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The map label for this gene is fecD [C]

Identifier: 99082775

GI number: 99082775

Start: 3103310

End: 3104317

Strand: Direct

Name: fecD [C]

Synonym: TM1040_2935

Alternate gene names: 99082775

Gene position: 3103310-3104317 (Clockwise)

Preceding gene: 99082774

Following gene: 99082776

Centisome position: 96.95

GC content: 62.7

Gene sequence:

>1008_bases
ATGCGTCGCGGATCGCCCCTGTTGCTGCCAGCCTCTGGTCTGGCGCTGTTGCTTGCGATGGCCGCAGGGGTGCTCTGGGG
CACTGCTGACATCAGCTGGGGTGATCGGCTGGCGATCCTCATGCATGACGATGATGCACCGCGTGGGCTGTCGATGATCG
TCTGGCAATGGCGCATTCCGCGTGTGCTGGCGGTCGGAATGATCGGCGCCGGTTTGACGTTGGCTGGTCTCTTGATGCAG
ACCGCGCTGCGCAACCCGATGGCTGATCCTTATCTGATGGGAGTGTCCTCAGGAGCGTCGGCGGCGGCCGTTGGGGCGAT
CATCTGGTTTCCGTCGCAGATGACGGAAACACTTGGTGTCCCTCTGATCGCCTTTCTTGGTGCGGCAGCTGCTTTCCTGA
TGACGCTCACGCTCTCGCACCGGCGAGGGCGTGCGCTTGATCCTTTGGTGGTTATCCTCGCCGGTGTTGCGGTATCTCTT
ATGTTCCAGGCGCTTACGGCGTTCTTCCTCTATGTTGGTGATCCGCATGCCACGCGCAATGCGATGGGGTGGTTGATGGG
AACGGCGGCGGGAACCGATTGGGAGGAGCTACCACTTCTGGGCACCATCCTCGCCCTGTCGCTGGTGCTGGCGTTGCGCG
CGTCGTCCAAGCTGGATGCAACTTTGCTCGGGGATGAGCGCGCGCAATCACTGGGCGTCAATGTCGGGCGCATGCGACTG
CTGGTGTTCTTTGTCACAATCGCGCTGACCGGGGTGGCCGTTTCGATCGCGGGGATCGTTGGTTTTGTGGGGCTGATCCT
GCCCCATATGGCGCGCCTGTTGGTCGGCGCCCGCCACCGTGTCCTGATCCCACAGGCGGCCATCCTCGGGGCGATCACAC
TGATTCTTGTCGATCTGGCGTGTCGGGTCGTACTGGCGCCAGAGGAATTGCCGCTTGGCGTGTTGCTGGCGCTTCTGGCG
GCGCCGCCGTTCATCTATATCCTGCGGGGGATGGCCCATGCCCGATGA

Upstream 100 bases:

>100_bases
GGGGCGTTTTGTAACCGTCCCCTTCTCGGAAACGCTGTTGGGGATGCGCTTTGCCGATGGCGTGGAGACGGTGAACAATC
AACTTGCAAAGCTGCCGTAA

Downstream 100 bases:

>100_bases
TCCCATTCTCGAAATCCAGGATCTCTCCGTGGCAGTTGGTGGGCTCCCCTATGTTCGCGACCTCTCGCTTTGTGTGGAGC
GTGGGCGATTTCACGGTCTT

Product: transport system permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MRRGSPLLLPASGLALLLAMAAGVLWGTADISWGDRLAILMHDDDAPRGLSMIVWQWRIPRVLAVGMIGAGLTLAGLLMQ
TALRNPMADPYLMGVSSGASAAAVGAIIWFPSQMTETLGVPLIAFLGAAAAFLMTLTLSHRRGRALDPLVVILAGVAVSL
MFQALTAFFLYVGDPHATRNAMGWLMGTAAGTDWEELPLLGTILALSLVLALRASSKLDATLLGDERAQSLGVNVGRMRL
LVFFVTIALTGVAVSIAGIVGFVGLILPHMARLLVGARHRVLIPQAAILGAITLILVDLACRVVLAPEELPLGVLLALLA
APPFIYILRGMAHAR

Sequences:

>Translated_335_residues
MRRGSPLLLPASGLALLLAMAAGVLWGTADISWGDRLAILMHDDDAPRGLSMIVWQWRIPRVLAVGMIGAGLTLAGLLMQ
TALRNPMADPYLMGVSSGASAAAVGAIIWFPSQMTETLGVPLIAFLGAAAAFLMTLTLSHRRGRALDPLVVILAGVAVSL
MFQALTAFFLYVGDPHATRNAMGWLMGTAAGTDWEELPLLGTILALSLVLALRASSKLDATLLGDERAQSLGVNVGRMRL
LVFFVTIALTGVAVSIAGIVGFVGLILPHMARLLVGARHRVLIPQAAILGAITLILVDLACRVVLAPEELPLGVLLALLA
APPFIYILRGMAHAR
>Mature_335_residues
MRRGSPLLLPASGLALLLAMAAGVLWGTADISWGDRLAILMHDDDAPRGLSMIVWQWRIPRVLAVGMIGAGLTLAGLLMQ
TALRNPMADPYLMGVSSGASAAAVGAIIWFPSQMTETLGVPLIAFLGAAAAFLMTLTLSHRRGRALDPLVVILAGVAVSL
MFQALTAFFLYVGDPHATRNAMGWLMGTAAGTDWEELPLLGTILALSLVLALRASSKLDATLLGDERAQSLGVNVGRMRL
LVFFVTIALTGVAVSIAGIVGFVGLILPHMARLLVGARHRVLIPQAAILGAITLILVDLACRVVLAPEELPLGVLLALLA
APPFIYILRGMAHAR

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=292, Percent_Identity=36.986301369863, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1790741, Length=288, Percent_Identity=33.6805555555556, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1788004, Length=287, Percent_Identity=36.9337979094077, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786805, Length=281, Percent_Identity=37.0106761565836, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786804, Length=284, Percent_Identity=32.7464788732394, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786347, Length=277, Percent_Identity=30.3249097472924, Blast_Score=98, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35206; Mature: 35206

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRGSPLLLPASGLALLLAMAAGVLWGTADISWGDRLAILMHDDDAPRGLSMIVWQWRIP
CCCCCCCEECCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEHHHH
RVLAVGMIGAGLTLAGLLMQTALRNPMADPYLMGVSSGASAAAVGAIIWFPSQMTETLGV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHCCCHHHHHHHCH
PLIAFLGAAAAFLMTLTLSHRRGRALDPLVVILAGVAVSLMFQALTAFFLYVGDPHATRN
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
AMGWLMGTAAGTDWEELPLLGTILALSLVLALRASSKLDATLLGDERAQSLGVNVGRMRL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHCCCHHHHHH
LVFFVTIALTGVAVSIAGIVGFVGLILPHMARLLVGARHRVLIPQAAILGAITLILVDLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHH
CRVVLAPEELPLGVLLALLAAPPFIYILRGMAHAR
HHEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRRGSPLLLPASGLALLLAMAAGVLWGTADISWGDRLAILMHDDDAPRGLSMIVWQWRIP
CCCCCCCEECCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEHHHH
RVLAVGMIGAGLTLAGLLMQTALRNPMADPYLMGVSSGASAAAVGAIIWFPSQMTETLGV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHCCCHHHHHHHCH
PLIAFLGAAAAFLMTLTLSHRRGRALDPLVVILAGVAVSLMFQALTAFFLYVGDPHATRN
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
AMGWLMGTAAGTDWEELPLLGTILALSLVLALRASSKLDATLLGDERAQSLGVNVGRMRL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHCCCHHHHHH
LVFFVTIALTGVAVSIAGIVGFVGLILPHMARLLVGARHRVLIPQAAILGAITLILVDLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHH
CRVVLAPEELPLGVLLALLAAPPFIYILRGMAHAR
HHEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]