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The map label for this gene is mcpA [H]

Identifier: 99082487

GI number: 99082487

Start: 2781272

End: 2782768

Strand: Reverse

Name: mcpA [H]

Synonym: TM1040_2647

Alternate gene names: 99082487

Gene position: 2782768-2781272 (Counterclockwise)

Preceding gene: 99082488

Following gene: 99082484

Centisome position: 86.94

GC content: 59.65

Gene sequence:

>1497_bases
ATGGTGACATCACCATTTCAAAAGGTTTATGTGATGTCGCAGATCCATCGAGACGAGCTGCTTTTCTGGTTCGGACTTGG
CGAGGAAGATCGTTCTTCTATTGTCGGTATGGCGCCCCTCGTGGAGCGCCACATTGATGCTGTTCTCGACGATTTCTACG
ACCTCTGCCTGTCGCGGCCGGAAACCAAAGGGTATTTTCCGACCGAACAGATCGTGGCCCATGCCAAGGCTGCGCAGCGC
GCCCATTGGGTGAAGCTCTTTTCGGGACGTTTTGACGACAGCTACATGAGCTCTGCCGACAAGGTTGGACGGGTGCATTT
TGAGGTTGATCTGCCGTTTCACCTGTTTCTGGGCGGCTATGCCACGGTGGGCGACCGTATCCTCAAGGTGGTCCTGACGC
AGAAAAACGGCTGGCGCGGCACCAAGGCAAGGATGAAACAGGCGCGCGCGCTGCAGCGGCTCATTCTGTTTGATTGCGAG
CGGGTGATCGCAGGGTATATCGACGCGCAGCTGCAGGAACGTGAAAAGGCGCTCACGGTCATGACCCAGGGGATTCAGCG
ATTGGAATCCGGGGATCTGACCACCGAGATGCCGTCGGGCGACAAGGGCGGCTTGCCGGAGCGCTATGACAATGTGCGTC
TGTCGTACAATCACCTGTTGCGCCACTGGTCGGGGATCCTGTCGGATGCCACCCGGCGCGCGCATTCGGTGGATGCCAAG
ATGGCCGAAACAGCGCGTATGACCCGCGAGATGGCGCATCGCTCGGGCGAACAGGCCAGCACCCTGAACGAGACTGTGAC
GTCTGTGAACAGCATGACCTGCAGCACACGACTAACCAGCGAGAAGGTCAACGATGCGGCCAAGCAGATCGAGGCCAACC
GACTTGTGGCCGAGGAGGGCGGCGCGGTTGTGCGCGATGCGATTACGGCGGTCGAACGGATCGAACAATCCTCCAGCCAG
ATCAACAAGATCGTTGATGTGATTGATGAAATCAGCTTTCAGACCACATTGCTTGCGCTCAATGCCGGGGTGGAGGCCGC
GCGCGCGGGCGAAGCTGGCAAAGGCTTTGCCGTCGTGGCATCGGAGGTGCGCGCGCTTGCAAGCCGGGCCACGGATGCGG
CGGATGATATCAAGAAACTGATTGCCACCAGCTCTGATCAGGTCCTCGAGGGGTGTCAATTGGTGCATCAGACCGGGGAG
CGGCTCGACAGCATCCGATCAAGCGCGGACAACGTGGCGCGGATCATGCAAGAGGTCGACGGTGTGATCTTTGAGCAGAC
CGGCCAGCTTGAAAACATCAGCGAACGGATGGAGCGGCTGGATCGATACACGCAGGACAGCGCCGATCAGGCCAATGAGG
TCTCCAGCACGGCGGATGCGCTGGCGCAGGACTCGGCGGCGCTGAAGGCCAGCATGGACGGGTTCAAAACCGGCGATATT
GCGTTGCGAGAGGCGGCGCAGGATAAGGAGTTCGAACGTCTCGCCAATCGCGGCTAG

Upstream 100 bases:

>100_bases
TCACTGTACGCCGGAGCAAACCATCCGTGGACTGCAAGAACCCATGCCGGTCTGGGCCCTGACGTCGCTTTGATAAGCCA
TTCGTTAAGGGTCTGAACCT

Downstream 100 bases:

>100_bases
GATGTGCGGGTGTCACGCGCAGCGCGTGTGAGACGCAAACCTGAAAGGCACCCAACTGTGCTTGGGGGCAATCCCGGCCA
GAGAGAGGCGCAATGCAGTC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MVTSPFQKVYVMSQIHRDELLFWFGLGEEDRSSIVGMAPLVERHIDAVLDDFYDLCLSRPETKGYFPTEQIVAHAKAAQR
AHWVKLFSGRFDDSYMSSADKVGRVHFEVDLPFHLFLGGYATVGDRILKVVLTQKNGWRGTKARMKQARALQRLILFDCE
RVIAGYIDAQLQEREKALTVMTQGIQRLESGDLTTEMPSGDKGGLPERYDNVRLSYNHLLRHWSGILSDATRRAHSVDAK
MAETARMTREMAHRSGEQASTLNETVTSVNSMTCSTRLTSEKVNDAAKQIEANRLVAEEGGAVVRDAITAVERIEQSSSQ
INKIVDVIDEISFQTTLLALNAGVEAARAGEAGKGFAVVASEVRALASRATDAADDIKKLIATSSDQVLEGCQLVHQTGE
RLDSIRSSADNVARIMQEVDGVIFEQTGQLENISERMERLDRYTQDSADQANEVSSTADALAQDSAALKASMDGFKTGDI
ALREAAQDKEFERLANRG

Sequences:

>Translated_498_residues
MVTSPFQKVYVMSQIHRDELLFWFGLGEEDRSSIVGMAPLVERHIDAVLDDFYDLCLSRPETKGYFPTEQIVAHAKAAQR
AHWVKLFSGRFDDSYMSSADKVGRVHFEVDLPFHLFLGGYATVGDRILKVVLTQKNGWRGTKARMKQARALQRLILFDCE
RVIAGYIDAQLQEREKALTVMTQGIQRLESGDLTTEMPSGDKGGLPERYDNVRLSYNHLLRHWSGILSDATRRAHSVDAK
MAETARMTREMAHRSGEQASTLNETVTSVNSMTCSTRLTSEKVNDAAKQIEANRLVAEEGGAVVRDAITAVERIEQSSSQ
INKIVDVIDEISFQTTLLALNAGVEAARAGEAGKGFAVVASEVRALASRATDAADDIKKLIATSSDQVLEGCQLVHQTGE
RLDSIRSSADNVARIMQEVDGVIFEQTGQLENISERMERLDRYTQDSADQANEVSSTADALAQDSAALKASMDGFKTGDI
ALREAAQDKEFERLANRG
>Mature_498_residues
MVTSPFQKVYVMSQIHRDELLFWFGLGEEDRSSIVGMAPLVERHIDAVLDDFYDLCLSRPETKGYFPTEQIVAHAKAAQR
AHWVKLFSGRFDDSYMSSADKVGRVHFEVDLPFHLFLGGYATVGDRILKVVLTQKNGWRGTKARMKQARALQRLILFDCE
RVIAGYIDAQLQEREKALTVMTQGIQRLESGDLTTEMPSGDKGGLPERYDNVRLSYNHLLRHWSGILSDATRRAHSVDAK
MAETARMTREMAHRSGEQASTLNETVTSVNSMTCSTRLTSEKVNDAAKQIEANRLVAEEGGAVVRDAITAVERIEQSSSQ
INKIVDVIDEISFQTTLLALNAGVEAARAGEAGKGFAVVASEVRALASRATDAADDIKKLIATSSDQVLEGCQLVHQTGE
RLDSIRSSADNVARIMQEVDGVIFEQTGQLENISERMERLDRYTQDSADQANEVSSTADALAQDSAALKASMDGFKTGDI
ALREAAQDKEFERLANRG

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=298, Percent_Identity=34.2281879194631, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1788195, Length=234, Percent_Identity=36.3247863247863, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1789453, Length=235, Percent_Identity=35.3191489361702, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI2367378, Length=232, Percent_Identity=37.5, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1788194, Length=251, Percent_Identity=34.2629482071713, Blast_Score=131, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 55042; Mature: 55042

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTSPFQKVYVMSQIHRDELLFWFGLGEEDRSSIVGMAPLVERHIDAVLDDFYDLCLSRP
CCCCHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ETKGYFPTEQIVAHAKAAQRAHWVKLFSGRFDDSYMSSADKVGRVHFEVDLPFHLFLGGY
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCEEEEEECCCHHHHHCCH
ATVGDRILKVVLTQKNGWRGTKARMKQARALQRLILFDCERVIAGYIDAQLQEREKALTV
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTQGIQRLESGDLTTEMPSGDKGGLPERYDNVRLSYNHLLRHWSGILSDATRRAHSVDAK
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAETARMTREMAHRSGEQASTLNETVTSVNSMTCSTRLTSEKVNDAAKQIEANRLVAEEG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GAVVRDAITAVERIEQSSSQINKIVDVIDEISFQTTLLALNAGVEAARAGEAGKGFAVVA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHH
SEVRALASRATDAADDIKKLIATSSDQVLEGCQLVHQTGERLDSIRSSADNVARIMQEVD
HHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GVIFEQTGQLENISERMERLDRYTQDSADQANEVSSTADALAQDSAALKASMDGFKTGDI
CHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
ALREAAQDKEFERLANRG
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVTSPFQKVYVMSQIHRDELLFWFGLGEEDRSSIVGMAPLVERHIDAVLDDFYDLCLSRP
CCCCHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ETKGYFPTEQIVAHAKAAQRAHWVKLFSGRFDDSYMSSADKVGRVHFEVDLPFHLFLGGY
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCEEEEEECCCHHHHHCCH
ATVGDRILKVVLTQKNGWRGTKARMKQARALQRLILFDCERVIAGYIDAQLQEREKALTV
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTQGIQRLESGDLTTEMPSGDKGGLPERYDNVRLSYNHLLRHWSGILSDATRRAHSVDAK
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAETARMTREMAHRSGEQASTLNETVTSVNSMTCSTRLTSEKVNDAAKQIEANRLVAEEG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GAVVRDAITAVERIEQSSSQINKIVDVIDEISFQTTLLALNAGVEAARAGEAGKGFAVVA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHH
SEVRALASRATDAADDIKKLIATSSDQVLEGCQLVHQTGERLDSIRSSADNVARIMQEVD
HHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GVIFEQTGQLENISERMERLDRYTQDSADQANEVSSTADALAQDSAALKASMDGFKTGDI
CHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
ALREAAQDKEFERLANRG
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]