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The map label for this gene is pepQ [H]

Identifier: 99082550

GI number: 99082550

Start: 2854428

End: 2855591

Strand: Direct

Name: pepQ [H]

Synonym: TM1040_2710

Alternate gene names: 99082550

Gene position: 2854428-2855591 (Clockwise)

Preceding gene: 99082549

Following gene: 99082551

Centisome position: 89.17

GC content: 62.2

Gene sequence:

>1164_bases
ATGCCTGAGACCTCCTTGATCTTTCCCGCGGCAGAATACCGAGGTCGCGTTGCGCGCCTTCAGGAGCATATGACTGCAGA
GGGCGTAGATGCGCTCTTGTTGACCACGGCCGCGGATGTGTTCTACGTGACTGGCTTTTTGACCCGGTTCTGGGAGAGCC
CTGCGCGACCATGGTTCGTCATCGTGCCTGTCTTGGGTGACCCGGTTGCGGTCATCCCCTCGATCGGCGCGCCCCTGATG
CAGCGCACATGGATCGAACAGATCCGAACTTGGGATGCGCCGGACCCGGAAGACGACGGCCGAACCTTGTTGATCGACAC
ATTGACGTCTCTGGTGCCAGATCACGGCAATGTGGCTCTACCTATGGGGTTAGAGACACATCTACGTATGGCACTTTTGG
ATTACCATGCCGTCCGCAGCGCGCTTGCCCCGCGCCGGGTGGTGGACGGAACCGAGATCCTCCAACGGGTGCGCGAGGTG
AAATCCGAGGCCGAGATCGCCAAGATCCGCAGCAGCTGCGCCATCGCGGGGCGCGCCTTTGATCGGGTGCCCGAGATTGC
CGGCGCAGGTCGCCCGCTTGATCAGGTGTTTCGCGAATTTCAGGCTCTATTGCTGGAGGAGGGCGCGGATTGGGTCAGTT
ATCTCGCGGGTGGCGCAGGGCTCGAGGGATATGGAGATGTGATCTCTCCAGCACCATCAGAGCCACTGGTACGCGGCGAC
ATCCTGATGCTCGACACGGGTGCGGTGCGCGAGGGGTATTTCTGTGATTTTGACCGCAACTATGCCATTGGCCCGGCCTC
TGATCTGGCAAAACGCACCCATGAGGCGCTGTGGTGCGCGACCCAAACCTGCCTTGAAGCCCTACGGCCGGGGATGCTCG
CGCGGGATGTACATCACATCCTATGTGATGCGTTGCGTGCCAAAGGGGCCACGCCGGGAGGCGGGCGGCTTGGGCATGGC
CTGGGGCTCACTTTGACGGAATGGCCTTCGTTCACTCCCAAGGACACCACCCCGCTGCGCGCAGGTATGGTGCTGACGCT
GGAACCCGGTGCGATCACTGGCGCGGATCGGATTCTCGTGCAGGAGGAGAACATCGTCCTACGCGACAGCGGCGCGGAGC
TCTTGTCCCCGCGCGCACCCGCAGAATTGCCGGAGCTGCTATGA

Upstream 100 bases:

>100_bases
GGAGGGGCGGGCATCGCAGCCTTGATCGCCGGTCTGGCGCTACCGCAAGACGCGCGCGTATTTGCGATCCTCAGCGAAGG
CCCGGAAGAAGGAACAGGCG

Downstream 100 bases:

>100_bases
TGACGCCTTTTCCCTACGAGATCGCAGAGGATCCGCGCCCGCGCCTGGGGCTCATTGCCTTGCAGGTGGATGAAACCATC
GAAGAGGATTTTCGGGTAAT

Product: peptidase M24

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MPETSLIFPAAEYRGRVARLQEHMTAEGVDALLLTTAADVFYVTGFLTRFWESPARPWFVIVPVLGDPVAVIPSIGAPLM
QRTWIEQIRTWDAPDPEDDGRTLLIDTLTSLVPDHGNVALPMGLETHLRMALLDYHAVRSALAPRRVVDGTEILQRVREV
KSEAEIAKIRSSCAIAGRAFDRVPEIAGAGRPLDQVFREFQALLLEEGADWVSYLAGGAGLEGYGDVISPAPSEPLVRGD
ILMLDTGAVREGYFCDFDRNYAIGPASDLAKRTHEALWCATQTCLEALRPGMLARDVHHILCDALRAKGATPGGGRLGHG
LGLTLTEWPSFTPKDTTPLRAGMVLTLEPGAITGADRILVQEENIVLRDSGAELLSPRAPAELPELL

Sequences:

>Translated_387_residues
MPETSLIFPAAEYRGRVARLQEHMTAEGVDALLLTTAADVFYVTGFLTRFWESPARPWFVIVPVLGDPVAVIPSIGAPLM
QRTWIEQIRTWDAPDPEDDGRTLLIDTLTSLVPDHGNVALPMGLETHLRMALLDYHAVRSALAPRRVVDGTEILQRVREV
KSEAEIAKIRSSCAIAGRAFDRVPEIAGAGRPLDQVFREFQALLLEEGADWVSYLAGGAGLEGYGDVISPAPSEPLVRGD
ILMLDTGAVREGYFCDFDRNYAIGPASDLAKRTHEALWCATQTCLEALRPGMLARDVHHILCDALRAKGATPGGGRLGHG
LGLTLTEWPSFTPKDTTPLRAGMVLTLEPGAITGADRILVQEENIVLRDSGAELLSPRAPAELPELL
>Mature_386_residues
PETSLIFPAAEYRGRVARLQEHMTAEGVDALLLTTAADVFYVTGFLTRFWESPARPWFVIVPVLGDPVAVIPSIGAPLMQ
RTWIEQIRTWDAPDPEDDGRTLLIDTLTSLVPDHGNVALPMGLETHLRMALLDYHAVRSALAPRRVVDGTEILQRVREVK
SEAEIAKIRSSCAIAGRAFDRVPEIAGAGRPLDQVFREFQALLLEEGADWVSYLAGGAGLEGYGDVISPAPSEPLVRGDI
LMLDTGAVREGYFCDFDRNYAIGPASDLAKRTHEALWCATQTCLEALRPGMLARDVHHILCDALRAKGATPGGGRLGHGL
GLTLTEWPSFTPKDTTPLRAGMVLTLEPGAITGADRILVQEENIVLRDSGAELLSPRAPAELPELL

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788728, Length=236, Percent_Identity=28.8135593220339, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 42052; Mature: 41920

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPETSLIFPAAEYRGRVARLQEHMTAEGVDALLLTTAADVFYVTGFLTRFWESPARPWFV
CCCCCEEECCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
IVPVLGDPVAVIPSIGAPLMQRTWIEQIRTWDAPDPEDDGRTLLIDTLTSLVPDHGNVAL
EEECCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHCCCCCCEEE
PMGLETHLRMALLDYHAVRSALAPRRVVDGTEILQRVREVKSEAEIAKIRSSCAIAGRAF
CCCHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRVPEIAGAGRPLDQVFREFQALLLEEGADWVSYLAGGAGLEGYGDVISPAPSEPLVRGD
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
ILMLDTGAVREGYFCDFDRNYAIGPASDLAKRTHEALWCATQTCLEALRPGMLARDVHHI
EEEEECCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LCDALRAKGATPGGGRLGHGLGLTLTEWPSFTPKDTTPLRAGMVLTLEPGAITGADRILV
HHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEE
QEENIVLRDSGAELLSPRAPAELPELL
ECCCEEEECCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
PETSLIFPAAEYRGRVARLQEHMTAEGVDALLLTTAADVFYVTGFLTRFWESPARPWFV
CCCCEEECCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
IVPVLGDPVAVIPSIGAPLMQRTWIEQIRTWDAPDPEDDGRTLLIDTLTSLVPDHGNVAL
EEECCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHCCCCCCEEE
PMGLETHLRMALLDYHAVRSALAPRRVVDGTEILQRVREVKSEAEIAKIRSSCAIAGRAF
CCCHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRVPEIAGAGRPLDQVFREFQALLLEEGADWVSYLAGGAGLEGYGDVISPAPSEPLVRGD
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
ILMLDTGAVREGYFCDFDRNYAIGPASDLAKRTHEALWCATQTCLEALRPGMLARDVHHI
EEEEECCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LCDALRAKGATPGGGRLGHGLGLTLTEWPSFTPKDTTPLRAGMVLTLEPGAITGADRILV
HHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEE
QEENIVLRDSGAELLSPRAPAELPELL
ECCCEEEECCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]