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The map label for this gene is lrp [C]

Identifier: 99082497

GI number: 99082497

Start: 2792625

End: 2793053

Strand: Reverse

Name: lrp [C]

Synonym: TM1040_2657

Alternate gene names: 99082497

Gene position: 2793053-2792625 (Counterclockwise)

Preceding gene: 99082498

Following gene: 99082496

Centisome position: 87.26

GC content: 60.61

Gene sequence:

>429_bases
GTGGACGATCTCGACCGTCGGATTGTCGCTGCTCTGCAGCATAATGCCCGCGAGTCCACCACCAAACTGGCGGCCAAGCT
GGGGGTGGCGCGCACCACAGTGCATGAGCGCATCACCCGGCTGGAAGAGCGTGGCATCATCGCGGGATATACCGTGGTGC
TGCGCGATCCCGACGAAGGTAACCGGGTCATGGTGGTGGTGCTCCTTGAGGTTCAGCAAAAGGAAACCGGACGCATTATC
AAGCGCTTGGAGGCCTACCCCGAAATTCGCCAATGCCTGTCGATCAATGGCGAATACGATCTGATGGTTTCGGCCGAGGC
ACCGCGCATCGAGGATCTGGACATTCTGGTCGATGAGGTCGGGCGCATTCCCGGCGTGCAGCGCACCAATACGCTGGTGG
TTTTTGGCCGCCGGATCGATCGCGTCTGA

Upstream 100 bases:

>100_bases
CACTGAGGCGGATGACCTCAAGGGGTTCACGGTTGGGGGCTATGCGTTTGACGCCGAGACTTCCGCGCCGCAGCGCCCGA
TCTTTGTGCGAGGCTGATCC

Downstream 100 bases:

>100_bases
CGGTATCTGAACAAATTGACGATTGATCCGTCATAGTGGCGTGATTTTACGTCACTCCGACAATTCCGGCCCTACAAATC
GAACAATTGAACCTGCACGC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MDDLDRRIVAALQHNARESTTKLAAKLGVARTTVHERITRLEERGIIAGYTVVLRDPDEGNRVMVVVLLEVQQKETGRII
KRLEAYPEIRQCLSINGEYDLMVSAEAPRIEDLDILVDEVGRIPGVQRTNTLVVFGRRIDRV

Sequences:

>Translated_142_residues
MDDLDRRIVAALQHNARESTTKLAAKLGVARTTVHERITRLEERGIIAGYTVVLRDPDEGNRVMVVVLLEVQQKETGRII
KRLEAYPEIRQCLSINGEYDLMVSAEAPRIEDLDILVDEVGRIPGVQRTNTLVVFGRRIDRV
>Mature_142_residues
MDDLDRRIVAALQHNARESTTKLAAKLGVARTTVHERITRLEERGIIAGYTVVLRDPDEGNRVMVVVLLEVQQKETGRII
KRLEAYPEIRQCLSINGEYDLMVSAEAPRIEDLDILVDEVGRIPGVQRTNTLVVFGRRIDRV

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=142, Percent_Identity=29.5774647887324, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI1790182, Length=143, Percent_Identity=27.972027972028, Blast_Score=64, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 16088; Mature: 16088

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDLDRRIVAALQHNARESTTKLAAKLGVARTTVHERITRLEERGIIAGYTVVLRDPDEG
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCC
NRVMVVVLLEVQQKETGRIIKRLEAYPEIRQCLSINGEYDLMVSAEAPRIEDLDILVDEV
CEEEEEEEEECCCCHHHHHHHHHHHCHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHH
GRIPGVQRTNTLVVFGRRIDRV
HCCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MDDLDRRIVAALQHNARESTTKLAAKLGVARTTVHERITRLEERGIIAGYTVVLRDPDEG
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCC
NRVMVVVLLEVQQKETGRIIKRLEAYPEIRQCLSINGEYDLMVSAEAPRIEDLDILVDEV
CEEEEEEEEECCCCHHHHHHHHHHHCHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHH
GRIPGVQRTNTLVVFGRRIDRV
HCCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA