAGGACTTTGAAGACGGCGATACGCGCATAGTCGTGTTTGATGCGCCGGTGCTCAACCACT
ACGTCAAAACCGACGGTGCGGGGATCGGGCATGTGATGGGGCGGAAGTTCCTGACGGAATACTACGGGATTATCTTCCCG
CAGGGGTCCGACATGGTGGAGCCGTTCAATCGTGCCTTGCTGAAGATGCAGGAAGACGGCGCCTACGAGACGCTCTATCG
AAAGTGGTTTGGTCAGAGTTTCTAG

Upstream 100 bases:

>100_bases
GCAATCCTTGCAGAACATCGCACCGCCTGAGCACTGAGGACTTGAAAAAATCCCCGTAGCCCTTCTAAGCAGTCTCACCG
TTTCTAGTGAGAACCGCTCC

Downstream 100 bases:

>100_bases
ACCCTGATTGGATCTTTTGACCCACGCCAGCGATTTCTGAGCAAGCGCGGGTTAATGCGGGGCGCTGTTTTCGTCCACCG
CGCTCAATTCATCACCAAAG

Product: extracellular solute-binding protein

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: GlnBP [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MTLRSIWFCLVTVLMTLPALPLRAQELVVNTVTRPPFSMPVGEHETGFTMDLIREVSQRLGWDIQINRVDNFAQMLEEVE
RGEADMAAANISITAGREAVMDFSQPIFESGLQIMLHQDDVSEPSLISALMSWDLFAAIAIAFVLLLVGGMLMWVFERRA
QPYFDRPLKDAWFPSFWWALNLVVNGGFEERVPRSALGRVFGVLLVLSSLFVVSVFVAKITAAMTVEAINGSVNSVNDLY
GKRVGTIQGSTAAGFLDRREIDYVAFPGLDKMLEDFEDGDTRIVVFDAPVLNHYVKTDGAGIGHVMGRKFLTEYYGIIFP
QGSDMVEPFNRALLKMQEDGAYETLYRKWFGQSF

Sequences:

>Translated_354_residues
MTLRSIWFCLVTVLMTLPALPLRAQELVVNTVTRPPFSMPVGEHETGFTMDLIREVSQRLGWDIQINRVDNFAQMLEEVE
RGEADMAAANISITAGREAVMDFSQPIFESGLQIMLHQDDVSEPSLISALMSWDLFAAIAIAFVLLLVGGMLMWVFERRA
QPYFDRPLKDAWFPSFWWALNLVVNGGFEERVPRSALGRVFGVLLVLSSLFVVSVFVAKITAAMTVEAINGSVNSVNDLY
GKRVGTIQGSTAAGFLDRREIDYVAFPGLDKMLEDFEDGDTRIVVFDAPVLNHYVKTDGAGIGHVMGRKFLTEYYGIIFP
QGSDMVEPFNRALLKMQEDGAYETLYRKWFGQSF
>Mature_353_residues
TLRSIWFCLVTVLMTLPALPLRAQELVVNTVTRPPFSMPVGEHETGFTMDLIREVSQRLGWDIQINRVDNFAQMLEEVER
GEADMAAANISITAGREAVMDFSQPIFESGLQIMLHQDDVSEPSLISALMSWDLFAAIAIAFVLLLVGGMLMWVFERRAQ
PYFDRPLKDAWFPSFWWALNLVVNGGFEERVPRSALGRVFGVLLVLSSLFVVSVFVAKITAAMTVEAINGSVNSVNDLYG
KRVGTIQGSTAAGFLDRREIDYVAFPGLDKMLEDFEDGDTRIVVFDAPVLNHYVKTDGAGIGHVMGRKFLTEYYGIIFPQ
GSDMVEPFNRALLKMQEDGAYETLYRKWFGQSF

Specific function: Involved in a glutamine-transport system glnHPQ [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Homo sapiens, GI74275354, Length=406, Percent_Identity=24.8768472906404, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI134304851, Length=406, Percent_Identity=24.8768472906404, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI163659856, Length=376, Percent_Identity=25.531914893617, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI167001419, Length=373, Percent_Identity=24.6648793565684, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI134304848, Length=406, Percent_Identity=24.6305418719212, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI167001484, Length=373, Percent_Identity=24.6648793565684, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI164419734, Length=379, Percent_Identity=24.802110817942, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI163659858, Length=376, Percent_Identity=25.2659574468085, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI29029595, Length=384, Percent_Identity=25.5208333333333, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI164419736, Length=379, Percent_Identity=24.5382585751979, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI28416444, Length=373, Percent_Identity=22.7882037533512, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI4504117, Length=373, Percent_Identity=22.7882037533512, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI28605145, Length=377, Percent_Identity=23.6074270557029, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI28559003, Length=377, Percent_Identity=22.5464190981432, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI261278362, Length=377, Percent_Identity=22.5464190981432, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI11386137, Length=377, Percent_Identity=22.5464190981432, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI223278356, Length=340, Percent_Identity=24.1176470588235, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI153946391, Length=371, Percent_Identity=23.1805929919137, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI29029597, Length=403, Percent_Identity=24.8138957816377, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI62988346, Length=336, Percent_Identity=23.8095238095238, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI310113271, Length=336, Percent_Identity=23.2142857142857, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI167003331, Length=341, Percent_Identity=21.9941348973607, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1787031, Length=129, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71988861, Length=384, Percent_Identity=22.65625, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI25144707, Length=339, Percent_Identity=23.598820058997, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71989779, Length=371, Percent_Identity=22.6415094339623, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193208538, Length=339, Percent_Identity=20.0589970501475, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193209667, Length=262, Percent_Identity=24.8091603053435, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI62484334, Length=376, Percent_Identity=23.4042553191489, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24648559, Length=376, Percent_Identity=24.468085106383, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24648478, Length=350, Percent_Identity=24.8571428571429, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI116008052, Length=347, Percent_Identity=23.342939481268, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45549153, Length=385, Percent_Identity=23.1168831168831, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21355999, Length=349, Percent_Identity=21.4899713467049, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI116008056, Length=381, Percent_Identity=21.5223097112861, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24644257, Length=346, Percent_Identity=21.3872832369942, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640783, Length=382, Percent_Identity=21.9895287958115, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: 1440 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 460 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR005768
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: NA

Molecular weight: Translated: 39710; Mature: 39579

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRSIWFCLVTVLMTLPALPLRAQELVVNTVTRPPFSMPVGEHETGFTMDLIREVSQRL
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHC
GWDIQINRVDNFAQMLEEVERGEADMAAANISITAGREAVMDFSQPIFESGLQIMLHQDD
CCCEEEEHHHHHHHHHHHHHCCCHHHHHEEEEEECCHHHHHHHHHHHHHCCCEEEEECCC
VSEPSLISALMSWDLFAAIAIAFVLLLVGGMLMWVFERRAQPYFDRPLKDAWFPSFWWAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHH
NLVVNGGFEERVPRSALGRVFGVLLVLSSLFVVSVFVAKITAAMTVEAINGSVNSVNDLY
HHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
GKRVGTIQGSTAAGFLDRREIDYVAFPGLDKMLEDFEDGDTRIVVFDAPVLNHYVKTDGA
HCCCCCCCCCHHHCCHHHHCCCEEECCCHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCC
GIGHVMGRKFLTEYYGIIFPQGSDMVEPFNRALLKMQEDGAYETLYRKWFGQSF
CHHHHHHHHHHHHHHCEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TLRSIWFCLVTVLMTLPALPLRAQELVVNTVTRPPFSMPVGEHETGFTMDLIREVSQRL
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHC
GWDIQINRVDNFAQMLEEVERGEADMAAANISITAGREAVMDFSQPIFESGLQIMLHQDD
CCCEEEEHHHHHHHHHHHHHCCCHHHHHEEEEEECCHHHHHHHHHHHHHCCCEEEEECCC
VSEPSLISALMSWDLFAAIAIAFVLLLVGGMLMWVFERRAQPYFDRPLKDAWFPSFWWAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHH
NLVVNGGFEERVPRSALGRVFGVLLVLSSLFVVSVFVAKITAAMTVEAINGSVNSVNDLY
HHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
GKRVGTIQGSTAAGFLDRREIDYVAFPGLDKMLEDFEDGDTRIVVFDAPVLNHYVKTDGA
HCCCCCCCCCHHHCCHHHHCCCEEECCCHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCC
GIGHVMGRKFLTEYYGIIFPQGSDMVEPFNRALLKMQEDGAYETLYRKWFGQSF
CHHHHHHHHHHHHHHCEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: Translocates substrate across the membrane [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]