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The map label for this gene is divL [H]

Identifier: 99082681

GI number: 99082681

Start: 3008991

End: 3010541

Strand: Direct

Name: divL [H]

Synonym: TM1040_2841

Alternate gene names: 99082681

Gene position: 3008991-3010541 (Clockwise)

Preceding gene: 99082680

Following gene: 99082682

Centisome position: 94.0

GC content: 59.96

Gene sequence:

>1551_bases
ATGCAAGAATTGATGTCCGTCGAGTGGTTCATTCTGGTGACCCTCTGCATCGCCAGCGCAGCGGTTGCGGTCTGGTTTCT
GAACCCCAAGGCCGAGGCCAAGGGGATGGAGCACGAATTGCTGATCGCCGATGGCCGCACGGATGCGGTTTTCCTATTTG
ACGACCAGACGCTGATTGCCTGGTCATCGGGCGCGCGCAAGTTCCTCGATGACAATGCCGAAGATTTCAGTTGGGGCAAG
CTGCGGGACAAGCTGTCGCGCTCCTACCCGGGCCTACCGCAGTCACCCGGTTTCCTGCGCGATGTCGGCTCCCTGACACT
ATCTGGCACTGCAGAGGCAGACAACCGCGAGGCCCATTGCGAATGGATCGACGGCGTTACCCGTATTCAGCTGCGCCGCG
CCGCCTCGGACATCGGCCACGTCGGCGATGATCAGGAACTGACCACCCTGCGTGCAGCCGTGCATCAGGCCCCCTACCCC
GTTTGGCTGCAATCCGATGATGCCCGCGTCACCTGGACCAACCTTGCCTACGATCGTCTGAACCAGAAAATCCGTGGCCG
CGGCAATGATACCTCTGCACCTCTGTTTCCAAACCTCGACGCGCCGATGAACAGCGGTCGCGCGGAACGGATCTCCATCG
AGCTGCCGGAAACCGACAAGAAGCTCTGGTATAATGTCTCCACCACCGAGACCGAAGCCGGTTGGCTCTGTCATGCCATG
GACGTCAACGCCGTGGTGGATGCTGAGATCGCGCAACGCAACTTTGTGCAGACGCTGGCAAAAACCTTTGCGCAGCTTTC
CATCGGCCTTGCGATCTTTGACCGCAACCGCCAACTGGTCCTGTTCAACCCCGTCTTGATCGACCTCACCGCCCTGCCGG
CGAGTTTTCTGAGCTCGCGCCCCAACATGATGTCCTTCTTTGACCGCCTGCGCGACCAACGCATGATGCCGGAACCAAAG
AACTACTCGAGCTGGCGTCACCAGATGGCGGATCTCCTGGAGGCTGCCGCCGAGGGCCGCTATCAGGAAACATGGTCTTT
GCCCTCCGGGTCGGTCTATTCGGTCTCTGGCCGTCCACATCCTGATGGGGCCATCGCCTTTCTGTTTGAAGACATCACCG
CCGAAATCACTCTGACCCGTCAGTTCCGCTCTGAACTGGAGTTAGGCCAGTCGATCCTCGATCATATCGACGACGCCTTT
GCGGTCTTCGGCGCCGACGGTAGCATGGTCTATTCCAACACCGCCTACCACACGATGTGGAAAACCGACCCCGACGCAAG
CTTTGCCAAAATCACCATCACCGATGCCTGCCGCACCTGGCAGGAGCTCTCGGGACCAACCCCAACCTGGGGTGAAGTGC
GCGACTTTGTAGCCGGTGGCACCAGTGATCGTTCTGATTGGTGGTCTCGCGTGGACATGCGCAACGGTGAGCAGTTGCTC
TGCCGCGTGCAGTCGCTCCAGAACGGCTCCGTTATGGTCCGTTTCCAGCAGATCGACCTGCCGCTGGCGCCGCCAGAACA
AGAGCGTTTCGCCGTCCTCAAGGATAGCTGA

Upstream 100 bases:

>100_bases
CCGATACAGTTTTAACTATTCACTTTTGGGAAACCAGTTAAACTTCACTTAACCATTGTCATGGAAACTCAACGCAAGGA
GAAATAGCGAGGCTGTGTCC

Downstream 100 bases:

>100_bases
ACCCGCTTGCGGAGCCTCGCGCTGAACGTCATTGTGGCGCCATGACACAACGCTCTGCGACTTTCAGGCTGCCCAGCAGC
GACGCAACCACAGAATTGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MQELMSVEWFILVTLCIASAAVAVWFLNPKAEAKGMEHELLIADGRTDAVFLFDDQTLIAWSSGARKFLDDNAEDFSWGK
LRDKLSRSYPGLPQSPGFLRDVGSLTLSGTAEADNREAHCEWIDGVTRIQLRRAASDIGHVGDDQELTTLRAAVHQAPYP
VWLQSDDARVTWTNLAYDRLNQKIRGRGNDTSAPLFPNLDAPMNSGRAERISIELPETDKKLWYNVSTTETEAGWLCHAM
DVNAVVDAEIAQRNFVQTLAKTFAQLSIGLAIFDRNRQLVLFNPVLIDLTALPASFLSSRPNMMSFFDRLRDQRMMPEPK
NYSSWRHQMADLLEAAAEGRYQETWSLPSGSVYSVSGRPHPDGAIAFLFEDITAEITLTRQFRSELELGQSILDHIDDAF
AVFGADGSMVYSNTAYHTMWKTDPDASFAKITITDACRTWQELSGPTPTWGEVRDFVAGGTSDRSDWWSRVDMRNGEQLL
CRVQSLQNGSVMVRFQQIDLPLAPPEQERFAVLKDS

Sequences:

>Translated_516_residues
MQELMSVEWFILVTLCIASAAVAVWFLNPKAEAKGMEHELLIADGRTDAVFLFDDQTLIAWSSGARKFLDDNAEDFSWGK
LRDKLSRSYPGLPQSPGFLRDVGSLTLSGTAEADNREAHCEWIDGVTRIQLRRAASDIGHVGDDQELTTLRAAVHQAPYP
VWLQSDDARVTWTNLAYDRLNQKIRGRGNDTSAPLFPNLDAPMNSGRAERISIELPETDKKLWYNVSTTETEAGWLCHAM
DVNAVVDAEIAQRNFVQTLAKTFAQLSIGLAIFDRNRQLVLFNPVLIDLTALPASFLSSRPNMMSFFDRLRDQRMMPEPK
NYSSWRHQMADLLEAAAEGRYQETWSLPSGSVYSVSGRPHPDGAIAFLFEDITAEITLTRQFRSELELGQSILDHIDDAF
AVFGADGSMVYSNTAYHTMWKTDPDASFAKITITDACRTWQELSGPTPTWGEVRDFVAGGTSDRSDWWSRVDMRNGEQLL
CRVQSLQNGSVMVRFQQIDLPLAPPEQERFAVLKDS
>Mature_516_residues
MQELMSVEWFILVTLCIASAAVAVWFLNPKAEAKGMEHELLIADGRTDAVFLFDDQTLIAWSSGARKFLDDNAEDFSWGK
LRDKLSRSYPGLPQSPGFLRDVGSLTLSGTAEADNREAHCEWIDGVTRIQLRRAASDIGHVGDDQELTTLRAAVHQAPYP
VWLQSDDARVTWTNLAYDRLNQKIRGRGNDTSAPLFPNLDAPMNSGRAERISIELPETDKKLWYNVSTTETEAGWLCHAM
DVNAVVDAEIAQRNFVQTLAKTFAQLSIGLAIFDRNRQLVLFNPVLIDLTALPASFLSSRPNMMSFFDRLRDQRMMPEPK
NYSSWRHQMADLLEAAAEGRYQETWSLPSGSVYSVSGRPHPDGAIAFLFEDITAEITLTRQFRSELELGQSILDHIDDAF
AVFGADGSMVYSNTAYHTMWKTDPDASFAKITITDACRTWQELSGPTPTWGEVRDFVAGGTSDRSDWWSRVDMRNGEQLL
CRVQSLQNGSVMVRFQQIDLPLAPPEQERFAVLKDS

Specific function: Required for cell division and growth. It catalyzes the phosphorylation of CtrA and activates transcription in vitro of the cell cycle-regulated fliF promoter [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57945; Mature: 57945

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00027 HOMEOBOX_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQELMSVEWFILVTLCIASAAVAVWFLNPKAEAKGMEHELLIADGRTDAVFLFDDQTLIA
CCHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHCCCCEEEEEECCCCCEEEEEECCEEEE
WSSGARKFLDDNAEDFSWGKLRDKLSRSYPGLPQSPGFLRDVGSLTLSGTAEADNREAHC
ECCCCHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCEEEECCCCCCCCCCCH
EWIDGVTRIQLRRAASDIGHVGDDQELTTLRAAVHQAPYPVWLQSDDARVTWTNLAYDRL
HHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCCEEEEEHHHHHHH
NQKIRGRGNDTSAPLFPNLDAPMNSGRAERISIELPETDKKLWYNVSTTETEAGWLCHAM
HHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCEEEEEE
DVNAVVDAEIAQRNFVQTLAKTFAQLSIGLAIFDRNRQLVLFNPVLIDLTALPASFLSSR
CCCCEECHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEECCCEEEHHHCCHHHHCCC
PNMMSFFDRLRDQRMMPEPKNYSSWRHQMADLLEAAAEGRYQETWSLPSGSVYSVSGRPH
CHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCC
PDGAIAFLFEDITAEITLTRQFRSELELGQSILDHIDDAFAVFGADGSMVYSNTAYHTMW
CCCEEEEEEECCEEEEEEHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCEEEEEE
KTDPDASFAKITITDACRTWQELSGPTPTWGEVRDFVAGGTSDRSDWWSRVDMRNGEQLL
CCCCCCCEEEEEEHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHH
CRVQSLQNGSVMVRFQQIDLPLAPPEQERFAVLKDS
HHHHHCCCCCEEEEEEECCCCCCCCCCCCEEEEECC
>Mature Secondary Structure
MQELMSVEWFILVTLCIASAAVAVWFLNPKAEAKGMEHELLIADGRTDAVFLFDDQTLIA
CCHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHCCCCEEEEEECCCCCEEEEEECCEEEE
WSSGARKFLDDNAEDFSWGKLRDKLSRSYPGLPQSPGFLRDVGSLTLSGTAEADNREAHC
ECCCCHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCEEEECCCCCCCCCCCH
EWIDGVTRIQLRRAASDIGHVGDDQELTTLRAAVHQAPYPVWLQSDDARVTWTNLAYDRL
HHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCCEEEEEHHHHHHH
NQKIRGRGNDTSAPLFPNLDAPMNSGRAERISIELPETDKKLWYNVSTTETEAGWLCHAM
HHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCEEEEEE
DVNAVVDAEIAQRNFVQTLAKTFAQLSIGLAIFDRNRQLVLFNPVLIDLTALPASFLSSR
CCCCEECHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEECCCEEEHHHCCHHHHCCC
PNMMSFFDRLRDQRMMPEPKNYSSWRHQMADLLEAAAEGRYQETWSLPSGSVYSVSGRPH
CHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCC
PDGAIAFLFEDITAEITLTRQFRSELELGQSILDHIDDAFAVFGADGSMVYSNTAYHTMW
CCCEEEEEEECCEEEEEEHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCEEEEEE
KTDPDASFAKITITDACRTWQELSGPTPTWGEVRDFVAGGTSDRSDWWSRVDMRNGEQLL
CCCCCCCEEEEEEHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHH
CRVQSLQNGSVMVRFQQIDLPLAPPEQERFAVLKDS
HHHHHCCCCCEEEEEEECCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10557274; 11259647 [H]