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The map label for this gene is rssA [H]

Identifier: 99082574

GI number: 99082574

Start: 2877148

End: 2878533

Strand: Direct

Name: rssA [H]

Synonym: TM1040_2734

Alternate gene names: 99082574

Gene position: 2877148-2878533 (Clockwise)

Preceding gene: 99082573

Following gene: 99082575

Centisome position: 89.88

GC content: 61.62

Gene sequence:

>1386_bases
ATGAGCACGCCAATCCTGCTCCGGGGCTCTATTCGCAGGCGGCTCATTATCCAGTTGCTGACAGGGGCCGCGCTGTTGGC
GGGGCTGATGTTTTTGGTGGTTCAGAACTATGCGCGCGACCTCGCCGGGCAAAGTCAGGATGAAATCCTTTCGGCGTCTG
TGACCGCGATTCTTGATTCGGCATCGGTGCGCAACGGAGATCTGACCGTCGACATCCCCTATTTCGCCTTCTCCATGCTG
GGCAATATCAGCGAAGATCGCGTGTTCTACGCCATCACGCGCAACGGCGCCTTTATGACGGGATATTCCGATCTCCCGCG
CCCGGTCGCCAGCACCGGTCTCTCGCCGCGGTTTCAAACCGCGCAATATGATGGAGAGGAGATCCGCATGGCCACGGCCA
CCCGGCGTCTTTCTGTAAGCGGCACACCCGATTTCATCGAAGTGACCGTCGCCCAGACACGGTATGGTTTGCGACAGCAG
CTTGCTGGGATTTCGCAAACGGTGGCCGGGTTCGGCATTGGCTTTTTTGCGATTGCCGCCTTCTTTGGCATCCTCGCCGC
CCAATCCGCGATCCAGCCCCTGCGTGCGCTTGCCGGGGCTGTGTCGCGCCGGGGGCTGTCGGACCTGCGTCCGGTTTCGG
CTCCGGTGCCTGCCGAGATGGAATCTCTTGTGGGCGCGCTCAATGGTTTCATGAGCCGGCTCAAAACCTCTCTATCGCGC
TCGGAGGACCTGATCGCAGAGGCTGCACATCGCGTCCGGACCCCGCTTACAACCGTACGCACACAGGCCGAGATCACCCT
GCGGCGGGTCGACAAGCCCGAGAACCGCCAGGCCGTGCGCGAGATGATCCGCGCCATTGATGAGAGCAGCCGGGCCGCAG
GGCAGCTTTTGGATCACGCCATGGTTTCCTTTCGCTCGGACCACCTGGAGATGGAAGACGTAGAGCTCACACGCCTTGCC
CGCGACGCTGTTTCGCGCCTGCACCCGATGGCAGAGCTGCGCGACATCGACATAGAAATCACGCTGCCCGATGCGCACAT
GGTCGTCAAAGGCGACCCGATCTTGATGCAGAGCGCGCTTTTGAACCTTCTGGACAACGCCATCAAATACGCGCCCCCCG
ACAGCATCGTGCATGTCACCGTTCGCCCCACAGAGAGCGGCGCGGAGATCACTGTGCGCGACGAAGGCTCAGGCTTTCCA
AAGGCCGACATGGGCCGGTTGACACGCCGCTTTGTGCGGGGCGGCAATACCGAAACCGTTGTGGGGTCTGGTCTCGGTCT
CACGATTGCAAATGAGGTCGCCCGCGCCCATGGCGGCCGCCTGTTCCTGACCAATCACAGCGACAAAGGTGGCGCATGCG
CAAGCTTGTCTTTTCCCTTGGCCTGA

Upstream 100 bases:

>100_bases
ACGCGATCGAAGTCTATGTCGGACGGCTGCGCAAACACCTTGAAGGGGCGCGGGCGCAAATCGTCACCGTGCGTGGGCTG
GGCTACCGGCTGAGCCTCTC

Downstream 100 bases:

>100_bases
TTTTTTCGGGCCTGATCAGCCTTGCGCTTGCAGCGCCACTTCAGGCCTTTGAAATCGAGGATCAAATCAGCGTAGGCCCT
GCGGACGCGCGCCGGGTGCT

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MSTPILLRGSIRRRLIIQLLTGAALLAGLMFLVVQNYARDLAGQSQDEILSASVTAILDSASVRNGDLTVDIPYFAFSML
GNISEDRVFYAITRNGAFMTGYSDLPRPVASTGLSPRFQTAQYDGEEIRMATATRRLSVSGTPDFIEVTVAQTRYGLRQQ
LAGISQTVAGFGIGFFAIAAFFGILAAQSAIQPLRALAGAVSRRGLSDLRPVSAPVPAEMESLVGALNGFMSRLKTSLSR
SEDLIAEAAHRVRTPLTTVRTQAEITLRRVDKPENRQAVREMIRAIDESSRAAGQLLDHAMVSFRSDHLEMEDVELTRLA
RDAVSRLHPMAELRDIDIEITLPDAHMVVKGDPILMQSALLNLLDNAIKYAPPDSIVHVTVRPTESGAEITVRDEGSGFP
KADMGRLTRRFVRGGNTETVVGSGLGLTIANEVARAHGGRLFLTNHSDKGGACASLSFPLA

Sequences:

>Translated_461_residues
MSTPILLRGSIRRRLIIQLLTGAALLAGLMFLVVQNYARDLAGQSQDEILSASVTAILDSASVRNGDLTVDIPYFAFSML
GNISEDRVFYAITRNGAFMTGYSDLPRPVASTGLSPRFQTAQYDGEEIRMATATRRLSVSGTPDFIEVTVAQTRYGLRQQ
LAGISQTVAGFGIGFFAIAAFFGILAAQSAIQPLRALAGAVSRRGLSDLRPVSAPVPAEMESLVGALNGFMSRLKTSLSR
SEDLIAEAAHRVRTPLTTVRTQAEITLRRVDKPENRQAVREMIRAIDESSRAAGQLLDHAMVSFRSDHLEMEDVELTRLA
RDAVSRLHPMAELRDIDIEITLPDAHMVVKGDPILMQSALLNLLDNAIKYAPPDSIVHVTVRPTESGAEITVRDEGSGFP
KADMGRLTRRFVRGGNTETVVGSGLGLTIANEVARAHGGRLFLTNHSDKGGACASLSFPLA
>Mature_460_residues
STPILLRGSIRRRLIIQLLTGAALLAGLMFLVVQNYARDLAGQSQDEILSASVTAILDSASVRNGDLTVDIPYFAFSMLG
NISEDRVFYAITRNGAFMTGYSDLPRPVASTGLSPRFQTAQYDGEEIRMATATRRLSVSGTPDFIEVTVAQTRYGLRQQL
AGISQTVAGFGIGFFAIAAFFGILAAQSAIQPLRALAGAVSRRGLSDLRPVSAPVPAEMESLVGALNGFMSRLKTSLSRS
EDLIAEAAHRVRTPLTTVRTQAEITLRRVDKPENRQAVREMIRAIDESSRAAGQLLDHAMVSFRSDHLEMEDVELTRLAR
DAVSRLHPMAELRDIDIEITLPDAHMVVKGDPILMQSALLNLLDNAIKYAPPDSIVHVTVRPTESGAEITVRDEGSGFPK
ADMGRLTRRFVRGGNTETVVGSGLGLTIANEVARAHGGRLFLTNHSDKGGACASLSFPLA

Specific function: Member of the two-component regulatory system rssA/rssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/rssB regulates cellular fatty acid composition, hemolysin production and cell surface t

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=464, Percent_Identity=27.1551724137931, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1790551, Length=320, Percent_Identity=27.8125, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786783, Length=288, Percent_Identity=26.3888888888889, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788279, Length=311, Percent_Identity=24.7588424437299, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786912, Length=219, Percent_Identity=30.5936073059361, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI87082128, Length=314, Percent_Identity=24.8407643312102, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=25.2136752136752, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1790861, Length=261, Percent_Identity=29.5019157088123, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788393, Length=248, Percent_Identity=25, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1786600, Length=216, Percent_Identity=28.2407407407407, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789808, Length=244, Percent_Identity=25, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788549, Length=198, Percent_Identity=24.2424242424242, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788713, Length=236, Percent_Identity=24.5762711864407, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787894, Length=294, Percent_Identity=26.1904761904762, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1790346, Length=275, Percent_Identity=24, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49801; Mature: 49670

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPILLRGSIRRRLIIQLLTGAALLAGLMFLVVQNYARDLAGQSQDEILSASVTAILDS
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
ASVRNGDLTVDIPYFAFSMLGNISEDRVFYAITRNGAFMTGYSDLPRPVASTGLSPRFQT
CCCCCCCEEEEHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCCCHHHHCCCCCCCCC
AQYDGEEIRMATATRRLSVSGTPDFIEVTVAQTRYGLRQQLAGISQTVAGFGIGFFAIAA
CCCCCHHHEEEHHHEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFGILAAQSAIQPLRALAGAVSRRGLSDLRPVSAPVPAEMESLVGALNGFMSRLKTSLSR
HHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SEDLIAEAAHRVRTPLTTVRTQAEITLRRVDKPENRQAVREMIRAIDESSRAAGQLLDHA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
MVSFRSDHLEMEDVELTRLARDAVSRLHPMAELRDIDIEITLPDAHMVVKGDPILMQSAL
HHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHCCEEEEEECCCEEEECCCHHHHHHHH
LNLLDNAIKYAPPDSIVHVTVRPTESGAEITVRDEGSGFPKADMGRLTRRFVRGGNTETV
HHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEE
VGSGLGLTIANEVARAHGGRLFLTNHSDKGGACASLSFPLA
EECCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEECCCCCC
>Mature Secondary Structure 
STPILLRGSIRRRLIIQLLTGAALLAGLMFLVVQNYARDLAGQSQDEILSASVTAILDS
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
ASVRNGDLTVDIPYFAFSMLGNISEDRVFYAITRNGAFMTGYSDLPRPVASTGLSPRFQT
CCCCCCCEEEEHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCCCHHHHCCCCCCCCC
AQYDGEEIRMATATRRLSVSGTPDFIEVTVAQTRYGLRQQLAGISQTVAGFGIGFFAIAA
CCCCCHHHEEEHHHEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFGILAAQSAIQPLRALAGAVSRRGLSDLRPVSAPVPAEMESLVGALNGFMSRLKTSLSR
HHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SEDLIAEAAHRVRTPLTTVRTQAEITLRRVDKPENRQAVREMIRAIDESSRAAGQLLDHA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
MVSFRSDHLEMEDVELTRLARDAVSRLHPMAELRDIDIEITLPDAHMVVKGDPILMQSAL
HHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHCCEEEEEECCCEEEECCCHHHHHHHH
LNLLDNAIKYAPPDSIVHVTVRPTESGAEITVRDEGSGFPKADMGRLTRRFVRGGNTETV
HHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEE
VGSGLGLTIANEVARAHGGRLFLTNHSDKGGACASLSFPLA
EECCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA