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The map label for this gene is 99082312

Identifier: 99082312

GI number: 99082312

Start: 2612366

End: 2612851

Strand: Direct

Name: 99082312

Synonym: TM1040_2472

Alternate gene names: NA

Gene position: 2612366-2612851 (Clockwise)

Preceding gene: 99082309

Following gene: 99082313

Centisome position: 81.61

GC content: 58.23

Gene sequence:

>486_bases
ATGATATCTGTTGGAGACAAACTCCCCGAGGCCACCTTGACCCGACTGGGCGCCGAAGGCCCCGAAGCGGTTGCGATCCA
AGACCTCGCCAAGGGGCGCAAGCTGGCCATTTTCGCTGTGCCGGGCGCCTTTACTCCCACTTGCCACTCTGCGCATGTGC
CGAGTTTCATTCGTACCAAGGACCAGTTTGCGGCCAAAGGCGTTGACGAAATCATCTGTATCTCAGGCAACGATCCCTTC
GTCATGAAAGCCTGGGGCGAGGCCACCGGGGCAACCGAGGCGGGAATCACCATGCTGGCAGATGCGGAGTGCAGCTTTAC
CGATGCAATCGGGATGCGTTTTGACGCGCCACCAGCCGGGCTCATCGGGCGTTCCAAACGCTACGCAATGATCGTCGAGG
ATGGTGAGGTAAAAATCCTGCACCTCGAAGAAAGTCCGGGAACATGTGAAGTGTCTGCTGGTGAAGGGCTGCTGGATGCG
TTGTAA

Upstream 100 bases:

>100_bases
AGTTGATATACCGTTCGAGCGAACCCTACATGGAGGGCGCGCCGGGATGCAATTGCACAAAATCGCCAGGGCGCCCCAGA
GAGCATAAAGGATCGACCAC

Downstream 100 bases:

>100_bases
TCGGGTCAGTTCGAACCGCCCGTATTGCTAAGGCTTTGTACAAAGACGAATGACTGACGCGCACAGCACCGCGAAGCACC
CCGCCGCGATTATGGCCGAG

Product: thiol peroxidase (atypical 2-Cys peroxiredoxin)

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MISVGDKLPEATLTRLGAEGPEAVAIQDLAKGRKLAIFAVPGAFTPTCHSAHVPSFIRTKDQFAAKGVDEIICISGNDPF
VMKAWGEATGATEAGITMLADAECSFTDAIGMRFDAPPAGLIGRSKRYAMIVEDGEVKILHLEESPGTCEVSAGEGLLDA
L

Sequences:

>Translated_161_residues
MISVGDKLPEATLTRLGAEGPEAVAIQDLAKGRKLAIFAVPGAFTPTCHSAHVPSFIRTKDQFAAKGVDEIICISGNDPF
VMKAWGEATGATEAGITMLADAECSFTDAIGMRFDAPPAGLIGRSKRYAMIVEDGEVKILHLEESPGTCEVSAGEGLLDA
L
>Mature_161_residues
MISVGDKLPEATLTRLGAEGPEAVAIQDLAKGRKLAIFAVPGAFTPTCHSAHVPSFIRTKDQFAAKGVDEIICISGNDPF
VMKAWGEATGATEAGITMLADAECSFTDAIGMRFDAPPAGLIGRSKRYAMIVEDGEVKILHLEESPGTCEVSAGEGLLDA
L

Specific function: Unknown

COG id: COG0678

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI6912238, Length=144, Percent_Identity=38.1944444444444, Blast_Score=97, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6323138, Length=145, Percent_Identity=33.7931034482759, Blast_Score=81, Evalue=9e-17,
Organism=Drosophila melanogaster, GI78706776, Length=145, Percent_Identity=44.8275862068966, Blast_Score=126, Evalue=6e-30,
Organism=Drosophila melanogaster, GI78709078, Length=145, Percent_Identity=44.8275862068966, Blast_Score=126, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 16834; Mature: 16834

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVGDKLPEATLTRLGAEGPEAVAIQDLAKGRKLAIFAVPGAFTPTCHSAHVPSFIRTK
CCCCCCCCCHHHHHHHCCCCCCEEEEHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHCC
DQFAAKGVDEIICISGNDPFVMKAWGEATGATEAGITMLADAECSFTDAIGMRFDAPPAG
HHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCC
LIGRSKRYAMIVEDGEVKILHLEESPGTCEVSAGEGLLDAL
CCCCCCEEEEEEECCCEEEEEEECCCCEEEEECCCCHHHCC
>Mature Secondary Structure
MISVGDKLPEATLTRLGAEGPEAVAIQDLAKGRKLAIFAVPGAFTPTCHSAHVPSFIRTK
CCCCCCCCCHHHHHHHCCCCCCEEEEHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHCC
DQFAAKGVDEIICISGNDPFVMKAWGEATGATEAGITMLADAECSFTDAIGMRFDAPPAG
HHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCC
LIGRSKRYAMIVEDGEVKILHLEESPGTCEVSAGEGLLDAL
CCCCCCEEEEEEECCCEEEEEEECCCCEEEEECCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]